DARZALEX 100MG/5ML INJECTION
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DARZALEX 100MG/5ML INJECTION
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DARZALEX 100MG/5ML INJECTION

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DARZALEX 100MG/5ML INJECTION

By JOHNSON & JOHNSON

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18900

₹16065

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Product DetailsArrow

About DARZALEX 100MG/5ML INJECTION

  • DARZALEX 100MG/5ML INJECTION is a targeted cancer therapy containing the active ingredient Daratumumab, a monoclonal antibody. Monoclonal antibodies are designed to recognize and attach to specific targets on cancer cells, ultimately leading to their destruction. This medication is specifically used to treat multiple myeloma, a type of bone marrow cancer, in adults aged 18 years and older. It's crucial to inform your doctor if you have a history of hepatitis B infection, as DARZALEX 100MG/5ML INJECTION may reactivate the virus. This medicine can also decrease platelet and white blood cell counts, potentially affecting blood clotting and increasing the risk of infections. Regular monitoring of blood counts is essential during treatment.
  • Avoid using DARZALEX 100MG/5ML INJECTION if you have a known allergy to Daratumumab or any other ingredients in the medication. This medicine is generally not recommended for use in children and adolescents due to a lack of sufficient safety and efficacy data. Immediately notify your doctor if you experience any infusion-related reactions, which may include swelling of the face, lips, mouth, tongue, or throat. These reactions can range in severity and may require medical intervention, such as administering additional medications or temporarily stopping or slowing down the infusion. Your healthcare team will closely monitor you during and after each infusion to manage any potential reactions.
  • Before starting DARZALEX 100MG/5ML INJECTION, inform your doctor if you are on a salt-controlled diet, as this medicine contains sodium, which may impact your dietary restrictions. Also, disclose any history of breathing problems such as asthma or chronic obstructive pulmonary disease (COPD), or if you have previously had shingles, as these conditions may influence your treatment plan. This medicine can interfere with blood tests used to determine your blood type, potentially leading to inaccurate results. Therefore, always inform healthcare providers that you are receiving DARZALEX 100MG/5ML INJECTION before any blood transfusions. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your doctor. Women of childbearing potential should use effective contraception during and for three months after completing treatment with DARZALEX 100MG/5ML INJECTION.

Uses of DARZALEX 100MG/5ML INJECTION

  • Treatment of Multiple Myeloma, which may involve various approaches like chemotherapy, stem cell transplant, targeted therapy using medications such as DARZALEX 100MG/5ML INJECTION, radiation therapy, and supportive care to manage symptoms and improve the patient's quality of life.

Side Effects of DARZALEX 100MG/5ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects include infusion reactions (itching, wheezing, chills, fever, throat tightness, runny nose, headache, low pressure), changes in blood tests, and a decrease in blood cell counts. Common side effects include nausea, vomiting, back pain, muscle spasms, diarrhea, tiredness, shortness of breath, upper respiratory tract infection, tingling, numbness, or pain, constipation, trouble sleeping, dizziness, and joint pain.

  • Infusion reactions (itching, wheezing, chills, fever, throat tightness, runny nose, headache, low pressure)
  • Changes in blood tests
  • Decrease in blood cell counts
  • Nausea, vomiting
  • Back pain, muscle spasms
  • Diarrhea
  • Tiredness
  • Shortness of breath
  • Upper respiratory tract infection
  • Tingling, numbness, or pain
  • Constipation
  • Trouble sleeping
  • Dizziness
  • Joint pain

Safety Advice for DARZALEX 100MG/5ML INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

Your doctor will prescribe DARZALEX 100MG/5ML INJECTION only if needed, as this medicine might cause harm to the unborn baby. So notify your doctor before starting the preganat if you are preganat or planning to get pregnant. Use effective contraception during and after the treatment for three months.

Dosage of DARZALEX 100MG/5ML INJECTIONArrow

  • DARZALEX 100MG/5ML INJECTION should only be administered by a trained doctor or nurse. It is crucial not to attempt self-administration. The dosage and duration of your treatment will be determined by your doctor, taking into account the severity of your condition, your overall health, and other relevant factors. This medication is administered as an intravenous infusion, which means it's delivered directly into your vein over a period of time.
  • During the infusion, you will be closely monitored by healthcare professionals to watch for any potential side effects or adverse reactions. This careful monitoring ensures that any issues are addressed promptly and effectively. Your doctor will provide you with specific instructions regarding the infusion process and what to expect.
  • It's important to follow your doctor's instructions precisely and to attend all scheduled appointments. If you have any concerns or questions about your treatment, don't hesitate to discuss them with your doctor or nurse. They are there to support you throughout your therapy and ensure you receive the best possible care.

