DOLENTIA MR 50/8MG TABLET 10'S

How DOLENTIA MR 50/8MG TABLET 10'S Works

• DOLENTIA MR 50/8MG TABLET 10'S is a combination medicine designed to relieve muscle spasm-related pain and discomfort. It contains two active ingredients: Diclofenac Sodium and Thiocolchicoside. Each component addresses pain and muscle stiffness through distinct mechanisms.
• Diclofenac Sodium is a non-steroidal anti-inflammatory drug (NSAID). It primarily works by inhibiting the production of prostaglandins, which are substances in the body that contribute to inflammation, pain, and fever. Diclofenac blocks cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are responsible for the synthesis of prostaglandins. By reducing prostaglandin production, Diclofenac effectively reduces inflammation, alleviates pain, and helps to lower fever if present. Its analgesic effect helps in reducing pain sensation from the affected area.
• Thiocolchicoside, on the other hand, is a muscle relaxant. It primarily acts on the gamma-aminobutyric acid (GABA) receptors in the central nervous system. It is believed to have a dual mechanism of action: it acts as a GABA-A receptor agonist and a glycine receptor agonist. By activating these receptors, thiocolchicoside enhances inhibitory neurotransmission, which helps to reduce muscle tone and relieve muscle spasm. This results in relaxation of the muscles, reducing stiffness and improving mobility. Furthermore, thiocolchicoside may also have anti-inflammatory and analgesic properties that contribute to its overall efficacy in managing muscle spasm and associated pain.
• In summary, DOLENTIA MR works synergistically by combining the anti-inflammatory and analgesic effects of Diclofenac Sodium with the muscle-relaxing properties of Thiocolchicoside. Diclofenac reduces inflammation and pain, while Thiocolchicoside relaxes the muscles, reducing stiffness and spasm. This combination provides comprehensive relief from pain, inflammation, and muscle stiffness associated with various musculoskeletal conditions.

Common side effects of Dolentia MR 50/8mg Tablet may include: Drowsiness, dizziness, headache, nausea, vomiting, stomach pain, indigestion, heartburn, dry mouth, blurred vision, constipation, difficulty in urination, muscle weakness, uncoordinated body movements and allergic reactions like skin rash, itching or hives. Uncommon side effects may include: Anxiety, confusion, sleep disturbances, palpitations, increased sweating, and changes in blood pressure. Rare side effects may include: Liver problems, kidney problems, blood disorders, and severe allergic reactions.

• If you miss a dose of DOLENTIA MR 50/8MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep DOLENTIA MR 50/8MG TAB 1X10 away from the reach of children and pets.
• Store DOLENTIA MR 50/8MG TAB 1X10 at room temperature.

• Take DOLENTIA MR 50/8MG TABLET exactly as prescribed by your doctor. Do not exceed the recommended dosage or frequency, as this can increase the risk of side effects and may not provide additional pain relief. This medication combines a pain reliever and a muscle relaxant, so it's important to follow your doctor's instructions carefully.
• DOLENTIA MR can cause drowsiness or dizziness. Avoid driving, operating heavy machinery, or performing any tasks that require alertness until you know how this medication affects you. If you experience significant drowsiness, talk to your doctor about adjusting your dosage or switching to a different medication.
• Inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Certain medications can interact with DOLENTIA MR, potentially leading to adverse effects or reducing its effectiveness. Pay special attention to other pain relievers, muscle relaxants, or medications that cause drowsiness.
• If you have a history of liver or kidney problems, or stomach ulcers, discuss this with your doctor before taking DOLENTIA MR. These conditions may increase your risk of side effects, and your doctor may need to adjust your dosage or monitor you more closely while you are taking this medication. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• DOLENTIA MR is intended for short-term use. If your pain persists for more than a few days, or if it worsens despite taking the medication, consult your doctor. Long-term use of pain relievers can lead to various health problems, including stomach ulcers, kidney damage, and dependence. Your doctor can evaluate your condition and recommend alternative treatments if necessary.

• DOLENTIA MR 50/8MG TABLET 10'S can be taken with or without food. However, if you experience stomach upset, it is advisable to take it with food or after meals to minimize gastrointestinal discomfort. There are no specific food restrictions while taking this medication, but it is generally recommended to avoid excessive alcohol consumption as it may increase the risk of side effects.