CREVAST F 10MG TABLET 10'S
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CREVAST F 10MG TABLET 10'S
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CREVAST F 10MG TABLET 10'S

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CREVAST F 10MG TABLET 10'S

By ERIS LIFESCIENCES LIMITED

MRP

294.18

₹250.05

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About CREVAST F 10MG TABLET 10'S

  • CREVAST F 10MG TABLET is a combination medicine used to lower elevated cholesterol and triglyceride levels in the blood when lifestyle changes (like a low-fat diet) haven't been successful. It contains two active ingredients: Rosuvastatin and Fenofibrate.
  • Rosuvastatin belongs to a class of drugs called statins. It works by blocking an enzyme in the liver that is needed to produce cholesterol. This helps to lower LDL cholesterol (bad cholesterol) and triglycerides while increasing HDL cholesterol (good cholesterol).
  • Fenofibrate belongs to a class of drugs called fibrates. It works primarily by decreasing the production of triglycerides and increasing the breakdown of triglycerides, thereby lowering their levels in the blood. It also helps to increase HDL cholesterol.
  • CREVAST F 10MG TABLET is typically prescribed to individuals at high risk of cardiovascular disease, such as heart attack or stroke. It is important to use this medicine in conjunction with a healthy diet and regular exercise to achieve the best results.
  • Always take CREVAST F 10MG TABLET exactly as prescribed by your doctor. The usual dose is one tablet daily, taken orally with or without food. Do not crush, chew, or break the tablet. Swallow it whole with a glass of water. Your doctor may adjust your dose depending on your response to the medicine and your cholesterol levels.
  • Before taking CREVAST F 10MG TABLET, tell your doctor if you have any liver or kidney problems, gallbladder disease, or a history of muscle problems. Also, inform your doctor about all other medicines you are taking, including over-the-counter drugs, herbal supplements, and vitamins.
  • Common side effects of CREVAST F 10MG TABLET may include muscle pain, headache, nausea, and abdominal pain. If you experience any severe side effects, such as muscle weakness, dark urine, or yellowing of the skin or eyes, stop taking the medicine and contact your doctor immediately.

Uses of CREVAST F 10MG TABLET 10'S

  • Treatment of High Cholesterol
  • Reducing the risk of cardiovascular diseases
  • Treatment of Mixed Dyslipidemia
  • Treatment of High Triglyceride Levels
  • Slowing the progression of atherosclerosis
  • Stroke Prevention
  • Myocardial Infarction (Heart Attack) Prevention

How CREVAST F 10MG TABLET 10'S Works

  • CREVAST F 10MG TABLET 10'S is a combination medication designed to manage high cholesterol and triglyceride levels in the blood. It contains two active ingredients: Atorvastatin and Fenofibrate, each working through different mechanisms to achieve optimal lipid control.
  • Atorvastatin belongs to a class of drugs called statins or HMG-CoA reductase inhibitors. It primarily works by blocking the action of an enzyme called HMG-CoA reductase, which is crucial for the synthesis of cholesterol in the liver. By inhibiting this enzyme, Atorvastatin reduces the production of LDL-cholesterol (low-density lipoprotein), often referred to as "bad" cholesterol. Lowering LDL-cholesterol helps prevent the buildup of plaque in the arteries, reducing the risk of heart attacks and strokes. Additionally, Atorvastatin can also slightly increase HDL-cholesterol (high-density lipoprotein), known as "good" cholesterol, further contributing to improved cardiovascular health.
  • Fenofibrate, on the other hand, belongs to a class of drugs called fibrates. It primarily works by activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). PPARα is a key regulator of lipid metabolism, particularly in the liver and adipose tissue. When Fenofibrate activates PPARα, it leads to increased breakdown and elimination of triglycerides, another type of fat in the blood. This activation also increases the production of HDL-cholesterol. By reducing triglycerides and increasing HDL-cholesterol, Fenofibrate complements the action of Atorvastatin, providing a more comprehensive approach to managing dyslipidemia (abnormal lipid levels).
  • The synergistic action of Atorvastatin and Fenofibrate in CREVAST F 10MG TABLET 10'S provides a dual approach to lipid management. Atorvastatin focuses on lowering LDL-cholesterol, while Fenofibrate targets triglycerides and boosts HDL-cholesterol. This combination is particularly beneficial for individuals who have mixed hyperlipidemia, characterized by elevated levels of both cholesterol and triglycerides. By addressing both aspects of dyslipidemia, CREVAST F 10MG TABLET 10'S effectively reduces the risk of cardiovascular events, such as heart attacks and strokes. It’s important to note that CREVAST F 10MG TABLET 10'S is most effective when used in conjunction with a healthy lifestyle, including a balanced diet, regular exercise, and weight management.
  • In summary, CREVAST F 10MG TABLET 10'S works by combining the cholesterol-lowering effects of Atorvastatin with the triglyceride-lowering and HDL-cholesterol-boosting effects of Fenofibrate. This dual mechanism helps to comprehensively manage dyslipidemia and reduce the risk of cardiovascular disease.

