BUCELON 2 TABLET 25'S
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BUCELON 2 TABLET 25'S
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BUCELON 2 TABLET 25'S

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BUCELON 2 TABLET 25'S

By CELON LABORATORIES LTD

MRP

114

₹108.3

5 % OFF

₹4.33 Only /

Tablet

10

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Product DetailsArrow

About BUCELON 2 TABLET 25'S

  • BUCELON 2 TABLET 25'S is a chemotherapy drug used to treat certain types of blood cancers. It belongs to a class of medications called alkylating agents. Specifically, it is an alkyl sulfonate. This medication is primarily used in the treatment of chronic myelogenous leukemia (CML), a cancer that causes an overproduction of white blood cells in the bone marrow. It works by damaging the DNA of cancer cells, which helps to stop their growth and spread.
  • BUCELON 2 TABLET 25'S is also utilized as a conditioning treatment before a bone marrow transplant. In this setting, it helps to prepare the bone marrow to receive healthy blood-forming stem cells from a donor. This is crucial when the patient's own stem cells have been damaged or destroyed by radiation or high doses of chemotherapy. By suppressing the existing bone marrow, it creates space for the new, healthy cells to engraft and begin producing normal blood cells.
  • Chronic myelogenous leukemia is a type of cancer that originates in the bone marrow, the soft tissue responsible for producing blood cells. This condition leads to a significant increase in the number of white blood cells, which can interfere with the production of other blood cells. Common side effects associated with BUCELON 2 TABLET 25'S include a decrease in white blood cell count, dizziness, shortness of breath, mouth inflammation (mucositis), nausea, diarrhea, difficulty sleeping (insomnia), and fever. It is essential to maintain adequate hydration by drinking plenty of fluids while taking this medication to help manage some of these side effects.
  • It's important to note that BUCELON 2 TABLET 25'S can significantly suppress bone marrow activity, increasing the risk of infections and bleeding. Patients should inform their healthcare provider about any other medications they are taking, including prescription and over-the-counter drugs, as some medications can further decrease blood cell counts. Due to its impact on the immune system, BUCELON 2 TABLET 25'S can make individuals more susceptible to infections, some of which may be serious or even life-threatening. Patients should promptly contact their doctor if they experience any signs of infection, such as fever, chills, cough, mouth sores, or unusual bleeding or bruising.

Uses of BUCELON 2 TABLET 25'S

  • Hematopoietic progenitor cell transplantation (a procedure to replace damaged or diseased blood-forming cells with healthy ones)
  • Chronic myelogenous leukemia (a slowly progressing type of blood cancer that begins in the bone marrow)
  • Polycythemia vera (a type of blood cancer that causes an overproduction of red blood cells, leading to thickening of the blood)
  • Thrombocythemia (a condition characterized by an increased number of platelets in the blood, potentially leading to blood clots)
  • Myelofibrosis (a type of bone marrow cancer where scar tissue forms in the bone marrow, disrupting the production of normal blood cells)
  • Hemoglobinopathies (a group of genetic disorders that result in abnormal hemoglobin structure or production)

Side Effects of BUCELON 2 TABLET 25'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. Severe side effects include myelosuppression (decreased bone marrow activity).

  • Thalassaemia
  • Hair loss
  • Patches of dark skin
  • Blood in urine
  • Decrease in the number of blood cells and platelets
  • Nausea and vomiting
  • Jaundice
  • Infertility and sterility
  • Pneumonia syndrome

Safety Advice for BUCELON 2 TABLET 25'SArrow

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Pregnancy

UNSAFE

BUCELON 2 TABLET 25'S is unsafe during pregnancy. It may cause fetal harm when administered. If you are pregnant or planning to get pregnant, ask your doctor or pharmacist for advice before taking this medicine. This applies to men and women because the drug may harm your sperm or eggs.

Dosage of BUCELON 2 TABLET 25'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with BUCELON 2 TABLET 25'S. The specific dosage will depend on the type and severity of your blood cancer, as well as your individual response to the medication. It is crucial to follow your doctor's instructions precisely.
  • Swallow BUCELON 2 TABLET 25'S whole with a large glass of water. Avoid breaking, crushing, or chewing the tablets, as this can affect how the medication is absorbed into your system. You can take BUCELON 2 TABLET 25'S either before or after meals; consistency in timing is generally recommended.
  • Do not discontinue taking BUCELON 2 TABLET 25'S unless your doctor explicitly advises you to do so. Stopping the medication prematurely can have serious consequences and may negatively impact your treatment outcome. If you experience any side effects or have concerns, discuss them with your doctor.
  • If you miss a dose of BUCELON 2 TABLET 25'S, do not take a double dose to compensate. Instead, take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Always inform your doctor about any missed doses.

How to store BUCELON 2 TABLET 25'S?Arrow

  • Keep BUCELON 2MG TAB 1X25 away from the reach of children and pets.
  • Store BUCELON 2MG TAB 1X25 at room temperature.

