CLOTNINE 600IU INJECTION
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CLOTNINE 600IU INJECTION
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CLOTNINE 600IU INJECTION

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CLOTNINE 600IU INJECTION

By HEMARUS THERAPEUTICS LTD

MRP

13000

₹9880

24 % OFF

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Composition

Product DetailsArrow

About CLOTNINE 600IU INJECTION

  • CLOTNINE 600IU INJECTION contains factor IX as an active component. It is primarily used in individuals with hemophilia B (a deficiency of factor IX) to prevent and treat bleeding episodes. In certain instances, individuals with hemophilia A (caused by a deficiency of factor VIII) who have developed inhibitors (antibodies) against factor VIII may find CLOTNINE 600IU INJECTION a suitable alternative when standard treatment becomes ineffective. The medication can be administered before, during, and after surgical procedures to minimize the risk of excessive bleeding. It is also employed as a preventive measure in some hemophilia B patients to maintain a baseline level of factor IX in their bloodstream, thereby reducing the likelihood of spontaneous bleeding, especially in joints and muscles. Furthermore, CLOTNINE 600IU INJECTION can be given after traumatic injuries or accidents to control bleeding and prevent further complications.
  • Beyond hemophilia, CLOTNINE 600IU INJECTION may be considered in rare cases for treating other bleeding disorders or conditions associated with factor IX deficiency, such as acquired hemophilia. It's crucial to remember that CLOTNINE 600IU INJECTION is not suitable for everyone. It is contraindicated in individuals with a known allergy or hypersensitivity to the product or any of its components. Additionally, it is not appropriate for individuals with Disseminated Intravascular Coagulation (DIC), a complex bleeding disorder characterized by abnormal clotting and bleeding. Patients with severe liver disease may not respond favorably to CLOTNINE 600IU INJECTION, and a careful evaluation of the risks and benefits is necessary before administration.
  • While CLOTNINE 600IU INJECTION is often used in pediatric patients with hemophilia B, the dosage and administration must be carefully adjusted based on the child's age and weight, with close monitoring throughout the treatment. In older adults with hemophilia B, CLOTNINE 600IU INJECTION replacement therapy can be a safe and effective treatment option. However, it's important to tailor dosing and treatment plans to each individual's specific health status and medical history to ensure the best possible outcome and minimize potential risks. Always consult with a healthcare professional for personalized medical advice.

Uses of CLOTNINE 600IU INJECTION

  • CLOTNINE 600IU INJECTION is used in the treatment of hemophilia B, a genetic bleeding disorder caused by a deficiency of factor IX.
  • Prophylactic treatment to prevent bleeding episodes in patients with hemophilia B.
  • Management of acute bleeding episodes in individuals with factor IX deficiency, helping to control and stop the bleeding.
  • To control bleeding during and after surgical procedures in patients with hemophilia B, ensuring better surgical outcomes.
  • Used in cases of trauma and injuries to manage bleeding and prevent complications in individuals with factor IX deficiency.
  • As an alternative treatment option for hemophilia A patients who have developed inhibitors to factor VIII.
  • Management of other bleeding disorders related to factor IX deficiencies or other coagulation abnormalities.
  • Used in pediatric patients with hemophilia B to prevent and manage bleeding episodes and improve their quality of life.

Side Effects of CLOTNINE 600IU INJECTIONArrow

CLOTNINE 600IU INJECTION, like all medications, can cause side effects, although not everyone will experience them.

  • Allergic reactions
  • Development of inhibitors
  • Thrombosis (blood clots)
  • Hepatitis transmission
  • Liver complications
  • Localized reactions

Safety Advice for CLOTNINE 600IU INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

The use of CLOTNINE 600IU INJECTION therapy during pregnancy should be discussed with a healthcare provider. The safety and potential risks to the developing fetus should be carefully considered, and treatment options should be weighed.

Dosage of CLOTNINE 600IU INJECTIONArrow

  • Replacement therapy with CLOTNINE 600IU INJECTION can be administered either through intravenous (IV) infusion or direct intravenous injection. The optimal method for administration is determined by several factors, ensuring the best possible outcome for the patient.
  • The selection of the appropriate administration route hinges on the specific formulation of CLOTNINE 600IU INJECTION being used. Different products may have different requirements or recommendations for how they should be given.
  • Patient-specific factors also play a crucial role. The patient's age, for example, can influence the choice, as can the severity of their hemophilia B. In cases of severe deficiency, a faster infusion rate may be necessary, potentially favoring direct IV injection.
  • Moreover, individual patient preferences and venous access should be considered. Some patients may find one method more comfortable or convenient than the other. Ultimately, the decision should be made in consultation with a healthcare professional who can assess all relevant factors and provide personalized guidance.

