bexol 2mg tablet 10's
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BEXOL 2MG TABLET 10'S

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BEXOL 2MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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14.6

₹12.41

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Product DetailsArrow

Content Reviewed By:

Dr. Rajesh Sharma

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About BEXOL 2MG TABLET 10'S

  • Bexol tablet is a branded formulation of trihexyphenidyl (also known as benzhexol), an anticholinergic medicine primarily used in the management of Parkinson’s disease and certain drug‑induced movement disorders. It works by blocking muscarinic acetylcholine receptors in the central nervous system, helping to restore the balance between acetylcholine and dopamine in specific brain regions involved in movement control. This leads to improvement in symptoms such as muscle stiffness, rigidity, tremor, and slowed movements. Bexol tablets are often used as adjunctive therapy along with levodopa or other antiparkinsonian medicines, particularly in patients whose symptoms include prominent tremor or dystonia. They may also be prescribed to treat extrapyramidal symptoms (EPS) caused by antipsychotic medicines, such as acute dystonia, parkinsonism, or akathisia, when clinically appropriate. The uses of Bexol tablet are individualized and depend on the patient’s age, underlying condition, and concurrent medications. In Parkinson’s disease, it may be considered in younger patients or those who cannot tolerate other therapies, but it is generally used with caution in older adults because of a higher risk of confusion, memory problems, and other anticholinergic side effects. In drug‑induced movement disorders, Bexol can help relieve involuntary muscle contractions, neck stiffness, oculogyric crisis, and restlessness. It is not a cure for Parkinson’s disease or psychiatric conditions; rather, it provides symptomatic relief and must be used under close medical supervision. Common side effects of Bexol include dry mouth, blurred vision, constipation, nausea, dizziness, and urinary difficulty. Because it reduces sweating, there is a risk of overheating and heatstroke, especially in hot weather or during vigorous exercise. It can also worsen glaucoma, urinary retention, and certain heart conditions. Cognitive effects such as confusion, agitation, or hallucinations may occur, particularly in elderly patients or those with pre‑existing cognitive impairment. Abrupt discontinuation should be avoided, as it may lead to worsening of Parkinsonian symptoms or rebound movement disorders. The dose, treatment duration, and any changes in therapy must always be determined by a qualified physician, and patients should not adjust or stop the medicine on their own. Bexol tablet should be used cautiously in people with liver or kidney impairment, prostate enlargement, bowel obstruction, or a history of seizures. It may interact with other anticholinergic drugs, antipsychotics, antidepressants, antihistamines, and certain antiarrhythmics, potentially increasing side effects such as dry mouth, constipation, confusion, or rapid heartbeat. Regular follow‑up with the prescribing doctor is important to monitor symptom control, side effects, and the need for dose adjustments. Patients should be advised to report any sudden vision changes, severe constipation, difficulty passing urine, chest pain, confusion, or hallucinations immediately. As with all prescription medicines, Bexol tablets should only be taken on medical advice and according to the instructions provided by the healthcare professional and the product’s approved prescribing information.

Uses of BEXOL 2MG TABLET 10'S

  • Treatment of Parkinson's disease
  • Treatment of drug-induced parkinsonism
  • Treatment of muscle stiffness
  • Treatment of tremors
  • Treatment of abnormal muscle movements
  • Treatment of excessive salivation

