DAPASACH S 10/50MG TABLET 10'S
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DAPASACH S 10/50MG TABLET 10'SDAPASACH S 10/50MG TABLET 10'SDAPASACH S 10/50MG TABLET 10'S
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DAPASACH S 10/50MG TABLET 10'S

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DAPASACH S 10/50MG TABLET 10'S

By CIPLA PHARMACEUTICAL COMPANY LIMITED

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About DAPASACH S 10/50MG TABLET 10'S

  • Dapasach S 10/50mg Tablet is a combination medicine used to lower blood sugar levels in adults with type 2 diabetes mellitus. It contains two active ingredients: dapagliflozin and sitagliptin. Dapagliflozin belongs to a class of drugs called SGLT2 inhibitors, while sitagliptin belongs to a class of drugs called DPP-4 inhibitors. This dual-action approach helps manage blood sugar levels more effectively than either medication alone.
  • Dapagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood. This allows excess glucose to be excreted through urine, thereby lowering blood sugar levels. Sitagliptin, on the other hand, works by increasing the levels of incretin hormones in the body. These hormones stimulate the release of insulin from the pancreas and reduce the production of glucagon, a hormone that raises blood sugar levels. By enhancing insulin secretion and suppressing glucagon release, sitagliptin helps regulate blood sugar levels after meals.
  • Dapasach S 10/50mg Tablet is typically prescribed in conjunction with diet and exercise to improve glycemic control in adults with type 2 diabetes. It is important to take this medication as directed by your healthcare provider. Common side effects may include urinary tract infections, yeast infections, and increased urination. It is crucial to stay hydrated while taking this medication. Regular monitoring of blood sugar levels is essential to assess the effectiveness of the treatment and make any necessary adjustments to the dosage. Individuals with kidney problems should use this medicine with caution and consult their doctor before use.
  • This medication offers a convenient way to manage blood sugar levels by combining two complementary mechanisms of action into a single tablet. Always consult with your doctor or pharmacist for personalized advice and to address any specific concerns or questions regarding Dapasach S 10/50mg Tablet.

Uses of DAPASACH S 10/50MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Reducing the risk of heart disease (in patients with type 2 diabetes)
  • Slowing the progression of kidney disease (in patients with type 2 diabetes)
  • Aiding in weight management (in some patients)

How DAPASACH S 10/50MG TABLET 10'S Works

  • DAPASACH S 10/50MG TABLET 10'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Dapagliflozin and Sitagliptin, each working through distinct mechanisms to improve glycemic control.
  • Dapagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. The kidneys filter glucose from the blood, and SGLT2 proteins are responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin inhibits SGLT2 in the kidneys, reducing the reabsorption of glucose. This allows excess glucose to be eliminated from the body through urine, thereby lowering blood sugar levels. This process is also associated with mild weight loss and blood pressure reduction, providing additional benefits for many patients with type 2 diabetes. By promoting glucose excretion, Dapagliflozin helps improve insulin sensitivity over time and reduces the burden on the pancreas.
  • Sitagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released in response to food intake and stimulate insulin release from the pancreas while also suppressing glucagon secretion. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This leads to enhanced insulin secretion when blood sugar levels are high and reduced glucagon secretion, which prevents the liver from releasing excess glucose into the bloodstream. The overall effect is better post-meal blood sugar control and improved glycemic regulation throughout the day. Sitagliptin works in a glucose-dependent manner, meaning its effects are more pronounced when blood sugar levels are elevated, reducing the risk of hypoglycemia.
  • In summary, DAPASACH S 10/50MG TABLET 10'S works through a dual mechanism of action. Dapagliflozin reduces glucose reabsorption in the kidneys, leading to glucose excretion, while Sitagliptin enhances the effects of incretin hormones, promoting insulin secretion and reducing glucagon secretion. This synergistic action provides comprehensive blood sugar control, addressing multiple aspects of type 2 diabetes. This combination helps patients achieve better HbA1c levels, reduce the risk of diabetes-related complications, and improve overall metabolic health. Regular monitoring and lifestyle modifications, including diet and exercise, are essential to maximize the benefits of this medication.

