DEMELAN CREAM 20 GM

How DEMELAN CREAM 20 GM Works

• Demelan Cream 20 gm is a topical treatment formulated to address hyperpigmentation, a condition characterized by dark patches or spots on the skin. Its effectiveness stems from a combination of three active ingredients: Glycolic acid, Arbutin, and Kojic acid, each contributing through a distinct mechanism to lighten skin and even out skin tone.
• Glycolic acid, an alpha-hydroxy acid (AHA), acts as an exfoliant. It weakens the bonds between dead skin cells on the surface, promoting their shedding. This process reveals newer, brighter skin underneath. By removing the pigmented, dead cells, glycolic acid helps to fade dark spots, melasma, and post-inflammatory hyperpigmentation. Furthermore, this exfoliation enhances the penetration of the other active ingredients, Arbutin and Kojic acid, maximizing their efficacy.
• Arbutin is a naturally derived skin-lightening agent. Its primary function is to inhibit tyrosinase, an enzyme crucial in the production of melanin. Melanin is the pigment responsible for skin color, and its overproduction leads to hyperpigmentation. By blocking tyrosinase, Arbutin reduces melanin synthesis, effectively lightening existing dark spots and preventing the formation of new ones. Arbutin is considered a safer alternative to hydroquinone, another skin-lightening agent, as it's less likely to cause irritation or adverse effects.
• Kojic acid, derived from fungi, also inhibits melanin production, though through a different mechanism than Arbutin. Kojic acid chelates copper, an essential cofactor for tyrosinase activity. By binding to copper, Kojic acid effectively inactivates tyrosinase, hindering melanin synthesis. This dual action, with both Arbutin and Kojic acid targeting tyrosinase, provides a synergistic approach to reducing hyperpigmentation.
• In summary, Demelan Cream works by exfoliating the skin's surface with glycolic acid, removing pigmented cells and enhancing the penetration of Arbutin and Kojic acid. Arbutin and Kojic acid then inhibit melanin production through different pathways, preventing further hyperpigmentation and lightening existing dark spots. Regular use of Demelan Cream, as directed by a healthcare professional, can lead to a visible improvement in skin tone and a reduction in hyperpigmentation over time. It's essential to use sunscreen alongside Demelan Cream, as the newly exposed skin is more susceptible to sun damage.

Demelan Cream, like other topical medications, can cause side effects, although not everyone experiences them. Common side effects may include: * **Burning or stinging sensation:** A temporary burning or stinging feeling upon application. * **Redness:** The skin may become red or inflamed. * **Dryness:** The skin may become dry, flaky, or peel. * **Itching:** Mild to moderate itching at the application site. * **Irritation:** General skin irritation. Less common, but more serious side effects can include: * **Blistering:** Formation of blisters on the skin. * **Swelling:** Swelling of the treated area. * **Hyperpigmentation:** Darkening of the skin. * **Hypopigmentation:** Lightening of the skin. * **Allergic reactions:** Rash, hives, itching, swelling, dizziness, or difficulty breathing. **Important Considerations:** * If any of these side effects become severe or persistent, discontinue use and consult a doctor. * Avoid prolonged sun exposure while using Demelan Cream, as it can increase sensitivity to the sun. * Use sunscreen regularly. * Inform your doctor about any other medications or skin conditions you have before using Demelan Cream.

• If you miss a dose of Demelan Cream, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for the one you missed.

• Keep DEMELAN CREAM 20GM away from the reach of children and pets.
• Store DEMELAN CREAM 20GM at room temperature.

• Always apply Demelan Cream to clean, dry skin. Gently wash the affected area with a mild cleanser and pat dry before applying a thin layer of the cream. This ensures optimal absorption and reduces the risk of irritation.
• Use Demelan Cream sparingly. Apply only a small amount to the affected area, avoiding the surrounding skin. Overapplication can increase the likelihood of side effects such as redness, peeling, or dryness. A pea-sized amount is generally sufficient for a small area.
• Consistency is key with Demelan Cream. For best results, apply the cream regularly as directed by your doctor or as indicated in the product instructions. Missing applications can slow down the progress and reduce the effectiveness of the treatment. Usually, this means applying it once daily, typically at night.
• Protect your skin from sun exposure while using Demelan Cream. This cream can make your skin more sensitive to the sun, increasing the risk of sunburn and hyperpigmentation. Always wear a broad-spectrum sunscreen with an SPF of 30 or higher during the day, even on cloudy days. Reapply sunscreen every two hours, especially if you are sweating or swimming. Additionally, consider wearing protective clothing and seeking shade when possible.
• Be patient and manage expectations. Improvement in skin conditions like melasma or hyperpigmentation can take several weeks or even months of consistent use. Do not expect overnight results. If you experience any significant irritation or adverse reactions, discontinue use and consult your doctor or dermatologist.
• Avoid using other potentially irritating topical products while using Demelan Cream, unless specifically directed by your doctor. This includes products containing benzoyl peroxide, salicylic acid, or alcohol. Combining these products can lead to excessive dryness, redness, and irritation.
• Store Demelan Cream properly. Keep the cream in a cool, dry place away from direct sunlight and heat. Ensure the tube is tightly closed to prevent oxidation and maintain its effectiveness. Do not store it in the bathroom, where humidity can affect its stability.
• Inform your doctor about all other medications and skincare products you are using. Certain medications or products may interact with Demelan Cream, potentially affecting its efficacy or increasing the risk of side effects. Provide a complete list to ensure your doctor can make informed recommendations.
• If you are pregnant or breastfeeding, consult your doctor before using Demelan Cream. The safety of this cream during pregnancy and breastfeeding has not been definitively established, so it is crucial to seek medical advice before use.
• Monitor your skin for any signs of irritation or allergic reaction. Common side effects may include mild redness, peeling, or dryness. However, if you experience severe burning, itching, swelling, or blistering, discontinue use immediately and seek medical attention.

• There are no known interactions between Demelan Cream 20 gm and food. Demelan Cream is for external use only, and its absorption into the bloodstream is minimal. Therefore, it is unlikely to be affected by the consumption of any food or drink.