BIXIBAT 5MG TABLET 10'S

How BIXIBAT 5MG TABLET 10'S Works

• BIXIBAT 5MG TABLET 10'S contains Bixibat as its active ingredient, which belongs to a class of medications known as ileal bile acid transporter (IBAT) inhibitors. Bixibat works by reducing the absorption of bile acids in the small intestine. To understand how this benefits patients with certain liver conditions, it's important to understand the role of bile acids.
• Bile acids are produced by the liver and are essential for the digestion and absorption of fats in the small intestine. After they have performed their function, most bile acids are reabsorbed back into the bloodstream in the ileum (the final section of the small intestine) and transported back to the liver. This process is called enterohepatic circulation. In certain liver diseases, such as progressive familial intrahepatic cholestasis (PFIC), the flow of bile from the liver is impaired, leading to a build-up of bile acids in the liver and bloodstream. This build-up causes intense itching (pruritus) and can damage the liver.
• Bixibat inhibits the ileal bile acid transporter (IBAT), the protein responsible for reabsorbing bile acids in the ileum. By blocking IBAT, Bixibat prevents bile acids from being reabsorbed back into the bloodstream. This increases the excretion of bile acids in the feces, reducing the overall level of bile acids in the body. The reduced levels of bile acids in the bloodstream alleviate the symptoms of pruritus and may also reduce liver damage associated with cholestasis. Essentially, Bixibat helps the body get rid of excess bile acids when the liver cannot process them effectively.
• Therefore, BIXIBAT 5MG TABLET 10'S mechanism of action focuses on reducing the reabsorption of bile acids, thereby lowering their levels in the blood. This reduction in bile acid concentration helps to alleviate itching and potentially protect the liver from further damage in patients with specific cholestatic liver diseases.

Common side effects of Bixibat may include: Diarrhea, Abdominal pain, Vomiting, Nausea, Frequent bowel movements, and elevated liver enzymes. Less common but potentially serious side effects can include: Dehydration, Weight loss or poor weight gain (in children), and Fat malabsorption. Allergic reactions like rash, itching or swelling are also possible. Consult your doctor if you experience any persistent or severe side effects.

• If you miss a dose of BIXIBAT 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep BIXIBAT 5MG TAB 1X10 away from the reach of children and pets.
• Store BIXIBAT 5MG TAB 1X10 at room temperature.

• Take Bixibat 5mg Tablet as prescribed by your doctor. It is usually taken once daily, but your doctor may adjust the dosage based on your response and condition. Consistency is key, so try to take it at the same time each day to maintain a steady level in your body, which helps manage pruritus effectively. Never self-adjust the dosage without consulting your doctor.
• Bixibat is prescribed to reduce the itching (pruritus) associated with progressive familial intrahepatic cholestasis (PFIC). It works by preventing the reabsorption of bile acids in the intestines, which helps reduce the amount of bile acids in the blood and alleviates itching. If you're unsure about your diagnosis, consult with your doctor.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting Bixibat. Some medications can interact with Bixibat, potentially affecting its effectiveness or increasing the risk of side effects. It's crucial to provide a complete medication history to your healthcare provider.
• During treatment with Bixibat, your doctor will regularly monitor your liver function. This is important to ensure the medication is working effectively and to detect any potential liver-related issues early on. Attend all scheduled appointments and promptly report any unusual symptoms or changes in your health to your doctor.
• If you experience any side effects, such as diarrhea, abdominal pain, or any other concerning symptoms, contact your doctor immediately. Do not stop taking Bixibat without first discussing it with your healthcare provider, as abruptly stopping the medication may worsen your condition.
• Store Bixibat tablets in a cool, dry place away from direct sunlight and moisture. Keep them out of reach of children and pets. Always check the expiration date before taking the medication and properly dispose of any expired or unused tablets according to local regulations.

• BIXIBAT 5MG TABLET 10'S can be taken with or without food. There are no specific food restrictions while taking this medication. However, it is always advisable to maintain a consistent dietary pattern and avoid excessive consumption of high-fat foods, as this might affect the absorption and efficacy of the medicine. Consult your doctor or pharmacist for specific dietary advice based on your overall health condition.