Side Effects of DAPASACH S 10/50MG TABLET 10'SArrow

Possible side effects of DAPASACH S 10/50MG TABLET 10'S may include: * **Common Side Effects:** * Hypoglycemia (low blood sugar) * Nausea * Vomiting * Diarrhea * Abdominal pain * Headache * Dizziness * Urinary tract infections (UTIs) * Genital infections (yeast infections) * Increased urination * Thirst * **Uncommon Side Effects:** * Dehydration * Constipation * Skin rash or itching * Changes in cholesterol levels * Kidney problems * Pancreatitis (inflammation of the pancreas) * Ketoacidosis (increased ketones in your blood or urine) * **Rare Side Effects:** * Severe allergic reactions (anaphylaxis) * Liver problems * Fournier's gangrene (a serious infection of the genitals or perineum) **Note:** This is not an exhaustive list. If you experience any unusual or severe side effects, consult your doctor immediately.

Safety Advice for DAPASACH S 10/50MG TABLET 10'SArrow

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Allergies

Allergies

Allergies: Caution is advised while taking DAPASACH S 10/50MG TABLET 10'S.

Dosage of DAPASACH S 10/50MG TABLET 10'SArrow

  • The recommended dosage of DAPASACH S 10/50MG TABLET 10'S is individualized and depends on several factors, including the patient's condition, the severity of the disease, other medications being taken, and the patient's response to treatment. Typically, the starting dose is one tablet daily, but your physician will determine the most appropriate dose for you. The tablet should be swallowed whole with a glass of water, preferably at the same time each day to maintain consistent drug levels in your body. It can be taken with or without food, but consistency in how you take it can help minimize potential side effects.
  • Your doctor may adjust your dosage over time to achieve the best possible control of your blood sugar levels or to manage your specific health condition effectively. It is crucial to follow your doctor's instructions precisely and to attend all scheduled follow-up appointments. Do not change your dose or stop taking DAPASACH S 10/50MG TABLET 10'S without consulting your healthcare provider, as this could lead to undesirable effects or a worsening of your condition.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have any questions or concerns about your dosage, or if you experience any unusual side effects, contact your doctor or pharmacist immediately.
  • Take 'DAPASACH S 10/50MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of DAPASACH S 10/50MG TABLET 10'S?Arrow

  • If you miss a dose of DAPASACH S 10/50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store DAPASACH S 10/50MG TABLET 10'S?Arrow

  • Keep DAPASACH S 10/50MG TAB 1X10 away from the reach of children and pets.
  • Store DAPASACH S 10/50MG TAB 1X10 at room temperature.

Benefits of DAPASACH S 10/50MG TABLET 10'SArrow

  • DAPASACH S 10/50MG TABLET 10'S offers a dual-action approach to managing type 2 diabetes by combining dapagliflozin and sitagliptin. Dapagliflozin belongs to a class of medications known as sodium-glucose cotransporter 2 (SGLT2) inhibitors, while sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. This combination provides synergistic benefits in controlling blood sugar levels.
  • One of the primary benefits of DAPASACH S is its ability to lower blood sugar levels effectively. Dapagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood, leading to excess glucose being excreted through urine. This mechanism helps reduce blood sugar levels, particularly after meals. Sitagliptin enhances the levels of incretin hormones in the body, which stimulate insulin release and decrease glucagon secretion, both contributing to better glucose control.
  • Beyond blood sugar control, DAPASACH S offers several additional advantages. Dapagliflozin has been shown to promote weight loss in some individuals, which can be a significant benefit for those with type 2 diabetes who are also struggling with obesity. This weight loss effect is attributed to the excretion of glucose through urine, resulting in a loss of calories. Sitagliptin generally has a weight-neutral effect, meaning it doesn't typically cause weight gain or loss.
  • Furthermore, DAPASACH S may have a positive impact on cardiovascular health. Studies have indicated that dapagliflozin can reduce the risk of heart failure and cardiovascular death in patients with type 2 diabetes and established cardiovascular disease. This cardioprotective effect makes DAPASACH S a valuable option for individuals with both diabetes and heart issues. While sitagliptin's cardiovascular benefits are still being investigated, current evidence suggests it is generally safe for the heart.
  • Another notable benefit is the convenience of a single tablet combining two medications. This can improve adherence to treatment, as patients only need to take one pill instead of multiple ones. Improved adherence can lead to better blood sugar control and overall health outcomes. DAPASACH S is typically taken once daily, making it easy to incorporate into a daily routine. This simplified regimen can be particularly helpful for individuals who have difficulty managing complex medication schedules.
  • DAPASACH S can also help reduce the risk of certain diabetes-related complications. By effectively controlling blood sugar levels, it can minimize the likelihood of developing long-term complications such as kidney disease, nerve damage (neuropathy), and eye damage (retinopathy). These complications can significantly impact quality of life, so proactive management of blood sugar is essential.
  • Finally, DAPASACH S can lead to improvements in overall well-being. By effectively managing blood sugar levels, patients may experience increased energy levels, reduced fatigue, and improved mood. Better control of diabetes can also lead to a greater sense of control over one's health, which can have a positive impact on mental and emotional well-being.