Side Effects of CREVAST F 10MG TABLET 10'SArrow

Common side effects of CREVAST F 10MG TABLET may include: Headache, Muscle pain, Weakness, Nausea, Abdominal pain, Constipation, Diarrhea, Flatulence, Increased liver enzymes. Uncommon side effects may include: Dizziness, Vomiting, Fatigue, Sleep disturbances (insomnia or nightmares), Memory loss, Tingling or numbness, Joint pain, Erectile dysfunction, Skin rash, Itching, Hair loss. Rare side effects may include: Severe muscle damage (rhabdomyolysis), Liver problems (hepatitis, jaundice), Allergic reactions (swelling of face, tongue, or throat, difficulty breathing), Pancreatitis, Peripheral neuropathy. Very rare side effects may include: Depression, Gynecomastia.

Safety Advice for CREVAST F 10MG TABLET 10'SArrow

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Allergies

Consult a Doctor

Consult your doctor if you have any known allergies to CREVAST F 10MG TABLET 10'S.

Dosage of CREVAST F 10MG TABLET 10'SArrow

  • The recommended dosage of CREVAST F 10MG TABLET 10'S varies depending on individual patient factors, including the severity of your condition, your response to treatment, and other medications you may be taking. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing.
  • Typically, the starting dose is one tablet daily, taken orally. Your doctor may adjust the dosage based on your lipid levels and overall health. The maximum daily dose should not exceed what your doctor prescribes. Consistency is key; try to take the tablet at the same time each day to maintain stable blood levels of the medication.
  • CREVAST F 10MG TABLET 10'S can be taken with or without food. However, following a consistent pattern each day can help improve adherence to the medication schedule. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
  • Regular monitoring of your lipid profile and liver function is essential while taking CREVAST F 10MG TABLET 10'S. Your doctor will schedule periodic blood tests to assess your response to the medication and make any necessary adjustments to your treatment plan. If you experience any unusual side effects, such as muscle pain, weakness, or dark urine, contact your doctor immediately. Inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential drug interactions. Take 'CREVAST F 10MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of CREVAST F 10MG TABLET 10'S?Arrow

  • If you miss a dose of CREVAST F 10MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store CREVAST F 10MG TABLET 10'S?Arrow

  • Keep CREVAST F 10MG TAB 1X10 away from the reach of children and pets.
  • Store CREVAST F 10MG TAB 1X10 at room temperature.

