DOXINATE TABLET 30'S
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DOXINATE TABLET 30'S

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DOXINATE TABLET 30'S

By MANEESH PHARMACEUTICALS LTD

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304.9

₹259.16

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About DOXINATE TABLET 30'S

  • Doxinate Tablet is a trusted and widely used medication specifically formulated to provide relief from nausea and vomiting, particularly during pregnancy. It combines the synergistic action of two active ingredients: Doxylamine succinate and Pyridoxine hydrochloride (Vitamin B6). Doxylamine succinate is an antihistamine that helps to reduce nausea and vomiting sensations, while Pyridoxine hydrochloride is a form of Vitamin B6, known for its antiemetic properties and its role in reducing nausea.
  • This medication is a reliable choice for pregnant women experiencing morning sickness, a common condition characterized by nausea and vomiting. Doxinate helps to alleviate these symptoms, improving the quality of life for expectant mothers. The combination of doxylamine and pyridoxine works by addressing different pathways involved in the nausea and vomiting reflex.
  • Doxylamine blocks histamine receptors in the brain, which are responsible for triggering nausea. Pyridoxine, on the other hand, is believed to help by restoring certain vitamin deficiencies which may be causing the nausea. Together, they provide a comprehensive approach to managing nausea and vomiting. Doxinate is generally well-tolerated. However, as with any medication, it's essential to consult with a healthcare professional before use, especially during pregnancy, to ensure it is appropriate for your individual needs and to rule out any potential interactions with other medications or pre-existing conditions.
  • The recommended dosage and duration of treatment will be determined by your doctor based on the severity of your symptoms. Follow the prescribed instructions carefully. If you experience any persistent or concerning side effects, such as drowsiness, dry mouth, or blurred vision, inform your doctor promptly. Doxinate offers a safe and effective solution for managing nausea and vomiting, helping you to enjoy a more comfortable and healthy pregnancy.

Uses of DOXINATE TABLET 30'S

  • Treatment of nausea and vomiting during pregnancy.
  • Management of morning sickness.
  • Treatment of Hyperemesis Gravidarum (severe nausea and vomiting in pregnancy).
  • Reducing vomiting associated with pregnancy.
  • Relieving discomfort caused by pregnancy-related nausea.

How DOXINATE TABLET 30'S Works

  • DOXINATE TABLET 30'S is a combination medicine primarily used to treat nausea and vomiting during pregnancy. It combines the actions of two active ingredients: Doxylamine succinate and Pyridoxine hydrochloride (Vitamin B6). Understanding how each component works helps to appreciate the overall effect of the medication.
  • Doxylamine succinate is an antihistamine. It works by blocking the effects of histamine, a natural substance in the body that can cause nausea and vomiting. Specifically, doxylamine blocks H1 histamine receptors in the brain. By blocking these receptors, doxylamine reduces the signals that trigger the vomiting center in the brain, thereby alleviating nausea and vomiting sensations. Its sedative properties can also contribute to its antiemetic effect, providing relief and promoting rest.
  • Pyridoxine hydrochloride, also known as Vitamin B6, is a water-soluble vitamin that plays a vital role in various metabolic processes in the body. During pregnancy, hormonal changes can disrupt the balance of neurotransmitters, potentially leading to nausea and vomiting. Vitamin B6 helps to restore this balance by participating in the synthesis of neurotransmitters like serotonin, dopamine, and norepinephrine. These neurotransmitters are crucial for regulating mood, appetite, and the vomiting reflex. By ensuring optimal levels of these neurotransmitters, pyridoxine can effectively reduce nausea and vomiting.
  • The synergistic action of doxylamine and pyridoxine makes DOXINATE TABLET 30'S an effective treatment for morning sickness. Doxylamine addresses the histamine-mediated nausea, while pyridoxine helps correct underlying neurotransmitter imbalances. Together, they provide comprehensive relief from pregnancy-related nausea and vomiting, improving the quality of life for expectant mothers. It's important to take DOXINATE TABLET 30'S as prescribed by your doctor to ensure its safety and effectiveness.
  • In summary, Doxinate works by utilizing an antihistamine to block signals that trigger the vomiting center in the brain while simultaneously employing Vitamin B6 to balance neurotransmitters, working in conjunction to provide comprehensive relief from nausea and vomiting commonly experienced during pregnancy. This dual-action approach targets different pathways involved in causing these symptoms.

