AZADINE 50 INJECTION

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• In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the uncontrolled growth of tumor cells often stems from a process called transcriptional repression. This occurs when genes that normally regulate cell growth and differentiation are silenced due to hypermethylation of DNA.
• DNA hypermethylation essentially adds chemical tags to DNA, making it difficult for the cell's machinery to access and read the genetic code. Transcriptional repression is a crucial mechanism, involving proteins that directly or indirectly attach to DNA.
• These proteins interfere with the transcription process, which is the copying of a specific gene or a set of genes into RNA. By preventing proper gene expression, these proteins can disrupt normal cellular functions and contribute to the development of cancer.
• AZADINE 50 INJECTION works by becoming active within the cell and binding to both RNA and DNA. This interaction disrupts the normal activity of these molecules, particularly in rapidly dividing cells. This disruption leads to a toxic effect specifically targeting cancer cells, inhibiting their growth and proliferation.

• AZADINE 50 INJECTION should only be administered under the direct supervision of a qualified physician or healthcare professional. This ensures that the injection is given safely and that any potential side effects can be promptly managed.
• The appropriate dosage of AZADINE 50 INJECTION will be determined by your physician based on several factors, including your individual height, weight, overall health condition, and the specific medical condition being treated. It is crucial to adhere to the prescribed dosage to achieve the desired therapeutic effect.
• AZADINE 50 INJECTION is typically administered via subcutaneous injection, which means it is injected under the skin. Common injection sites include the thigh, stomach (abdomen), or upper arm. Your physician or nurse will instruct you on the correct injection technique and the most suitable injection site for your specific needs.
• Prior to each injection, it is essential to inspect the AZADINE 50 INJECTION solution for any particulate matter or discoloration. If the solution appears cloudy or contains particles, do not use it. Use a new vial. Always use a sterile needle and syringe for each injection to prevent infection.
• Follow your doctor's instructions carefully regarding the frequency and timing of your AZADINE 50 INJECTION doses. Do not skip doses or alter the dosage without consulting your physician. Consistent adherence to the prescribed treatment plan is essential for optimal results.