AUVELIA TABLET 10'S

How AUVELIA TABLET 10'S Works

• AUVELIA TABLET 10'S is a medication designed to control serum phosphorus levels in adults with chronic kidney disease (CKD) on dialysis. It contains Ferric Citrate as its active ingredient. Understanding how AUVELIA works involves looking at the mechanism of action of Ferric Citrate.
• Ferric Citrate acts as a phosphate binder. When taken with meals, it binds to dietary phosphate in the gastrointestinal (GI) tract. This binding action is crucial because patients with CKD on dialysis often struggle to eliminate excess phosphorus, leading to hyperphosphatemia.
• Here’s a more detailed breakdown:
• 1. **Dietary Phosphate Binding:** When you consume food, it contains phosphate. AUVELIA, taken with meals, releases ferric ions (Fe3+) in the stomach. These ferric ions have a high affinity for phosphate.
• 2. **Formation of Insoluble Complexes:** The ferric ions bind to the phosphate, forming insoluble ferric phosphate compounds. These compounds are stable and cannot be absorbed by the body.
• 3. **Excretion via Feces:** Because the ferric phosphate complexes are insoluble and non-absorbable, they are excreted from the body in the feces. This prevents the phosphate from entering the bloodstream and contributing to elevated serum phosphorus levels.
• 4. **Reduction of Serum Phosphorus:** By consistently binding to dietary phosphate and facilitating its removal, AUVELIA effectively lowers and maintains serum phosphorus levels within the target range recommended by healthcare professionals for patients with CKD on dialysis.
• The effectiveness of AUVELIA relies on consistent administration with meals. This ensures that the Ferric Citrate is present in the GI tract when phosphate from food is available, maximizing the binding potential.
• In summary, AUVELIA TABLET 10'S helps manage hyperphosphatemia in CKD patients on dialysis by acting as a phosphate binder. It prevents the absorption of dietary phosphate by forming insoluble complexes that are then excreted, thus maintaining healthy serum phosphorus levels. Always take the medication as directed by your healthcare provider to achieve the best results.

Like all medicines, Auvelia can cause side effects, although not everybody gets them.\n\n**Very Common (may affect more than 1 in 10 people):**\n* Diarrhea\n* Discolored feces\n\n**Common (may affect up to 1 in 10 people):**\n* Nausea\n* Constipation\n* Vomiting\n* Abdominal pain\n* Abdominal distension\n* Flatulence\n* Fatigue\n\n**Uncommon (may affect up to 1 in 100 people):**\n* Dyspepsia (indigestion)\n* Toothache\n* Dry mouth\n* Esophagitis (inflammation of the esophagus)\n* Dysphagia (difficulty swallowing)\n* Eructation (belching)\n* Hemorrhoids\n* Gastritis (inflammation of the stomach lining)\n* Colitis (inflammation of the colon)\n* Gastroenteritis (inflammation of the stomach and intestines)\n* Fecal incontinence\n* Melena (black, tarry stools)\n* Rectal hemorrhage\n* Abnormal feces\n* General weakness\n* Edema (swelling due to fluid retention)\n\n**Rare (may affect up to 1 in 1,000 people):**\n* Hematochezia (fresh blood in stool)

• If you miss a dose of Auvelia, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for the missed one.

• Keep AUVELIA TAB 1X10 away from the reach of children and pets.
• Store AUVELIA TAB 1X10 at room temperature.

• Take Auvelia as prescribed by your doctor. Do not change the dosage or stop taking it without consulting them, as this could affect how well it works.
• Take Auvelia with meals. This helps your body absorb the medication better and can also reduce the chance of stomach upset.
• Avoid taking antacids containing calcium, magnesium, or aluminum within 2 hours before or after taking Auvelia. These antacids can interfere with how well Auvelia is absorbed.
• If you miss a dose of Auvelia, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to catch up.
• Store Auvelia tablets at room temperature, away from moisture and heat. Keep the medication in its original container and out of reach of children.
• If you experience side effects like nausea, vomiting, or diarrhea while taking Auvelia, inform your doctor. They may be able to recommend ways to manage these side effects.
• Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, as some medications can interact with Auvelia.
• Maintain a consistent intake of phosphate in your diet as advised by your doctor or dietitian while taking Auvelia. This will help ensure the medication works effectively.
• Regular blood tests are important while taking Auvelia to monitor phosphate levels and adjust the dosage if needed. Attend all scheduled appointments with your doctor and lab.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of taking Auvelia with your doctor before starting treatment.

• Take Auvelia tablets with or immediately after a meal. This helps your body absorb the medication properly and reduces the risk of stomach upset. Avoid taking Auvelia on an empty stomach.