DEFCORT TM TABLET 10'S
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DEFCORT TM TABLET 10'S
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DEFCORT TM TABLET 10'S

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DEFCORT TM TABLET 10'S

By MACLEODS PHARMACEUTICALS PRIVATE LIMITED

MRP

641.3

₹545.1

15 % OFF

₹54.51 Only /

Tablet

10

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Product DetailsArrow

About DEFCORT TM TABLET 10'S

  • DEFCORT™ Tablet 10's is a corticosteroid medication primarily used to reduce inflammation and suppress the immune system. It contains Deflazacort as its active ingredient, a potent anti-inflammatory and immunosuppressant agent. This medication is available in tablet form and is typically prescribed for various conditions where inflammation and immune system overactivity play a significant role.
  • Deflazacort, the active component of DEFCORT™ Tablet, is a prodrug that is rapidly converted to its active metabolite upon ingestion. It works by binding to glucocorticoid receptors in cells throughout the body. This binding triggers a cascade of intracellular events that lead to the suppression of inflammatory processes and the modulation of immune responses. Unlike some other corticosteroids, Deflazacort has been suggested to have a lower risk of certain side effects, such as bone density loss, though this can vary based on individual factors and dosage.
  • DEFCORT™ Tablet is commonly prescribed for conditions such as rheumatoid arthritis, asthma, allergies, and certain autoimmune diseases. It can also be used to manage inflammatory bowel diseases like Crohn's disease and ulcerative colitis. The dosage and duration of treatment with DEFCORT™ Tablet vary depending on the specific condition being treated, the severity of the condition, and the individual's response to the medication. It's crucial to take DEFCORT™ Tablet exactly as prescribed by your doctor and to complete the full course of treatment, even if you start to feel better.
  • Before starting DEFCORT™ Tablet, it is important to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking. Corticosteroids like Deflazacort can interact with other drugs and may not be suitable for everyone. Common side effects of DEFCORT™ Tablet may include weight gain, increased appetite, fluid retention, mood changes, and increased blood sugar levels. Long-term use of corticosteroids can also increase the risk of osteoporosis, cataracts, and glaucoma. Regular monitoring by your doctor is essential during treatment with DEFCORT™ Tablet to manage any potential side effects and ensure the medication is working effectively.
  • DEFCORT™ Tablet should be stored at room temperature, away from moisture and direct sunlight. Keep this medication out of the reach of children. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Always consult with your healthcare provider if you have any questions or concerns about your treatment with DEFCORT™ Tablet.

Uses of DEFCORT TM TABLET 10'S

  • Treatment of allergic conditions
  • Treatment of asthma
  • Treatment of arthritis
  • Treatment of skin disorders
  • Treatment of eye disorders
  • Treatment of rheumatic disorders
  • Treatment of psoriasis
  • Treatment of ulcerative colitis
  • Treatment of Crohn's disease
  • Treatment of some types of cancer
  • Treatment of autoimmune diseases
  • Treatment of inflammation
  • Treatment of allergic reactions
  • Treatment of breathing problems
  • Treatment of joint pain

How DEFCORT TM TABLET 10'S Works

  • DEFCORT TM TABLET 10'S contains deflazacort, a corticosteroid medication, that works by mimicking the effects of cortisol, a natural hormone produced by the adrenal glands. Corticosteroids like deflazacort have potent anti-inflammatory and immunosuppressive properties.
  • At the cellular level, deflazacort diffuses into cells and binds to specific intracellular corticosteroid receptors. This receptor-drug complex then translocates to the cell nucleus, where it interacts with DNA. This interaction modulates the transcription of various genes, either increasing or decreasing the production of specific proteins.
  • The anti-inflammatory effects of DEFCORT TM TABLET 10'S are achieved through several mechanisms. Firstly, it inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes. These substances are involved in the inflammatory cascade, contributing to pain, swelling, redness, and heat. By reducing their synthesis, deflazacort effectively reduces inflammation.
  • Secondly, deflazacort suppresses the migration of inflammatory cells, such as neutrophils and macrophages, to the site of inflammation. This reduces the cellular component of the inflammatory response, further alleviating symptoms.
  • Thirdly, DEFCORT TM TABLET 10'S affects the function of immune cells, such as T lymphocytes and B lymphocytes. It reduces the production of cytokines, which are signaling molecules that promote inflammation and immune responses. By suppressing cytokine production, deflazacort dampens the immune response.
  • The immunosuppressive effects of DEFCORT TM TABLET 10'S are also mediated through the modulation of immune cell function. It inhibits the proliferation and activation of T lymphocytes, which are crucial for cell-mediated immunity. This reduces the ability of the immune system to attack the body's own tissues, making it useful in treating autoimmune diseases.
  • Furthermore, deflazacort affects the function of antigen-presenting cells, such as dendritic cells, which are essential for initiating immune responses. It reduces their ability to present antigens to T lymphocytes, thereby suppressing the activation of the immune system.
  • In summary, DEFCORT TM TABLET 10'S exerts its therapeutic effects by modulating gene expression, inhibiting the production of inflammatory mediators, suppressing the migration of inflammatory cells, and modulating the function of immune cells. These actions collectively reduce inflammation and suppress the immune response, making it effective in treating a wide range of conditions.

