CANAROS AS 20 TABLET 10'S

How CANAROS AS 20 TABLET 10'S Works

• CANAROS AS 20 Tablet is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Canagliflozin and Sitagliptin, each working through different mechanisms to achieve optimal glycemic control. Canagliflozin belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. The kidneys filter glucose from the blood, and SGLT2 proteins are responsible for reabsorbing most of this glucose back into the bloodstream. Canagliflozin selectively inhibits SGLT2 in the kidneys. By blocking SGLT2, Canagliflozin reduces the reabsorption of glucose, leading to increased glucose excretion in the urine. This directly lowers blood glucose levels. This mechanism is insulin-independent, meaning it works even if the body isn't producing enough insulin or is resistant to insulin's effects. In addition to lowering blood sugar, Canagliflozin can also lead to modest weight loss and blood pressure reduction in some individuals.
• Sitagliptin, the second active ingredient in CANAROS AS 20 Tablet, belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released from the gut in response to food intake. These hormones stimulate insulin release from the pancreas and reduce glucagon secretion from the liver, both of which help lower blood sugar levels. Sitagliptin inhibits the DPP-4 enzyme, preventing the breakdown of incretin hormones. This results in increased levels of active incretin hormones in the body, leading to enhanced insulin secretion and reduced glucagon secretion in a glucose-dependent manner. This means that Sitagliptin's effects on insulin and glucagon are more pronounced when blood sugar levels are high, minimizing the risk of hypoglycemia (low blood sugar).
• In summary, CANAROS AS 20 Tablet works through a dual mechanism: Canagliflozin increases glucose excretion in the urine by inhibiting SGLT2, while Sitagliptin enhances the effects of incretin hormones by inhibiting DPP-4. This combination approach can effectively lower blood sugar levels in individuals with type 2 diabetes, providing better glycemic control compared to either medication alone. It's crucial to use this medication as prescribed by your healthcare provider, alongside lifestyle modifications such as diet and exercise, for optimal diabetes management. Monitoring blood sugar levels regularly is also essential to assess the medication's effectiveness and adjust the dosage if needed. Always consult your doctor for personalized advice and management of your diabetes.

Common side effects of Canaros AS 20 Tablet may include nausea, vomiting, stomach pain, heartburn, diarrhea, constipation, headache, dizziness, and increased risk of bleeding. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling), liver problems (yellowing of skin/eyes, dark urine), kidney problems (changes in urination), and gastrointestinal ulcers or bleeding (black stools, persistent stomach pain). Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of CANAROS AS 20 TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep CANAROS AS 20MG TAB 1X10 away from the reach of children and pets.
• Store CANAROS AS 20MG TAB 1X10 at room temperature.

• Take CANAROS AS 20 TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting your healthcare provider to ensure optimal therapeutic effects and minimize potential side effects. This medication is typically taken once daily, but your doctor will determine the most appropriate regimen based on your specific health condition.
• CANAROS AS 20 TABLET 10'S is often prescribed to help manage high cholesterol and reduce the risk of cardiovascular events. Maintaining a heart-healthy lifestyle, including a balanced diet low in saturated fats and cholesterol, regular exercise, and avoiding smoking, can significantly enhance the medication's effectiveness and improve your overall cardiovascular health.
• If you experience any unusual or severe side effects while taking CANAROS AS 20 TABLET 10'S, such as muscle pain or weakness, unexplained fever, or changes in urine color, promptly inform your doctor. These symptoms could indicate a rare but serious condition called rhabdomyolysis, which requires immediate medical attention. Do not ignore these symptoms, as early detection and treatment are crucial.
• Store CANAROS AS 20 TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Ensure that the medication is kept out of reach of children and pets to prevent accidental ingestion. Proper storage helps maintain the drug's stability and effectiveness throughout its shelf life. Do not store it in the bathroom, as the humidity can affect the medication.
• Before starting CANAROS AS 20 TABLET 10'S, inform your doctor about all other medications, supplements, and herbal products you are currently taking. Certain drugs can interact with this medication, potentially affecting its efficacy or increasing the risk of side effects. Provide a complete list of your medications to your doctor to ensure they can make informed decisions about your treatment plan. Also, be sure to mention any allergies or pre-existing medical conditions.

• CANAROS AS 20 TABLET 10'S can be taken with or without food. However, it is generally recommended to take it after food to avoid stomach upset.
• Avoid consuming large amounts of grapefruit juice while taking this medicine, as it may increase the levels of the drug in your body.