BUSEFAN 60 INJECTION
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BUSEFAN 60 INJECTION
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BUSEFAN 60 INJECTION

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BUSEFAN 60 INJECTION

By HALSTED PHARMA PVT LTD

MRP

₹

8100

₹5163

36.26 % OFF

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Composition

BUSULFAN 60 MG

Product DetailsArrow

About BUSEFAN 60 INJECTION

  • BUSEFAN 60 INJECTION is a chemotherapy drug used to treat cancer. It contains Busulfan, an alkyl sulfonate that acts as an alkylating agent to fight cancer cells. It is primarily used in the treatment of chronic myelogenous leukemia (CML), a type of cancer affecting white blood cells. It's also used as part of a conditioning regimen before hematopoietic progenitor cell transplantation, a procedure where healthy stem cells replace damaged ones.
  • Chronic myelogenous leukemia is a slowly progressing cancer that starts in the bone marrow, the tissue responsible for producing blood cells. CML leads to an elevated white blood cell count. While it mainly affects older adults, it can occur in any age group, though it's rare in children. Treatment with BUSEFAN 60 INJECTION can significantly reduce bone marrow activity. Therefore, it's crucial to inform your doctor about any other medications you are taking, especially if they also lower blood cell counts, to avoid potential complications.
  • BUSEFAN 60 INJECTION works by damaging the DNA of cancer cells, preventing them from multiplying and spreading. This helps to control the growth of the leukemia and prepare the body for a stem cell transplant, if necessary. Regular blood tests are essential during treatment to monitor blood cell counts and ensure the medication is working effectively. The dosage and duration of treatment will be determined by your doctor based on your individual condition and response to the drug. Be sure to discuss any concerns or side effects with your healthcare provider.

Uses of BUSEFAN 60 INJECTION

  • Hematopoietic progenitor cell transplantation, a procedure to replace damaged or diseased bone marrow with healthy cells to restore normal blood cell production.
  • Chronic myelogenous leukemia, a type of cancer that affects the blood and bone marrow, characterized by the overproduction of white blood cells.
  • Polycythemia vera, a type of cancer that causes an overproduction of red blood cells, leading to thickening of the blood and potential complications.
  • Thrombocythemia, a condition characterized by an increased number of platelets in the blood, which can lead to blood clots or bleeding problems.
  • Myelofibrosis, a type of blood cancer in which scar tissue forms in the bone marrow, disrupting the production of normal blood cells.
  • Hemoglobinopathies, genetic disorders that result in the production of abnormal hemoglobin, affecting the oxygen-carrying capacity of red blood cells.
  • Congenital metabolic diseases, inherited disorders present from birth that affect the body's ability to process certain substances.

Side Effects of BUSEFAN 60 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. BUSEFAN 60 INJECTION causes the following side effects:

  • Myelosuppression (decreased bone marrow activity)
  • Thalassemia
  • Skin rashes
  • Hair loss
  • Patches of dark skin
  • Blood in urine
  • Decrease in the number of blood cells and platelets
  • Nausea and vomiting
  • Jaundice
  • Infertility and sterility
  • Pneumonia Syndrome
  • Itching

Safety Advice for BUSEFAN 60 INJECTIONArrow

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Pregnancy

UNSAFE

BUSEFAN 60 INJECTION comes under pregnancy category D. It may cause foetal harm when administered. If you are pregnant or planning for pregnancy, ask your doctor or pharmacist for advice before taking this medicine. This applies to both men and women because the drug may harm your sperm or eggs.

Dosage of BUSEFAN 60 INJECTIONArrow

  • Your physician will determine the most appropriate formulation, dose, and duration of treatment with BUSEFAN 60 INJECTION, considering your specific condition and medical history. The precise dose of BUSEFAN 60 INJECTION is carefully calculated based on factors such as your body weight and the specific type of blood cancer you have. It's crucial to understand that BUSEFAN 60 INJECTION is a medication that requires professional administration.
  • If BUSEFAN 60 INJECTION has been prescribed for you, a qualified healthcare professional will administer the injection through intravenous infusion, directly into a vein. This ensures the medication is delivered safely and effectively. It is essential not to attempt self-administration of this medication.
  • Adhere strictly to your doctor's instructions regarding the duration of treatment. Do not discontinue the medication prematurely unless explicitly advised by your physician, as this could negatively impact your treatment outcomes. If you happen to miss a scheduled dose, promptly inform your physician. Do not attempt to compensate by taking a double dose to make up for the missed one, as this could lead to adverse effects.
  • Your doctor may adjust the dosage based on your body weight and response to the treatment. It is very important to adhere to the prescribed dosage and schedule and also to report any side effects immediately.

How to store BUSEFAN 60 INJECTION?Arrow

  • Keep BUSEFAN 60MG INJ 10ML away from the reach of children and pets.
  • Store BUSEFAN 60MG INJ 10ML at room temperature.

