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BESPONSA 1MG/VIAL INJECTION
By PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED
MRP
₹
330000
₹280500
15 % OFF
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Composition
Product Details
About BESPONSA 1MG/VIAL INJECTION
- BESPONSA 1MG/VIAL INJECTION contains the active ingredient Inotuzumab ozogamicin. It's a medicine used to fight cancer, specifically a type called acute lymphoblastic leukemia (ALL) in adults. This treatment is typically given when other treatments haven't worked well enough or the cancer has returned.
- Acute lymphoblastic leukemia (ALL) is a blood cancer. It happens when the bone marrow, which usually makes healthy blood cells, starts making too many young, abnormal white blood cells. These abnormal cells build up, crowding out the healthy ones.
- You should NOT receive BESPONSA 1MG/VIAL INJECTION if you are allergic to Inotuzumab ozogamicin or any other ingredients in this medicine. It's also not suitable if you have a history of certain serious liver problems, such as veno-occlusive disease (a blockage in liver blood vessels), cirrhosis (severe scarring), nodular regenerative hyperplasia (changes linked to liver portal hypertension), active hepatitis (liver inflammation), or blood clots in the liver. This medicine is generally not recommended for children and teenagers.
- Before starting treatment with BESPONSA 1MG/VIAL INJECTION, tell your doctor about all your medical conditions. Mention if you have symptoms of tumor lysis syndrome (a reaction when cancer cells break down), low blood cell counts (like low neutrophils which help fight infection), high levels of certain enzymes like amylase or lipase, or a history of an irregular heartbeat (called QT interval prolongation). Your doctor will monitor you closely for these issues during treatment.
- It is very important to tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Women must use effective birth control during treatment and for at least 8 months afterwards. Men must use effective birth control during treatment and for at least 5 months afterwards. Discuss any fertility concerns with your healthcare team. Regular blood tests will be done to check your blood counts, liver function, and heart rhythm (QT interval) to ensure the treatment is safe for you.
Side Effects of BESPONSA 1MG/VIAL INJECTION
Side effects are unwanted effects from medicine. While all medicines can cause side effects, not everyone will experience them.
Safety Advice for BESPONSA 1MG/VIAL INJECTION
Alcohol
Consult a DoctorIt is unknown whether it is safe to consume alcohol with BESPONSA 1MG/VIAL INJECTION as this medicine makes you feel drowsy. Please consult your doctor for more information.
BreastFeeding
UnsafeIt is unsafe to take BESPONSA 1MG/VIAL INJECTION while breastfeeding. Before starting the treatment, notify your doctor if you are breastfeeding. Do not breastfeed during and at least after the two months of the last dose.
Driving
UnsafeIt is unsafe to drive while taking BESPONSA 1MG/VIAL INJECTION because this medicine might make you tired. So, avoid driving and operating machinery during this treatment.
Liver Function
Consult a DoctorInform your physician about any underlying liver disorders before taking BESPONSA 1MG/VIAL INJECTION, as this medication should be used cautiously in liver disease patients. Consult your physician before taking this medicine.
Lungs
Consult a DoctorIt is unknown whether BESPONSA 1MG/VIAL INJECTION is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Pregnancy
UnsafeYour doctor will prescribe BESPONSA 1MG/VIAL INJECTION only if needed, as this medicine might cause harm to the unborn baby. So notify your doctor if you are pregnant or planning to get pregnant before starting the treatment. It is advised for women to use contraception during and after the treatment for at least eight months.
Dosage of BESPONSA 1MG/VIAL INJECTION
- BESPONSA 1MG/VIAL INJECTION must *only* be given by a qualified healthcare professional, such as a trained doctor or nurse. It is crucial *not* to attempt to give yourself this medicine. The exact amount of BESPONSA 1MG/VIAL INJECTION you receive, and how long your treatment lasts, will be carefully determined by your doctor. This decision is based on important factors like how serious your disease is, your overall health, your response to the medication, and any other treatments you are receiving.
- BESPONSA is administered as an intravenous (IV) infusion, meaning it is given directly into your vein, usually over a set period. This infusion typically takes place in a clinical setting, like a hospital or a doctor's office.
- Throughout your treatment, and particularly during and after the infusion, you will be closely watched by medical staff. This monitoring is essential to check for any potential or unwanted side effects and ensure your treatment is proceeding safely and effectively. Always follow your doctor's instructions precisely regarding your BESPONSA 1MG/VIAL INJECTION treatment schedule.
How to store BESPONSA 1MG/VIAL INJECTION?
- Keep BESPONSA 1MG INJ away from the reach of children and pets.
