COMBISALIC CREAM 20 GM

How COMBISALIC CREAM 20 GM Works

• COMBISALIC CREAM 20 GM is a topical medication combining two active ingredients: clobetasol propionate and salicylic acid. Each component addresses different aspects of skin conditions like psoriasis and eczema, providing comprehensive relief. Clobetasol propionate is a highly potent corticosteroid that reduces inflammation, itching, and redness by suppressing the immune system's response in the skin. It works by binding to specific receptors inside skin cells, which then inhibits the production of inflammatory substances such as prostaglandins and leukotrienes. This action leads to a decrease in blood vessel dilation, reduced swelling, and diminished immune cell activity in the affected area.
• Salicylic acid, on the other hand, is a keratolytic agent. It works by softening keratin, a protein that forms a major part of the skin structure. This softening effect helps to loosen and shed the outer layer of skin (stratum corneum), reducing scaling and promoting the penetration of clobetasol propionate. By removing the dead skin cells, salicylic acid also helps to unclog pores and prevent the formation of comedones (blackheads and whiteheads). This exfoliating action is particularly beneficial in conditions like psoriasis, where there is an overproduction of skin cells.
• The combination of these two ingredients allows for a synergistic effect. Salicylic acid enhances the absorption of clobetasol propionate by removing the outer layer of the skin, ensuring that the corticosteroid can reach the affected area more effectively. This enhanced penetration increases the efficacy of the treatment and reduces the amount of clobetasol propionate needed, minimizing the potential for side effects associated with potent corticosteroids. The overall effect is reduced inflammation and scaling, leading to improved skin appearance and reduced discomfort. COMBISALIC CREAM is designed for topical application, ensuring that the medication is delivered directly to the affected area, minimizing systemic absorption and side effects.
• In summary, Clobetasol propionate targets the inflammatory response, while salicylic acid exfoliates and enhances penetration. This dual-action approach makes COMBISALIC CREAM an effective treatment for skin conditions characterized by inflammation, scaling, and excessive skin cell proliferation. It's crucial to use this medication exactly as prescribed by a healthcare professional to maximize its benefits and minimize potential side effects.

- Skin irritation, redness, or burning - Itching - Dryness or peeling of the skin - Allergic reactions (rash, hives, swelling) - Thinning of the skin - Changes in skin color - Acne or folliculitis - Secondary skin infections - Contact dermatitis

• Apply the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and apply your next dose as directed. Do not apply a double dose to make up for the missed one.

• Keep COMBISALIC CREAM 20GM away from the reach of children and pets.
• Store COMBISALIC CREAM 20GM at room temperature.

• Apply a thin layer of COMBISALIC CREAM 20 GM to the affected area as directed by your doctor. Avoid applying it to unaffected skin.
• Wash your hands thoroughly before and after applying COMBISALIC CREAM 20 GM, unless your hands are the area being treated.
• Do not cover the treated area with bandages or dressings unless instructed by your doctor. Covering the area can increase absorption and the risk of side effects.
• Avoid using COMBISALIC CREAM 20 GM on your face, groin, or underarms unless specifically directed by your doctor. These areas are more sensitive and prone to irritation.
• If you experience any burning, stinging, swelling, or other irritation at the application site, discontinue use and consult your doctor immediately.
• Use COMBISALIC CREAM 20 GM regularly and for the full course of treatment as prescribed by your doctor, even if your symptoms improve. Stopping too early may lead to a recurrence of the infection or condition.
• Inform your doctor about all other medications, including topical products, you are using before starting COMBISALIC CREAM 20 GM to avoid potential drug interactions.
• Keep COMBISALIC CREAM 20 GM away from your eyes, nose, and mouth. If accidental contact occurs, rinse thoroughly with water.
• Store COMBISALIC CREAM 20 GM at room temperature, away from heat and direct sunlight. Keep it out of reach of children.
• Consult your doctor if your condition does not improve after several weeks of using COMBISALIC CREAM 20 GM, or if it worsens.

• COMBISALIC CREAM 20 GM is for external use. Since this medicine is to be applied topically, food interaction is unlikely.