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Composition
Content Reviewed By:
Dr. Rajesh Sharma
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects include:

Dependence, Withdrawal, and Misuse
Use under strict medical supervisionCloba 5 contains clobazam, a benzodiazepine that can cause tolerance, physical dependence, and withdrawal symptoms, particularly with prolonged use or higher doses.
Yes, CLOBA 5MG TABLET 15'S can be habit forming if used for a long time. The risk of dependence increases with dose and duration of treatment; it is also greater in patients with a history of alcohol or drug abuse. Therefore, the duration of treatment is generally as short as possible.
Yes, CLOBA 5MG TABLET 15'S can make you sleepy. It usually begins within the first month of treatment and may diminish with continued treatment.
CLOBA 5MG TABLET 15'S is a fast-acting medicine, which means that it quickly gets absorbed from the bloodstream. CLOBA 5MG TABLET 15'S reaches its highest blood levels within half an hour to 4 hours after the dose is taken.
No, CLOBA 5MG TABLET 15'S and clonazepam are not the same medicines but belong to the same class of drugs known as benzodiazepines.
Withdrawal syndrome may develop at any time up to 3 weeks after stopping CLOBA 5MG TABLET 15'S. Withdrawal signs may last anywhere from 4 weeks to a year or more.
No, do not stop taking CLOBA 5MG TABLET 15'S even if you are feeling well, unless your doctor tells you to. Suddenly stopping CLOBA 5MG TABLET 15'S may cause unwanted effects known as withdrawal symptoms. To prevent this, the dose of clobazam needs to be reduced gradually before completely stopping it. Therefore, it is important that you consult your doctor first.
Taking more than the recommended doses of CLOBA 5MG TABLET 15'S can affect in different ways, and the patient should seek immediate medical help. In mild cases, it may cause symptoms such as drowsiness, mental confusion, and tiredness. Whereas, in more serious cases, the symptoms may include the complete loss of control of bodily movements, decreased muscle tone, low blood pressure, respiratory depression, coma in rare cases, and death in very rare cases.
Generally, the use of CLOBA 5MG TABLET 15'S does not cause a decrease in the blood pressure, but taking more than the recommended doses of CLOBA 5MG TABLET 15'S may cause a fall in the blood pressure
CLOBA 5MG TABLET 15'S may cause tiredness along with muscle weakness. In case you experience tiredness or if tiredness persists for a long time, then you should consult your doctor.
No, CLOBA 5MG TABLET 15'S dose not cause depression, but it can cause recurrence of pre-existing depression.
Cloba 5 is a prescription antiepileptic medicine that contains clobazam 5 mg as its active ingredient. Clobazam is a benzodiazepine derivative used mainly as adjunctive therapy in the management of various seizure disorders, including Lennox–Gastaut syndrome and other forms of epilepsy that are not adequately controlled with standard antiepileptic drugs alone.
Cloba 5 works by enhancing the effect of gamma‑aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. Clobazam binds to specific benzodiazepine sites on the GABA-A receptor complex, increasing the frequency of chloride channel opening in response to GABA. This leads to increased neuronal inhibition, reduced excitability of brain cells, and a consequent reduction in the frequency and severity of seizures.
Cloba 5 is commonly prescribed as add‑on therapy for various types of epilepsy, particularly for seizures associated with Lennox–Gastaut syndrome, focal seizures, and certain generalized seizures that are not adequately controlled by other antiepileptic medicines. It may also be used in other seizure disorders at the discretion of a specialist. It is not intended for routine use as a first‑line treatment for anxiety or insomnia in most clinical settings.
No. Cloba 5 is a prescription‑only medicine that must be used under the supervision of a qualified healthcare professional. Because clobazam is a benzodiazepine with potential for tolerance, dependence, and withdrawal, the dose and duration of therapy must be individualized and regularly reviewed by a doctor. You should not start, stop, or change the dose on your own, and you should not share this medicine with anyone else.
Common side effects of Cloba 5 include drowsiness, fatigue, dizziness, slowed thinking, impaired coordination, and unsteadiness. Some patients may experience headache, blurred vision, drooling, constipation, nausea, decreased appetite or increased appetite, and behavioral changes such as irritability, agitation, or restlessness, especially in children. These effects are often dose‑related and may lessen as the body adjusts, but persistent or troublesome symptoms should be discussed with a doctor.
Serious but less common risks of Cloba 5 include severe sedation, respiratory depression (slow or shallow breathing), severe skin reactions, significant mood changes, suicidal thoughts or behavior, and paradoxical reactions such as increased anxiety, aggression, or insomnia. Long‑term use can lead to tolerance and physical dependence, and abrupt discontinuation may trigger withdrawal symptoms or worsening seizures. Any signs of difficulty breathing, severe rash, marked confusion, or suicidal ideation require urgent medical attention.
Alcohol should generally be avoided while taking Cloba 5. Both alcohol and clobazam depress the central nervous system, and their combined use can lead to excessive drowsiness, impaired coordination, confusion, and an increased risk of accidents or respiratory depression. Even small amounts of alcohol may significantly enhance these effects in some individuals. If you have questions about alcohol use, discuss them with your doctor before starting treatment.
Use of Cloba 5 during pregnancy requires careful risk–benefit assessment by a specialist. Benzodiazepines, including clobazam, may be associated with risks such as neonatal respiratory depression, floppy infant syndrome, and withdrawal symptoms in the newborn if used, particularly in late pregnancy or at higher doses. However, uncontrolled seizures also pose serious risks to both mother and fetus. Do not stop or change your antiepileptic treatment if you become pregnant without consulting your neurologist or obstetrician.
If you miss a dose of Cloba 5, follow the instructions provided by your doctor or the patient information leaflet. In general, if it is close to the time of your next scheduled dose, you should skip the missed dose and take the next one at the usual time. Do not take a double dose to make up for a missed dose, as this may increase the risk of side effects such as excessive sedation or dizziness. If you are unsure what to do, contact your doctor or pharmacist for advice.
Yes. Cloba 5 can cause drowsiness, slowed reaction time, dizziness, and impaired coordination, particularly when treatment is started, when the dose is increased, or when taken with other central nervous system depressants. These effects can significantly impair your ability to drive, operate machinery, or perform tasks requiring alertness. You should not drive or engage in hazardous activities until you know how Cloba 5 affects you and your doctor confirms that it is safe to do so under local regulations.
Cloba 5 should not be stopped suddenly, especially after long‑term use or at higher total daily doses. Abrupt discontinuation can lead to withdrawal symptoms such as anxiety, insomnia, tremor, irritability, and, importantly, rebound or worsening seizures, including the risk of status epilepticus. If your doctor decides that clobazam should be reduced or discontinued, the dose will usually be tapered gradually over a period of time while monitoring your seizure control and overall clinical status.
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INTAS PHARMACEUTICALS LIMITED
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India
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