CLENORUSH GEL 15 ML

How CLENORUSH GEL 15 ML Works

• CLENORUSH GEL 15 ML is a topical medication formulated to address acne vulgaris. Its effectiveness stems from the synergistic action of its active ingredients: Clindamycin and Nicotinamide. Clindamycin, an antibiotic, targets the bacteria primarily responsible for acne, while Nicotinamide, a form of Vitamin B3, possesses anti-inflammatory properties and helps to improve the skin's barrier function.
• Clindamycin operates by inhibiting bacterial protein synthesis. Specifically, it binds to the 23S ribosomal RNA of susceptible bacteria, preventing the attachment of tRNA and thus halting the elongation of the peptide chain. This action effectively stops the growth and multiplication of *Cutibacterium acnes* (formerly *Propionibacterium acnes*), the bacteria that colonizes hair follicles and contributes to the formation of acne lesions. By reducing the bacterial population, Clindamycin helps to diminish inflammation and prevent new acne breakouts.
• Nicotinamide, also known as Niacinamide, contributes to the therapeutic effect through several mechanisms. Firstly, it exhibits anti-inflammatory properties, which help to soothe irritated skin and reduce the redness and swelling associated with acne lesions. Secondly, Nicotinamide enhances the skin's barrier function by promoting the synthesis of ceramides, cholesterol, and fatty acids, which are essential components of the stratum corneum (the outermost layer of the skin). A stronger skin barrier helps to prevent moisture loss, protect against external irritants, and reduce the severity of acne. Furthermore, Nicotinamide has been shown to regulate sebum production, potentially reducing the oiliness of the skin, a contributing factor to acne development.
• The combined effect of Clindamycin and Nicotinamide in CLENORUSH GEL 15 ML offers a multi-pronged approach to acne treatment. Clindamycin directly combats the bacterial infection, while Nicotinamide addresses inflammation, improves skin barrier function, and may help control sebum production. This dual action can lead to a reduction in the number and severity of acne lesions, resulting in clearer and healthier-looking skin. The gel formulation allows for targeted application to affected areas, minimizing systemic absorption and potential side effects. Regular and consistent use, as directed by a healthcare professional, is crucial for achieving optimal results.
• In summary, CLENORUSH GEL 15 ML works by leveraging the antibacterial power of Clindamycin to eliminate acne-causing bacteria and the anti-inflammatory and skin-strengthening properties of Nicotinamide. This combination helps to reduce inflammation, promote healing, and prevent future breakouts, ultimately leading to improved skin clarity and overall skin health.

Like all medications, Clenorush Gel can cause side effects, although not everyone experiences them. Common side effects may include skin irritation, redness, itching, burning sensation, or dryness at the application site. Some individuals might experience allergic reactions such as rash, hives, or swelling. Less common side effects could involve changes in skin pigmentation or increased sensitivity to sunlight. If any of these side effects persist or worsen, discontinue use and consult your doctor or pharmacist immediately. This is not an exhaustive list, and other side effects may occur. Always read the label and follow the usage instructions carefully.

• Since this medication is usually applied when needed, you are not likely to miss a dose. However, if you forget to apply the gel, apply it as soon as you remember. Do not apply a double dose to make up for the missed one.

• Keep CLENORUSH GEL 15ML away from the reach of children and pets.
• Store CLENORUSH GEL 15ML at room temperature.

• **Cleanse the Area:** Before applying Clenorush Gel, gently wash and dry the affected skin area. This helps remove any dirt, oil, or debris, allowing the gel to penetrate effectively. Use a mild, non-irritating cleanser to avoid further aggravation.
• **Apply a Thin Layer:** Squeeze a small amount of Clenorush Gel onto your fingertip and apply a thin, even layer over the affected area. Avoid using excessive amounts, as a thin layer is sufficient for optimal absorption and effectiveness. Gently massage the gel into the skin until it is fully absorbed.
• **Use Regularly:** For best results, use Clenorush Gel as directed by your healthcare provider, typically twice daily – once in the morning and once before bedtime. Consistent application is crucial for maintaining the therapeutic effect and promoting healing. Missing applications may delay the desired outcome.
• **Avoid Contact with Eyes and Mucous Membranes:** Be careful not to get Clenorush Gel in your eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with plenty of water. If irritation persists, seek medical attention immediately. This gel is intended for external use only.
• **Monitor for Irritation:** While Clenorush Gel is generally well-tolerated, some individuals may experience mild irritation, redness, or dryness. If you notice any adverse reactions, discontinue use and consult your doctor. They may recommend adjusting the frequency of application or using a moisturizer to alleviate dryness.
• **Store Properly:** Store Clenorush Gel in a cool, dry place, away from direct sunlight and heat. Keep the tube tightly closed when not in use to prevent contamination and maintain the gel's efficacy. Ensure it is out of reach of children.
• **Be Patient:** Improvement may not be immediate. It may take several weeks of consistent use to see noticeable results. Continue using Clenorush Gel as directed, even if you don't see immediate improvement. If your condition worsens or does not improve after a reasonable period, consult your healthcare provider.
• **Combine with Healthy Habits:** Maximize the effectiveness of Clenorush Gel by incorporating healthy skincare habits into your routine. This includes staying hydrated, eating a balanced diet, getting enough sleep, and avoiding harsh chemicals or irritants on your skin. A holistic approach can support healing and overall skin health.

• While using CLENORUSH GEL 15 ML, specific food interactions are unlikely since it is a topical medication applied to the skin. However, it is always a good practice to inform your doctor about all medications, including topical treatments, you are using. Maintain a balanced diet for overall health, which can indirectly support skin health.