Benefits of CREVAST F 10MG TABLET 10'SArrow

  • CREVAST F 10MG TABLET 10'S is a combination medication primarily used to manage and improve cholesterol and triglyceride levels in the blood. It combines two active ingredients, Rosuvastatin and Fenofibrate, each addressing different aspects of lipid metabolism, leading to a comprehensive approach to cardiovascular health.
  • Rosuvastatin, a statin, works by inhibiting an enzyme called HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver. By blocking this enzyme, rosuvastatin reduces the amount of cholesterol the liver produces, particularly LDL cholesterol (often referred to as 'bad' cholesterol). Lowering LDL cholesterol levels is vital because high levels can lead to the buildup of plaque in the arteries, a condition known as atherosclerosis. This plaque buildup narrows the arteries, restricting blood flow and increasing the risk of heart attack and stroke. Rosuvastatin effectively lowers LDL cholesterol, reducing this risk and promoting healthier arteries.
  • Fenofibrate, on the other hand, is a fibrate that primarily works by increasing the breakdown of triglycerides and increasing HDL cholesterol (often referred to as 'good' cholesterol'). Triglycerides are another type of fat in the blood that, when elevated, can also contribute to cardiovascular disease. Fenofibrate activates a protein called PPARα (peroxisome proliferator-activated receptor alpha), which increases the production of enzymes that break down triglycerides and VLDL (very-low-density lipoprotein), another form of bad cholesterol. Simultaneously, it helps raise HDL cholesterol levels, which is beneficial because HDL cholesterol helps remove LDL cholesterol from the arteries, offering additional protection against heart disease.
  • The combined action of rosuvastatin and fenofibrate in CREVAST F 10MG TABLET 10'S provides a synergistic effect, addressing multiple lipid parameters simultaneously. This is particularly beneficial for individuals with mixed dyslipidemia, a condition characterized by high LDL cholesterol, high triglycerides, and low HDL cholesterol. By targeting all these factors, CREVAST F 10MG TABLET 10'S provides a more comprehensive approach to managing lipid levels and reducing cardiovascular risk.
  • Beyond its direct effects on cholesterol and triglyceride levels, CREVAST F 10MG TABLET 10'S also offers several other benefits. By improving the overall lipid profile, it helps reduce the risk of atherosclerosis, heart attack, stroke, and other cardiovascular complications. It can also improve the function of the endothelium, the inner lining of blood vessels, which plays a crucial role in maintaining vascular health. A healthy endothelium helps regulate blood flow, prevent blood clot formation, and reduce inflammation. Furthermore, some studies suggest that fenofibrate may have beneficial effects on blood sugar control, making CREVAST F 10MG TABLET 10'S potentially useful for individuals with diabetes or insulin resistance.
  • In summary, CREVAST F 10MG TABLET 10'S is a valuable medication for managing dyslipidemia and reducing cardiovascular risk. Its dual mechanism of action, combining a statin and a fibrate, allows it to effectively lower LDL cholesterol and triglycerides while raising HDL cholesterol. This comprehensive approach provides significant benefits for individuals with mixed dyslipidemia and those at high risk of cardiovascular events. Regular use, as prescribed by a healthcare professional, can contribute to a healthier heart and improved overall well-being. Always consult with your doctor to determine if CREVAST F 10MG TABLET 10'S is right for you and to discuss any potential risks or side effects.

How to use CREVAST F 10MG TABLET 10'SArrow

  • CREVAST F 10MG TABLET 10'S should be taken orally as directed by your physician. It is typically prescribed to be taken once daily, preferably in the evening, but your doctor will determine the best timing based on your specific needs and condition. Adhering to a consistent schedule will help you remember to take it regularly and maximize its effectiveness.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this could affect how the medication is released and absorbed by your body. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist; they may be able to offer alternative formulations or helpful tips.
  • CREVAST F 10MG TABLET 10'S can be taken with or without food. However, maintaining a consistent pattern relative to meals (e.g., always with food or always on an empty stomach) can help optimize absorption. Follow your doctor’s instructions regarding food intake in relation to taking this medication.
  • Continue taking CREVAST F 10MG TABLET 10'S for as long as your doctor prescribes it, even if you feel well. This medication helps manage your cholesterol and triglyceride levels, and discontinuing it without medical advice could lead to a return of elevated levels and increased risk of cardiovascular events. Regular monitoring of your lipid profile is essential while taking this medication. Your doctor will schedule follow-up appointments to assess your progress and make any necessary adjustments to your treatment plan.
  • If you miss a dose of CREVAST F 10MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. Doubling the dose can increase the risk of side effects. If you are unsure about what to do after missing a dose, consult your doctor or pharmacist for guidance.

Quick Tips for CREVAST F 10MG TABLET 10'SArrow

  • Take CREVAST F 10MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking it without consulting your physician, as this could affect your treatment.
  • CREVAST F 10MG TABLET 10'S is usually taken once daily, preferably in the evening. Consistency in timing helps maintain stable blood levels of the medication for optimal effectiveness.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting CREVAST F 10MG TABLET 10'S. This is crucial to avoid potential drug interactions that could impact its efficacy or increase the risk of side effects.
  • While taking CREVAST F 10MG TABLET 10'S, adopt a heart-healthy lifestyle. This includes following a balanced diet low in saturated fats and cholesterol, engaging in regular physical activity, and avoiding smoking. These lifestyle changes can significantly enhance the benefits of the medication.
  • Regular monitoring of liver function and lipid levels is recommended while you are on CREVAST F 10MG TABLET 10'S. Your doctor will schedule blood tests to assess how well the medication is working and to detect any potential adverse effects early on.
  • If you experience any unusual muscle pain, tenderness, or weakness while taking CREVAST F 10MG TABLET 10'S, notify your doctor immediately. These could be signs of a rare but serious side effect called myopathy, which requires prompt medical attention.

Food Interactions with CREVAST F 10MG TABLET 10'SArrow

  • CREVAST F 10MG TABLET 10'S can be taken with or without food. However, it is important to maintain a consistent dietary pattern while taking this medication. Avoid consuming large amounts of grapefruit or grapefruit juice, as it can increase the levels of the drug in your body and potentially increase the risk of side effects. Consult your doctor or pharmacist for further guidance on specific dietary recommendations.

