DENOSUREL 120MG INJECTION
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DENOSUREL 120MG INJECTION
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DENOSUREL 120MG INJECTION

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DENOSUREL 120MG INJECTION

By RELIANCE LIFE SCIENCES

MRP

34485

₹14829

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Product DetailsArrow

About DENOSUREL 120MG INJECTION

  • DENOSUREL 120MG INJECTION contains the active ingredient Denosumab. This medication is primarily used to treat osteoporosis, a condition characterized by weakened and brittle bones, making them more susceptible to fractures. It is also prescribed to prevent skeletal-related events (SREs) in patients with certain cancers that have metastasized to the bone, such as multiple myeloma and bone metastases from solid tumors. By preventing bone loss and reducing the risk of fractures and other bone complications, DENOSUREL 120MG INJECTION helps to improve the quality of life for individuals at risk of or affected by these conditions.
  • DENOSUREL 120MG INJECTION functions by targeting and inhibiting a protein known as RANK ligand (RANKL). RANKL plays a crucial role in the formation, function, and survival of osteoclasts, which are cells responsible for breaking down bone tissue. By binding to RANKL, Denosumab prevents it from activating its receptor, RANK, on the surface of osteoclasts. This action effectively slows down bone resorption, allowing bone density to increase over time. Clinical studies have demonstrated that DENOSUREL 120MG INJECTION can significantly improve bone mineral density (BMD) and reduce the incidence of fractures in postmenopausal women with osteoporosis, as well as in patients experiencing bone loss due to cancer treatments.
  • Before using DENOSUREL 120MG INJECTION, it's important to inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. This medication is contraindicated in individuals with a known hypersensitivity or allergic reaction to Denosumab or any of the other components in the injection. Patients should maintain adequate calcium and vitamin D levels during treatment to support bone health and prevent hypocalcemia. Close monitoring of kidney function may be necessary for patients with moderate renal impairment. DENOSUREL 120MG INJECTION is not approved for use in children and adolescents, as its safety and effectiveness in these populations have not been established. Caution should be exercised when using this medication in individuals with pre-existing hypoparathyroidism, a condition characterized by low parathyroid hormone levels.

Uses of DENOSUREL 120MG INJECTION

  • DENOSUREL 120MG INJECTION is used in the treatment of the following condition: Osteoporosis, a condition where bones become weak and brittle, increasing the risk of fractures.
  • Bone loss due to hormonal therapy in breast or prostate cancer: DENOSUREL 120MG INJECTION helps to prevent bone loss caused by cancer treatment.
  • Multiple myeloma (cancer affects plasma cells in the bone marrow): DENOSUREL 120MG INJECTION can help manage bone-related problems in people with multiple myeloma.
  • Bone metastases (cancer that spreads to bone): DENOSUREL 120MG INJECTION is used to help prevent or delay complications related to bone metastases in people whose cancer has spread to the bone.

Side Effects of DENOSUREL 120MG INJECTIONArrow

Like all medications, DENOSUREL 120MG INJECTION can cause side effects, although not everyone who takes it will experience them.

  • Osteonecrosis of the jaw (severe necrosis or death of jaw cells)
  • Atypical femoral fractures
  • Hypocalcemia (low blood calcium levels)
  • Injection site reactions
  • Back pain
  • Musculoskeletal pain
  • Infections
  • Abdominal pain
  • Headache
  • Hypophosphatemia (low blood phosphate levels)

Safety Advice for DENOSUREL 120MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

The safety of using DENOSUREL 120MG INJECTION during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Dosage of DENOSUREL 120MG INJECTIONArrow

  • DENOSUREL 120MG INJECTION is administered via injection by qualified healthcare professionals. This ensures the medication is delivered correctly and safely, maximizing its effectiveness and minimizing potential risks.
  • The specific dosage and the length of the treatment period are carefully determined by the healthcare provider, taking into account the patient's unique medical condition, the severity of their osteoporosis, and their individual response to the medication. Regular monitoring is crucial to assess the treatment's impact and make any necessary adjustments to the dosage schedule.
  • It's essential to adhere strictly to the healthcare provider's instructions regarding the frequency and timing of injections. Self-administration of DENOSUREL 120MG INJECTION is not recommended. Any concerns or questions about the treatment plan should be promptly discussed with the healthcare provider to ensure optimal outcomes and address any potential side effects.
  • The information provided here is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for diagnosis and treatment of any medical condition.