How BEXOL 2MG TABLET 10'S Works

  • BEXOL 2MG TABLET 10'S contains Trihexyphenidyl, an anticholinergic medication primarily used to treat the symptoms of Parkinson's disease and drug-induced movement disorders (extrapyramidal symptoms). Parkinson's disease is a progressive neurological disorder that affects movement, causing tremors, rigidity, slow movement (bradykinesia), and postural instability. These symptoms arise due to an imbalance of neurotransmitters, specifically a deficiency of dopamine and an excess of acetylcholine, in the brain.
  • Trihexyphenidyl works by blocking the action of acetylcholine, a neurotransmitter that transmits signals in the brain. In Parkinson's disease, the reduction of dopamine leads to an overactivity of acetylcholine, contributing to the characteristic motor symptoms. By blocking acetylcholine, Trihexyphenidyl helps to restore the balance between dopamine and acetylcholine, thus reducing tremors, rigidity, and improving muscle control. It specifically targets muscarinic acetylcholine receptors, which are primarily involved in the transmission of signals related to muscle movement.
  • In simpler terms, think of the brain's motor control system as having two main pathways, one using dopamine and the other using acetylcholine. In Parkinson's, the dopamine pathway is weakened, causing the acetylcholine pathway to become overactive and leading to uncontrolled muscle movements. BEXOL 2MG TABLET 10'S steps in to calm down the overactive acetylcholine pathway, helping to restore smoother, more coordinated movement.
  • Furthermore, BEXOL is effective in managing drug-induced extrapyramidal symptoms, which are movement disorders caused by certain medications, especially antipsychotics. These symptoms can include dystonia (sustained muscle contractions), akathisia (restlessness), and parkinsonism (Parkinson's-like symptoms). Trihexyphenidyl helps alleviate these symptoms by counteracting the acetylcholine-mediated effects induced by these medications. By reducing the excessive acetylcholine activity, BEXOL helps in normalizing muscle tone and reducing involuntary movements.
  • The precise mechanism involves competitive antagonism of acetylcholine at muscarinic receptor sites in the brain and peripheral nervous system. This antagonism reduces the excitability of neurons, leading to a decrease in the nerve impulses that cause muscle rigidity and tremors. The impact is most notable in the basal ganglia, a brain region crucial for motor control. This overall action leads to improvement in muscle control, reduction in stiffness, and diminished tremors, thereby enhancing the patient's ability to perform daily activities more comfortably.

Side Effects of BEXOL 2MG TABLET 10'SArrow

Common side effects of Bexol 2mg Tablet may include dry mouth, blurred vision, constipation, nausea, vomiting, dizziness, lightheadedness, drowsiness, weakness, and decreased sweating. Less common but potentially serious side effects can include rapid heartbeat, difficulty urinating, eye pain, mental/mood changes (such as confusion, hallucinations, nervousness), and muscle stiffness/spasms. In rare cases, allergic reactions like rash, itching, swelling, severe dizziness, or trouble breathing may occur. Consult your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for BEXOL 2MG TABLET 10'SArrow

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Other medical conditions

Special precautions

Bexol tablet can worsen certain pre‑existing conditions such as narrow‑angle glaucoma, urinary retention, severe prostate enlargement, bowel obstruction, and myasthenia gravis, and is generally contraindicated or used only under strict specialist supervision in these settings.

Dosage of BEXOL 2MG TABLET 10'SArrow

  • The dosage of 'BEXOL 2MG TABLET 10'S' is highly individualized and depends on the severity of your condition, your response to treatment, and other factors as determined by your doctor. It's crucial to adhere strictly to the prescribed dosage and schedule. Typically, the initial dose for adults ranges from 1 to 2 mg per day, administered in divided doses. Your doctor may gradually increase the dosage as needed, usually by 0.5 mg every 5 to 7 days, until the optimal therapeutic effect is achieved without causing intolerable side effects. The maintenance dose commonly falls between 3 mg and 6 mg daily, but some individuals may require higher doses. For postencephalitic parkinsonism, larger doses might be necessary.
  • It's important to note that abrupt cessation of 'BEXOL 2MG TABLET 10'S' can lead to withdrawal symptoms or a worsening of your condition. If discontinuing the medication is necessary, your doctor will gradually reduce the dosage to minimize any adverse effects. Always take 'BEXOL 2MG TABLET 10'S' with or after food to minimize gastric irritation. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Remember, consistent adherence to your doctor's instructions is paramount for achieving the best possible outcome. Regular follow-up appointments are crucial to monitor your progress and adjust the dosage accordingly. Self-medication or altering the dosage without consulting your doctor can be harmful. Take 'BEXOL 2MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of BEXOL 2MG TABLET 10'S?Arrow

  • If you miss a dose of Bexol 2mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store BEXOL 2MG TABLET 10'S?Arrow

  • Keep BEXOL 2MG TAB 1X10 away from the reach of children and pets.
  • Store BEXOL 2MG TAB 1X10 at room temperature.

