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BOSUTRIS 500 TABLET 30'S
BOSUTRIS 500 TABLET 30'S
By MYLAN PHARMACEUTICALS PRIVATE LIMITED
MRP
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₹8524
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Composition
Product Details
About BOSUTRIS 500 TABLET 30'S
- **Introduction**
- BOSUTRIS 500 TABLET 30'S contains the active ingredient bosutinib. It belongs to the group of medications called Tyrosine kinase inhibitors. It is indicated to treat adult patients with a type of leukemia known as Philadelphia chromosome-positive (Ph-positive) Chronic Myeloid Leukaemia (CML) who have been newly diagnosed or for whom earlier CML treatments have either failed or have not worked or are not suitable. Philadelphia chromosome-positive chronic myelogenous leukemia is a blood cancer in which the body produces too many of a specific kind of white blood cell called granulocytes.
- BOSUTRIS 500 TABLET 30'S works by blocking the activity of the tyrosine kinase protein, which is involved in cell growth. By inhibiting this protein, the medication helps to slow down or stop the growth of leukemia cells. It is crucial to take this medication exactly as prescribed by your doctor and to continue taking it for the full course of treatment, even if you start to feel better. This helps to ensure that the leukemia cells are effectively controlled and reduces the risk of the cancer returning.
- Low white blood cell count (leukopenia), headache, shortness of breath, joint pain, dizziness, cough, back pain, decreased appetite, respiratory tract infection, raised blood pressure, ringing in the ears (tinnitus), itching, acne, dehydration, taste change, sensitivity to light and fluid on lungs are the common side effects of BOSUTRIS 500 TABLET 30'S. Inform your doctor if any of these symptoms disturb you or persist. Regular monitoring of blood counts and liver function is important while taking this medication to manage potential side effects.
- Inform your physician if you are allergic to BOSUTRIS 500 TABLET 30'S or its ingredients. Before taking this medication, report to your doctor if you have heart problems, bleeding problems, kidney and liver disorders, infection, or diarrhea. It is not recommended for children under the age of 18. Limit your time outside and use sunscreen if you must go outside, as this medicine can make you more sensitive to the sun or UV rays. It is important to discuss all your current medications and medical conditions with your doctor before starting BOSUTRIS 500 TABLET 30'S to avoid potential drug interactions or complications. Women of childbearing potential should use effective contraception during treatment and for some time after the last dose.
Uses of BOSUTRIS 500 TABLET 30'S
- Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML). This medication is used to manage and treat Ph+ CML, a specific type of leukemia characterized by the presence of the Philadelphia chromosome.
Side Effects of BOSUTRIS 500 TABLET 30'S
Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. The following are the serious and common side effects:
- Blood disorders (bleeding, fever, bruising)
- Stomach problems (stomach pain, vomiting, diarrhea, constipation, nausea)
- Hepatitis B reactivation
- Severe skin reactions
- Liver problems (yellowing of white part of eyes and skin, tea-colored urine)
- Heart problems (loss of consciousness, irregular heartbeat)
- Low white blood cell count (leukopenia)
- Headache, dizziness
- Cough, shortness of breath
- Joint pain, back pain
- Decreased appetite
- Respiratory tract infection
- Increase in blood pressure
- Ringing in the ears (tinnitus)
- Itching, acne
- Dehydration
- Taste change
- Sensitivity to light
- Fluid on lungs
Safety Advice for BOSUTRIS 500 TABLET 30'S
Pregnancy
UNSAFEBOSUTRIS 500 TABLET 30'S is unsafe to use during pregnancy as it could cause potential harm to a developing baby. Consult the doctor before taking this medicine, and it will be given to you if clearly needed. Use effective birth control during and for 30 days (one month) after the last dose.
Dosage of BOSUTRIS 500 TABLET 30'S
- Always adhere to your doctor's instructions regarding the dosage and duration of BOSUTRIS 500 TABLET 30'S. It's crucial to follow their guidance for optimal results and to minimize potential side effects.
- This medication is designed for once-daily oral administration and should be taken alongside a meal to enhance absorption and reduce stomach upset. Ensure you consume it at the same time each day to maintain a consistent level in your bloodstream.
- Swallow the tablet whole with a glass of water. Avoid crushing, breaking, or chewing the tablet, as this can alter the way the medication is released and potentially affect its efficacy. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist.
- It's important to exercise caution when handling broken or damaged tablets. Avoid direct contact with the powder, as it may cause skin irritation or other adverse reactions. If a tablet is broken, dispose of it properly according to your local guidelines.
- Continue taking BOSUTRIS 500 TABLET 30'S for the entire duration prescribed by your doctor, even if you start to feel better. Prematurely discontinuing the medication may lead to a recurrence of your condition.
How to store BOSUTRIS 500 TABLET 30'S?
- Keep BOSUTRIS 500MG TAB 1X30 away from the reach of children and pets.
- Store BOSUTRIS 500MG TAB 1X30 at room temperature.
