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CLAVAM XR TABLET 10'S

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CLAVAM XR TABLET 10'S

By ALKEM LABORATORIES LIMITED

MRP

580

₹493

15 % OFF

₹49.3 Only /

Tablet

10

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Product DetailsArrow

About CLAVAM XR TABLET 10'S

  • CLAVAM XR TABLET 10'S is a powerful antibiotic combination designed to combat a wide range of bacterial infections. It contains two active ingredients: Amoxicillin and Clavulanate Potassium. Amoxicillin is a penicillin-like antibiotic that works by interfering with the ability of bacteria to form cell walls, thus weakening and killing the bacteria. However, some bacteria produce an enzyme called beta-lactamase, which can inactivate Amoxicillin.
  • Clavulanate Potassium steps in as a beta-lactamase inhibitor. It binds to and deactivates the beta-lactamase enzyme, preventing it from breaking down Amoxicillin. This allows Amoxicillin to remain effective against a broader spectrum of bacteria, including those that are resistant to Amoxicillin alone. Together, these two components work synergistically to provide a robust defense against bacterial infections.
  • CLAVAM XR TABLET is an extended-release formulation, meaning it releases the medication slowly over a prolonged period. This provides a more consistent level of the drug in the bloodstream, potentially reducing the frequency of dosing and improving patient compliance. It is typically prescribed for infections such as respiratory tract infections (e.g., pneumonia, bronchitis, sinusitis), urinary tract infections, skin and soft tissue infections, and bone and joint infections. Always follow the dosage and duration prescribed by your healthcare provider for optimal results. Ensure you complete the entire course of treatment, even if you start feeling better, to prevent the recurrence of infection and the development of antibiotic resistance.
  • Before taking CLAVAM XR TABLET, inform your doctor about any allergies, especially to penicillin or other beta-lactam antibiotics. Also, disclose any existing medical conditions, such as kidney or liver problems, and all other medications you are taking. Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. If you experience any severe or persistent side effects, seek medical attention immediately. This medication should be used with caution during pregnancy and breastfeeding, and only if clearly needed and prescribed by a healthcare professional.

Uses of CLAVAM XR TABLET 10'S

  • Treatment of Pneumonia
  • Treatment of Bronchitis
  • Treatment of Sinusitis
  • Treatment of Skin and Soft Tissue Infections
  • Treatment of Urinary Tract Infections (UTIs)
  • Treatment of Ear Infections (Otitis Media)
  • Treatment of Throat Infections (Pharyngitis/Tonsillitis)
  • Treatment of Bone and Joint Infections
  • Treatment of Septicemia (Blood Infection)
  • Prevention of Surgical Site Infections
  • Treatment of Dental Infections

How CLAVAM XR TABLET 10'S Works

  • CLAVAM XR TABLET 10'S is a powerful antibiotic combination medication containing amoxicillin and clavulanate. It works by targeting and eliminating bacteria that cause infections. Amoxicillin, a penicillin-like antibiotic, disrupts the formation of bacterial cell walls, leading to bacterial cell death. However, some bacteria produce an enzyme called beta-lactamase, which can inactivate amoxicillin, rendering it ineffective.
  • This is where clavulanate comes in. Clavulanate is a beta-lactamase inhibitor. It binds to and deactivates the beta-lactamase enzyme, preventing it from breaking down amoxicillin. By inhibiting beta-lactamase, clavulanate allows amoxicillin to reach its target and effectively kill the bacteria. This synergistic action of amoxicillin and clavulanate makes CLAVAM XR TABLET 10'S effective against a wide range of bacterial infections.
  • The 'XR' in CLAVAM XR TABLET 10'S stands for extended-release. This means that the medication is released slowly into your system over a longer period. This extended-release formulation helps to maintain a consistent level of the antibiotics in your body, which helps to kill the bacteria more effectively and reduces the frequency of dosing. The extended-release mechanism ensures prolonged antibacterial action, maximizing the therapeutic effect and minimizing the potential for bacterial resistance. Therefore, it is important to take the medication exactly as prescribed by your doctor, to ensure you get the maximum benefit from it.
  • Specifically, amoxicillin inhibits the synthesis of bacterial peptidoglycans, which are essential components of bacterial cell walls. By disrupting the cell wall synthesis, amoxicillin weakens the bacterial cell wall, eventually leading to cell lysis and death. Clavulanic acid, on the other hand, acts as a 'suicide inhibitor' for beta-lactamase enzymes. It binds irreversibly to the active site of these enzymes, preventing them from degrading amoxicillin. This combination ensures that a higher concentration of amoxicillin remains active, effectively combating the infection.
  • In summary, CLAVAM XR TABLET 10'S works by a dual mechanism: amoxicillin directly targets and destroys bacteria by inhibiting cell wall synthesis, while clavulanate protects amoxicillin from being inactivated by bacterial enzymes. The extended-release formulation provides sustained drug levels for optimal therapeutic effect. This makes CLAVAM XR TABLET 10'S a potent treatment option for various bacterial infections.