Benefits of BEXOL 2MG TABLET 10'SArrow

  • BEXOL 2MG TABLET 10'S is primarily prescribed to manage and alleviate the symptoms of Parkinson's disease. It helps to reduce tremors, muscle stiffness, and rigidity, allowing patients to perform daily activities with greater ease and comfort. By improving motor control, BEXOL enhances the overall quality of life for individuals living with Parkinson's.
  • The medication is also effective in controlling drug-induced parkinsonism. Certain medications, particularly antipsychotics, can cause Parkinson's-like symptoms as a side effect. BEXOL helps to counteract these effects, reducing tremors, rigidity, and other motor disturbances caused by these drugs. This allows patients to continue their necessary treatments without the debilitating side effects.
  • BEXOL can significantly improve muscle control and coordination. Patients often experience difficulties with movements such as walking, writing, and speaking. BEXOL helps to regulate muscle activity, making movements smoother and more coordinated. This improvement can lead to increased independence and a greater ability to participate in daily tasks.
  • Another key benefit of BEXOL is its ability to reduce excessive salivation, a common symptom in Parkinson's disease. Excessive drooling can be embarrassing and uncomfortable for patients. BEXOL helps to control saliva production, providing relief from this bothersome symptom and improving social confidence.
  • BEXOL also addresses other motor symptoms associated with Parkinson's disease, such as bradykinesia (slowness of movement) and postural instability (difficulty maintaining balance). By improving these symptoms, BEXOL helps patients maintain their mobility and reduce their risk of falls, contributing to a safer and more active lifestyle.
  • Furthermore, BEXOL can improve sleep quality in patients with Parkinson's disease. Motor symptoms often disrupt sleep, leading to fatigue and reduced daytime alertness. By controlling these symptoms, BEXOL helps patients achieve more restful sleep, improving their overall well-being.
  • The medication is often used in conjunction with other Parkinson's medications, such as levodopa. BEXOL can enhance the effectiveness of these other medications, allowing for lower doses and potentially reducing the risk of side effects associated with higher doses of other drugs. This combination therapy can provide more comprehensive symptom control and improve the overall management of Parkinson's disease.
  • BEXOL helps to restore the balance of certain chemicals in the brain, which are disrupted in Parkinson's disease. By modulating neurotransmitter activity, BEXOL can alleviate a wide range of motor and non-motor symptoms, improving overall neurological function and enhancing the patient's ability to function normally.

How to use BEXOL 2MG TABLET 10'SArrow

  • BEXOL 2MG TABLET 10'S is typically taken orally. It's crucial to adhere strictly to your doctor's prescribed dosage and schedule. Never alter the dosage yourself, even if you feel better or worse; always consult your healthcare provider first.
  • Swallow the tablet whole with a full glass of water. Avoid crushing, chewing, or breaking the tablet unless specifically instructed by your doctor. This ensures the medication is released properly and absorbed effectively.
  • The timing of your doses can be important. Your doctor may recommend taking BEXOL 2MG TABLET 10'S at the same time each day to maintain a consistent level of medication in your system. Consistency is key for optimal results.
  • If you miss a dose of BEXOL 2MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • BEXOL 2MG TABLET 10'S can be taken with or without food. If you experience stomach upset, try taking it with food. However, always follow your doctor's recommendations regarding food intake with this medication.
  • During treatment with BEXOL 2MG TABLET 10'S, avoid alcohol consumption as it can increase the risk of side effects. Also, inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential drug interactions.
  • Do not stop taking BEXOL 2MG TABLET 10'S abruptly without consulting your doctor. Sudden discontinuation of the medication can lead to withdrawal symptoms or a worsening of your condition. Your doctor will gradually reduce the dosage if it is necessary to stop the treatment.
  • Store BEXOL 2MG TABLET 10'S at room temperature, away from direct sunlight, heat, and moisture. Keep the medication out of reach of children and pets. Properly dispose of any unused or expired medication according to your local regulations or pharmacy instructions.

Quick Tips for BEXOL 2MG TABLET 10'SArrow

  • Take BEXOL 2MG TABLET 10'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or frequency. This medication is typically taken orally, with or without food. Consistency is key, so try to take it at the same time each day to maintain a steady level of the medication in your system. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.
  • BEXOL 2MG TABLET 10'S can cause side effects such as dry mouth, blurred vision, constipation, and difficulty urinating. Manage dry mouth by sipping water frequently, chewing sugar-free gum, or using sugar-free hard candies. To prevent constipation, increase your fiber intake through diet or consider a stool softener. If blurred vision occurs, avoid activities that require clear vision, such as driving, until your vision clears. Report any persistent or bothersome side effects to your doctor.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting BEXOL 2MG TABLET 10'S. This is crucial because BEXOL 2MG TABLET 10'S can interact with other drugs, potentially affecting how they work or increasing the risk of side effects. Pay special attention to other medications with anticholinergic effects, as combining them can intensify side effects like dry mouth and constipation.
  • BEXOL 2MG TABLET 10'S may impair your ability to perform tasks that require alertness and coordination, such as driving or operating machinery. Avoid these activities until you know how the medication affects you. Be cautious when standing up or changing positions, as BEXOL 2MG TABLET 10'S can cause dizziness or lightheadedness, especially when you first start taking it. Get up slowly to minimize the risk of falls.
  • Store BEXOL 2MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Properly dispose of any unused or expired medication. Do not flush it down the toilet or throw it in the trash. Check with your local pharmacy or waste disposal company for proper disposal instructions. Adhering to these storage guidelines ensures the medication remains effective and safe for use.

