AZADINE 50 INJECTION
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AZADINE 50 INJECTION
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AZADINE 50 INJECTION

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AZADINE 50 INJECTION

By INTAS PHARMACEUTICALS LIMITED

MRP

1995

₹1357

31.98 % OFF

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Product DetailsArrow

About AZADINE 50 INJECTION

  • AZADINE 50 INJECTION is a medication specifically designed for adult patients diagnosed with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) who are not suitable candidates for stem cell transplantation. These conditions affect the bone marrow's ability to produce healthy blood cells.
  • Myelodysplastic Syndrome (MDS) is characterized by the bone marrow's inability to function correctly, leading to a deficiency in the production of healthy and functional blood cells. This can result in various complications and a weakened immune system.
  • Acute Myeloid Leukemia (AML) is an aggressive form of bone marrow cancer. It occurs when the bone marrow releases immature and non-functional blood cells into the bloodstream, disrupting normal blood cell production and potentially leading to life-threatening complications. AZADINE 50 INJECTION helps to manage these conditions when stem cell transplant is not a feasible option, aiming to improve the patient's quality of life and overall prognosis. It works by helping the bone marrow to produce more healthy blood cells.
  • This medication is administered via injection and requires close monitoring by healthcare professionals to manage potential side effects and ensure its effectiveness. Regular blood tests and assessments are crucial to track the patient's response to the treatment and adjust the dosage as needed. Patients should discuss any concerns or questions with their healthcare provider to fully understand the benefits and risks associated with AZADINE 50 INJECTION.

Uses of AZADINE 50 INJECTION

  • Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Hematopoietic stem cell transplant. This treatment provides an alternative for patients when a stem cell transplant is not a viable option.
  • Intermediate-2 and High-risk Myelodysplastic syndrome (MDS). This category includes patients with a higher risk of the disease progressing and transforming into acute leukemia.

Side Effects of AZADINE 50 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Unexpected bleeding, with blood in stool and urine
  • Fever
  • Pneumonia, characterized by chest pain or breathlessness.
  • Allergic reaction with symptoms of swelling of lips, itching or rashes.
  • Seizures, loss of consciousness, severe headache or bleeding in the brain
  • Frequent urination with pain or burning sensation
  • Disturbances in the blood count (RBC, WBC, Platelets)
  • Nausea, vomiting, diarrhea
  • Constipation
  • Tiredness
  • Skin reaction like redness and pain at the site of injection
  • Decreased appetite
  • Dizziness
  • Pain in extremities
  • Joint pain
  • Stomach pain
  • Headache
  • Sore nose and throat
  • Rashes and bruising

Safety Advice for AZADINE 50 INJECTIONArrow

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Pregnancy

UNSAFE

AZADINE 50 INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of AZADINE 50 INJECTIONArrow

  • Always use AZADINE 50 INJECTION under the direct supervision and guidance of a qualified physician. Self-administration is strongly discouraged to ensure your safety and the effectiveness of the medication. Your physician will determine the precise dosage of AZADINE 50 INJECTION based on a comprehensive assessment of your individual needs. This assessment takes into account several factors, including your height, weight, overall health condition, and the specific medical condition being treated. Following your physician's prescribed dosage is crucial for achieving the best possible therapeutic outcome.
  • AZADINE 50 INJECTION is administered via a subcutaneous injection, meaning it is injected under the skin. The preferred injection sites are the thigh, stomach (abdomen), or upper arm. Your physician or a trained healthcare professional will administer the injection, ensuring proper technique and hygiene. They will also rotate injection sites to minimize the risk of skin irritation or other localized reactions. If you have any concerns or questions regarding the injection procedure or the choice of injection site, please do not hesitate to discuss them with your physician or healthcare provider.
  • It is important to adhere strictly to the prescribed dosage and administration schedule provided by your doctor. Do not attempt to adjust the dosage or frequency of injections without consulting your doctor, as this may lead to adverse effects or reduce the effectiveness of the medication. Regular follow-up appointments with your doctor are essential to monitor your progress, assess the effectiveness of AZADINE 50 INJECTION, and make any necessary adjustments to your treatment plan.