Side Effects of CLAVAM XR TABLET 10'SArrow

Like all medicines, CLAVAM XR TABLET 10'S can cause side effects, although not everybody gets them. The following are some potential side effects: **Common Side Effects (may affect up to 1 in 10 people):** * Diarrhea * Nausea * Vomiting * Fungal infection of the skin and mucous membranes **Uncommon Side Effects (may affect up to 1 in 100 people):** * Indigestion * Dizziness * Headache * Skin rash, itching * Urticaria (hives) * Increase in some substances (enzymes) in the blood produced by the liver **Rare Side Effects (may affect up to 1 in 1,000 people):** * Thrombocytopenia (low blood platelet count) * Leukopenia (low white blood cell count) * Erythema multiforme **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Allergic reactions (including anaphylaxis which can be life-threatening) * Drug-induced aseptic meningitis * Hemolytic anemia * Prolongation of bleeding time and prothrombin time * Black hairy tongue * Hepatitis * Cholestatic jaundice * Stevens-Johnson syndrome * Toxic epidermal necrolysis * Exfoliative dermatitis * Convulsions (seizures) * Crystalluria **Side effects with unknown frequency:** * Clostridium difficile-associated diarrhea * Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)

Safety Advice for CLAVAM XR TABLET 10'SArrow

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Allergies

Allergies

Do not use CLAVAM XR TABLET 10'S if you are allergic to it.

Dosage of CLAVAM XR TABLET 10'SArrow

  • The recommended dosage of CLAVAM XR TABLET 10'S varies depending on the severity of the infection, the patient's age, weight, kidney function, and overall health condition. It's crucial to adhere to your doctor's specific instructions regarding dosage and duration of treatment. Do not self-medicate or alter the dosage without consulting your healthcare provider.
  • For adults and children weighing 40 kg or more, the usual dose is one CLAVAM XR tablet every 12 hours. The tablet should be swallowed whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect the extended-release mechanism and alter the absorption of the medication.
  • The duration of treatment typically ranges from 5 to 14 days, depending on the type and severity of the infection. It is important to complete the full course of antibiotics, even if you start feeling better after a few days. Stopping the medication prematurely can lead to incomplete eradication of the infection and increase the risk of antibiotic resistance.
  • If you have kidney problems, your doctor may need to adjust the dosage of CLAVAM XR to prevent the drug from accumulating in your body. Similarly, if you are elderly, your doctor may prescribe a lower dose due to age-related changes in kidney and liver function.
  • CLAVAM XR is best taken with food to minimize the risk of gastrointestinal side effects such as nausea, vomiting, and diarrhea. If you experience persistent or severe side effects, contact your doctor.
  • In case you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure, consult with your doctor or pharmacist.
  • Take 'CLAVAM XR TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of CLAVAM XR TABLET 10'S?Arrow

  • If you miss a dose of CLAVAM XR TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store CLAVAM XR TABLET 10'S?Arrow

  • Keep CLAVAM XR TAB 1X10 away from the reach of children and pets.
  • Store CLAVAM XR TAB 1X10 at room temperature.