Side Effects of DOXINATE TABLET 30'SArrow

Doxinate Tablet may cause several side effects, although not everyone experiences them. Common side effects include drowsiness, dry mouth, constipation, blurred vision, dizziness, and difficulty concentrating. Less common side effects can include headache, nausea, vomiting, diarrhea, epigastric pain, increased appetite, insomnia, nervousness, confusion, tremor, irritability, palpitations, skin rash, and urinary retention. In rare cases, severe allergic reactions may occur. If you experience any concerning side effects, discontinue use and consult your doctor immediately. This is not an exhaustive list, and other side effects may occur. Inform your doctor if you experience any unusual symptoms while taking Doxinate.

Safety Advice for DOXINATE TABLET 30'SArrow

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Allergies

Allergies

Allergies: Do not use Doxinate Tablet 30'S if you are allergic to it.

Dosage of DOXINATE TABLET 30'SArrow

  • The recommended dosage of DOXINATE TABLET 30'S can vary based on individual needs and the severity of nausea and vomiting during pregnancy. Typically, the initial dose is two tablets taken at bedtime. This timing is strategic, as it allows the medication to be most effective in controlling morning sickness symptoms when they are often at their peak. If this dosage adequately controls symptoms, it should be continued.
  • In cases where the initial dose is insufficient to manage nausea and vomiting, your physician may recommend increasing the dosage. This could involve taking one tablet in the morning and two tablets at bedtime, or even one tablet in the morning, one in the afternoon, and two at bedtime. It is crucial to strictly adhere to your doctor's instructions regarding dosage adjustments. Do not increase the dose on your own, as this could lead to unwanted side effects.
  • The maximum recommended daily dose of DOXINATE TABLET 30'S is four tablets. Exceeding this dosage is not advised, as it does not necessarily provide better symptom control and may increase the risk of adverse reactions. If you find that four tablets a day are not effectively managing your symptoms, it is important to consult your doctor to explore alternative treatment options.
  • It's also important to note that DOXINATE TABLET 30'S should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets, as this could affect the way the medication is released and absorbed in your body. Consistency in taking the medication at the same times each day can also help to maintain stable blood levels and optimize its effectiveness. Take 'DOXINATE TABLET 30'S' only as per the prescription by your physician only.

What if I miss my dose of DOXINATE TABLET 30'S?Arrow

  • If you miss a dose of DOXINATE TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store DOXINATE TABLET 30'S?Arrow

  • Keep DOXINATE TAB 1X30 away from the reach of children and pets.
  • Store DOXINATE TAB 1X30 at room temperature.