How to store AZADINE 50 INJECTION?Arrow

  • Keep AZADINE 50MG INJ away from the reach of children and pets.
  • Store AZADINE 50MG INJ at room temperature.

Benefits of AZADINE 50 INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the uncontrolled growth of tumor cells often stems from a process called transcriptional repression. This occurs when genes that normally regulate cell growth and differentiation are silenced due to hypermethylation of DNA.
  • DNA hypermethylation essentially adds chemical tags to DNA, making it difficult for the cell's machinery to access and read the genetic code. Transcriptional repression is a crucial mechanism, involving proteins that directly or indirectly attach to DNA.
  • These proteins interfere with the transcription process, which is the copying of a specific gene or a set of genes into RNA. By preventing proper gene expression, these proteins can disrupt normal cellular functions and contribute to the development of cancer.
  • AZADINE 50 INJECTION works by becoming active within the cell and binding to both RNA and DNA. This interaction disrupts the normal activity of these molecules, particularly in rapidly dividing cells. This disruption leads to a toxic effect specifically targeting cancer cells, inhibiting their growth and proliferation.

How to use AZADINE 50 INJECTIONArrow

  • AZADINE 50 INJECTION should only be administered under the direct supervision of a qualified physician or healthcare professional. This ensures that the injection is given safely and that any potential side effects can be promptly managed.
  • The appropriate dosage of AZADINE 50 INJECTION will be determined by your physician based on several factors, including your individual height, weight, overall health condition, and the specific medical condition being treated. It is crucial to adhere to the prescribed dosage to achieve the desired therapeutic effect.
  • AZADINE 50 INJECTION is typically administered via subcutaneous injection, which means it is injected under the skin. Common injection sites include the thigh, stomach (abdomen), or upper arm. Your physician or nurse will instruct you on the correct injection technique and the most suitable injection site for your specific needs.
  • Prior to each injection, it is essential to inspect the AZADINE 50 INJECTION solution for any particulate matter or discoloration. If the solution appears cloudy or contains particles, do not use it. Use a new vial. Always use a sterile needle and syringe for each injection to prevent infection.
  • Follow your doctor's instructions carefully regarding the frequency and timing of your AZADINE 50 INJECTION doses. Do not skip doses or alter the dosage without consulting your physician. Consistent adherence to the prescribed treatment plan is essential for optimal results.

FAQs

How to use AZADINE 50 INJECTION?Arrow

Take AZADINE 50 INJECTION only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. AZADINE 50 INJECTION is administered under the skin of your thigh, stomach or upper arm.

Does AZADINE 50 INJECTION cause hair loss?Arrow

No, AZADINE 50 INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZADINE 50 INJECTION work?Arrow

AZADINE 50 INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Is AZADINE 50 INJECTION chemotherapy?Arrow

Yes. AZADINE 50 INJECTION is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of AZADINE 50 INJECTION?Arrow

The common side effects of AZADINE 50 INJECTION are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

Is it safe to drive after taking an AZADINE 50 INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking AZADINE 50 INJECTION.

NULL interaction of AZADINE 50 INJECTION with other drungsArrow

There are no known interactions of AZADINE 50 INJECTION with other drugs.

What precautions should I take while taking AZADINE 50 INJECTION?Arrow

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects on the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach, or upper arm.

What molecule/combination is used for making AZADINE 50 INJECTION?Arrow

AZADINE 50 INJECTION is made from Azacitidine.

For which ailments/diseases/conditions AZADINE 50 INJECTION is prescribed?Arrow

AZADINE 50 INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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Generic medicines at reasonable rates.

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Reviewed on 22-04-2024

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Excellent 👍👍👍

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Reviewed on 26-11-2022

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(5/5)

So good it's give information with medicine

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(Translated by Google) This is the right medkart for generics. (Original) Generic ke liye ye sahi hai medkart

Pravas Ranjan Acharya

Reviewed on 24-05-2023

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(2/5)


Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

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India

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AZADINE 50 INJECTION

AZADINE 50 INJECTION

MRP

1995

₹1357

31.98 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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