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ATGAM 250MG INJECTION
ATGAM 250MG INJECTION
By PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED
MRP
₹
21801.77
₹17441.42
20 % OFF
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Composition
Product Details
About ATGAM 250MG INJECTION
- ATGAM 250MG INJECTION contains special proteins known as Antithymocyte Immunoglobulins. These are purified proteins (gamma globulins) derived from horses that have been specially prepared to react against human white blood cells. This medicine is primarily used for individuals who have undergone an organ transplant, such as a kidney transplant. After a transplant, your body's immune system might identify the new organ as foreign and attempt to reject it. ATGAM 250MG INJECTION helps to moderate this strong immune reaction. It works by targeting and reducing the activity of certain white blood cells that are involved in attacking the transplanted organ, thereby aiding in the prevention or delay of organ rejection.
- ATGAM 250MG INJECTION is also prescribed for the treatment of a severe blood disorder called severe aplastic anemia. In this condition, the bone marrow fails to produce an adequate number of healthy blood cells, including red cells, white cells, and platelets. This often occurs because the immune system incorrectly targets and damages the bone marrow. ATGAM 250MG INJECTION suppresses the immune system, which helps to lessen this attack on the bone marrow. This can allow the bone marrow to recover its function and begin producing blood cells normally again, leading to improved blood counts and better overall health.
- By effectively managing the immune response, ATGAM 250MG INJECTION may contribute to reducing the necessity for high doses or extended use of other immunosuppressive medications, like corticosteroids. This is advantageous as prolonged high-dose steroid use can lead to numerous undesirable side effects. The administration of ATGAM 250MG INJECTION is done intravenously, meaning it is given directly into a vein, and requires careful supervision by trained healthcare professionals in a clinical setting.
- It is important to be aware of certain safety considerations before receiving ATGAM 250MG INJECTION. You should not be given this medicine if you have a history of severe allergic reactions to ATGAM 250MG INJECTION or any of its constituents. Since this medication impacts the immune system, it is generally advised to avoid receiving live vaccines during the course of treatment. Furthermore, if you have an active, significant infection, particularly one affecting your entire body, treatment with ATGAM 250MG INJECTION should typically be deferred until the infection has been properly managed and resolved. As with most medications, ATGAM 250MG INJECTION can cause side effects such as fever, chills, skin rash, or reactions at the injection site. Healthcare providers will closely monitor you during and after the infusion to address these potential issues and ensure your safety. The overarching goal is to safely control your immune system to protect your transplanted organ or support the recovery of your bone marrow function.
Uses of ATGAM 250MG INJECTION
- Helping prevent the body from rejecting transplanted organs.
- Treating Aplastic Anemia, a serious blood disorder.
- Preventing or treating rejection of transplanted kidneys.
- Treating Autoimmune Hemolytic Anemia, a specific blood disorder.
- Treating Myasthenia Gravis (a disorder causing muscle weakness).
Side Effects of ATGAM 250MG INJECTION
Side effects are unwanted symptoms caused by medicines. While all drugs can cause side effects, not everyone experiences them.
Safety Advice for ATGAM 250MG INJECTION
If you are taking ATGAM 250MG INJECTION and are planning to become pregnant or are already pregnant, it is important to discuss this with your healthcare professional.
Dosage of ATGAM 250MG INJECTION
- ATGAM 250MG INJECTION is a powerful medication that is always given directly into a vein. This is done as an intravenous infusion, meaning it's slowly dripped into your bloodstream over a period of time. Because of its nature and the need for careful monitoring, this treatment is always carried out in a hospital or a specialized clinical setting by trained healthcare professionals. It is never something you would administer yourself at home. The exact amount of ATGAM you receive, known as the dosage, and how quickly it is infused will be carefully decided by your doctor or healthcare provider. They will take several important factors into account when making this decision. These factors include the specific medical condition being treated, your overall health, your body weight, and how your body reacts to the medication during treatment. They will monitor you closely to ensure you are receiving the most effective and safest dose possible. The dosage and infusion rate are highly individualized to ensure the best possible outcome for you.
How to store ATGAM 250MG INJECTION?
- Keep ATGAM 250MG INJ 5ML away from the reach of children and pets.
- Store ATGAM 250MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.
Benefits of ATGAM 250MG INJECTION
- ATGAM 250MG INJECTION plays a vital role in preventing the body from rejecting the new organ. The immune system naturally sees the transplanted organ as foreign and attempts to attack it. ATGAM calms this reaction, significantly increasing the chances of successful transplantation and improving the long-term survival rate of the transplanted graft. This allows patients to live healthier lives with their new organs.