Side Effects of DEFCORT TM TABLET 10'SArrow

Defcort (Deflazacort) can cause a range of side effects. Common side effects include: increased appetite, weight gain, indigestion, mood changes (such as irritability or depression), difficulty sleeping, increased sweating, acne, thinning skin, easy bruising, slow wound healing, increased risk of infection, muscle weakness, and fluid retention (swelling). Less common but more serious side effects include: high blood sugar, glaucoma, cataracts, osteoporosis (bone thinning), stomach ulcers, high blood pressure, and mental/mood changes (such as psychosis). Allergic reactions are rare, but seek immediate medical attention if you experience rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing. This is not an exhaustive list; other side effects may occur. Consult your doctor if you experience any troublesome symptoms while taking Defcort.

Safety Advice for DEFCORT TM TABLET 10'SArrow

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Allergies

Allergies

Unsafe if you are allergic to DEFCORT TM TABLET 10'S.

Dosage of DEFCORT TM TABLET 10'SArrow

  • The recommended dosage of DEFCORT TM TABLET 10'S varies significantly depending on the condition being treated, the severity of the condition, and the individual's response to the medication. It is crucial to adhere strictly to your physician's instructions regarding dosage and duration of treatment. DEFCORT TM TABLET 10'S is a corticosteroid and should not be taken without medical supervision.
  • For adults, the initial dosage may range from 5 mg to 60 mg per day, depending on the specific condition. In some cases, higher doses may be necessary for initial control of the disease. The dosage is typically adjusted gradually over time based on the patient's response. Your doctor will monitor your progress and adjust the dosage accordingly.
  • In children, the dosage is usually calculated based on body weight or body surface area. The prescribing doctor will determine the appropriate dose based on the child's specific needs and medical condition. It is vital to follow the doctor's instructions precisely when administering DEFCORT TM TABLET 10'S to children.
  • DEFCORT TM TABLET 10'S is usually taken orally with or without food. Taking it with food may help reduce stomach upset. The tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets unless specifically instructed by your doctor.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Sudden discontinuation of DEFCORT TM TABLET 10'S can lead to withdrawal symptoms, so it's important to consult your doctor before stopping the medication. Take 'DEFCORT TM TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of DEFCORT TM TABLET 10'S?Arrow

  • If you miss a dose of DEFCORT TM TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store DEFCORT TM TABLET 10'S?Arrow

  • Keep DEFCORT TM TAB 1X10 away from the reach of children and pets.
  • Store DEFCORT TM TAB 1X10 at room temperature.

Benefits of DEFCORT TM TABLET 10'SArrow

  • Defcort TM Tablet 10's is a corticosteroid medication primarily used to reduce inflammation and suppress the immune system. Its versatile applications span across various medical conditions, making it a valuable therapeutic agent.
  • One of the key benefits of Defcort TM Tablet 10's is its effectiveness in managing inflammatory conditions. It can provide relief from symptoms such as pain, swelling, redness, and heat associated with arthritis, bursitis, tendonitis, and other musculoskeletal disorders. By reducing inflammation, it helps improve joint mobility and overall comfort.
  • Defcort TM Tablet 10's is also widely used in the treatment of allergic reactions. It can alleviate symptoms like itching, sneezing, runny nose, and skin rashes caused by allergies to pollen, dust mites, pet dander, and certain foods or medications. It works by suppressing the immune system's response to allergens, thus reducing the severity of allergic reactions.
  • Furthermore, Defcort TM Tablet 10's plays a crucial role in managing autoimmune diseases. These are conditions where the immune system mistakenly attacks the body's own tissues and organs. Defcort TM Tablet 10's can help control the immune system's activity and reduce inflammation in autoimmune disorders such as lupus, rheumatoid arthritis, and inflammatory bowel disease. By suppressing the immune response, it helps prevent further damage to the body's tissues.
  • In addition to its anti-inflammatory and immunosuppressive properties, Defcort TM Tablet 10's can also be used to treat certain skin conditions. It can alleviate symptoms of eczema, psoriasis, and dermatitis, such as itching, redness, and scaling. It works by reducing inflammation and suppressing the immune system's activity in the skin, leading to clearer and healthier skin.
  • Defcort TM Tablet 10's is also sometimes prescribed to manage respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). It can help reduce inflammation in the airways, making it easier to breathe. It is typically used in combination with other medications, such as bronchodilators, to provide comprehensive relief from respiratory symptoms.
  • Moreover, Defcort TM Tablet 10's can be used as an adjunct treatment for certain types of cancer. It can help reduce inflammation and swelling associated with tumors and alleviate side effects of chemotherapy and radiation therapy. It works by suppressing the immune system and reducing the production of inflammatory substances.
  • It is important to note that Defcort TM Tablet 10's should only be used under the guidance of a healthcare professional. The dosage and duration of treatment will vary depending on the individual's condition and response to therapy. Long-term use of Defcort TM Tablet 10's can lead to side effects, such as weight gain, increased risk of infection, and bone loss. Therefore, it is crucial to discuss the risks and benefits of Defcort TM Tablet 10's with a doctor before starting treatment.