Benefits of DOXINATE TABLET 30'SArrow

  • Doxinate Tablet is a widely prescribed medication primarily used to alleviate nausea and vomiting, particularly during pregnancy. It combines doxylamine, an antihistamine, and pyridoxine (vitamin B6), offering a dual-action approach to combat morning sickness and related discomfort.
  • The primary benefit of Doxinate Tablet is its effectiveness in reducing nausea and vomiting, especially in pregnant women experiencing morning sickness. Morning sickness, characterized by nausea and vomiting, can significantly impact a woman's quality of life during pregnancy. Doxinate helps to alleviate these symptoms, allowing pregnant women to maintain a better appetite, stay hydrated, and experience greater overall well-being.
  • Doxylamine, an antihistamine component of Doxinate, works by blocking the effects of histamine, a natural substance in the body that can cause nausea and vomiting. By blocking histamine, doxylamine helps to reduce the sensation of nausea and the urge to vomit. Pyridoxine (vitamin B6), the other active ingredient, is a water-soluble vitamin that plays a crucial role in various bodily functions, including neurotransmitter synthesis. It is believed that pyridoxine helps to alleviate nausea by influencing neurotransmitter activity in the brain.
  • Doxinate Tablet is considered safe for use during pregnancy when taken as directed by a healthcare professional. It has a long history of use in managing morning sickness and is often recommended as a first-line treatment option. The combination of doxylamine and pyridoxine offers a synergistic effect, providing greater relief from nausea and vomiting compared to either ingredient used alone.
  • Beyond pregnancy-related nausea, Doxinate can also be prescribed to manage nausea and vomiting associated with other conditions, such as motion sickness or certain gastrointestinal disorders. Its ability to reduce the sensation of nausea makes it a versatile medication for various situations. By effectively controlling nausea and vomiting, Doxinate helps to prevent dehydration, electrolyte imbalances, and malnutrition, which can be particularly important for pregnant women and individuals with underlying medical conditions.
  • Doxinate is available in tablet form and is typically taken orally. The dosage and frequency of administration will vary depending on the individual's condition and the severity of symptoms. It is essential to follow the healthcare provider's instructions carefully and not exceed the recommended dose. Doxinate is generally well-tolerated, but some individuals may experience side effects such as drowsiness, dry mouth, or constipation. These side effects are usually mild and temporary.
  • In summary, Doxinate Tablet offers a valuable solution for managing nausea and vomiting, particularly during pregnancy. Its dual-action formula, combining doxylamine and pyridoxine, effectively reduces nausea and improves overall well-being. When used under the guidance of a healthcare professional, Doxinate can provide significant relief and help individuals maintain a better quality of life despite experiencing nausea and vomiting.

How to use DOXINATE TABLET 30'SArrow

  • Always take DOXINATE TABLET 30'S exactly as your doctor has told you. This medicine is usually taken orally. The standard dosage is typically one or two tablets daily. Your doctor may adjust the dose based on your individual needs and how well the medication works for you. It’s best to swallow the tablets whole with a glass of water. Do not crush, chew, or break the tablets unless specifically instructed by your healthcare provider, as this could affect how the medication is released and absorbed by your body.
  • For optimal results, take DOXINATE TABLET 30'S at the same time each day. Many doctors recommend taking it in the evening, as this can help minimize morning sickness symptoms. If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It is important to maintain consistency with your treatment schedule for the best outcome. If you experience any troublesome side effects while taking DOXINATE TABLET 30'S, such as drowsiness, dry mouth, or constipation, inform your doctor. They can provide advice on managing these side effects. It's crucial to follow your doctor's instructions and attend all scheduled follow-up appointments to monitor your progress and ensure the medication is working effectively for you. Store the tablets in a cool, dry place away from direct sunlight and moisture.

Quick Tips for DOXINATE TABLET 30'SArrow

  • **Timing is Key:** Take Doxinate tablets at the same time each day, preferably before bedtime, to manage nausea and vomiting effectively. This consistent timing helps maintain a steady level of the medication in your system, maximizing its benefits throughout the day, especially during periods when nausea is most likely to occur.
  • **Hydration is Essential:** Combat dehydration, a common side effect of nausea and vomiting, by drinking plenty of fluids like water, clear broths, or electrolyte solutions. Staying hydrated not only alleviates discomfort but also helps maintain your overall health and well-being during pregnancy. Avoid sugary drinks, which can sometimes worsen nausea.
  • **Dietary Adjustments:** Opt for smaller, more frequent meals instead of large ones. Bland foods like toast, crackers, and bananas are easier to digest and less likely to trigger nausea. Identify and avoid any specific food triggers that exacerbate your symptoms. These adjustments can significantly reduce the severity of morning sickness.
  • **Consult Your Doctor:** If symptoms persist or worsen despite taking Doxinate, promptly consult your healthcare provider. They can assess your condition, adjust the dosage, or recommend alternative treatments. Self-treating without medical supervision can be risky, so professional guidance is crucial for optimal management of morning sickness.
  • **Lifestyle Modifications:** Get adequate rest and avoid strong odors or environments that trigger nausea. Fresh air and gentle activities can also help alleviate symptoms. Simple lifestyle changes, such as avoiding tight clothing and stressful situations, can contribute to a more comfortable pregnancy experience. Consider using acupressure bands designed to reduce nausea.

