COMBISAFE TABLET 10'S

How COMBISAFE TABLET 10'S Works

• COMBISAFE TABLET 10'S is a combination medication designed to provide relief from pain and fever. It contains two active ingredients: Paracetamol and Ibuprofen, each working through distinct mechanisms to alleviate discomfort.
• Paracetamol, also known as acetaminophen, primarily acts by inhibiting the production of prostaglandins in the brain. Prostaglandins are chemicals that contribute to pain and fever. By reducing their levels, Paracetamol helps to lower body temperature and reduce pain sensations. It is particularly effective for headaches, muscle aches, and fever associated with common illnesses like colds and flu. Paracetamol is gentle on the stomach and is generally well-tolerated.
• Ibuprofen belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting cyclooxygenase (COX) enzymes, which are responsible for producing prostaglandins throughout the body. By blocking COX enzymes, Ibuprofen reduces the production of prostaglandins at the site of inflammation. This action helps to alleviate pain, reduce inflammation, and lower fever. Ibuprofen is effective for conditions such as arthritis, menstrual cramps, and pain associated with injuries.
• The combination of Paracetamol and Ibuprofen in COMBISAFE TABLET 10'S provides a synergistic effect, meaning that the two drugs work together to provide greater pain relief and fever reduction than either drug could achieve alone. This combination is particularly useful for managing moderate to severe pain, where a single analgesic may not be sufficient.
• When you take COMBISAFE TABLET 10'S, both Paracetamol and Ibuprofen are absorbed into the bloodstream. Paracetamol quickly targets the brain to reduce fever and pain signals, while Ibuprofen works peripherally to reduce inflammation and pain at the source. This dual action helps to provide comprehensive relief from various types of pain and discomfort. Always follow the recommended dosage and consult with a healthcare professional if you have any concerns or underlying health conditions.
• In summary, COMBISAFE TABLET 10'S provides effective relief through the combined action of Paracetamol, which reduces pain and fever by targeting prostaglandin production in the brain, and Ibuprofen, which reduces inflammation and pain by blocking COX enzymes throughout the body. This synergistic effect makes it a valuable option for managing a wide range of painful conditions.

Like all medicines, CombiSafe Tablet can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Nausea * Vomiting * Heartburn * Stomach pain * Diarrhea * Constipation * Headache * Dizziness * Drowsiness * Fatigue * Dry mouth * Increased sweating **Uncommon Side Effects (may affect up to 1 in 100 people):** * Skin rash * Itching * Hives * Anxiety * Insomnia * Nervousness * Tremors * Blurred vision * Tinnitus (ringing in the ears) * Fluid retention (edema) * Increased blood pressure **Rare Side Effects (may affect up to 1 in 1,000 people):** * Allergic reaction (swelling of the face, lips, tongue, or throat; difficulty breathing) * Liver problems (yellowing of the skin or eyes, dark urine, pale stools) * Kidney problems (decreased urination, swelling of the ankles or feet) * Blood disorders (unexplained bruising or bleeding, frequent infections) * Severe skin reactions (blistering, peeling, or widespread rash) * Depression * Confusion * Hallucinations **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Severe allergic reaction (anaphylaxis) * Liver failure * Kidney failure **Important Note:** This is not an exhaustive list. If you experience any unusual or concerning symptoms while taking CombiSafe Tablet, stop taking the medicine and consult your doctor immediately.

• If you miss a dose of COMBISAFE TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep COMBISAFE TAB 1X10 away from the reach of children and pets.
• Store COMBISAFE TAB 1X10 at room temperature.

• CombisafE Tablet is a combination medicine used for relieving mild to moderate pain, such as headache, migraine, toothache, period pain, and fever. It contains paracetamol, an analgesic and antipyretic, and ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID). Always follow your doctor's instructions precisely when taking CombisafE. This includes dosage and duration of treatment to maximize benefits and minimize risks.
• To minimize the risk of stomach upset, take CombisafE Tablet with food or milk. This helps to buffer the medication's effect on your stomach lining. If you experience persistent stomach pain, heartburn, or other gastrointestinal issues, consult your doctor immediately. Do not lie down immediately after taking medicine.
• Be aware of potential side effects. Common side effects of CombisafE include nausea, vomiting, heartburn, and diarrhea. Serious side effects are rare but can include allergic reactions (rash, itching, swelling), stomach ulcers, bleeding, or liver/kidney problems. Seek immediate medical attention if you experience any severe or persistent side effects.
• Avoid combining CombisafE with other medications without consulting your doctor or pharmacist. Paracetamol and ibuprofen can interact with various drugs, including blood thinners (warfarin), aspirin, and certain antidepressants. Interactions can increase the risk of side effects or reduce the effectiveness of either medication.
• If you have any pre-existing medical conditions, such as asthma, high blood pressure, heart disease, kidney problems, or liver problems, inform your doctor before taking CombisafE. These conditions can increase your risk of experiencing side effects from the medication, and your doctor may need to adjust your dosage accordingly. Regular monitoring may be required.

• COMBISAFE TABLET 10'S can be taken with or without food. However, if you experience stomach upset, it is recommended to take it with food to minimize irritation. Avoid excessive consumption of alcohol while taking this medication, as it may increase the risk of liver damage or other side effects. Always follow your doctor's instructions regarding diet and medication.