BISOFIG AM 5MG TABLET 10'S

How BISOFIG AM 5MG TABLET 10'S Works

• BISOFIG AM 5MG TABLET 10'S is a combination medication designed to manage hypertension (high blood pressure) and related cardiovascular conditions. It combines two active ingredients: Bisoprolol and Amlodipine, each working through different mechanisms to achieve a synergistic effect in lowering blood pressure and improving heart health.
• Bisoprolol is a beta-blocker, specifically a beta-1 selective adrenergic blocking agent. It primarily targets beta-1 receptors located in the heart. By blocking these receptors, Bisoprolol reduces the heart rate and the force of heart muscle contractions. This results in a decreased cardiac output, which is the amount of blood the heart pumps per minute. Lowering cardiac output helps to reduce blood pressure. Furthermore, Bisoprolol also decreases the release of renin, an enzyme produced by the kidneys that contributes to vasoconstriction (narrowing of blood vessels) and increased blood volume, further aiding in blood pressure reduction. The selectivity of Bisoprolol for beta-1 receptors minimizes its effect on beta-2 receptors found in the lungs and peripheral blood vessels, reducing the risk of bronchospasm (narrowing of airways) and peripheral vasoconstriction compared to non-selective beta-blockers.
• Amlodipine, on the other hand, is a calcium channel blocker, specifically a dihydropyridine calcium antagonist. It works by inhibiting the influx of calcium ions into vascular smooth muscle cells and cardiac muscle cells. In vascular smooth muscle, this calcium channel blockade leads to vasodilation (relaxation of blood vessels), particularly in the arterioles. This reduces peripheral vascular resistance, the resistance the heart must pump against to circulate blood, thereby lowering blood pressure. In cardiac muscle, Amlodipine's effect is less pronounced but still contributes to reducing the workload on the heart. It also helps to dilate coronary arteries, improving blood flow to the heart muscle itself, which is beneficial in conditions like angina (chest pain).
• The combination of Bisoprolol and Amlodipine in BISOFIG AM 5MG TABLET 10'S provides a comprehensive approach to blood pressure management. Bisoprolol lowers blood pressure by reducing cardiac output and renin release, while Amlodipine lowers blood pressure by reducing peripheral vascular resistance. This dual mechanism of action often results in more effective blood pressure control than either drug used alone. The medication helps to reduce the risk of cardiovascular events such as heart attack, stroke, and kidney problems associated with uncontrolled hypertension. Regular use, as prescribed by a healthcare professional, is crucial for maintaining optimal blood pressure levels and protecting cardiovascular health.

Common side effects of Bisofig AM 5mg Tablet may include: Headache, Dizziness, Fatigue, Sleepiness, Nausea, Abdominal pain, Diarrhea, Constipation, Cold extremities (hands and feet), Muscle cramps, Joint pain, Slow heart rate (bradycardia), Low blood pressure (hypotension), Swelling of ankles/feet (edema). Less common side effects may include: Mood changes, Depression, Shortness of breath (dyspnea), Worsening of asthma, Increased triglycerides, Increased uric acid, Hair loss, Erectile dysfunction, Visual disturbances, Dry eyes, Skin rash, Allergic reactions.

• If you miss a dose of BISOFIG AM 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep BISOFIG AM 5MG TAB 1X10 away from the reach of children and pets.
• Store BISOFIG AM 5MG TAB 1X10 at room temperature.

• **Take consistently:** For optimal results, take BISOFIG AM 5MG TABLET 10'S at the same time each day. Consistency helps maintain a steady level of medication in your bloodstream, maximizing its effectiveness in managing your blood pressure.
• **Monitor blood pressure regularly:** Keep a log of your blood pressure readings at home and share them with your doctor. This helps them assess how well the medication is working and make any necessary adjustments to your treatment plan. Regular monitoring provides valuable insights into your cardiovascular health.
• **Be mindful of potential side effects:** While BISOFIG AM 5MG TABLET 10'S is generally well-tolerated, some individuals may experience side effects like dizziness, headache, or swelling in the ankles. If you notice any persistent or bothersome side effects, consult your doctor for guidance. Do not discontinue the medication without medical advice.
• **Inform your doctor about all medications:** Before starting BISOFIG AM 5MG TABLET 10'S, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medications can interact with bisoprolol and amlodipine, potentially affecting their efficacy or increasing the risk of side effects. A comprehensive medication history ensures safe and effective treatment.
• **Maintain a healthy lifestyle:** BISOFIG AM 5MG TABLET 10'S works best when combined with a healthy lifestyle. This includes eating a balanced diet low in sodium and saturated fats, engaging in regular physical activity, maintaining a healthy weight, and avoiding smoking. These lifestyle modifications can significantly improve your blood pressure control and overall cardiovascular health.

• BISOFIG AM 5MG TABLET 10'S can be taken with or without food. However, it is important to maintain a consistent diet and avoid excessive consumption of high-fat foods, as this may affect the absorption and efficacy of the medication. Consult your doctor or pharmacist for specific dietary advice.