Benefits of CLAVAM XR TABLET 10'SArrow

  • CLAVAM XR Tablet 10'S is a powerful combination antibiotic medication, offering a wide array of benefits in combating bacterial infections. It contains two active ingredients: amoxicillin, a penicillin-like antibiotic, and clavulanic acid, a beta-lactamase inhibitor. This synergistic combination allows CLAVAM XR to effectively target and eradicate bacteria that may have developed resistance to amoxicillin alone. One of the primary benefits of CLAVAM XR is its broad-spectrum activity. It is effective against a wide range of bacteria, including many common causes of respiratory tract infections such as pneumonia, bronchitis, and sinusitis. It is also frequently prescribed for urinary tract infections (UTIs), skin and soft tissue infections, and even some dental infections.
  • The inclusion of clavulanic acid is crucial because it inhibits beta-lactamase, an enzyme produced by some bacteria that can inactivate amoxicillin. By preventing this inactivation, clavulanic acid ensures that amoxicillin remains effective, even against resistant strains of bacteria. This makes CLAVAM XR a valuable option when other antibiotics may have failed. Furthermore, CLAVAM XR is often prescribed when a bacterial infection is suspected but the specific type of bacteria is not yet known. Its broad-spectrum activity allows it to start working against a wide range of potential pathogens while awaiting the results of laboratory tests. This can be particularly important in cases where rapid treatment is necessary to prevent the infection from worsening.
  • Another significant benefit of CLAVAM XR is its convenient extended-release (XR) formulation. This means that the medication is released slowly into the body over a longer period, allowing for less frequent dosing compared to immediate-release formulations. This can improve patient compliance and make it easier to adhere to the prescribed treatment regimen. Patients generally need to take CLAVAM XR only twice daily, as directed by their healthcare provider. CLAVAM XR helps to reduce the severity and duration of bacterial infections, leading to faster recovery and improved overall health. By effectively eliminating the infection, it helps alleviate symptoms such as fever, pain, inflammation, and discomfort associated with the infection. This allows patients to return to their normal activities more quickly.
  • In summary, CLAVAM XR Tablet 10'S offers a multifaceted approach to treating bacterial infections. Its broad-spectrum activity, beta-lactamase inhibition, and extended-release formulation make it a valuable and convenient treatment option for a wide range of infections. It is important to note that CLAVAM XR should only be taken under the guidance and prescription of a healthcare professional. They will determine the appropriate dosage and duration of treatment based on the individual patient's condition and the specific type of infection. This ensures that the medication is used safely and effectively to achieve the best possible outcome.

How to use CLAVAM XR TABLET 10'SArrow

  • CLAVAM XR Tablet 10'S is an extended-release medication, meaning it releases the medicine slowly into your system over a longer period. This helps maintain a consistent level of the drug in your body. It's crucial to follow your doctor's instructions carefully regarding dosage and timing. Typically, it is prescribed to be taken twice daily, every 12 hours, or as directed by your physician. Always swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can disrupt the extended-release mechanism and lead to a rapid release of the drug, potentially causing side effects or reducing its effectiveness.
  • This medication is best taken at the start of a meal to improve absorption and reduce the risk of stomach upset. If you experience nausea, taking it with food can help alleviate this. It's important to maintain consistent timing when taking CLAVAM XR. Set a reminder if needed, to avoid missing doses. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Complete the full course of treatment, even if you start feeling better after a few days. Stopping the medication prematurely can allow the infection to persist and may lead to antibiotic resistance. If your symptoms worsen or do not improve after a few days, contact your doctor. It's also essential to inform your doctor about any other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid potential drug interactions. Store CLAVAM XR tablets in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Quick Tips for CLAVAM XR TABLET 10'SArrow

  • Take CLAVAM XR TABLET 10'S as prescribed by your doctor. Do not self-medicate or change the dosage without consulting your physician. This ensures the medication works effectively and minimizes the risk of side effects or antibiotic resistance. Complete the full course of treatment, even if you feel better after a few days. Stopping early can lead to the infection returning or becoming harder to treat.
  • Swallow CLAVAM XR TABLET 10'S whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed in your body, potentially altering its effectiveness. Taking it with food can help reduce stomach upset. CLAVAM XR is designed for extended release, so ensure it is taken as intended for optimal results.
  • Inform your doctor about all medications, supplements, and herbal products you are currently taking before starting CLAVAM XR TABLET 10'S. Drug interactions can occur, affecting the effectiveness of CLAVAM XR or increasing the risk of side effects. Include over-the-counter medications as well. Discuss any allergies you have, especially to penicillin or cephalosporin antibiotics, to avoid allergic reactions.
  • If you experience side effects such as nausea, vomiting, diarrhea, or abdominal pain while taking CLAVAM XR TABLET 10'S, consult your doctor. These symptoms are usually mild, but persistent or severe side effects should be addressed promptly. Stay hydrated by drinking plenty of fluids to help manage diarrhea and maintain overall health during treatment. Report any unusual symptoms immediately.
  • Store CLAVAM XR TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective and safe. Do not use the medication if it has expired or shows signs of damage. Dispose of expired or unused medication properly, following local guidelines for pharmaceutical waste disposal.