Benefits of BOSUTRIS 500 TABLET 30'S
- BOSUTRIS 500 TABLET 30'S is a targeted therapy specifically designed to combat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). Its mechanism of action revolves around inhibiting the Bcr-Abl kinase enzyme, which is a key driver in the uncontrolled proliferation of leukemic cells. By selectively blocking this enzyme's activity, BOSUTRIS 500 TABLET 30'S effectively slows down or halts the growth and spread of cancerous cells within the bloodstream and bone marrow.
- This targeted approach minimizes damage to healthy cells, reducing the severity of side effects compared to traditional chemotherapy. By disrupting the Bcr-Abl kinase, BOSUTRIS 500 TABLET 30'S helps to restore a more normal balance in blood cell production and reduces the overall burden of leukemia in the body. This can lead to improved blood counts, reduced symptoms, and an improved quality of life for individuals living with Ph+ CML.
- Moreover, BOSUTRIS 500 TABLET 30'S offers a crucial treatment option for patients who may have developed resistance to other tyrosine kinase inhibitors (TKIs). Its effectiveness in overcoming resistance mechanisms makes it a valuable tool in the management of Ph+ CML, providing renewed hope for long-term disease control and remission.
How to use BOSUTRIS 500 TABLET 30'S
- Always take BOSUTRIS 500 TABLET 30'S exactly as your doctor has prescribed. It is crucial to adhere to the dosage and duration specified by your healthcare provider for optimal results and to minimize potential side effects. This medication is designed for once-daily administration and should be taken with food to enhance absorption and reduce the likelihood of stomach upset.
- Swallow the tablet whole with a glass of water. Avoid crushing, breaking, or chewing the tablet, as this can affect how the medication is released and absorbed into your system. If you have difficulty swallowing pills, discuss alternative options with your doctor or pharmacist.
- If the tablet is broken or damaged, avoid direct contact with the contents. Use gloves or a clean utensil to handle it carefully. It's essential to maintain the integrity of the medication to ensure its effectiveness and safety. If you accidentally touch the broken tablet, wash your hands thoroughly with soap and water immediately. Proper handling also prevents any unintended exposure or absorption of the drug through the skin.
- Consistency is key to achieving the best outcomes with BOSUTRIS 500 TABLET 30'S. Try to take it at the same time each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
FAQs
Is BOSUTRIS 500 TABLET 30'S a chemotherapy medication?
Yes, BOSUTRIS 500 TABLET 30'S is a chemotherapy medication that is indicated to treat Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) in adults.
What class of medication is BOSUTRIS 500 TABLET 30'S?
BOSUTRIS 500 TABLET 30'S belongs to the class of medications called tyrosine kinase inhibitors.
Can you crush BOSUTRIS 500 TABLET 30'S?
No, BOSUTRIS 500 TABLET 30'S should not be crushed or broken. It must be swallowed whole with a glass of water. Do not handle or touch the broken tablets.
What is the best time to take BOSUTRIS 500 TABLET 30'S?
It is best to take BOSUTRIS 500 TABLET 30'S once a day without food. Take the tablet at the same time every day for the better results.
What happens if I miss my dose of BOSUTRIS 500 TABLET 30'S?
Take the recommended dose if you miss a dose of BOSUTRIS 500 TABLET 30'S by less than 12 hours. If you miss the dose by more than 12 hours, skip the missing dose and start your next dose at the regular time.
What should be avoided in BOSUTRIS 500 TABLET 30'S?
Grapefruit, its juices, and supplement that contain grapefruit extract should be avoided during treatment with BOSUTRIS 500 TABLET 30'S as it raises the blood level in your body.
Can children use BOSUTRIS 500 TABLET 30'S?
No, BOSUTRIS 500 TABLET 30'S is not recommended for usage in children under 18.
Who is contraindicated to take BOSUTRIS 500 TABLET 30'S?
Patients who have experienced allergic reactions (hypersensitivity) to BOSUTRIS 500 TABLET 30'S or have heart or bleeding problems, kidney or liver disorders, and pregnant and breastfeeding women should not use BOSUTRIS 500 TABLET 30'S.
Does BOSUTRIS 500 TABLET 30'S interact with other drugs?
There are no known interactions of BOSUTRIS 500 TABLET 30'S with other drugs.
What advice should I follow while taking BOSUTRIS 500 TABLET 30'S?
Women taking BOSUTRIS 500 TABLET 30'S are advised to use effective contraceptives like birth control during treatment and for one month (30 days) after the last dose. Check with your healthcare provider and inform them if you take any other medications, including over-the-counter and prescription medicines, vitamins, and herbal supplements. It is suggested to use sunscreen with a good sun protection factor (SPF) because you are sensitive to sun or UV rays while taking this medication. Do not eat or drink grapefruit-containing food products as this may increase the blood level in your body.
What molecule/combination is used for making BOSUTRIS 500 TABLET 30'S?
BOSUTINIB is molecule/combination used for making BOSUTRIS 500 TABLET 30'S.
For what ailments/diseases/conditions is BOSUTRIS 500 TABLET 30'S prescribed?
BOSUTRIS 500 TABLET 30'S is prescribed for ailments/diseases/conditions related to Oncology.
References
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Reviewed on 27-07-2023
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Marketer / Manufacturer Details
MYLAN PHARMACEUTICALS PRIVATE LIMITED
Country of Origin -
India
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