DESFERAL 500MG INJECTION
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DESFERAL 500MG INJECTION
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DESFERAL 500MG INJECTION

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DESFERAL 500MG INJECTION

By NOVARTIS INDIA LIMITED

MRP

₹

205.86

₹205.86

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Product DetailsArrow

About DESFERAL 500MG INJECTION

  • DESFERAL 500MG INJECTION contains deferoxamine as an active component. This medication is used to treat iron overload in the body and belongs to a class of drugs called iron-chelating agents. Iron overload diseases include thalassemia, hemochromatosis, sickle cell disease, myelodysplastic syndromes, chronic transfusions, and iron poisoning. Thalassemia is an inherited blood disorder causing abnormal hemoglobin production and anemia. Hemochromatosis is a hereditary condition with excessive iron absorption, leading to iron overload in organs. Sickle cell disease is a genetic disorder affecting red blood cell shape, causing pain and organ damage. Myelodysplastic syndromes are blood disorders affecting the bone marrow, leading to abnormal blood cell production. Chronic transfusions are required for severe anemia or blood disorders, leading to iron overload. Iron poisoning occurs when toxic amounts of iron are ingested and treated with DESFERAL 500MG INJECTION to eliminate excess iron from the body. Iron overload can occur in conditions such as thalassemia, hemochromatosis, or chronic transfusions, where excessive iron accumulates in organs and tissues, potentially causing damage.
  • By managing iron overload, DESFERAL 500MG INJECTION can improve the quality of life for individuals with conditions that cause iron accumulation. It may help reduce symptoms like fatigue, joint pain, and other complications associated with iron overload. Properly managing iron overload with this medication can help prolong the life expectancy of individuals with iron-related disorders by preventing severe organ damage and complications. Iron overload can lead to serious complications like liver disease, heart problems, and endocrine disorders. By reducing excess iron levels, it helps lower the risk of such complications. In addition to its therapeutic benefits, DESFERAL 500MG INJECTION is also crucial in diagnostic procedures to assess iron storage levels in the body.
  • Individuals with a known allergy to DESFERAL 500MG INJECTION or any of its components should not use this medication. Allergic reactions can range from mild skin rashes to severe anaphylactic reactions, which can be life-threatening. This is primarily excreted by the kidneys. Patients with significant kidney impairment may not be suitable candidates for DESFERAL 500MG INJECTION therapy or may require dosage adjustments and close monitoring. This medication has been associated with potential hearing and vision disturbances in some patients. Individuals with pre-existing hearing or vision problems should be cautious and may require more frequent monitoring. It is not suitable for treating iron deficiency anemia. It can exacerbate iron deficiency, so it should not be used in individuals with low iron levels. While this medication can be used in pediatric patients, careful monitoring and appropriate dosage adjustments based on weight and individual needs are essential. It's also important to consider potential interactions with other medications and supplements. Regular blood tests are necessary to monitor iron levels and assess the effectiveness of the treatment.

Uses of DESFERAL 500MG INJECTION

  • DESFERAL 500MG INJECTION is used in the treatment of the following:
  • Thalassemia
  • Hemochromatosis
  • Sickle cell disease
  • Myelodysplastic syndromes
  • Chronic transfusions
  • Iron poisoning

Side Effects of DESFERAL 500MG INJECTIONArrow

Like all medications, DESFERAL 500MG INJECTION causes some side effects, although not everyone will experience them.

  • Tightness of chest with wheezing or coughing and difficulty in breathing
  • Allergic reactions (facial and throat swelling, feeling faint, rash)
  • Decreased urine output
  • Seizures
  • Infections (fever accompanied by stomach pain and shortness of breath)
  • Pain, swelling, redness, and itching at the injection site
  • Headache
  • Reddish-brown color of urine
  • Nausea
  • Fever, feeling sick
  • Slow growth in children under age three

Safety Advice for DESFERAL 500MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

DESFERAL 500MG INJECTION use during pregnancy with caution and only used after consulting a healthcare provider.

Dosage of DESFERAL 500MG INJECTIONArrow

  • Healthcare professionals typically administer DESFERAL 500MG INJECTION in a hospital or clinical setting, ensuring a controlled and monitored environment. The method of administration, whether intravenous (IV) or subcutaneous injection, depends on the specific treatment condition, the severity of iron overload, and the healthcare provider's detailed instructions. Prior to the administration of DESFERAL 500MG INJECTION, a healthcare professional will conduct a thorough assessment of the patient's medical history, paying close attention to any pre-existing conditions, current health status, and a detailed list of any known allergies or sensitivities to medications or other substances.
  • This comprehensive evaluation is crucial to minimize the risk of adverse reactions and to tailor the treatment plan to the individual patient's needs. Furthermore, healthcare providers carefully calculate the dosage of DESFERAL 500MG INJECTION based on factors such as the patient's body weight, the degree of iron overload as determined by laboratory tests like serum ferritin levels, and the patient's kidney function. Regular monitoring during treatment is essential to assess the drug's effectiveness and make any necessary dosage adjustments to achieve optimal therapeutic outcomes while minimizing potential side effects. Patients should openly communicate with their healthcare team about any concerns or changes in their health status during the course of treatment.
  • The selection of the administration route considers patient comfort, convenience, and adherence to the prescribed treatment schedule. IV administration may be preferred for rapid iron chelation or in patients with severe iron overload, while subcutaneous injections, which can be administered over a longer period, may be suitable for less severe cases or for maintenance therapy. The decision regarding the administration route and dosage is always made in consultation with a qualified healthcare professional.