Benefits of BUSEFAN 60 INJECTIONArrow

  • BUSEFAN 60 INJECTION is a medication designed to combat tumor growth by disrupting the fundamental process of cell division. At its core, BUSEFAN 60 INJECTION works by actively interfering with DNA replication, a crucial step that every cell must undergo before it can successfully divide into two new cells. This interference is what makes BUSEFAN 60 INJECTION effective at inhibiting the proliferation of cancer cells. The drug essentially throws a wrench into the cellular machinery responsible for duplicating DNA, preventing the cells from accurately copying their genetic material. Without this accurate duplication, cells cannot divide properly, which ultimately hinders the growth and spread of tumors. By halting the cell division process, BUSEFAN 60 INJECTION effectively puts a brake on the expansion of cancerous tissues, providing a valuable tool in the fight against cancer. This targeted action is essential for managing and controlling the progression of the disease.
  • The primary mechanism of BUSEFAN 60 INJECTION involves specifically targeting the DNA replication process within cells. This targeted approach helps to minimize the impact on healthy cells, although some side effects may still occur. When a cell attempts to divide, it must first create an exact copy of its DNA. BUSEFAN 60 INJECTION steps in during this stage, disrupting the replication process and introducing errors. These errors prevent the cell from successfully dividing, leading to cell cycle arrest or even cell death. Cancer cells, which are characterized by their rapid and uncontrolled division, are particularly vulnerable to this disruption. By specifically inhibiting the replication of DNA, BUSEFAN 60 INJECTION helps to slow down or stop the growth of tumors. This mechanism is critical for controlling the disease and improving patient outcomes.
  • Furthermore, BUSEFAN 60 INJECTION's method of action offers a strategic advantage in cancer treatment. By focusing on a fundamental process necessary for cell division, it can be effective against a wide range of cancer types. The drug's ability to interfere with DNA replication means that it can target any cell that is actively dividing, regardless of its specific origin or characteristics. This broad applicability makes BUSEFAN 60 INJECTION a valuable component of many cancer treatment regimens. In essence, BUSEFAN 60 INJECTION serves as a powerful tool that directly tackles the core issue of uncontrolled cell growth in cancer, by precisely targeting and disrupting the process of DNA replication within these cells.

How to use BUSEFAN 60 INJECTIONArrow

  • Your physician will determine the appropriate formulation, dosage, and duration of your treatment with BUSEFAN 60 INJECTION. The specific dose will depend on the type and severity of your blood cancer and your individual health condition. If BUSEFAN 60 INJECTION is prescribed, it will be administered by a trained healthcare professional. It is crucial that you do not attempt to self-administer this medication.
  • BUSEFAN 60 INJECTION is given as an intravenous infusion, meaning it's slowly injected directly into a vein. The infusion process will be carefully monitored by medical staff. It is important to adhere to the prescribed treatment schedule and to continue taking the medication for the full duration advised by your doctor. Do not discontinue the medication prematurely without consulting your physician, even if you start feeling better.
  • If you happen to miss a scheduled dose, contact your healthcare provider immediately for guidance. Do not attempt to compensate for the missed dose by doubling the next dose. Taking a double dose can be dangerous and may lead to adverse effects. Always inform your physician promptly about any missed doses so they can adjust your treatment plan accordingly.

FAQs

<p><strong>Can BUSEFAN 60 INJECTION cause infertility?</strong></p>Arrow

Yes, BUSEFAN 60 INJECTION can cause infertility in both the men and women because it affects the sperm cells and egg. Consult the doctor before taking this medication.

<p><strong>Can BUSEFAN 60 INJECTION be used during pregnancy?</strong></p>Arrow

No, it is highly unsafe to use this medication during pregnancy as they can cause harmful effects on the developing foetus.

<p><strong>Are there any special precautions patients should be aware of before starting treatment?</strong></p>Arrow

Patients should inform the physician about the pregnancy, breastfeeding or if planning for a family. Patients should also inform about the past medical and medication history.

<p><strong>What is the package insert that comes with BUSEFAN 60 INJECTION?</strong></p>Arrow

Package insert contains all the scientific information(indications, uses, side effects, safety and warning, contraindications) about the drug.

<p><strong>Does BUSEFAN 60 INJECTION cause permanent hair loss?</strong></p>Arrow

Yes, BUSEFAN 60 INJECTION chemotherapy causes hair loss. Consult the physician about excessive hair loss.

NULL interaction of BUSEFAN 60 INJECTION with other drungsArrow

NULL

<p>Inform the doctor if the patient has taken radiotherapy priorly to the treatment. If you have any other medical conditions like heart disease, lung, kidney, or liver problems. Tell your doctor if you have any symptoms of gout (pain and swollen joints caused by uric acid crystals). During or after administration of the injection, if you face itchy skin, fever, excessive sweating, rigors or chills, or difficulty in breathing, inform your doctor immediately.</p>Arrow

Inform the doctor if the patient has taken radiotherapy priorly to the treatment. If you have any other medical conditions like heart disease, lung, kidney, or liver problems. Tell your doctor if you have any symptoms of gout (pain and swollen joints caused by uric acid crystals). During or after administration of the injection, if you face itchy skin, fever, excessive sweating, rigors or chills, or difficulty in breathing, inform your doctor immediately.

What is Busulfan and what is it used for?Arrow

Busulfan is a molecule/combination used for making BUSEFAN 60 INJECTION. It is a chemotherapy drug used to treat certain types of cancer.

For what type of cancer BUSEFAN 60 INJECTION is prescribed?Arrow

BUSEFAN 60 INJECTION is mainly used in Oncology, which means it is prescribed for cancer treatment.

References

Book Icon

Aspen, Electronic Medicines Compendium(EMC)

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Busulfan National Cancer Institute

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Buggia I, Locatelli F, Regazzi MB, Zecca M. Busulfan. Ann Pharmacother. 1994 Sep;28(9):1055-62. doi: 10.1177/106002809402800911. PMID: 7803883.

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Reviewed on 10-02-2023

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Marketer / Manufacturer Details

HALSTED PHARMA PVT LTD

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BUSEFAN 60 INJECTION

BUSEFAN 60 INJECTION

MRP

₹

8100

₹5163

36.26 % OFF

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