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BENZZ 180 INJECTION

Name: BENZZ 180 INJECTION
Brand: INTAS PHARMACEUTICALS LIMITED
Price: 3705 INR
Availability: InStock

BENZZ 180 INJECTION

By INTAS PHARMACEUTICALS LIMITED

MRP

₹

4478.33

₹3705

17.27 % OFF

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Composition

BENDAMUSTINE 180 MG

Product Details

About BENZZ 180 INJECTION

BENZZ 180 INJECTION contains the active ingredient Bendamustine and belongs to the class of antineoplastic drugs known as alkylating agents. It plays a crucial role in preventing and treating various cancers, including chronic lymphocytic leukaemia (a cancer affecting the blood and bone marrow), non-Hodgkin’s lymphomas (cancers originating in the lymph system, a vital part of the immune system), and multiple myelomas (a cancer of plasma cells, a type of white blood cell responsible for producing antibodies).
Common side effects associated with this medication may include headache, insomnia, fatigue, loss of appetite, and skin rashes. More serious side effects can occur, such as bone marrow suppression (a decrease in the production of blood cells), tumor lysis syndrome (a condition caused by the rapid breakdown of cancer cells), and hepatotoxicity (liver damage). It's crucial to inform your healthcare provider if these side effects become bothersome or persist for an extended period. BENZZ 180 INJECTION is frequently used in combination with rituximab, an immunotherapy drug, to treat specific subtypes of non-Hodgkin's lymphoma, like follicular lymphoma and mantle cell lymphoma. Patients should also be aware of a potential increased risk of developing certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. Immediate consultation with a doctor is advised for further guidance and monitoring.
Treatment with BENZZ 180 INJECTION should not be initiated if your white blood cell (leukocyte) count falls below established levels. Your doctor will regularly monitor these values. This medicine is contraindicated if you have a known allergy to Bendamustine. If you are a man planning to father a child, it is essential to discuss the treatment with your physician, as BENZZ 180 INJECTION may reduce sperm production in men. The drug is typically administered as an intravenous infusion over a period of 30 to 60 minutes, usually once every three to four weeks. Before starting BENZZ 180 INJECTION, inform your physician about all medications you are currently taking, including herbal remedies and supplements, to avoid potential drug interactions.

Uses of BENZZ 180 INJECTION

Chronic lymphocytic leukemia, a type of cancer that affects the blood and bone marrow, characterized by the gradual increase of abnormal lymphocytes.
Non-Hodgkin’s lymphomas, which are a diverse group of blood cancers that develop from lymphocytes, can manifest in various forms and locations within the body.
Multiple myeloma, a cancer of plasma cells, which are a type of white blood cell responsible for producing antibodies, leading to various complications.

Side Effects of BENZZ 180 INJECTION

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them.

Severe allergic reactions
Bone marrow suppression
Abnormal liver function
Tumor lysis syndrome
Infection, fever
Low blood cell count
Headache, dizziness
Nausea, vomiting
Increased blood level of creatinine and urea (chemical waste products)
Mucosal inflammation, sore mouth
Insomnia, fatigue
Hair loss, itching, rash
Diarrhea, constipation
Missed periods
Dehydration, loss of appetite
Low or high blood pressure

Safety Advice for BENZZ 180 INJECTION

Pregnancy

UNSAFE

BENZZ 180 INJECTION is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of BENZZ 180 INJECTION

BENZZ 180 INJECTION will be administered by a qualified healthcare professional in a hospital environment, ensuring your safety and well-being throughout the process. The medication is delivered intravenously, directly into a vein located in your arm or hand, allowing for efficient absorption. It is crucial that you do not attempt to self-administer this medicine under any circumstances.
Your doctor will determine the precise dosage of BENZZ 180 INJECTION based on a comprehensive assessment of your specific medical condition, considering factors such as the severity of your illness, your overall health, and any other medications you may be taking. This personalized approach ensures that you receive the optimal therapeutic benefit.
Typically, BENZZ 180 INJECTION is administered approximately 30 minutes prior to receiving chemotherapy or immediately before undergoing anesthesia for surgery. This timing allows the medication to effectively prepare your body for the subsequent treatment.
During the infusion process, you will be carefully monitored for any potential side effects or adverse reactions to the medication. The healthcare team will closely observe your vital signs and overall condition to ensure your comfort and safety. The infusion process can extend over several hours, and you may require multiple infusions administered over a period of weeks, depending on your treatment plan.

How to store BENZZ 180 INJECTION?

