AROFF PLUS TABLET 10'S

How AROFF PLUS TABLET 10'S Works

• AROFF PLUS TABLET 10'S is a combination medication designed to alleviate pain and reduce fever. It contains two active ingredients: Aceclofenac and Paracetamol. Each component works through different mechanisms to achieve its therapeutic effect, providing comprehensive relief from various types of pain and inflammation.
• Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID). It primarily functions by inhibiting the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are crucial in the synthesis of prostaglandins, which are responsible for mediating pain, inflammation, and fever. By blocking the action of COX enzymes, Aceclofenac reduces the production of prostaglandins, thereby diminishing pain and inflammation at the site of injury or inflammation. Aceclofenac is particularly effective in managing pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis due to its anti-inflammatory properties.
• Paracetamol, also known as Acetaminophen, works through a different pathway. Its exact mechanism of action is not fully understood, but it is believed to primarily act centrally in the brain. Paracetamol inhibits prostaglandin synthesis in the central nervous system (CNS), which helps to reduce fever and alleviate pain. Unlike NSAIDs, Paracetamol has minimal anti-inflammatory effects in peripheral tissues. It is effective for reducing fever and relieving mild to moderate pain such as headaches, muscle aches, and toothaches. Paracetamol is often preferred over NSAIDs in individuals who are at risk of gastrointestinal side effects.
• When Aceclofenac and Paracetamol are combined in AROFF PLUS TABLET 10'S, they provide synergistic pain relief. Aceclofenac addresses the inflammatory component of pain by reducing prostaglandin production at the site of inflammation, while Paracetamol acts centrally to reduce the perception of pain and lower fever. This dual action makes AROFF PLUS TABLET 10'S effective in managing a wide range of painful conditions, including musculoskeletal pain, postoperative pain, and pain associated with inflammatory disorders. The combination allows for lower doses of each drug to be used, potentially reducing the risk of individual side effects while maximizing therapeutic benefits.
• In summary, AROFF PLUS TABLET 10'S works by leveraging the anti-inflammatory and analgesic properties of Aceclofenac and the antipyretic and analgesic effects of Paracetamol. This combination provides a balanced approach to pain management, effectively targeting both the cause and perception of pain and fever.

AROFF PLUS TABLET 10'S can cause several side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, stomach upset, diarrhea, constipation, headache, dizziness, drowsiness, and skin rash. Less common but potentially serious side effects include allergic reactions (such as swelling of the face, lips, tongue, or throat; difficulty breathing; hives), liver problems (such as yellowing of the skin or eyes, dark urine, abdominal pain), kidney problems (such as changes in urine output), and gastrointestinal bleeding (such as bloody or black stools, vomiting blood). Other possible side effects include increased heart rate, palpitations, anxiety, insomnia, tremors, confusion, and blurred vision. If you experience any severe or persistent side effects, discontinue use and consult your doctor immediately.

• If you miss a dose of AROFF PLUS TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep AROFF PLUS TAB 1X10 away from the reach of children and pets.
• Store AROFF PLUS TAB 1X10 at room temperature.

• Take Aroff Plus Tablet as prescribed by your doctor. Do not exceed the recommended dosage or duration. It's typically taken after food to minimize stomach upset.
• Inform your doctor about any pre-existing medical conditions, such as liver or kidney problems, and any other medications you are taking, including herbal supplements, before starting Aroff Plus Tablet.
• If you experience persistent side effects like nausea, vomiting, or abdominal pain, consult your doctor immediately. Do not self-treat or discontinue the medication without professional advice.
• Aroff Plus Tablet may cause drowsiness or dizziness in some individuals. Avoid driving or operating heavy machinery until you know how the medicine affects you. Limit alcohol consumption while taking this medication.
• Store Aroff Plus Tablet in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medicine if the packaging is damaged or the expiry date has passed.

• AROFF PLUS TABLET 10'S does not typically have significant interactions with food. It can be taken with or without food, as food generally does not affect its absorption or efficacy. However, if you experience any stomach upset, taking it with food might help.
• Always follow your doctor's specific instructions regarding the use of AROFF PLUS TABLET 10'S.