Food Interactions with DOXINATE TABLET 30'SArrow

  • While taking DOXINATE TABLET 30'S, be mindful of potential interactions with food and beverages. Although specific food interactions may not be extensively documented, it is generally advisable to avoid consuming large meals immediately before or after taking this medication.
  • High-fat meals may delay the absorption of the medication, potentially reducing its effectiveness. It is also recommended to avoid alcohol consumption while taking DOXINATE TABLET 30'S, as it can exacerbate drowsiness and dizziness, common side effects of the drug.
  • Maintain a consistent dietary pattern during the course of the medication, and consult your doctor or pharmacist if you have any concerns about specific food items or beverages.

FAQs

What is Doxinate Tablet used for?Arrow

Doxinate Tablet is commonly used to treat nausea and vomiting during pregnancy.

What are the main ingredients in Doxinate Tablet?Arrow

Doxinate Tablet contains Doxylamine Succinate and Pyridoxine Hydrochloride (Vitamin B6).

What are the common side effects of Doxinate Tablet?Arrow

Common side effects of Doxinate Tablet include drowsiness, dizziness, dry mouth, and constipation.

Can I take Doxinate Tablet with or without food?Arrow

Doxinate Tablet can be taken with or without food, but it is better to take it at the same time each day.

What is the proper way to store Doxinate Tablet?Arrow

Doxinate Tablet should be stored at room temperature, away from direct sunlight and moisture.

Is Doxinate Tablet safe for pregnancy?Arrow

Doxinate Tablet is considered safe for use in pregnancy, but it is important to consult a doctor before taking it.

Does Doxinate Tablet cause drowsiness? If so, what should I do?Arrow

Yes, Doxinate Tablet can cause drowsiness. If this occurs, avoid driving or operating machinery.

Can an overdose of Doxinate Tablet be dangerous?Arrow

Yes, an overdose of Doxinate Tablet can be dangerous and requires immediate medical attention.

Does Doxinate Tablet interact with other medications?Arrow

Doxinate Tablet can interact with certain medications, so it is important to tell your doctor about all the medications you are taking.

Can I take Doxinate Tablet while breastfeeding?Arrow

It is important to consult a doctor before taking Doxinate Tablet while breastfeeding.

How long does it take for Doxinate Tablet to start working?Arrow

Doxinate Tablet usually takes 1-2 hours to start working.

What should I do if I miss a dose of Doxinate Tablet?Arrow

If you miss a dose of Doxinate Tablet, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can Doxinate Tablet be taken on an empty stomach?Arrow

Doxinate Tablet can be taken on an empty stomach, but some people may experience stomach upset. Taking it with food may reduce the chance of stomach upset.

Is Doxinate Tablet habit-forming?Arrow

No, Doxinate Tablet is not habit-forming.

What is the price of Doxinate Tablet?Arrow

The price of Doxinate Tablet can vary depending on the brand, quantity, and pharmacy.

References

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DailyMed - DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE delayed release tablet, for oral use

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Safety and efficacy of delayed-release doxylamine and pyridoxine for nausea and vomiting of pregnancy: a randomized placebo-controlled trial.

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Evaluation of efficacy and safety of delayed-release doxylamine and pyridoxine combination for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial.

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Doxylamine: An overview of its pharmacology, uses, and safety.

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Doxylamine succinate-pyridoxine hydrochloride for nausea and vomiting of pregnancy: prescribing considerations

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Reviewed on 29-01-2024

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MANEESH PHARMACEUTICALS LTD

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₹259.16

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