How to use DAPASACH S 10/50MG TABLET 10'SArrow

  • DAPASACH S 10/50MG TABLET 10'S is an oral medication used to manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients, Dapagliflozin and Sitagliptin, which work through different mechanisms to improve glycemic control. Always adhere to your doctor's instructions regarding dosage and timing. Typically, it is taken once daily, preferably in the morning, with or without food. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • Consistency is key to the effectiveness of this medication. Try to take it at the same time each day to maintain a steady level of the drugs in your system. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking DAPASACH S 10/50MG TABLET 10'S, it's crucial to monitor your blood sugar levels regularly, as directed by your healthcare provider. This helps you understand how the medication is working and allows for adjustments to your treatment plan if necessary. Be aware of the symptoms of both high and low blood sugar and know how to manage them. This medicine works best when combined with a healthy diet and regular exercise. Follow the dietary recommendations provided by your doctor or a registered dietitian, and engage in physical activity as advised.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with DAPASACH S 10/50MG TABLET 10'S. Pay attention to any side effects you experience, and report them to your doctor promptly. Common side effects may include urinary tract infections, yeast infections, and changes in urination. Stay hydrated by drinking plenty of water throughout the day, unless otherwise directed by your doctor. Regular check-ups with your doctor are essential to monitor your overall health and the effectiveness of your diabetes management plan.

Quick Tips for DAPASACH S 10/50MG TABLET 10'SArrow

  • **Take DAPASACH S 10/50MG TABLET 10'S as prescribed by your doctor:** Always follow your doctor's instructions regarding dosage and timing. Do not self-medicate or change the dosage without consulting your doctor. It is crucial to adhere to the prescribed treatment plan for optimal results.
  • **Take it at the same time each day:** For consistent blood sugar control, take DAPASACH S 10/50MG TABLET 10'S at the same time every day. This helps maintain a steady level of medication in your body, leading to better management of your diabetes. Consider setting a daily reminder to help you remember.
  • **Monitor your blood sugar levels regularly:** While taking DAPASACH S 10/50MG TABLET 10'S, it's important to monitor your blood sugar levels regularly as directed by your healthcare provider. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Keep a log of your blood sugar readings to share with your doctor.
  • **Be aware of potential side effects:** DAPASACH S 10/50MG TABLET 10'S may cause side effects such as nausea, diarrhea, or hypoglycemia (low blood sugar). Be aware of these potential side effects and contact your doctor if they become severe or persistent. Learn to recognize the symptoms of low blood sugar (e.g., shakiness, sweating, confusion) and know how to treat it quickly (e.g., with glucose tablets or juice).
  • **Maintain a healthy lifestyle:** DAPASACH S 10/50MG TABLET 10'S works best when combined with a healthy lifestyle. This includes eating a balanced diet, exercising regularly, and maintaining a healthy weight. Consult with a registered dietitian or certified diabetes educator for personalized guidance on diet and exercise plans tailored to your needs.
  • **Stay hydrated:** Drink plenty of water throughout the day. Staying hydrated helps your body function properly and can also aid in managing blood sugar levels. Dehydration can sometimes mimic symptoms of low blood sugar, so it's important to maintain adequate fluid intake.
  • **Inform your doctor about other medications:** Before starting DAPASACH S 10/50MG TABLET 10'S, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medications can interact with DAPASACH S 10/50MG TABLET 10'S and affect its effectiveness or increase the risk of side effects.
  • **Store properly:** Store DAPASACH S 10/50MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date before use and discard any expired medication properly. Do not store in the bathroom.
  • **Follow Dietary Guidelines:** Adhere to the dietary recommendations provided by your healthcare provider or a registered dietitian. Focus on consuming whole grains, lean proteins, fruits, and vegetables. Limit your intake of sugary drinks, processed foods, and saturated fats. Consistent dietary habits can significantly impact your blood sugar control.
  • **Regular Exercise:** Engage in regular physical activity, such as brisk walking, jogging, swimming, or cycling, for at least 30 minutes most days of the week. Exercise helps improve insulin sensitivity, lower blood sugar levels, and promote overall cardiovascular health. Consult your doctor before starting any new exercise program, especially if you have other health conditions.