Food Interactions with CLAVAM XR TABLET 10'SArrow

  • CLAVAM XR TABLET 10'S is better absorbed when taken at the start of a meal. This helps to reduce stomach upset and improve the effectiveness of the medicine. Avoid taking it on an empty stomach.
  • Dairy products like milk and cheese might affect the absorption of CLAVAM XR TABLET 10'S. It is advisable to maintain a gap of at least 1-2 hours between consuming dairy and taking this medication.
  • While taking CLAVAM XR TABLET 10'S, stay hydrated by drinking plenty of water. This helps in better drug absorption and reduces the chances of side effects.

FAQs

What is Clavam XR Tablet 10'S?Arrow

Clavam XR Tablet 10'S is a combination medicine containing Amoxicillin and Clavulanic acid. It is an antibiotic used to treat various bacterial infections.

What is Clavam XR Tablet 10'S used for?Arrow

It is used to treat bacterial infections such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, and dental infections.

How does Clavam XR Tablet 10'S work?Arrow

Amoxicillin inhibits the growth of bacteria, while Clavulanic acid prevents Amoxicillin from being inactivated, making the medicine more effective against bacterial infections.

What are the common side effects of Clavam XR Tablet 10'S?Arrow

Common side effects may include nausea, vomiting, diarrhea, and stomach pain.

Is Clavam XR Tablet 10'S safe during pregnancy?Arrow

Consult your doctor before using this medicine during pregnancy.

Is Clavam XR Tablet 10'S safe during breastfeeding?Arrow

Consult your doctor before using this medicine during breastfeeding.

Can Clavam XR Tablet 10'S interact with other medications?Arrow

Yes, it can interact with certain medications. Inform your doctor about all the medicines you are taking.

What is the dosage of Clavam XR Tablet 10'S?Arrow

The dosage depends on your condition and doctor's instructions. Please follow your doctor's instructions.

Can Clavam XR Tablet 10'S be taken with or without food?Arrow

It is recommended to take it with food to avoid stomach upset.

How to store Clavam XR Tablet 10'S?Arrow

Store it at room temperature, away from direct sunlight and moisture.

Does Clavam XR Tablet 10'S cause drowsiness?Arrow

It does not usually cause drowsiness, but if you feel dizzy, avoid driving or operating machinery.

Can I drink alcohol with Clavam XR Tablet 10'S?Arrow

Drinking alcohol can increase the risk of side effects, so it is advisable to avoid it.

What happens if I miss a dose of Clavam XR Tablet 10'S?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Is Clavam XR Tablet 10'S effective for all types of infections?Arrow

It is only effective for bacterial infections. It will not work for viral infections like the common cold or flu.

Can Clavam XR Tablet 10'S be used interchangeably with other Amoxicillin/Clavulanate products?Arrow

Different products may have different dosages of Amoxicillin and Clavulanate. Always consult your doctor or pharmacist to determine which product is most suitable for you.

References

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DrugBank: Amoxicillin

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DrugBank: Clavulanic Acid

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National Center for Biotechnology Information (NCBI): 'Amoxicillin/clavulanate versus piperacillin/tazobactam as empirical therapy for sepsis'

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National Center for Biotechnology Information (NCBI): 'Updates on amoxicillin/clavulanate resistance'

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U.S. Food & Drug Administration (FDA): Augmentin (amoxicillin/clavulanate potassium) prescribing information

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Marketer / Manufacturer Details

ALKEM LABORATORIES LIMITED

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India

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