How to store DESFERAL 500MG INJECTION?Arrow

  • Keep DESFERAL 500MG INJ away from the reach of children and pets.
  • Store DESFERAL 500MG INJ at room temperature.

Benefits of DESFERAL 500MG INJECTIONArrow

  • DESFERAL 500MG INJECTION works by a process called chelation. Imagine it as a tiny magnet that specifically attracts and binds to extra iron floating around in your body. It grabs onto these excess iron ions, especially the trivalent (3+) form, and forms very stable, water-soluble compounds. Think of it like packaging the iron up so it can be easily disposed of.
  • Once the iron is bound to DESFERAL 500MG INJECTION, forming what's called an iron-deferoxamine complex, your body can get rid of it. The primary route of elimination is through your urine. So, the medication helps to flush out the excess iron, effectively reducing iron levels in your blood and the tissues of your organs.
  • By lowering the amount of free iron in your system, DESFERAL 500MG INJECTION helps to protect your organs and tissues from damage. Excess iron can cause oxidative damage, similar to how rust affects metal. This medication helps prevent that damage, reducing the risk of organ problems and other complications linked to iron overload, which can occur in conditions like thalassemia, hemochromatosis, and when someone requires frequent blood transfusions. Ultimately, it helps maintain the health and function of vital organs.

How to use DESFERAL 500MG INJECTIONArrow

  • Typically, healthcare professionals administer DESFERAL 500MG INJECTION in a controlled hospital or clinical environment to ensure patient safety and proper monitoring. The method of administration, whether intravenous (IV) infusion, intramuscular (IM) injection, or subcutaneous (SC) infusion, depends on the specific treatment protocol and the healthcare provider's professional judgment.
  • Prior to administering DESFERAL 500MG INJECTION, a healthcare professional will thoroughly evaluate the patient's complete medical history, encompassing current health status, pre-existing medical conditions, and any documented allergies or sensitivities to medications. This comprehensive assessment is crucial to minimize potential risks and ensure the patient's safety.
  • The dosage and duration of treatment with DESFERAL 500MG INJECTION are individualized and carefully determined by the healthcare provider based on factors such as the patient's weight, the severity of iron overload, and their response to therapy. Regular monitoring of iron levels and overall health status is essential throughout the treatment course to optimize therapeutic outcomes and manage potential side effects.

FAQs

What are the common side effects of DESFERAL 500MG INJECTION?Arrow

Common side effects of DESFERAL 500MG INJECTION may include gastrointestinal disturbances (nausea, vomiting, diarrhea), injection site reactions, dizziness, and headache.

Can DESFERAL 500MG INJECTION cause kidney problems?Arrow

DESFERAL 500MG INJECTION may affect kidney function in some patients, especially those with pre-existing kidney problems. Regular monitoring of kidney function is essential during treatment.

Is DESFERAL 500MG INJECTION safe for children?Arrow

DESFERAL 500MG INJECTION is generally well-tolerated in children, but appropriate dosage and monitoring are crucial, especially in pediatric patients.

How long is DESFERAL 500MG INJECTION treatment usually required?Arrow

The duration of DESFERAL 500MG INJECTION treatment depends on the severity of iron overload and the patient's response to therapy. Some individuals may require lifelong treatment, while others may need it for a specific period.

Can DESFERAL 500MG INJECTION lead to iron deficiency?Arrow

While DESFERAL 500MG INJECTION is used to treat iron overload conditions, it may also lead to iron deficiency if not appropriately managed. Regular monitoring of iron levels is necessary to maintain a proper iron balance.

Can DESFERAL 500MG INJECTION cause changes in vision or hearing?Arrow

Yes, DESFERAL 500MG INJECTION may cause visual and auditory disturbances, such as blurred vision or hearing loss, in some individuals.

Are there any known drug interactions with DESFERAL 500MG INJECTION?Arrow

There are no known negative interactions of DESFERAL 500MG INJECTION with other drugs.

What precautions should I take while using DESFERAL 500MG INJECTION?Arrow

It is essential to inform your healthcare provider about any pre-existing medical conditions, allergies, or medications you are taking to avoid potential drug interactions or contraindications. Regular monitoring of iron levels, kidney function, and blood counts is crucial during treatment to ensure appropriate dosing and to detect any adverse effects promptly. If you experience any signs of allergic reactions, visual or hearing changes, difficulty breathing, or severe skin reactions, seek immediate medical attention. Take caution while driving or operating machinery, especially if you experience dizziness or headaches. Abrupt discontinuation of medication may lead to a rebound increase in iron levels, potentially exacerbating iron overload. Pregnant or breastfeeding individuals should discuss the potential risks with their healthcare provider before initiating treatment. Finally, adherence to the prescribed treatment plan and close communication with your healthcare team will help optimise the safety and effectiveness of DESFERAL 500MG INJECTION therapy.

What is DESFERAL 500MG INJECTION made of?Arrow

DESFERAL 500MG INJECTION is made of Deferoxamine.

For what type of conditions is DESFERAL 500MG INJECTION prescribed?Arrow

DESFERAL 500MG INJECTION is prescribed for Hematology conditions.

References

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Novartis Pharmaceuticals UK Ltd, Electronic medicines compendium (EMC)

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Novartis, US Food and Drug Administration

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DESFERAL 500MG INJECTION

DESFERAL 500MG INJECTION

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