FAQs

What is CREVAST F 10MG TABLET used for?Arrow

CREVAST F 10MG TABLET is primarily used to lower high levels of lipids such as cholesterol and triglycerides. It is also used to reduce the risk of heart disease and stroke.

How does CREVAST F 10MG TABLET work?Arrow

CREVAST F 10MG TABLET is a combination of two medicines: Atorvastatin and Fenofibrate. Atorvastatin is a statin that reduces the production of cholesterol, while Fenofibrate lowers triglycerides and increases good cholesterol (HDL).

What are the common side effects of CREVAST F 10MG TABLET?Arrow

Common side effects of CREVAST F 10MG TABLET include nausea, stomach pain, constipation, muscle pain, and headache.

Can I drink alcohol while taking CREVAST F 10MG TABLET?Arrow

Drinking alcohol while taking CREVAST F 10MG TABLET may increase the risk of liver problems. Therefore, it is advisable to avoid alcohol consumption with this medication.

Is CREVAST F 10MG TABLET safe for pregnant women?Arrow

No, CREVAST F 10MG TABLET is not recommended during pregnancy as it may harm the unborn baby.

What happens if I miss a dose of CREVAST F 10MG TABLET?Arrow

If you miss a dose of CREVAST F 10MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

How to store CREVAST F 10MG TABLET?Arrow

Store CREVAST F 10MG TABLET at room temperature, away from direct sunlight and moisture. Keep out of reach of children and pets.

Can CREVAST F 10MG TABLET cause muscle pain?Arrow

Yes, CREVAST F 10MG TABLET can cause muscle pain and weakness. Contact your doctor if you experience severe muscle pain.

Does CREVAST F 10MG TABLET affect the kidneys?Arrow

CREVAST F 10MG TABLET should be used with caution in people with kidney problems. Inform your doctor if you have kidney disease.

What medications should be avoided with CREVAST F 10MG TABLET?Arrow

Certain medications, such as some antifungals (e.g., ketoconazole), macrolide antibiotics (e.g., erythromycin), and other cholesterol-lowering drugs (e.g., gemfibrozil) can interact with CREVAST F 10MG TABLET. Inform your doctor before starting any new medication.

Can CREVAST F 10MG TABLET be taken with or without food?Arrow

CREVAST F 10MG TABLET can be taken with or without food, as directed by your doctor.

What are the symptoms of an overdose of CREVAST F 10MG TABLET?Arrow

Symptoms of an overdose of CREVAST F 10MG TABLET may include nausea, vomiting, muscle pain, and weakness. Seek immediate medical attention if you suspect an overdose.

Can I drink grapefruit juice while taking CREVAST F 10MG TABLET?Arrow

Grapefruit juice can increase the levels of CREVAST F 10MG TABLET, potentially increasing the risk of side effects. It is advisable to avoid grapefruit juice consumption with this medication.

What should I do if I experience an allergic reaction after taking CREVAST F 10MG TABLET?Arrow

If you experience an allergic reaction after taking CREVAST F 10MG TABLET, such as skin rash, itching, swelling, or difficulty breathing, seek immediate medical attention.

Is CREVAST F 10MG TABLET available under other brand names?Arrow

The combination of Atorvastatin and Fenofibrate may be available under other brand names. Consult your pharmacist or doctor for more information.

References

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CRESTOR (rosuvastatin calcium) tablets prescribing information. This FDA document provides detailed pharmaceutical information about rosuvastatin, including its chemical structure, mechanism of action, pharmacokinetics, and clinical trial data.

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Rosuvastatin DrugBank entry. A comprehensive resource with information on rosuvastatin's chemical properties, pharmacology, interactions, and approved indications.

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Efficacy and Safety of Rosuvastatin in Asian Patients: A Meta-Analysis of Randomized Controlled Trials. This research article, published in PubMed Central, focuses on the efficacy and safety of rosuvastatin, the active ingredient in CREVAST F, specifically in Asian populations.

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Crestor (rosuvastatin) EPAR. This is the European Medicines Agency's public assessment report for Crestor, containing detailed information about the drug's evaluation and approval process in Europe.

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Rosuvastatin - ScienceDirect Topics. This ScienceDirect page provides a concise overview of rosuvastatin, including its mechanism of action, uses, and potential side effects, sourced from various scientific publications.

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ERIS LIFESCIENCES LIMITED

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CREVAST F 10MG TABLET 10'S

MRP

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₹250.05

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