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Content Reviewed By:
Dr. Rajesh Sharma
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Common side effects of Deriphyllin Injection may include nausea, vomiting, epigastric pain, headache, insomnia, dizziness, palpitations, and mild diuresis. Less common but more serious side effects can include allergic reactions (rash, itching, swelling), seizures, and cardiac arrhythmias. Rapid intravenous administration may cause flushing, hypotension, and anxiety. Rarely, it can cause liver problems or blood disorders. Consult your doctor if you experience any persistent or severe side effects.
Pregnancy
Use only if clearly neededDeriphyllin injection should be used during pregnancy only when the potential benefit to the mother justifies the possible risk to the fetus, and when alternative treatments are not suitable or adequate.
BreastFeeding
Use with cautionTheophylline is excreted into breast milk and may reach levels that can cause irritability, poor sleep, or feeding difficulties in some breastfed infants, especially if maternal serum levels are high.
Driving
May impair abilityDeriphyllin injection can cause side effects such as dizziness, headache, tremor, restlessness, or, rarely, confusion and seizures, which may impair the ability to drive or operate machinery.
Alcohol
Avoid or limitAlcohol consumption can alter the metabolism of theophylline and may either increase or decrease its blood levels, leading to reduced efficacy or increased risk of toxicity.
Allergies
Contraindicated in hypersensitivityDeriphyllin injection is contraindicated in patients with known hypersensitivity to theophylline, etofylline, other xanthine derivatives, or any component of the formulation.
Deriphyllin injection is used for the short-term management of acute episodes of reversible airway obstruction, such as acute exacerbations of bronchial asthma and chronic obstructive pulmonary disease (COPD). It provides rapid bronchodilation when oral medicines or inhalers are insufficient, not tolerated, or cannot be used. It is usually administered in hospital or emergency settings under close medical supervision.
Deriphyllin injection contains etofylline and theophylline, which are xanthine derivatives. They inhibit phosphodiesterase enzymes, leading to increased levels of cyclic AMP in bronchial smooth muscle cells. This causes relaxation of the airway smooth muscles and bronchodilation, improving airflow and relieving symptoms like wheezing and breathlessness. Theophylline may also stimulate the respiratory center and have mild diuretic and cardiac stimulant effects.
No, Deriphyllin injection is not a steroid. It is a bronchodilator containing xanthine derivatives (etofylline and theophylline). While it helps open the airways, it does not have the anti-inflammatory properties of corticosteroids. In acute asthma or COPD exacerbations, it is often used in addition to inhaled or systemic corticosteroids, not as a substitute for them.
Deriphyllin injection is not intended for routine treatment of all types of cough or breathlessness. It is specifically used for reversible airway obstruction, such as in asthma or COPD exacerbations, and only when clinically indicated. Breathlessness due to heart failure, pneumonia, pulmonary embolism, or other non-obstructive causes requires different treatment. A doctor must evaluate the underlying cause before deciding whether Deriphyllin injection is appropriate.
Common side effects include nausea, vomiting, abdominal discomfort, headache, dizziness, restlessness, irritability, tremor, palpitations, and difficulty sleeping. Some patients may experience flushing or a feeling of warmth. These effects are often related to theophylline levels in the blood. If side effects are severe or persistent, or if symptoms such as severe vomiting, chest pain, rapid or irregular heartbeat, or seizures occur, urgent medical attention is required.
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India

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