Food Interactions with DAPASACH S 10/50MG TABLET 10'SArrow

  • DAPASACH S 10/50MG TABLET 10'S may be taken with or without food. However, it is important to take it at the same time each day to maintain consistent blood sugar levels. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of side effects such as hypoglycemia.

FAQs

What is Dapasach S 10/50mg Tablet 10's?Arrow

Dapasach S 10/50mg Tablet 10's is a combination medicine used to treat type 2 diabetes mellitus. It contains dapagliflozin and sitagliptin.

How to use Dapasach S 10/50mg Tablet 10's?Arrow

Take Dapasach S 10/50mg Tablet 10's in the dose and duration as advised by your doctor. It can be taken with or without food, but it is better to take it at the same time every day for better results.

What are the common side effects of Dapasach S 10/50mg Tablet 10's?Arrow

Common side effects of Dapasach S 10/50mg Tablet 10's include nausea, vomiting, diarrhea, abdominal pain, and headache.

Is Dapasach S 10/50mg Tablet 10's harmful to the kidneys?Arrow

Dapasach S 10/50mg Tablet 10's should be used with caution in people with kidney problems. Talk to your doctor if you have kidney disease.

Does Dapasach S 10/50mg Tablet 10's cause weight loss?Arrow

Dapasach S 10/50mg Tablet 10's may cause weight loss, but this does not happen to everyone.

Can I drink alcohol with Dapasach S 10/50mg Tablet 10's?Arrow

Avoid drinking alcohol with Dapasach S 10/50mg Tablet 10's, as it can increase the risk of low blood sugar.

Is Dapasach S 10/50mg Tablet 10's safe for pregnant women?Arrow

There is not enough information about the safety of Dapasach S 10/50mg Tablet 10's during pregnancy. Therefore, it should only be used if clearly needed by the doctor.

Is Dapasach S 10/50mg Tablet 10's safe for breastfeeding women?Arrow

It is not known whether Dapasach S 10/50mg Tablet 10's is excreted in breast milk. Therefore, breastfeeding women should exercise caution while using it.

How to store Dapasach S 10/50mg Tablet 10's?Arrow

Store Dapasach S 10/50mg Tablet 10's at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

What happens if I miss a dose of Dapasach S 10/50mg Tablet 10's?Arrow

If you miss a dose of Dapasach S 10/50mg Tablet 10's, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can Dapasach S 10/50mg Tablet 10's be taken with other medications?Arrow

Dapasach S 10/50mg Tablet 10's can interact with other medications. Therefore, tell your doctor about all your medications before starting any new medicine.

Is Dapasach S 10/50mg Tablet 10's used for type 1 diabetes?Arrow

No, Dapasach S 10/50mg Tablet 10's is only used to treat type 2 diabetes.

What are the other medications containing Dapagliflozin and Sitagliptin?Arrow

Other medications containing Dapagliflozin and Sitagliptin are available under various brand names. Consult your doctor or pharmacist for more details.

What are the symptoms of an overdose of Dapasach S 10/50mg Tablet 10's?Arrow

Symptoms of an overdose of Dapasach S 10/50mg Tablet 10's may include nausea, vomiting, abdominal pain, dizziness, and fainting. Contact a doctor immediately if you think you have taken too much of the medicine.

What foods should I avoid while taking Dapasach S 10/50mg Tablet 10's?Arrow

It is advisable to avoid high sugar and high-fat foods while taking Dapasach S 10/50mg Tablet 10's. Maintain a balanced diet and follow the dietary instructions given by your doctor.

References

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FDA Label for Dapagliflozin/Saxagliptin combination product (Qtern): This provides detailed information on the clinical pharmacology, pharmacokinetics, and clinical trial data for the combination of dapagliflozin and saxagliptin. It includes sections on drug interactions and adverse reactions.

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DrugBank entry for Dapagliflozin: A comprehensive database entry with information on the mechanism of action, pharmacokinetics, metabolism, and drug interactions of dapagliflozin. Includes links to relevant scientific literature.

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DrugBank entry for Saxagliptin: Similar to the Dapagliflozin entry, this provides detailed information on the mechanism of action, pharmacokinetics, metabolism, and drug interactions of saxagliptin. Also includes links to scientific literature.

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Saxagliptin: a review of its pharmacology and clinical use in type 2 diabetes mellitus.: Published review article on Saxagliptin pharmacology.

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Dapagliflozin: A review of its use in the treatment of type 2 diabetes mellitus.: Published review article on Dapagliflozin pharmacology.

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