COMBINASE FT NASAL SPRAY 9.8 GM

How COMBINASE FT NASAL SPRAY 9.8 GM Works

• COMBINASE FT NASAL SPRAY 9.8 GM is a combination medication designed to relieve nasal congestion and other symptoms associated with allergic rhinitis (hay fever) and non-allergic rhinitis. It contains two active ingredients: fluticasone propionate and azelastine hydrochloride. Each component works through a different mechanism to alleviate nasal symptoms.
• Fluticasone propionate is a synthetic corticosteroid with potent anti-inflammatory properties. When sprayed into the nose, fluticasone reduces inflammation in the nasal passages. It achieves this by inhibiting the release of inflammatory mediators such as histamine, cytokines, and leukotrienes from mast cells and other immune cells lining the nasal mucosa. By reducing inflammation, fluticasone effectively decreases nasal congestion, rhinorrhea (runny nose), post-nasal drip, and sneezing. The anti-inflammatory effect also helps to shrink swollen nasal tissues, further improving airflow.
• Azelastine hydrochloride is an antihistamine. It works by blocking the action of histamine, a substance in the body that causes allergy symptoms. When an allergen (like pollen or dust) enters the body, it triggers the release of histamine, which then binds to receptors in the nasal passages, leading to itching, sneezing, and increased mucus production. Azelastine directly blocks these histamine receptors, preventing histamine from binding and thus reducing these allergy symptoms. Azelastine's antihistamine effect is relatively quick, often providing relief within minutes of application.
• The combination of fluticasone and azelastine provides a synergistic effect, addressing nasal allergy symptoms through multiple pathways. Fluticasone tackles the underlying inflammation, while azelastine directly blocks the histamine response. This dual-action approach often provides more comprehensive relief than either medication used alone. The spray is applied directly to the nasal passages, delivering the medication where it is needed most and minimizing systemic absorption. This targeted delivery helps to reduce the risk of systemic side effects compared to oral medications.
• The effectiveness of COMBINASE FT NASAL SPRAY 9.8 GM relies on consistent and proper use. The medication should be used as directed by a healthcare professional, typically with a specific number of sprays in each nostril, once or twice daily. Regular use helps to maintain the anti-inflammatory and antihistamine effects, providing continuous relief from nasal allergy symptoms. It's important to note that while some relief may be noticed shortly after the initial use, the full benefits of fluticasone may take several days to become apparent.

Common side effects of COMBINASE FT NASAL SPRAY may include: Nasal discomfort, nosebleeds, headache, altered sense of taste, and pharyngitis. Less common but more serious side effects may include: Allergic reactions (rash, itching, swelling), nasal septum perforation, glaucoma, cataracts, and increased intraocular pressure. Some patients might experience cough, hoarseness, or fungal infection in the nose or throat. Rarely, systemic corticosteroid effects such as adrenal suppression or growth retardation in children may occur. Consult your doctor if side effects persist or worsen.

• If you miss a dose of COMBINASE FT Nasal Spray, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one.

• Keep COMBINASE FT NASAL SPRAY 9.8GM away from the reach of children and pets.
• Store COMBINASE FT NASAL SPRAY 9.8GM at room temperature.

• Prime the pump before initial use: Before using COMBINASE FT Nasal Spray for the first time, prime the pump by shaking the bottle well and then spraying it into the air away from your face until a fine mist appears. Re-priming is also necessary if the spray hasn't been used for more than a week. This ensures you receive the correct dose.
• Shake well before each use: Always shake the COMBINASE FT Nasal Spray well immediately before each use. This helps to properly mix the medication and ensures that each spray delivers a consistent and accurate dose. Neglecting to shake the bottle can result in inconsistent dosing and reduced effectiveness.
• Use consistently as prescribed: For best results, use COMBINASE FT Nasal Spray exactly as your doctor prescribes. This usually involves a specific number of sprays in each nostril, once or twice daily. Consistent use, even when you feel better, is important to manage your symptoms and prevent them from returning. Do not exceed the recommended dosage without consulting your healthcare provider.
• Proper administration technique: To administer the spray correctly, gently blow your nose to clear your nostrils. Tilt your head slightly forward and insert the nozzle into one nostril, aiming towards the outer wall of your nose. While sniffing gently, press the pump to release the spray. Repeat in the other nostril. Avoid spraying directly onto the nasal septum (the middle part of your nose) to prevent irritation or bleeding.
• Clean the nozzle regularly: To prevent clogging and maintain hygiene, clean the nozzle of the COMBINASE FT Nasal Spray regularly. After each use, wipe the nozzle with a clean, dry tissue. If the nozzle becomes blocked, remove it and rinse it with warm water, then allow it to air dry completely before reattaching it to the bottle. Never use a pin or sharp object to clear the nozzle.
• Store properly: Store COMBINASE FT Nasal Spray in an upright position at room temperature, away from direct sunlight, heat, and moisture. Keep the bottle tightly closed when not in use. Proper storage helps maintain the medication's effectiveness and prevents degradation. Keep out of reach of children.

• COMBINASE FT NASAL SPRAY 9.8 GM is generally considered safe to use with food. There are no known significant interactions between this nasal spray and specific food items. You can use it without regard to meals. However, if you experience any unusual discomfort or side effects, consult your doctor.