DIPROBATE PLUS 30 GM

How DIPROBATE PLUS 30 GM Works

• DIPROBATE PLUS 30 GM is a potent topical medication combining the anti-inflammatory, antipruritic, and vasoconstrictive effects of betamethasone dipropionate with the broad-spectrum antibacterial and antifungal properties of gentamicin and clotrimazole. This multi-pronged approach effectively targets a wide range of skin conditions complicated by bacterial or fungal infections.
• Betamethasone dipropionate, a corticosteroid, works by reducing inflammation, itching, and redness. At the cellular level, it inhibits the release of inflammatory mediators such as prostaglandins and leukotrienes. These mediators are key players in the inflammatory cascade, responsible for the characteristic symptoms of skin irritation. By blocking their production, betamethasone dipropionate effectively suppresses the body's inflammatory response in the affected area. It also acts as a vasoconstrictor, narrowing blood vessels in the skin, further reducing redness and swelling.
• Gentamicin, an aminoglycoside antibiotic, combats bacterial infections by interfering with bacterial protein synthesis. It binds to the 30S ribosomal subunit of bacteria, disrupting the process of translating genetic code into functional proteins. This disruption is lethal to bacteria, preventing them from growing and multiplying. Gentamicin is effective against a wide range of Gram-negative bacteria commonly found in skin infections, such as Staphylococcus aureus and Streptococcus pyogenes.
• Clotrimazole, an antifungal agent, targets fungal infections by disrupting the integrity of the fungal cell membrane. It inhibits the synthesis of ergosterol, a crucial component of the fungal cell membrane. Without ergosterol, the cell membrane becomes permeable and leaky, leading to cell death. Clotrimazole is effective against a variety of fungi, including dermatophytes (such as Trichophyton, Epidermophyton, and Microsporum) and yeasts (such as Candida).
• The combined action of these three active ingredients makes DIPROBATE PLUS 30 GM a highly effective treatment for various skin conditions. Betamethasone dipropionate reduces inflammation and relieves itching, while gentamicin eliminates bacterial infections, and clotrimazole eradicates fungal infections. This synergistic effect provides comprehensive relief and promotes healing in affected areas. It is important to use DIPROBATE PLUS 30 GM as directed by a healthcare professional to ensure optimal results and minimize the risk of side effects. Avoid prolonged use or application to large areas of the body without medical supervision.

Like all medicines, DIPROBATE PLUS 30 GM can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Burning * Itching * Irritation * Dryness * Redness at the application site **Uncommon Side Effects (may affect up to 1 in 100 people):** * Folliculitis (inflammation of hair follicles) * Hypertrichosis (excessive hair growth) * Acneiform eruptions (acne-like rash) * Hypopigmentation (loss of skin color) * Perioral dermatitis (red, bumpy rash around the mouth) * Allergic contact dermatitis * Maceration of the skin * Secondary infection * Skin atrophy (thinning of the skin) * Striae (stretch marks) * Miliaria (heat rash) **Rare Side Effects (may affect up to 1 in 1,000 people):** * Systemic effects due to absorption of the corticosteroid, such as adrenal suppression or Cushing's syndrome (more likely with prolonged use, use on large areas, or use under occlusion). **If you experience any of the following, stop using DIPROBATE PLUS 30 GM and seek immediate medical attention:** * Signs of a severe allergic reaction (e.g., rash, hives, itching, swelling, dizziness, difficulty breathing or swallowing). * Signs of infection (e.g., pus, increased redness, swelling, pain). This is not a complete list of side effects. If you experience any other unusual symptoms, consult your doctor or pharmacist.

• DIPROBATE PLUS side effects, betamethasone side effects, clotrimazole side effects, gentamicin side effects, skin cream side effects, topical steroid side effects, antifungal side effects, antibiotic side effects, burning, itching, irritation, dryness, redness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration, secondary infection, skin atrophy, striae, miliaria, adrenal suppression, Cushing's syndrome

• If you miss a dose of DIPROBATE PLUS 30 GM, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for the missed one.

• Keep DIPROBATE PLUS 30GM away from the reach of children and pets.
• Store DIPROBATE PLUS 30GM at room temperature.

• **Use as Directed:** Always use DIPROBATE PLUS 30 GM exactly as prescribed by your doctor. Read the label and any accompanying instructions carefully. Using more than prescribed or for longer than recommended can increase the risk of side effects and may not improve your condition faster.
• **Clean and Dry the Area:** Before applying DIPROBATE PLUS 30 GM, gently clean and thoroughly dry the affected area. This helps the medicine to penetrate effectively and reduces the risk of infection. Avoid using harsh soaps or scrubbing vigorously.
• **Apply a Thin Layer:** Apply a thin layer of DIPROBATE PLUS 30 GM to the affected skin and gently rub it in. Avoid applying a thick layer, as this can lead to increased absorption and potential side effects. Use just enough to cover the affected area.
• **Wash Hands After Application:** Unless you are treating your hands, always wash your hands thoroughly with soap and water after applying DIPROBATE PLUS 30 GM. This prevents the spread of the medication to other areas of your body or to other people.
• **Avoid Occlusive Dressings:** Do not cover the treated area with airtight dressings or bandages unless specifically directed by your doctor. Occlusive dressings can increase the absorption of the medication and potentially increase the risk of side effects. Loose clothing is generally preferred.
• **Monitor for Side Effects:** Pay attention to any signs of side effects, such as increased redness, itching, burning, or blistering. If you experience any concerning side effects, stop using DIPROBATE PLUS 30 GM and contact your doctor immediately. Long-term use can lead to skin thinning or other complications.
• **Store Properly:** Store DIPROBATE PLUS 30 GM in a cool, dry place, away from direct sunlight and heat. Keep it out of reach of children and pets. Proper storage helps maintain the medication's effectiveness.

• There are no known interactions between DIPROBATE PLUS 30 GM and food. DIPROBATE PLUS is for external use only, and food intake does not affect its absorption or efficacy. However, it is generally advisable to maintain a healthy diet while using any medication.