- Store BESPONSA 1MG INJ in a refrigerator (2 - 8°C). Do not freeze.
Benefits of BESPONSA 1MG/VIAL INJECTION
- Inotuzumab ozogamicin is a powerful medicine designed to fight a type of blood cancer called Acute Lymphoblastic Leukemia (ALL). It works by specifically finding and attaching to a protein known as CD22, which is very often found on the surface of ALL cancer cells. Think of CD22 as a unique marker on these cancer cells. Once Inotuzumab ozogamicin latches onto the CD22 protein on the surface of an ALL cell, the cancer cell "takes in" the medicine. This is like the cancer cell absorbing the drug from its surface. The drug then releases a potent substance inside the cell. This substance, the ozogamicin part, travels to the cell's nucleus, which contains its DNA. It then disrupts and damages the DNA, which is essential for the cell's survival and ability to multiply. By damaging the DNA, the medicine prevents the cancer cells from growing and dividing. This severe damage ultimately triggers the cancer cell's self-destruction process, leading to its death. This targeted approach means the medicine primarily affects cancer cells with the CD22 marker, helping to spare healthy cells that do not have this protein on their surface.
How to use BESPONSA 1MG/VIAL INJECTION
- Only a qualified healthcare professional, such as a doctor or nurse, is authorized to administer BESPONSA 1MG/VIAL INJECTION. It is absolutely crucial that you do not attempt to inject this medicine yourself at home. Your treating physician will determine the appropriate dose and the total duration of your treatment course. This decision is carefully made based on several factors, including the specific type and severity of your disease, your overall health status, and how you respond to the initial treatment. The medication will be delivered directly into your bloodstream through a vein using an intravenous infusion, commonly known as a drip. During the infusion and for a period afterward, you will be under careful observation by the healthcare team. This close monitoring is essential to detect and promptly manage any potential side effects or adverse reactions that might occur. Administering this potent medicine requires specialized expertise to ensure it is given safely and effectively. Therefore, rely completely on your medical team for its administration and follow their instructions precisely.
FAQs
Why is liver enzyme getting elevated during treatment with BESPONSA 1MG/VIAL INJECTION?
The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function.
Do we have to use contraception even after the treatment with BESPONSA 1MG/VIAL INJECTION?
Yes, it is advised to use effective contraception even after the last dose of BESPONSA 1MG/VIAL INJECTION; 8 months for women and five months for men.
What should I inform the doctor about before starting the BESPONSA 1MG/VIAL INJECTION?
Inform about underlying medical conditions, especially the history of blood clots and liver-related conditions, before starting BESPONSA 1MG/VIAL INJECTION.
Can I use BESPONSA 1MG/VIAL INJECTION in children?
No, Only limited information is available about BESPONSA 1MG/VIAL INJECTION usage in children. So it is advised not to use it in children. Talk to your doctor for more information.
Do we have to take any tests during BESPONSA 1MG/VIAL INJECTION treatment?
Yes, your physician might regularly take blood tests to monitor your blood count and liver enzymes. Additionally, an electrocardiogram will monitor your electrolyte during the treatment with BESPONSA 1MG/VIAL INJECTION.
What should I know about drug interactions with BESPONSA 1MG/VIAL INJECTION?
Please inform your doctor about all medications you are taking, including prescription, over-the-counter drugs, vitamins, and herbal supplements, as they may interact with BESPONSA 1MG/VIAL INJECTION. Your doctor will determine if any adjustments are needed.
What important advice should I follow while taking BESPONSA 1MG/VIAL INJECTION?
Dose adjustments will be made based on the response to the treatment. Pre-medicine will be given to reduce the infusion reactions, keep hydrated, and prevent tumour lysis syndrome and other side effects. There is limited information on the safety of BESPONSA 1MG/VIAL INJECTION in renal failure patients; inform your physician if you have kidney disease. Notify your doctor if you experience any side effect symptoms, as your doctor may change the dosage of this medicine or give additional medicine to reduce the effect of the side effects. Men should use effective contraception during and after the last dose of the treatment.
What is the main ingredient in BESPONSA 1MG/VIAL INJECTION?
The main ingredient in BESPONSA 1MG/VIAL INJECTION is INOTUZUMAB OZOGAMICIN.
What condition is BESPONSA 1MG/VIAL INJECTION prescribed for?
BESPONSA 1MG/VIAL INJECTION is prescribed for Anti Cancer conditions.
References
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Reviewed on 30-03-2024
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Marketer / Manufacturer Details
PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED
Country of Origin -
India
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