How to use DEFCORT TM TABLET 10'SArrow

  • Always take DEFCORT TM TABLET 10'S exactly as your doctor has told you. The dosage and duration of treatment depend on the severity of your condition and how you respond to the medication. Do not exceed the prescribed dose.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet unless specifically instructed by your doctor. DEFCORT TM TABLET 10'S can be taken with or without food, but it's best to take it at the same time each day to maintain consistent blood levels of the medicine. Consistency in timing helps to maximize the drug's effectiveness.
  • If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • During long-term treatment with DEFCORT TM TABLET 10'S, your doctor may advise you to follow a low-salt and high-protein diet. This helps to minimize potential side effects such as fluid retention and muscle wasting. Regular monitoring of your blood pressure, blood sugar levels, and bone density may also be necessary, especially if you have pre-existing conditions like hypertension, diabetes, or osteoporosis.
  • Do not stop taking DEFCORT TM TABLET 10'S abruptly, especially if you have been on it for a prolonged period. Sudden discontinuation can lead to withdrawal symptoms such as fatigue, weakness, body aches, and dizziness. Your doctor will gradually reduce the dose before completely stopping the medication. If you experience any unusual symptoms or side effects, consult your doctor immediately.
  • Inform your doctor or dentist that you are taking DEFCORT TM TABLET 10'S before undergoing any surgery or dental procedure. This medication can affect your body's response to stress, and your doctor may need to adjust your dosage accordingly.
  • Avoid contact with people who have contagious illnesses, such as chickenpox or measles, while taking DEFCORT TM TABLET 10'S. This medication can weaken your immune system, making you more susceptible to infections. If you are exposed to any contagious illnesses, inform your doctor immediately.
  • Store DEFCORT TM TABLET 10'S at room temperature, away from heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets. Dispose of any unused or expired medication properly. Ask your pharmacist about proper disposal methods.

Quick Tips for DEFCORT TM TABLET 10'SArrow

  • Take Defcort TM Tablet exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures optimal effectiveness and minimizes potential side effects. This medication is typically prescribed to manage inflammation, allergic reactions, and autoimmune disorders. Understanding its specific purpose in your case is vital for monitoring its effects and reporting any unusual symptoms to your healthcare provider.
  • It is best to take Defcort TM Tablet with food or milk to reduce the likelihood of stomach upset. If you experience persistent indigestion or nausea, inform your doctor. Consistent timing of doses each day helps maintain a steady level of the medicine in your system, maximizing its benefits. Try to take it at the same time every day as prescribed by your doctor for the best results.
  • If you are taking Defcort TM Tablet for an extended period, do not stop it abruptly. Sudden cessation can lead to withdrawal symptoms or a flare-up of the underlying condition. Your doctor will gradually reduce the dosage to allow your body to adjust. Long-term use of Defcort TM Tablet can affect your immune system. Be vigilant about hygiene practices, and avoid contact with individuals who are ill. Report any signs of infection, such as fever, sore throat, or cough, to your doctor immediately.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking, as Defcort TM Tablet can interact with certain substances. This is especially important for individuals with pre-existing medical conditions such as diabetes, high blood pressure, or osteoporosis. Steroid medicines like Defcort TM Tablet can sometimes affect mood. If you experience significant mood changes, such as depression, anxiety, or irritability, discuss them with your doctor. Do not get vaccinated without consulting your doctor.
  • While taking Defcort TM Tablet, it's important to maintain a healthy lifestyle. This includes a balanced diet, regular exercise, and adequate sleep. A diet rich in calcium and vitamin D can help minimize the risk of bone thinning, a potential side effect of long-term steroid use. Discuss any concerns you have about the medicine with your doctor or pharmacist. They can provide personalized advice and address any questions you may have. Always keep your follow-up appointments to monitor your health and medicine effectiveness.

