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Composition
Content Reviewed By:
Dr. Rajesh Sharma
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Other Medical Conditions and Drug Interactions
Careful review requiredDMR 30 should be used with particular caution in patients with chronic respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), or severe respiratory insufficiency. Suppressing cough in these settings may mask clinical deterioration or impair clearance of secretions.
Dextromethorphan is a decongestant and not a steroid, antihistamine, opiate, NSAID or narcotic, but can have addictive effects if taken at large doses than recommended. It does not contain codeine or alcohol. It is not a controlled substance
Dextromethorphan works for most of the patient. It should be taken in amounts exactly as directed on the label, or as prescribed by your doctor. Cough medicine is usually taken only for a short time until your symptoms clear up. Do not use the medication in larger amounts, or use it for longer than recommended
Dextromethorphan causes mild sedation effect thus can make you feel sleepy. It does not raise blood sugar or make you tired. Dextromethorphan is generally safe if taken at recommended doses and duration
Though it isn't reported, but it should be used carefully in people with high blood pressure, as dextromethorphan may cause high blood pressure and the effectiveness of dextromethorphan is decreased by high blood pressure medications
Drug interaction with any of the above mentioned drugs is not documented, but it can occur. Always follow your doctor's advice before taking any medicine with dextromethorphan.
DMR 30 is a cough suppressant tablet containing dextromethorphan hydrobromide 30 mg. It is used for short-term relief of dry, non-productive cough, typically associated with upper respiratory tract infections such as the common cold or throat irritation. It reduces the urge to cough by acting on the cough center in the brain but does not treat the underlying cause of the illness.
The active ingredient in DMR 30, dextromethorphan, acts centrally on the medullary cough center in the brain. It increases the threshold for triggering a cough, which leads to a reduction in the frequency and intensity of coughing. At recommended doses, it has minimal effect on respiratory rate and does not have significant analgesic or addictive properties compared with opioid antitussives such as codeine.
DMR 30 is generally not recommended for wet or productive cough, where mucus or phlegm is being brought up from the lungs. Suppressing a productive cough may interfere with the clearance of secretions and could potentially worsen respiratory conditions. In cases of productive cough, an evaluation by a healthcare professional is advised to determine appropriate therapy, which may include expectorants or other treatments rather than a cough suppressant.
Caution is required when using DMR 30 with antidepressants, especially monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), and certain tricyclic antidepressants. Dextromethorphan has serotonergic activity and, when combined with these medicines, may increase the risk of serotonin syndrome, a potentially serious condition characterized by agitation, confusion, sweating, tremor, and rapid heart rate. Concomitant use with MAOIs or within 14 days of stopping an MAOI is contraindicated. Patients on antidepressants should consult their doctor before taking DMR 30.
Use of DMR 30 in children depends on age, local regulatory recommendations, and the judgment of a pediatrician. Many guidelines advise caution or avoidance of dextromethorphan-containing products in very young children due to limited evidence of benefit and potential risk of adverse effects or dosing errors. Caregivers should not give DMR 30 to a child unless it has been specifically prescribed or recommended by a healthcare professional, and they should strictly follow the age-appropriate dosing instructions provided by the prescriber or product label.
Common side effects associated with dextromethorphan in DMR 30 may include mild drowsiness, dizziness, nausea, stomach discomfort, or dry mouth. These effects are usually transient and resolve when the medicine is stopped. Less commonly, allergic reactions such as rash, itching, or swelling can occur. If severe dizziness, confusion, hallucinations, difficulty breathing, or signs of an allergic reaction appear, the medicine should be discontinued and urgent medical attention sought.
Dextromethorphan can cause drowsiness, dizziness, or impaired concentration in some individuals, particularly at higher doses or when combined with alcohol or other central nervous system depressants. Until you know how DMR 30 affects you, it is advisable to avoid driving, operating heavy machinery, or performing tasks that require full alertness. If you feel sleepy, lightheaded, or mentally slowed after taking the medicine, do not engage in such activities.
Data on the use of dextromethorphan in pregnancy are limited but do not suggest a strong signal for major harm at usual therapeutic doses. However, because controlled studies are lacking, DMR 30 should be used during pregnancy only if clearly needed and after a risk–benefit assessment by a healthcare professional. Non-pharmacological measures for cough relief, such as adequate hydration and humidified air, are often preferred first. Pregnant patients should not self-medicate with DMR 30 without medical advice.
Dextromethorphan is expected to pass into breast milk in small amounts. Limited available information suggests that short-term use at recommended doses is unlikely to cause significant adverse effects in a breastfed infant, but robust data are lacking. Therefore, DMR 30 should be used with caution during breastfeeding, ideally for the shortest duration necessary and under medical supervision. Infants should be monitored for unusual sleepiness, poor feeding, or breathing difficulties, and medical advice should be sought if such symptoms occur.
Accidental intake of more than the recommended amount of DMR 30 can increase the risk of adverse effects such as marked drowsiness, dizziness, nausea, vomiting, agitation, confusion, unsteady movements, visual disturbances, or hallucinations. In severe overdose, respiratory depression, seizures, or coma may occur. If an overdose is suspected, especially in a child or an older adult, seek immediate medical attention or contact a poison control center. Do not attempt to self-treat or wait for symptoms to worsen before obtaining help.
Alcohol can enhance the sedative and psychomotor-impairing effects of dextromethorphan, increasing the risk of drowsiness, dizziness, and impaired judgment. It is advisable to avoid alcohol while taking DMR 30. In addition, many cough and cold products contain dextromethorphan or other overlapping ingredients such as antihistamines or decongestants. Taking multiple such products together can lead to unintentional overdose or increased side effects. Always check labels carefully and consult a healthcare professional before combining DMR 30 with any other over-the-counter or prescription medicines.
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