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Content Reviewed By:
Dr. Rajesh Sharma
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
While Drep Ear Drops are generally well-tolerated, some individuals may experience side effects. These can include: * **Common Side Effects:** * Mild burning or stinging sensation in the ear * Temporary itching * Redness or irritation of the ear canal * **Uncommon Side Effects:** * Allergic reactions (rash, hives, swelling, difficulty breathing - seek immediate medical attention) * Ear pain * Increased ear discharge * Dizziness * Headache * **Rare Side Effects:** * Hearing loss (very rare) * Tinnitus (ringing in the ears) * Superinfection (new infection) with prolonged use.

General precautions and misuse
Use only as prescribedDrep Ear Drops is intended solely for otic (ear) use and must not be used in the eyes, nose, mouth, or on large areas of skin.
DREP Ear Drops 5ml is a medication used to treat conditions like ear infections and inflammation. It also helps relieve ear pain and itching.
DREP Ear Drops 5ml typically contains antibiotics (such as Ofloxacin) and anti-inflammatory medications (such as Beclometasone).
Follow the instructions given by your doctor. Typically, you will need to lie down with the affected ear facing upwards, instill the drops, and remain in that position for a few minutes to allow the medication to penetrate.
Common side effects of DREP Ear Drops 5ml may include ear irritation, itching, or mild burning. Consult a doctor if side effects persist or become severe.
DREP Ear Drops 5ml should only be used in children under the advice of a doctor. The dosage and duration of use should be determined by the doctor.
Consult your doctor or pharmacist before using DREP Ear Drops 5ml with other medications to avoid any potential drug interactions.
Store DREP Ear Drops 5ml at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.
If you miss a dose of DREP Ear Drops 5ml, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
DREP Ear Drops 5ml can help relieve ear pain, but it may take some time for immediate relief. Consult a doctor if the pain persists.
DREP Ear Drops 5ml is not typically designed to remove earwax. Consult your doctor for earwax removal.
If DREP Ear Drops 5ml is accidentally swallowed, seek immediate medical attention or call a poison control center.
No, DREP Ear Drops 5ml should always be kept in a closed bottle to avoid contamination.
The use of DREP Ear Drops 5ml is unlikely to affect hearing ability, but consult a doctor if you notice any changes in hearing.
Once opened, a bottle of DREP Ear Drops 5ml can typically be used for up to 28 days. Do not use it after the expiration date.
DREP Ear Drops 5ml contains Ofloxacin, but other brands may have additional ingredients or different concentrations. Always use the brand prescribed by your doctor.
Drep Ear Drops is generally used for inflammatory conditions of the external ear canal where mixed bacterial and fungal infection is suspected or confirmed, and where pain, itching, and swelling are present. The combination of beclometasone, clotrimazole, lignocaine, and neomycin provides anti‑inflammatory, antifungal, antibacterial, and local anaesthetic effects. It is not intended for routine use in uncomplicated earwax or purely viral conditions unless specifically advised by a doctor.
The exact number of drops and frequency of use must be determined by a doctor and the product leaflet, and should not be improvised. In general, ear drops are applied by tilting the head so the affected ear faces upward, instilling the prescribed number of drops into the ear canal, and keeping the head tilted for several minutes to allow the solution to reach the affected area. The dropper tip should not touch the ear or any surface to avoid contamination. After use, the cap should be replaced tightly. Do not use more often or for longer than recommended by your prescriber.
Drep Ear Drops should not be used in the presence of a known or suspected perforated eardrum, or in patients with tympanostomy tubes, unless specifically prescribed by an ear specialist. The neomycin component, and potentially other ingredients, may reach the middle or inner ear and increase the risk of ototoxicity, which can affect hearing or balance. If you have ear discharge, a history of eardrum perforation, or ear surgery, you must inform your doctor before using this medicine.
Most people tolerate Drep Ear Drops well when used for a short period as directed. Possible side effects include mild transient burning, stinging, or irritation at the application site, itching, or a feeling of fullness in the ear. Less commonly, allergic or sensitisation reactions may occur, especially to neomycin or local anaesthetics, presenting as increased redness, swelling, rash, or worsening itching. Prolonged or repeated use of topical corticosteroids in the ear may lead to skin thinning, delayed healing, or overgrowth of non‑susceptible organisms. If you notice worsening pain, hearing changes, severe rash, or dizziness, stop using the drops and seek medical advice promptly.
Use of Drep Ear Drops in children should be strictly under medical supervision. The safety and appropriate duration of therapy depend on the child’s age, the underlying diagnosis, and the condition of the eardrum. Paediatric ears are more vulnerable to damage from inappropriate topical therapy, particularly if the eardrum is not intact. A doctor, preferably with experience in paediatric ear conditions, should examine the ear and decide whether this combination is suitable and for how long it should be used.
Data on the use of this exact combination in pregnancy are limited. Systemic absorption from the external ear canal is expected to be low when the eardrum is intact and the product is used for a short duration. However, because it contains a corticosteroid, an aminoglycoside antibiotic, and a local anaesthetic, it should be used during pregnancy only if the potential benefit justifies any potential risk to the fetus. Pregnant patients should consult their doctor before starting therapy, and self‑medication is not recommended.
When Drep Ear Drops is used in the external ear with an intact eardrum, systemic absorption of its components is expected to be minimal, and significant transfer into breast milk is unlikely. Nevertheless, formal data for this specific combination in breastfeeding are limited. A breastfeeding mother should use it only on medical advice, for the shortest effective duration, and should monitor for any unexpected reactions in herself. The drops must not be applied to the breast or nipple area.
Because Drep Ear Drops is applied topically to the ear, clinically significant systemic drug interactions are unlikely when the eardrum is intact and the product is used for a short period. However, if there is a perforated eardrum or prolonged use, systemic absorption of neomycin and beclometasone could theoretically occur. Patients receiving other ototoxic medicines, such as systemic aminoglycosides, or those on long‑term corticosteroid therapy should inform their doctor. Always provide your full medication list, including over‑the‑counter products and herbal supplements, to your healthcare provider.
If you miss a scheduled application, use the drops as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and resume your regular schedule. Do not double the amount to make up for a missed dose, as this may increase the risk of local irritation or other adverse effects without improving efficacy. If you frequently forget doses, discuss this with your doctor, as adherence is important for successful treatment.
The duration of therapy must be determined by your doctor based on the cause and severity of your ear condition and your response to treatment. Combination preparations containing corticosteroids and antibiotics are generally intended for short‑term use. Prolonged or repeated courses without medical review can increase the risk of local adverse effects, sensitisation to neomycin, and overgrowth of resistant organisms or fungi. If symptoms do not improve within the timeframe advised by your doctor, or if they recur soon after stopping, you should be re‑examined rather than continuing treatment on your own.
Use Drep Ear Drops only in the ear and exactly as prescribed. Do not insert cotton buds or other objects deep into the ear canal while using the drops, as this may damage the skin or eardrum and worsen infection. Avoid water entering the affected ear during treatment, for example by using an ear plug or cotton wool coated with petroleum jelly during bathing if advised by your doctor. Do not share the bottle with anyone else to prevent cross‑infection. If the solution changes colour, becomes cloudy, or particles are visible, do not use it and consult a pharmacist or doctor.
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DWD PHARMACEUTICALS LIMITED
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India

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