Food Interactions with BEXOL 2MG TABLET 10'SArrow

  • BEXOL 2MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at the same time each day to maintain a consistent level of medication in your body. There are no known specific food interactions with BEXOL 2MG TABLET 10'S, but it's generally a good practice to maintain a balanced diet while taking any medication. If you experience any stomach upset, taking it with food might help.

FAQs

What is Bexol 2mg Tablet used for?Arrow

Bexol 2mg Tablet is used to manage symptoms of Parkinson's disease such as tremors, muscle stiffness, and slow movement. It is also used to treat movement disorders caused by certain medications.

How does Bexol 2mg Tablet work?Arrow

Bexol 2mg Tablet works by restoring the balance of certain natural substances (neurotransmitters) in the brain. It helps to improve muscle control and reduce stiffness.

What are the common side effects of Bexol 2mg Tablet?Arrow

Common side effects of Bexol 2mg Tablet include dry mouth, constipation, blurred vision, dizziness, and difficulty urinating.

Can I take Bexol 2mg Tablet with or without food?Arrow

Bexol 2mg Tablet can be taken with or without food, but it is best to take it at the same time each day.

What happens if I miss a dose of Bexol 2mg Tablet?Arrow

If you miss a dose of Bexol 2mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Is it safe to stop taking Bexol 2mg Tablet suddenly?Arrow

Do not stop taking Bexol 2mg Tablet suddenly. Talk to your doctor, who may gradually reduce the dosage to avoid withdrawal symptoms.

How to store Bexol 2mg Tablet?Arrow

Store Bexol 2mg Tablet at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can Bexol 2mg Tablet interact with other medications?Arrow

Yes, Bexol 2mg Tablet can interact with certain other medications, such as antihistamines, antidepressants, and antipsychotics. Tell your doctor about all the medications you are taking.

Is Bexol 2mg Tablet safe during pregnancy?Arrow

The safety of Bexol 2mg Tablet during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

Is Bexol 2mg Tablet safe during breastfeeding?Arrow

It is not known whether Bexol 2mg Tablet passes into breast milk. Consult your doctor before breastfeeding.

Is Bexol 2mg Tablet addictive?Arrow

Bexol 2mg Tablet is not addictive, but it should be taken only as prescribed by your doctor.

What are the symptoms of an overdose of Bexol 2mg Tablet?Arrow

Symptoms of an overdose of Bexol 2mg Tablet may include confusion, agitation, hallucinations, fast heartbeat, and seizures. Seek immediate medical attention if you suspect an overdose.

Is it safe to drink alcohol while taking Bexol 2mg Tablet?Arrow

Drinking alcohol while taking Bexol 2mg Tablet may increase the risk of side effects. Talk to your doctor before drinking alcohol.

What are other brands of Trihexyphenidyl?Arrow

Trihexyphenidyl is available under various brand names. Check with your doctor or pharmacist about the different brands available in your region.

How long does it take for Bexol 2mg Tablet to show benefits?Arrow

It may take a few days or weeks for Bexol 2mg Tablet to show benefits. Continue taking the medication as directed by your doctor, even if you do not see immediate improvement.

What is Bexol tablet used for?Arrow

Bexol tablet, containing trihexyphenidyl (benzhexol), is primarily used to manage symptoms of Parkinson’s disease such as muscle stiffness, rigidity, tremor, and slowed movements. It is also used to treat certain drug‑induced movement disorders (extrapyramidal symptoms) caused by antipsychotic or other medicines, including acute dystonia, parkinsonism, and sometimes akathisia, when considered appropriate by a physician.

How does Bexol tablet work in Parkinson’s disease?Arrow

In Parkinson’s disease there is a relative deficiency of dopamine and an excess of acetylcholine activity in specific brain regions that control movement. Bexol (trihexyphenidyl) blocks muscarinic acetylcholine receptors, reducing cholinergic overactivity and helping to rebalance dopamine and acetylcholine. This mechanism can improve tremor, muscle stiffness, and some other motor symptoms, although it does not stop disease progression.