How to store CLOTNINE 600IU INJECTION?Arrow

  • Keep CLOTNINE 600IU INJ away from the reach of children and pets.
  • Store CLOTNINE 600IU INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of CLOTNINE 600IU INJECTIONArrow

  • Once CLOTNINE 600IU INJECTION is administered intravenously, it seamlessly integrates with the patient's bloodstream. This allows the medication to actively participate in the intricate process of blood coagulation. When an injury occurs or a bleeding episode begins, CLOTNINE 600IU INJECTION plays a crucial role in initiating and accelerating the formation of a stable and effective blood clot. It achieves this by activating a series of other coagulation factors in a carefully orchestrated sequence.
  • This activation cascade is essential for hemostasis, the body's natural mechanism to stop bleeding. CLOTNINE 600IU INJECTION ensures that the coagulation process proceeds efficiently, leading to the rapid generation of fibrin, the protein that forms the mesh-like structure of a blood clot. The resulting clot effectively seals the damaged blood vessel, preventing further blood loss and promoting the healing process.
  • By facilitating the rapid formation of a stable blood clot, CLOTNINE 600IU INJECTION helps to minimize the duration and severity of bleeding episodes. This is particularly important for individuals with clotting disorders or those undergoing surgical procedures where the risk of bleeding is elevated. The medication's targeted action on the coagulation cascade makes it a valuable tool in managing and preventing excessive bleeding.

How to use CLOTNINE 600IU INJECTIONArrow

  • Replacement therapy with CLOTNINE 600IU INJECTION can be administered through either intravenous (IV) infusion or direct intravenous injection. The optimal method for administering CLOTNINE 600IU INJECTION is determined by several factors, including the specific formulation of the product being used, the patient's age and overall health, the severity of their hemophilia B, and, to some extent, their individual preferences and venous access.
  • Intravenous infusion typically involves a slower, more controlled delivery of the medication over a specified period, often ranging from several minutes to an hour. This method may be preferred for larger doses or when administering CLOTNINE 600IU INJECTION to younger children or individuals with compromised venous access.
  • Direct intravenous injection, on the other hand, involves a faster, more direct administration of the medication into a vein. This method may be suitable for smaller doses or when a more rapid increase in factor IX levels is desired. Regardless of the chosen method, it is crucial that the administration be performed by a qualified healthcare professional using appropriate sterile techniques to minimize the risk of infection or other complications.
  • The healthcare provider will carefully monitor the patient during and after the administration of CLOTNINE 600IU INJECTION to assess their response to the treatment and to detect any potential adverse reactions. Regular monitoring of factor IX levels is also essential to ensure that the patient is receiving an adequate dose and to guide any necessary adjustments to the treatment regimen.

FAQs

How often is CLOTNINE 600IU INJECTION replacement therapy required?Arrow

The frequency of CLOTNINE 600IU INJECTION replacement therapy depends on the severity of hemophilia B and the treatment plan developed by healthcare providers. Some individuals may require regular prophylactic treatment, while others only need it when experiencing bleeding episodes.

Are there any side effects or risks associated with CLOTNINE 600IU INJECTION replacement therapy?Arrow

While CLOTNINE 600IU INJECTION replacement therapy is generally safe and well-tolerated, there can be risks, including allergic reactions, inhibitor development, and thrombosis (blood clot formation). Patients should discuss potential risks with their healthcare providers.

What should I do in case of a bleeding emergency while on CLOTNINE 600IU INJECTION therapy?Arrow

Individuals on CLOTNINE 600IU INJECTION therapy should contact their healthcare provider or seek immediate medical attention if a bleeding emergency occurs. In some cases, they may be trained to administer CLOTNINE 600IU INJECTION at home for quick response to bleeding episodes.

Can CLOTNINE 600IU INJECTION replacement therapy be self-administered at home?Arrow

Some individuals with hemophilia B are trained to self-administer CLOTNINE 600IU INJECTION at home. This can provide convenience and rapid access to treatment when needed, especially for prophylactic regimens.

Are there any dietary restrictions while on CLOTNINE 600IU INJECTION therapy?Arrow

There are usually no specific dietary restrictions while on CLOTNINE 600IU INJECTION therapy. However, maintaining a balanced diet and staying hydrated can support overall health and well-being for individuals with hemophilia B.

Is participating in sports and physical activities possible while on CLOTNINE 600IU INJECTION therapy?Arrow

With proper management and treatment, individuals with hemophilia B can participate in sports and physical activities. They should work closely with their healthcare providers to develop a safe exercise regimen and take precautions to prevent injuries.