Food Interactions with DEFCORT TM TABLET 10'SArrow

  • DEFCORT TM TABLET 10'S can be taken with or without food. However, taking it with food may help to reduce stomach upset. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it can increase the level of the drug in your body and potentially increase side effects. Maintain a consistent diet during treatment.

FAQs

What is DEFCORT TM TABLET 10'S and what is it used for?Arrow

DEFCORT TM TABLET 10'S contains deflazacort, which is a corticosteroid. It is used to treat a variety of conditions including inflammation, allergies, and autoimmune diseases.

How does DEFCORT TM TABLET 10'S work?Arrow

DEFCORT TM TABLET 10'S works by reducing inflammation in the body. It also suppresses the activity of the immune system, which helps in treating autoimmune diseases.

What are the common side effects of DEFCORT TM TABLET 10'S?Arrow

Common side effects of DEFCORT TM TABLET 10'S include weight gain, increased appetite, mood changes, trouble sleeping, and stomach upset.

Is DEFCORT TM TABLET 10'S safe for children?Arrow

DEFCORT TM TABLET 10'S should be used with caution in children and only under the guidance of a doctor. It can affect the growth of children.

How should I store DEFCORT TM TABLET 10'S?Arrow

Store DEFCORT TM TABLET 10'S at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can DEFCORT TM TABLET 10'S be taken with or without food?Arrow

DEFCORT TM TABLET 10'S can be taken with or without food, but it is best to take it with food to minimize stomach irritation.

Does DEFCORT TM TABLET 10'S interact with other medications?Arrow

DEFCORT TM TABLET 10'S can interact with certain medications, such as anticoagulants, antidiabetic drugs, and some vaccines. Tell your doctor about all the medications you are taking.

What are the symptoms of an overdose of DEFCORT TM TABLET 10'S?Arrow

Symptoms of an overdose of DEFCORT TM TABLET 10'S may include confusion, anxiety, depression, stomach pain, and vomiting. Seek immediate medical attention if you suspect you have taken an overdose.

Is it safe to drink alcohol while taking DEFCORT TM TABLET 10'S?Arrow

You should avoid drinking alcohol while taking DEFCORT TM TABLET 10'S, as it can increase the risk of stomach irritation and other side effects.

What are the alternatives to DEFCORT TM TABLET 10'S?Arrow

Alternatives to DEFCORT TM TABLET 10'S include other corticosteroids such as prednisone or methylprednisolone. Your doctor can determine the most appropriate alternative for your condition.

Can I take DEFCORT TM TABLET 10'S during pregnancy?Arrow

Consult your doctor before taking DEFCORT TM TABLET 10'S during pregnancy. It may harm the fetus.

Can I take DEFCORT TM TABLET 10'S while breastfeeding?Arrow

Consult your doctor before taking DEFCORT TM TABLET 10'S while breastfeeding. It may pass into breast milk and harm the baby.

What is the difference between deflazacort and prednisolone?Arrow

Deflazacort and prednisolone are both corticosteroids, but deflazacort is thought to have less impact on bones. Your doctor can determine the most appropriate medication for your condition.

Is DEFCORT TM TABLET 10'S a steroid?Arrow

Yes, DEFCORT TM TABLET 10'S is a corticosteroid, which is commonly known as a steroid.

How long should I take DEFCORT TM TABLET 10'S?Arrow

The duration of taking DEFCORT TM TABLET 10'S depends on your condition and the doctor's instructions. Do not stop taking the medicine without consulting your doctor.

References

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DrugBank: Deflazacort. This entry provides comprehensive pharmaceutical information, including mechanism of action, uses, and pharmacology, which could relate to DEFCORT due to its deflazacort content.

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FDA Label for EMFLAZA (deflazacort) tablets. This is the FDA label for a deflazacort product, providing detailed information on its use, dosage, and safety.

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PubChem: Deflazacort. Chemical information, structure, properties, and safety data are provided.

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European Medicines Agency (EMA) EPAR for EMFLAZA. Provides regulatory and scientific information about deflazacort.

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PubMed Central. Search for research articles related to deflazacort. Use search terms like 'deflazacort clinical trials' or 'deflazacort pharmacology'.

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MACLEODS PHARMACEUTICALS PRIVATE LIMITED

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