BRIMO 1.5% EYE DROPS 5 ML

How BRIMO 1.5% EYE DROPS 5 ML Works

• BRIMO 1.5% Eye Drops 5ml contain brimonidine, an alpha-adrenergic receptor agonist, as its active ingredient. This medication effectively lowers intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Understanding how brimonidine works is crucial to appreciating its therapeutic benefits.
• Brimonidine operates through a dual mechanism of action. Firstly, it reduces the production of aqueous humor, the fluid naturally produced within the eye. This reduction is achieved by activating alpha2-adrenergic receptors located in the ciliary body, the structure responsible for aqueous humor secretion. By stimulating these receptors, brimonidine curtails the rate at which aqueous humor is generated, thereby decreasing the overall fluid volume within the eye.
• Secondly, brimonidine enhances the outflow of aqueous humor from the eye. It does this by increasing the uveoscleral outflow, a secondary drainage pathway. Activation of alpha2-adrenergic receptors appears to facilitate fluid movement through this alternative route, further contributing to the lowering of IOP. This dual action – reduced production and increased outflow – makes brimonidine particularly effective in managing elevated eye pressure.
• In simpler terms, imagine the eye as a sink. Aqueous humor is the water flowing into the sink, and the eye's natural drainage system is the drain. In glaucoma or ocular hypertension, either too much 'water' (aqueous humor) is being produced, or the 'drain' isn't working efficiently, causing the 'water level' (IOP) to rise. BRIMO 1.5% Eye Drops work by both turning down the 'faucet' (reducing aqueous humor production) and helping to clear the 'drain' (increasing uveoscleral outflow), thus lowering the 'water level' (IOP) and protecting the optic nerve from damage.
• The selective alpha2-adrenergic agonist activity of brimonidine also contributes to its relatively favorable side effect profile compared to non-selective adrenergic agonists. This selectivity means it primarily targets the intended receptors in the eye, minimizing effects on other parts of the body.
• The combined effect of reduced aqueous humor production and enhanced uveoscleral outflow leads to a significant decrease in intraocular pressure, protecting the optic nerve from further damage and preserving vision. Regular and consistent use of BRIMO 1.5% Eye Drops, as prescribed by an ophthalmologist, is essential for maintaining optimal IOP control and preventing the progression of glaucoma or ocular hypertension.

Common side effects of BRIMO 1.5% Eye Drops may include: * Burning or stinging sensation in the eye * Blurred vision * Dry eyes * Itching of the eye * Foreign body sensation in the eye * Redness of the eye * Tearing * Headache * Drowsiness * Dry mouth Less common side effects may include: * Eye pain * Eyelid swelling * Conjunctivitis (pink eye) * High blood pressure * Low blood pressure * Dizziness * Nausea * Fatigue * Depression * Skin rash Rare side effects may include: * Fainting * Slow heart rate * Difficulty breathing * Insomnia

• If you miss a dose of BRIMO 1.5% Eye Drops, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

• Keep BRIMO 1.5% EYE DROPS 5ML away from the reach of children and pets.
• Store BRIMO 1.5% EYE DROPS 5ML at room temperature.

• **Use as Prescribed:** Always use BRIMO 1.5% Eye Drops exactly as your doctor has instructed. The dosage and frequency are tailored to your specific condition, and deviating from the prescribed regimen can impact the effectiveness of the treatment and potentially increase the risk of side effects. Consistency is key for optimal results in managing elevated eye pressure.Do not increase or decrease the dosage without consulting your doctor.
• **Proper Instillation Technique:** Ensure proper administration to maximize the benefits of BRIMO 1.5% Eye Drops and minimize potential side effects. Wash your hands thoroughly before each use. Tilt your head back slightly, and gently pull down your lower eyelid to create a small pocket. Hold the dropper above your eye and squeeze out one drop into the pocket, avoiding contact between the dropper tip and your eye or surrounding surfaces to prevent contamination. Close your eye gently for 1-2 minutes and avoid blinking or squeezing your eyelids tightly, as this can push the medication out of your eye. Use a clean tissue to wipe away any excess solution from around your eye.
• **Monitor for Side Effects:** Be vigilant for any potential side effects while using BRIMO 1.5% Eye Drops and promptly report them to your doctor. Common side effects may include eye redness, itching, stinging, blurred vision, dry mouth, and drowsiness. While most side effects are mild and temporary, some individuals may experience more severe reactions such as allergic reactions or significant changes in blood pressure. If you notice any unusual or concerning symptoms, discontinue use and seek medical attention immediately.
• **Contact Lens Considerations:** If you wear contact lenses, remove them before instilling BRIMO 1.5% Eye Drops and wait at least 15 minutes before reinserting them. This is because some eye drops contain preservatives that can be absorbed by contact lenses and cause irritation or damage to the cornea. Allowing sufficient time between instillation and lens insertion ensures that the medication is properly absorbed and minimizes the risk of adverse effects.
• **Storage and Handling:** Store BRIMO 1.5% Eye Drops properly to maintain its stability and effectiveness. Keep the bottle tightly closed when not in use and store it at room temperature, away from direct sunlight and heat. Do not store the eye drops in the bathroom, as the humidity can degrade the medication. Keep the bottle out of reach of children and pets. Do not use the eye drops if the solution changes color or contains particles. Properly discard the bottle after the expiration date or if the solution appears contaminated.

• There are no known interactions between BRIMO 1.5% Eye Drops and food. You can use this medication without regard to meals.