Keep BENZZ 180MG INJ away from the reach of children and pets.
Store BENZZ 180MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of BENZZ 180 INJECTION

BENZZ 180 INJECTION is a powerful medication classified as an alkylating agent, meaning it directly interferes with the DNA of cancer cells. This interference works through several mechanisms to ultimately halt cancer growth and spread. The drug forms strong, covalent bonds with the DNA molecules within cancer cells. This binding process disrupts the DNA's structure and function, preventing it from replicating properly.
Furthermore, BENZZ 180 INJECTION inhibits the enzymes responsible for repairing damaged DNA. Cancer cells, like all cells, have natural repair mechanisms to correct errors in their DNA. By blocking these repair pathways, the drug ensures that the DNA damage it causes is irreparable, pushing the cancer cell towards programmed cell death.
Finally, BENZZ 180 INJECTION effectively blocks the cell cycle progression. The cell cycle is the series of steps a cell goes through as it grows and divides. By halting this cycle, the drug prevents cancer cells from multiplying uncontrollably, thus controlling tumor growth. In essence, BENZZ 180 INJECTION is a cytotoxic drug, meaning it is toxic to cells. It selectively targets and kills cancer cells by disrupting their DNA and cell cycle, making it a valuable tool in cancer treatment.

How to use BENZZ 180 INJECTION

BENZZ 180 INJECTION will be administered to you by a qualified healthcare professional in a hospital setting. This medication is given intravenously, directly into a vein located in your arm or hand. It is crucial that you do not attempt to self-administer this medicine. The precise dosage of BENZZ 180 INJECTION will be determined by your doctor, taking into consideration your specific medical condition, its severity, and other relevant factors. Your doctor will tailor the dosage to best suit your individual needs.
Typically, BENZZ 180 INJECTION is administered approximately 30 minutes before you receive your anti-cancer medicine (chemotherapy) or immediately preceding the administration of anaesthesia for a surgical procedure. This timing is important to ensure the medication works effectively in conjunction with your other treatments.
Throughout the infusion process, you will be carefully monitored by healthcare staff for any potential side effects or adverse reactions to the medication. This close monitoring allows for the prompt management of any issues that may arise. The infusion process can take several hours to complete, and depending on your treatment plan, you may need to receive multiple infusions over the course of several weeks. Your doctor will determine the appropriate duration and frequency of infusions based on your individual circumstances.
It is important to openly communicate with your healthcare provider about any concerns or questions you may have regarding the administration or potential effects of BENZZ 180 INJECTION. They are best equipped to provide you with personalized information and support throughout your treatment journey.

FAQs

What is BENZZ 180 INJECTION used for?

BENZZ 180 INJECTION is a chemotherapy drug used to treat various types of cancers, including non-Hodgkin's lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.

How will I receive BENZZ 180 INJECTION?

BENZZ 180 INJECTION is administered into a vein as a short-term infusion over 30 – 60 minutes.

How does BENZZ 180 INJECTION work to treat cancer?

BENZZ 180 INJECTION works by damaging the DNA in cancer cells, preventing them from multiplying and spreading.

Can BENZZ 180 INJECTION be used in combination with other drugs?

Yes, BENZZ 180 INJECTION is often used in combination with other chemotherapy drugs to improve treatment outcomes.

Whether BENZZ 180 INJECTION is safe to use during pregnancy?

BENZZ 180 INJECTION is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.

Who should not take BENZZ 180 INJECTION?

BENZZ 180 INJECTION should not be taken by individuals who are allergic to it or its ingredients.

Does BENZZ 180 INJECTION interact with other drugs?

There are no known significant interactions of BENZZ 180 INJECTION with other drugs.

What precautions should I take during treatment with BENZZ 180 INJECTION?

BENZZ 180 INJECTION can cause harm to a developing fetus or nursing baby, so it is important to discuss contraception options and the need to avoid breastfeeding during treatment. This drug causes fatigue, so encourage the patient to take enough rest and self-care during treatment. This injection increases the risk of bleeding and bruising, so it is important to be careful when using sharp objects or participating in activities that may result in injury.

What molecule is BENZZ 180 INJECTION made from?

BENDAMUSTINE is the molecule used for making BENZZ 180 INJECTION.

For what ailments/diseases/conditions is BENZZ 180 INJECTION prescribed?

BENZZ 180 INJECTION is prescribed for Oncology ailments/diseases/conditions.

References

Zentiva Pharma UK Limited, Electronic medicines compendium (emc)

Teva Pharmaceuticals USA, Inc, US Food and Drug Administration

Bendamustine 25mg how to store Bendamustine Powder

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Quick service, getting discounts on medicines on regular basis

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Reviewed on 12-02-2024

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Reviewed on 03-02-2024

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Reviewed on 11-03-2024

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Reviewed on 16-01-2024

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Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

Country of Origin -

India

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BENZZ 180 INJECTION

BENZZ 180 INJECTION

Product Details

About BENZZ 180 INJECTION

Uses of BENZZ 180 INJECTION

Side Effects of BENZZ 180 INJECTION

Safety Advice for BENZZ 180 INJECTION

Dosage of BENZZ 180 INJECTION

How to store BENZZ 180 INJECTION?

Benefits of BENZZ 180 INJECTION

How to use BENZZ 180 INJECTION