Benefits of BUCELON 2 TABLET 25'SArrow

  • BUCELON 2 TABLET 25'S works by disrupting the essential DNA replication process within cells, a process crucial for their division and proliferation. By interfering with this process, BUCELON 2 TABLET 25'S effectively inhibits the growth of tumors by preventing cancer cells from dividing and multiplying uncontrollably.
  • The mechanism of action involves the reversible binding of the medication to nucleophilic groups present on various cellular components, leading to cytotoxicity. While multiple interactions occur, the alkylation of DNA is considered the most critical cytotoxic reaction responsible for eliminating tumor cells. This alkylation process directly damages the DNA and RNA of cancer cells, effectively halting their growth and replication.
  • In essence, BUCELON 2 TABLET 25'S targets the very core of cancer cell division, causing irreparable damage and ultimately leading to cell death. Due to its mechanism, it is frequently used in combination with other chemotherapeutic agents to combat a wide array of lymphatic and solid cancers, maximizing the therapeutic effect and improving patient outcomes. This combined approach helps to attack the cancer cells from multiple angles, increasing the likelihood of successful treatment.

How to use BUCELON 2 TABLET 25'SArrow

  • Your physician will determine the appropriate dosage and duration of treatment with BUCELON 2 TABLET 25'S. The dosage is specifically tailored to your type of blood cancer. Administer BUCELON 2 TABLET 25'S orally with ample water. It is crucial to swallow the tablets whole, avoiding any breaking, crushing, or chewing. You can take BUCELON 2 TABLET 25'S either before or after your meals, maintaining a consistent schedule each day for optimal results.
  • Adhere strictly to your doctor's instructions regarding the use of BUCELON 2 TABLET 25'S. Do not discontinue the medication unless explicitly advised by your healthcare provider, even if you start feeling better. Prematurely stopping the medication can lead to a resurgence of your condition and impede the effectiveness of the treatment. It is very important to complete the full course of therapy as prescribed.
  • In the event that you miss a dose of BUCELON 2 TABLET 25'S, it is important not to compensate by taking double the dose at the next scheduled time. This could lead to serious side effects. Instead, inform your physician about the missed dose, and they will provide guidance on how to proceed. They might advise you to take the missed dose as soon as you remember, or they might suggest skipping it and continuing with your regular dosing schedule. Always follow their specific instructions to ensure your safety and the effectiveness of the treatment.

FAQs

Can BUCELON 2 TABLET 25'S cause infertility?Arrow

Yes, BUCELON 2 TABLET 25'S can cause infertility in both the men and women because it affects the sperm cells and egg. Consult the doctor before taking this medication.

How can a Busulfan 2 mg tablet be taken?Arrow

BUCELON 2 TABLET 25'S is taken orally. Swallow the whole tablet with water. If you have missed the dose, inform your physician. Don't take double the dose.

Can BUCELON 2 TABLET 25'S be used during pregnancy?Arrow

No, it is highly unsafe to use this medication during pregnancy as they can cause harmful effects on the developing fetus.

Are there any special precautions patients should be aware of before starting treatment?Arrow

Patients should inform the physician about the pregnancy, breastfeeding, or if planning for a family. Patients should also inform about past medical and medication history.

What is the package insert that comes with BUCELON 2 TABLET 25'S?Arrow

The package insert contains all the scientific information(indications, uses, side effects, safety, and warning, contraindications) about the drug.

Does BUCELON 2 TABLET 25'S cause permanent hair loss?Arrow

Yes, BUCELON 2 TABLET 25'S chemotherapy causes hair loss. Consult the physician about excessive hair loss.

What does a BUCELON 2 TABLET 25'S look like?Arrow

It looks like a white, scored tablet packed in a bottle containing 25 tablets per bottle.

Is there any drug interaction with BUCELON 2 TABLET 25'S?Arrow

NULL interaction of BUCELON 2 TABLET 25'S with other drugs

What special precautions should I follow while taking BUCELON 2 TABLET 25'S?Arrow

Inform the doctor if the patient has taken radiotherapy priorly to the treatment. If you have other medical conditions like heart disease, lung, kidney, or liver problems. Tell your doctor if you have gout symptoms (pain and swollen joints caused by uric acid crystals).

What molecule/combination is used for making BUCELON 2 TABLET 25'S?Arrow

BUSULFAN is molecule/combination used for making BUCELON 2 TABLET 25'S.

For which ailments/diseases/conditions is BUCELON 2 TABLET 25'S prescribed in Oncology?Arrow

BUCELON 2 TABLET 25'S is prescribed for various ailments/diseases/conditions in Oncology.

References

Book Icon

Aspen, Electronic Medicines Compendium(EMC)

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Busulfan National Cancer Institute

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Buggia I, Locatelli F, Regazzi MB, Zecca M. Busulfan. Ann Pharmacother. 1994 Sep;28(9):1055-62. doi: 10.1177/106002809402800911. PMID: 7803883.

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Marketer / Manufacturer Details

CELON LABORATORIES LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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