- Beyond transplantation, ATGAM 250MG INJECTION is also a key treatment for conditions like aplastic anemia and graft-versus-host disease (GVHD). In aplastic anemia, the immune system wrongly attacks the bone marrow, hindering the production of blood cells. By modulating the immune response, ATGAM stops this harmful attack, allowing the bone marrow to recover and restoring normal blood cell production. In GVHD, often seen after bone marrow transplants, donor immune cells attack the recipient's tissues. ATGAM helps control this aggressive reaction, reducing severe symptoms and minimizing damage to the body. Administered by injection under careful medical supervision, ATGAM 250MG INJECTION is a critical tool for specialists in managing these complex, life-threatening conditions, helping to alleviate symptoms and improve patient outcomes.
How to use ATGAM 250MG INJECTION
- ATGAM 250MG INJECTION is given as an injection directly into a vein. This is always done in a hospital or clinic by a trained healthcare professional. It's not something you would administer yourself at home. The medicine is slowly dripped into your vein over a period of time, which is called an infusion. The exact amount of ATGAM 250MG INJECTION you receive, and how fast it is given, is carefully decided by your doctor or nurse. They consider important things like the specific medical problem being treated, your overall health, your body weight, and how your body reacts to the first doses of the medicine. This ensures the treatment is as safe and effective as possible for you.
FAQs
How can I minimize the risk of infections while on ATGAM 250MG INJECTION therapy?
It is important to follow proper hygiene practices to reduce the risk of infections, such as frequent handwashing and avoiding close contact with contagious individuals. Inform your healthcare provider about any signs of infection, such as fever, cough, or sore throat, for prompt evaluation and appropriate treatment.
Can ATGAM 250MG INJECTION cause long-term kidney or liver damage?
While ATGAM 250MG INJECTION can potentially cause kidney or liver dysfunction, the risk of long-term damage is generally low. However, regular monitoring of kidney and liver function is important during the treatment to detect any early signs of impairment. Report any significant changes in urinary output or jaundice (yellowing of the skin or eyes) to your healthcare provider.
What steps can be taken to minimize infusion-related reactions?
Infusion-related reactions, such as fever and chills, can occur during ATGAM 250MG INJECTION administration. Slowing down the infusion rate, pre-medicating with antihistamines or corticosteroids, or using other supportive measures as your healthcare provider recommends can help minimize these reactions.
Is there an increased risk of developing malignancies with long-term ATGAM 250MG INJECTION use?
Prolonged use of immunosuppressive agents, including ATGAM 250MG INJECTION, may be associated with a slightly increased risk of developing certain malignancies. However, the overall risk is generally low. As your healthcare provider recommends, regular monitoring and screening for malignancies can help detect any potential issues early.
Can ATGAM 250MG INJECTION increase the risk of viral infections other than cytomegalovirus (CMV)?
While CMV reactivation is a known risk with ATGAM 250MG INJECTION therapy, there may also be an increased susceptibility to other viral infections. It is important to discuss any specific concerns or symptoms with your healthcare provider, who can evaluate the risk and provide appropriate guidance.
Are any specific tests or monitoring required for ATGAM 250MG INJECTION therapy patients?
Monitoring kidney function, liver function, blood counts, and viral markers may be necessary during ATGAM 250MG INJECTION treatment. Your healthcare provider will determine the appropriate monitoring schedule based on your condition and treatment plan.
Does ATGAM 250MG INJECTION interact with other medications?
Always consult with a qualified healthcare professional regarding the use of ATGAM 250MG INJECTION or any other medication you are taking. Inform your doctor about all your current medicines to manage potential interactions.
What important precautions or monitoring are needed during ATGAM 250MG INJECTION treatment?
Close infection surveillance is essential due to the increased risk associated with immunosuppression. Regular monitoring of liver function, kidney function, and blood counts is advised. Infusion-related reactions should be anticipated and managed appropriately. Pregnant and breastfeeding women, pediatric and geriatric patients require special consideration. Psychological effects should be monitored. Open communication with your healthcare team is key.
What is the main active ingredient in ATGAM 250MG INJECTION?
The main active ingredient in ATGAM 250MG INJECTION is Antithymocyte Immunoglobulins.
Why is ATGAM 250MG INJECTION prescribed for transplant patients?
ATGAM 250MG INJECTION is often prescribed for transplant patients to help prevent or treat organ rejection. It works by suppressing the immune system.
How does ATGAM 250MG INJECTION help in transplant cases?
In transplant cases, ATGAM 250MG INJECTION helps suppress the recipient's immune response to the transplanted organ, reducing the chance of the body rejecting it.
References
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Marketer / Manufacturer Details
PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED
Country of Origin -
India
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