How to store DENOSUREL 120MG INJECTION?Arrow

  • Keep DENOSUREL 120MG INJ 1.7ML away from the reach of children and pets.
  • Store DENOSUREL 120MG INJ 1.7ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of DENOSUREL 120MG INJECTIONArrow

  • DENOSUREL 120MG INJECTION is a powerful medication designed to significantly improve bone health and reduce the risk of fractures. Its therapeutic effects stem from its ability to inhibit bone resorption, a process where old bone tissue is broken down and removed by the body. By targeting RANK ligands, key proteins involved in this process, DENOSUREL 120MG INJECTION effectively slows down bone resorption, allowing new bone formation to catch up and leading to stronger, denser bones.
  • One of the primary benefits of DENOSUREL 120MG INJECTION is its ability to increase bone mineral density (BMD). BMD is a crucial indicator of bone strength, and higher BMD levels are associated with a lower risk of fractures. Clinical studies have shown that DENOSUREL 120MG INJECTION can significantly increase BMD in various areas of the body, including the spine and hip, which are common sites for osteoporotic fractures.
  • The combined effect of reduced bone resorption and increased BMD translates to a substantial reduction in fracture risk. DENOSUREL 120MG INJECTION is particularly beneficial for individuals with osteoporosis, a condition characterized by weakened bones and increased susceptibility to fractures. It is also suitable for individuals at high risk of fractures due to other factors, such as age, family history, or certain medical conditions. Ultimately, the therapeutic effects of DENOSUREL 120MG INJECTION contribute to improved bone health, reduced fracture risk, and an enhanced quality of life for patients.

How to use DENOSUREL 120MG INJECTIONArrow

  • DENOSUREL 120MG INJECTION is administered via injection by qualified healthcare professionals. This ensures the medication is given safely and effectively, minimizing potential complications and maximizing its therapeutic benefits.
  • The precise dosage and the length of the treatment will be determined by your healthcare provider. These factors depend heavily on your specific medical condition, its severity, and your body's response to the treatment. Regular monitoring and evaluation are crucial to tailor the treatment plan to your individual needs.
  • It is crucial to adhere strictly to the schedule provided by your doctor. Do not attempt to adjust the dosage or frequency of injections without consulting them first. Self-adjusting medication can lead to serious health consequences. Proper administration and adherence to your healthcare provider's instructions are essential for optimal results and to minimize the risk of adverse effects.
  • If you have any questions or concerns regarding the administration of DENOSUREL 120MG INJECTION, don't hesitate to seek clarification from your healthcare provider. They can provide detailed explanations and address any anxieties you may have about the treatment process.

FAQs

Can DENOSUREL 120MG INJECTION be used in patients with a history of cancer?Arrow

DENOSUREL 120MG INJECTION is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.

Can DENOSUREL 120MG INJECTION be used in patients with kidney problems?Arrow

DENOSUREL 120MG INJECTION is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.

Can DENOSUREL 120MG INJECTION be used as a treatment for osteoporosis in men?Arrow

Yes, DENOSUREL 120MG INJECTION is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.

Can DENOSUREL 120MG INJECTION be used in children and adolescents with osteoporosis?Arrow

DENOSUREL 120MG INJECTION is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.

Can DENOSUREL 120MG INJECTION be used in individuals with dental implants?Arrow

DENOSUREL 120MG INJECTION use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess DENOSUREL 120MG INJECTION's potential risks and benefits.

What Are the Side Effects of DENOSUREL 120MG INJECTION?Arrow

DENOSUREL 120MG INJECTION can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.

NULL interaction of DENOSUREL 120MG INJECTION with other drungsArrow

There are no known interactions of DENOSUREL 120MG INJECTION with other drugs.

What advice should I follow while taking DENOSUREL 120MG INJECTION?Arrow

Attend all scheduled appointments and follow-up visits to monitor your response to treatment and address any concerns or side effects. Tell your doctor about your medical history, previous infection, liver disease, and kidney disease. Inform your healthcare provider about any allergies or hypersensitivity reactions you may have. Seek immediate medical attention if you experience severe allergic reactions or other serious side effects. Additionally, Denosurel 120mg Injection may affect calcium levels, so monitoring calcium levels and ensuring adequate calcium and vitamin D intake is important. Pregnant and breastfeeding women should consult a doctor before taking this medication. Avoid taking any vaccines during treatment. Regular dental examinations and good oral hygiene practices are recommended to minimize the risk of jaw osteonecrosis.

What molecule/combination is used for making DENOSUREL 120MG INJECTION?Arrow

DENOSUMAB is molecule/combination used for making DENOSUREL 120MG INJECTION.

For which ailments/diseases/conditions is DENOSUREL 120MG INJECTION prescribed?Arrow

DENOSUREL 120MG INJECTION is prescribed for ailments/diseases/conditions related to Rheumatology, Orthopaedics, and Gastroenterology.

References

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Amgen Ltd, Electronic medicines compendium (EMC)

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Amgen Manufacturing Limited, US Food and Drug Administration

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Amgen Manufacturing Limited, US Food and Drug Administration

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Discount on medicine is good But OTC discount is zero and very low

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Reviewed on 05-12-2022

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khozema kaukawala

Reviewed on 08-09-2023

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(5/5)

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Reviewed on 23-01-2024

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Reviewed on 18-05-2023

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(5/5)


Marketer / Manufacturer Details

RELIANCE LIFE SCIENCES

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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