How to store DARZALEX 100MG/5ML INJECTION?Arrow

  • Keep DARZALEX 100MG INJ 5ML away from the reach of children and pets.
  • Store DARZALEX 100MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of DARZALEX 100MG/5ML INJECTIONArrow

  • DARZALEX 100MG/5ML INJECTION is a targeted therapy that works by specifically attaching to the CD38 protein, which is highly expressed on multiple myeloma cells. This targeted approach helps minimize damage to healthy cells.
  • Once DARZALEX 100MG/5ML INJECTION binds to CD38, it triggers several mechanisms to eliminate the cancerous myeloma cells. It can directly induce apoptosis, or programmed cell death, in myeloma cells.
  • DARZALEX 100MG/5ML INJECTION also enhances the body's natural immune response to fight the cancer. It recruits immune cells like natural killer cells and cytotoxic T-cells to attack and destroy the myeloma cells. Furthermore, it can activate the complement system, a part of the immune system that directly lyses cancer cells.
  • By targeting CD38 and utilizing the body's own immune system, DARZALEX 100MG/5ML INJECTION offers a multifaceted approach to treating multiple myeloma, leading to improved outcomes for patients.

How to use DARZALEX 100MG/5ML INJECTIONArrow

  • DARZALEX 100MG/5ML INJECTION should only be administered by a qualified healthcare professional, such as a trained doctor or nurse. It is crucial to avoid self-administration of this medication. The specific dosage and the length of your treatment will be determined by your doctor, taking into account the severity of your condition, your overall health, and other relevant factors. This ensures that the treatment is tailored to your individual needs for the best possible outcome.
  • The medication will be administered as an intravenous infusion, which means it will be delivered directly into your bloodstream through a vein. During the infusion process, you will be closely monitored by healthcare staff for any potential side effects or adverse reactions. This allows for immediate intervention and management of any issues that may arise, ensuring your safety and comfort throughout the treatment.
  • It is important to inform your doctor about any existing medical conditions you have, as well as any other medications you are currently taking, including over-the-counter drugs and herbal supplements. This information will help your doctor make informed decisions about your treatment plan and minimize the risk of potential drug interactions or complications. Close communication with your healthcare provider is key to a successful treatment journey.

FAQs

Is DARZALEX 100MG/5ML INJECTION chemotherapy medicine?

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No, It is not a type of chemotherapy. DARZALEX 100MG/5ML INJECTION is a monoclonal antibody, a type of immunotherapy medication that works by stimulating the body's immune system to attack cancer cells.

How often should I need to receive DARZALEX 100MG/5ML INJECTION treatments?

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The frequency of DARZALEX 100MG/5ML INJECTION treatments can vary depending on the type and stage of the cancer being treated and other factors, such as the patient's overall health.

Does DARZALEX 100MG/5ML INJECTION cure cancer?

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DARZALEX 100MG/5ML INJECTION is not a cure for cancer. Instead, it can help to slow down or restrict the growth and spread of cancer cells, improving the quality of patients with certain types of cancer.

Do I need to maintain any diet during the treatment with DARZALEX 100MG/5ML INJECTION?

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No, you dont need to maintain any diet. Instead, inform your doctor if you are on a salt-controlled diet, as DARZALEX 100MG/5ML INJECTION contains sodium.

I had a history of hepatitis B virus. Should I inform it before taking the DARZALEX 100MG/5ML INJECTION?

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Yes, informing the past with HBV and every underlying medical condition before starting the treatment is mandatory.

Does DARZALEX 100MG/5ML INJECTION have any interactions with other drugs?

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There are no known drug interactions with DARZALEX 100MG/5ML INJECTION.

What advice should I follow while taking DARZALEX 100MG/5ML INJECTION?

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If you experience any symptoms mentioned above, consult your doctor immediately. While undergoing treatment, use effective contraception and continue it for three months after stopping treatment. DARZALEX 100MG/5ML INJECTION is not recommended for children and adolescents under 18 years. Do not freeze the medicine. Before starting the treatment, inform your doctor about every underlying medical condition. Talk to your physician if you are on a salt-controlled diet, as this medicine contains sodium.

What molecule/combination is used for making DARZALEX 100MG/5ML INJECTION?

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DARATUMUMAB is the molecule/combination used for making DARZALEX 100MG/5ML INJECTION.

For which ailments/diseases/conditions is DARZALEX 100MG/5ML INJECTION prescribed?

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DARZALEX 100MG/5ML INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Janssen-Cilag International NV, Electronic medicines compendium (EMC)

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Janssen Biotech, Inc, US Food and Drug Administration

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Danai Dima et al.; Evaluating Daratumumab in the Treatment of Multiple Myeloma: Safety, Efficacy, and Place in Therapy; Cancer Management and Research; Published on 26/08/2020

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Marketer / Manufacturer Details

JOHNSON & JOHNSON

Country of Origin -

India

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DARZALEX 100MG/5ML INJECTION

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₹16065

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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