Does CLOTNINE 600IU INJECTION interact with other drugs?Arrow

There are no known significant interactions of CLOTNINE 600IU INJECTION with other drugs.

What precautions should I take while using CLOTNINE 600IU INJECTION?Arrow

Patient should be aware of the potential for allergic reactions and promptly report any signs, such as hives or difficulty breathing. Regular monitoring of CLOTNINE 600IU INJECTION levels is crucial, especially for inhibitor development, as adjustments to the treatment plan may be needed. Patients with liver or kidney conditions should exercise caution, as should those receiving live vaccines, to avoid potential interactions. In surgical or dental procedures, healthcare providers should be informed to make necessary treatment adjustments. Patients should also be mindful of alcohol intake, especially given its impact on liver function, and practice safe driving. An emergency plan for bleeding episodes and access to psychosocial support can further enhance the safety and well-being of individuals with hemophilia B.

What is CLOTNINE 600IU INJECTION made of?Arrow

CLOTNINE 600IU INJECTION is made of Factor IX.

For what diseases is CLOTNINE 600IU INJECTION used to treat?Arrow

CLOTNINE 600IU INJECTION is used to treat diseases related to Cardiology and Hematology.

How often is CLOTNINE 600IU INJECTION replacement therapy required?Arrow

The frequency of CLOTNINE 600IU INJECTION replacement therapy depends on the severity of hemophilia B and the treatment plan developed by healthcare providers. Some individuals may require regular prophylactic treatment, while others only need it when experiencing bleeding episodes.

Are there any side effects or risks associated with CLOTNINE 600IU INJECTION replacement therapy?Arrow

While CLOTNINE 600IU INJECTION replacement therapy is generally safe and well-tolerated, there can be risks, including allergic reactions, inhibitor development, and thrombosis (blood clot formation). Patients should discuss potential risks with their healthcare providers.

What should I do in case of a bleeding emergency while on CLOTNINE 600IU INJECTION therapy?Arrow

Individuals on CLOTNINE 600IU INJECTION therapy should contact their healthcare provider or seek immediate medical attention if a bleeding emergency occurs. In some cases, they may be trained to administer CLOTNINE 600IU INJECTION at home for quick response to bleeding episodes.

Can CLOTNINE 600IU INJECTION replacement therapy be self-administered at home?Arrow

Some individuals with hemophilia B are trained to self-administer CLOTNINE 600IU INJECTION at home. This can provide convenience and rapid access to treatment when needed, especially for prophylactic regimens.

Are there any dietary restrictions while on CLOTNINE 600IU INJECTION therapy?Arrow

There are usually no specific dietary restrictions while on CLOTNINE 600IU INJECTION therapy. However, maintaining a balanced diet and staying hydrated can support overall health and well-being for individuals with hemophilia B.

Is participating in sports and physical activities possible while on CLOTNINE 600IU INJECTION therapy?Arrow

With proper management and treatment, individuals with hemophilia B can participate in sports and physical activities. They should work closely with their healthcare providers to develop a safe exercise regimen and take precautions to prevent injuries.

Does CLOTNINE 600IU INJECTION interact with other drugs?Arrow

There are no known significant interactions of CLOTNINE 600IU INJECTION with other drugs.

What precautions should I take while using CLOTNINE 600IU INJECTION?Arrow

Patient should be aware of the potential for allergic reactions and promptly report any signs, such as hives or difficulty breathing. Regular monitoring of CLOTNINE 600IU INJECTION levels is crucial, especially for inhibitor development, as adjustments to the treatment plan may be needed. Patients with liver or kidney conditions should exercise caution, as should those receiving live vaccines, to avoid potential interactions. In surgical or dental procedures, healthcare providers should be informed to make necessary treatment adjustments. Patients should also be mindful of alcohol intake, especially given its impact on liver function, and practice safe driving. An emergency plan for bleeding episodes and access to psychosocial support can further enhance the safety and well-being of individuals with hemophilia B.

What is CLOTNINE 600IU INJECTION made of?Arrow

CLOTNINE 600IU INJECTION is made of Factor IX.

For what diseases is CLOTNINE 600IU INJECTION used to treat?Arrow

CLOTNINE 600IU INJECTION is used to treat diseases related to Cardiology and Hematology.

References

Book Icon

Octapharma Limited, Electronic Medicines Compendium (EMC)

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NA Orlova et al; Factor IX  for Haemophilia B therapy; Acta Naturae 2012

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T Zögg; Activation mechanisms of coagulation factor IX; Biological Chemistry 2009

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₹9880

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