Can Bexol tablet cure Parkinson’s disease?Arrow

Bexol tablet does not cure Parkinson’s disease. It is a symptomatic treatment that helps control certain motor symptoms, particularly tremor and rigidity. The underlying neurodegenerative process continues, so long‑term management usually involves a combination of medicines, physical therapy, and regular monitoring by a neurologist. Bexol is typically used as an adjunct to other antiparkinsonian drugs rather than as sole therapy in most patients.

Is Bexol tablet used for drug‑induced movement disorders?Arrow

Yes. Bexol tablet is commonly used to treat extrapyramidal symptoms caused by antipsychotic and some other medicines. These may include acute dystonic reactions (such as neck twisting, jaw spasms, or oculogyric crisis), drug‑induced parkinsonism (tremor, rigidity, slowed movements), and in some cases akathisia (a feeling of inner restlessness with an urge to move). The decision to use Bexol for these conditions must be made by a doctor after assessing the risks and benefits and considering adjustment of the causative drug.

Can I take Bexol tablet on my own for tremors?Arrow

You should not start Bexol tablet on your own for tremors or any other symptom. Tremor can have many causes, including essential tremor, anxiety, thyroid disease, medication effects, and Parkinson’s disease. Bexol is specifically indicated for Parkinsonian and certain drug‑induced tremors and carries significant anticholinergic side effects. A doctor must evaluate the cause of your tremor and decide whether Bexol is appropriate, safe, and necessary in your case.

What are the common side effects of Bexol tablet?Arrow

Common side effects of Bexol tablet include dry mouth, blurred vision, constipation, nausea, decreased sweating, dizziness, light‑headedness, and difficulty passing urine. Some people may experience nervousness, confusion, or mild memory problems, especially at higher doses or in older adults. These effects are related to its anticholinergic action. If side effects are troublesome or persistent, you should contact your doctor for review.

Who should avoid or use Bexol tablet with caution?Arrow

Bexol tablet should be avoided or used with great caution in people with narrow‑angle glaucoma, urinary retention, severe prostate enlargement, bowel obstruction, severe ulcerative colitis, myasthenia gravis, or significant cognitive impairment. Caution is also required in elderly patients, and in those with heart disease, arrhythmias, liver or kidney impairment, or a history of seizures. Your doctor will review your medical history and other medicines before prescribing Bexol.

Can Bexol tablet affect my vision or eyes?Arrow

Yes. Bexol can cause blurred vision and difficulty focusing, particularly for near tasks, due to its anticholinergic effect on the eye muscles. It may also increase intraocular pressure and can worsen or precipitate narrow‑angle glaucoma. People with known or suspected glaucoma should inform their doctor before starting Bexol. Any sudden eye pain, redness, halos around lights, or sudden vision changes require urgent medical attention.

Is it safe to stop Bexol tablet suddenly?Arrow

Stopping Bexol tablet abruptly without medical advice is not recommended. Sudden discontinuation can lead to worsening of Parkinsonian symptoms or recurrence of drug‑induced movement disorders. In some cases, abrupt withdrawal may cause rebound effects such as increased rigidity or tremor. If your doctor decides that Bexol should be stopped, the dose is usually reduced gradually while monitoring your symptoms.

Can Bexol tablet be taken with other Parkinson’s medicines?Arrow

Bexol tablet is often used in combination with other Parkinson’s medicines such as levodopa or dopamine agonists. The combination can provide better control of symptoms, especially tremor. However, combining multiple medicines increases the risk of side effects and drug interactions. Your neurologist will determine the appropriate treatment regimen and adjust doses based on your response, age, and tolerance. You should not change or add medicines without consulting your doctor.

Does Bexol tablet cause drowsiness or affect driving?Arrow

Bexol tablet can cause dizziness, blurred vision, and sometimes drowsiness or confusion, which may impair your ability to drive or operate machinery safely. Until you know how the medicine affects you, you should avoid driving, cycling, or performing tasks that require clear vision and full alertness. If you experience persistent visual disturbances, confusion, or significant dizziness, inform your doctor promptly.

References

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DrugBank: Benzatropine

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PubChem: Benzatropine

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National Center for Biotechnology Information (NCBI): 'Anticholinergic burden and cognitive performance in older adults: A systematic review and meta-analysis'

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FDA (Food and Drug Administration): 'Benztropine Mesylate prescribing information'

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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