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BOSUVI 400 TABLET 30'S

Name: BOSUVI 400 TABLET 30'S
Brand: GLENMARK PHARMACEUTICALS LIMITED
Price: 7912 INR
Availability: InStock

BOSUVI 400 TABLET 30'S

By GLENMARK PHARMACEUTICALS LIMITED

MRP

₹

9562.5

₹7912

17.26 % OFF

₹263.73 Only /

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Composition

BOSUTINIB 400 MG

Product Details

About BOSUVI 400 TABLET 30'S

**Introduction**
BOSUVI 400 TABLET 30'S contains the active ingredient bosutinib, a tyrosine kinase inhibitor used to treat Philadelphia chromosome-positive (Ph-positive) Chronic Myeloid Leukemia (CML) in adults. This medication is prescribed for newly diagnosed patients and those for whom previous CML treatments have been unsuccessful, ineffective, or unsuitable. Ph-positive CML is a blood cancer characterized by the overproduction of granulocytes, a type of white blood cell.
BOSUVI 400 TABLET 30'S works by targeting and inhibiting the tyrosine kinase enzymes that promote the uncontrolled growth of leukemia cells. By blocking these enzymes, the medication helps to slow down the progression of the disease and reduce the number of cancerous cells in the body. This targeted approach aims to provide a more effective treatment with potentially fewer side effects compared to traditional chemotherapy.
Common side effects associated with BOSUVI 400 TABLET 30'S include low white blood cell count (leukopenia), headache, shortness of breath, joint pain, dizziness, cough, back pain, decreased appetite, respiratory tract infection, elevated blood pressure, ringing in the ears (tinnitus), itching, acne, dehydration, altered taste, sensitivity to light, and fluid accumulation in the lungs. Patients should promptly inform their healthcare provider if any of these side effects become severe or persistent.
Before starting BOSUVI 400 TABLET 30'S, it's crucial to inform your doctor about any existing medical conditions, including heart problems, bleeding disorders, kidney or liver issues, infections, or diarrhea. This medication is generally not recommended for individuals under 18 years of age. Because BOSUVI 400 TABLET 30'S can increase sensitivity to sunlight or UV rays, it's advisable to limit sun exposure and use sunscreen when outdoors. Regular monitoring by your healthcare provider is essential during treatment to manage potential side effects and assess the medication's effectiveness.

Uses of BOSUVI 400 TABLET 30'S

Management and treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML), focusing on mitigating the proliferation of malignant cells.

Side Effects of BOSUVI 400 TABLET 30'S

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. Here's a breakdown of potential side effects associated with BOSUVI 400 TABLET 30'S.

Blood disorders (bleeding, fever, bruising)
Stomach problems (stomach pain, vomiting, diarrhea, constipation, nausea)
Hepatitis B reactivation
Severe skin reactions
Liver problems (yellowing of white part of eyes and skin, tea-colored urine)
Heart problems (loss of consciousness, irregular heartbeat)
Low white blood cell count (leukopenia)
Headache, dizziness
Cough, shortness of breath
Joint pain, back pain
Decreased appetite
Respiratory tract infection
Increase in blood pressure
Ringing in the ears (tinnitus)
Itching, acne
Dehydration
Taste change
Sensitivity to light
Fluid on lungs

Safety Advice for BOSUVI 400 TABLET 30'S

Pregnancy

UNSAFE

BOSUVI 400 TABLET 30'S is unsafe to use during pregnancy as it could cause potential harm to a developing baby. Consult the doctor before taking this medicine, and it will be given to you if clearly needed. Use effective birth control during and for 30 days (one month) after the last dose.

Dosage of BOSUVI 400 TABLET 30'S

Take BOSUVI 400 TABLET 30'S exactly as your doctor prescribes. It's crucial to follow their instructions regarding dosage and duration of treatment for optimal results. Typically, this medication is taken once daily, and it's best to take it with food to enhance absorption and minimize potential stomach upset. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
If the tablet is accidentally broken, avoid direct contact with the broken pieces. If contact occurs, wash your hands thoroughly with soap and water. This medication is potent, and handling broken tablets is not recommended. Consistent adherence to your doctor's prescribed regimen is essential for the effectiveness of BOSUVI 400 TABLET 30'S in managing your condition. Do not alter the dosage or discontinue the medication without consulting your healthcare provider, as this could affect your treatment outcome.
If you have any questions or concerns about taking BOSUVI 400 TABLET 30'S, such as potential side effects or interactions with other medications, be sure to discuss them with your doctor or pharmacist. They can provide personalized guidance and address any issues you may have.

How to store BOSUVI 400 TABLET 30'S?

Keep BOSUVI 400MG TAB 1X30 away from the reach of children and pets.
Store BOSUVI 400MG TAB 1X30 at room temperature.

Benefits of BOSUVI 400 TABLET 30'S

BOSUVI 400 TABLET 30'S is a targeted therapy medication specifically designed to combat Chronic Myelogenous Leukemia (CML), a type of blood cancer characterized by the Philadelphia chromosome (Ph+). The tablet's mechanism of action revolves around inhibiting the Bcr-Abl kinase enzyme. This enzyme is abnormally active in Ph+ CML cells, driving their uncontrolled proliferation and spread. By selectively blocking Bcr-Abl kinase, BOSUVI 400 TABLET 30'S effectively disrupts the signaling pathways that fuel cancer cell growth.
The inhibition of the Bcr-Abl kinase by BOSUVI 400 TABLET 30'S has several important consequences for the treatment of Ph+ CML. First, it helps to slow down or halt the rapid division and multiplication of cancerous cells. This reduces the overall tumor burden and prevents the disease from progressing. Second, it can induce apoptosis, or programmed cell death, in CML cells. This eliminates existing cancerous cells from the body. Finally, by targeting the underlying cause of Ph+ CML, BOSUVI 400 TABLET 30'S offers the potential for long-term disease control and improved patient outcomes. This targeted approach minimizes damage to healthy cells compared to traditional chemotherapy.
It is crucial to remember that BOSUVI 400 TABLET 30'S is prescribed and monitored by qualified healthcare professionals. Treatment decisions are based on individual patient factors, disease stage, and response to therapy. Regular monitoring is essential to assess the effectiveness of the medication and manage any potential side effects.

How to use BOSUVI 400 TABLET 30'S

Take BOSUVI 400 TABLET 30'S exactly as prescribed by your doctor. It is crucial to adhere to the dosage and duration specified by your healthcare provider for optimal results and to minimize potential side effects.
This medication is typically taken once a day, and it's recommended to take it with food. Taking it with food can help improve absorption and reduce the likelihood of stomach upset.
Swallow the tablet whole with a glass of water. Avoid breaking, crushing, or chewing the tablet, as this can affect how the medication is released and absorbed in your body. The tablet is designed for controlled release, and altering its form can disrupt this process.
If the tablet is accidentally broken, avoid direct contact with the broken pieces. Use gloves or a similar protective barrier if you need to handle them. Dispose of any broken pieces according to your local regulations for medication disposal.

FAQs

Is BOSUVI 400 TABLET 30'S a chemotherapy medication?

Yes, BOSUVI 400 TABLET 30'S is a chemotherapy medication that is indicated to treat Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) in adults.

What class of medication is BOSUVI 400 TABLET 30'S?

BOSUVI 400 TABLET 30'S belongs to the class of medications called tyrosine kinase inhibitors.

Can you crush BOSUVI 400 TABLET 30'S?

No, BOSUVI 400 TABLET 30'S should not be crushed or broken. It must be swallowed whole with a glass of water. Do not handle or touch the broken tablets.

What is the best time to take BOSUVI 400 TABLET 30'S?

It is best to take BOSUVI 400 TABLET 30'S once a day without food. Take the tablet at the same time every day for the better results.

What happens if I miss my dose of BOSUVI 400 TABLET 30'S?

Take the recommended dose if you miss a dose of BOSUVI 400 TABLET 30'S by less than 12 hours. If you miss the dose by more than 12 hours, skip the missing dose and start your next dose at the regular time.

What should be avoided in BOSUVI 400 TABLET 30'S?

Grapefruit, its juices, and supplement that contain grapefruit extract should be avoided during treatment with BOSUVI 400 TABLET 30'S as it raises the blood level in your body.

Can children use BOSUVI 400 TABLET 30'S?

No, BOSUVI 400 TABLET 30'S is not recommended for usage in children under 18.

Who is contraindicated to take BOSUVI 400 TABLET 30'S?

Patients who have experienced allergic reactions (hypersensitivity) to BOSUVI 400 TABLET 30'S or have heart or bleeding problems, kidney or liver disorders, and pregnant and breastfeeding women should not use BOSUVI 400 TABLET 30'S.

Does BOSUVI 400 TABLET 30'S interact with other drugs?

No known interactions of BOSUVI 400 TABLET 30'S with other drugs.

What is the advice for women taking BOSUVI 400 TABLET 30'S?

Women taking BOSUVI 400 TABLET 30'S are advised to use effective contraceptives like birth control during treatment and for one month (30 days) after the last dose. Check with your healthcare provider and inform them if you take any other medications, including over-the-counter and prescription medicines, vitamins, and herbal supplements. It is suggested to use sunscreen with a good sun protection factor (SPF) because you are sensitive to sun or UV rays while taking this medication. Do not eat or drink grapefruit-containing food products as this may increase the blood level in your body.

What is Bosutinib?

Bosutinib is the molecule/combination used for making BOSUVI 400 TABLET 30'S.

For which oncology-related ailments is BOSUVI 400 TABLET 30'S prescribed?

BOSUVI 400 TABLET 30'S is used for treating ailments related to Oncology.

References

Pfizer Europe MA EEIG, Electronic medicines compendium (EMC)

Pfizer, US Food and Drug Administration

Gunhild keller et al; Bosutinib; Recent Results in Cancer Research; Published on 2010

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Reviewed on 20-05-2023

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(5/5)

Nice experience, always!

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Reviewed on 24-02-2023

(5/5)

Generic medicines available at low cost

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Reviewed on 09-07-2023

(5/5)

Marketer / Manufacturer Details

GLENMARK PHARMACEUTICALS LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

BOSUVI 400 TABLET 30'S

BOSUVI 400 TABLET 30'S

Product Details

About BOSUVI 400 TABLET 30'S

Uses of BOSUVI 400 TABLET 30'S

Side Effects of BOSUVI 400 TABLET 30'S

Safety Advice for BOSUVI 400 TABLET 30'S

Dosage of BOSUVI 400 TABLET 30'S

How to store BOSUVI 400 TABLET 30'S?

Benefits of BOSUVI 400 TABLET 30'S

How to use BOSUVI 400 TABLET 30'S

FAQs

Is BOSUVI 400 TABLET 30'S a chemotherapy medication?