DROLGAN TABLET 10'S

How DROLGAN TABLET 10'S Works

• DROLGAN TABLET 10'S is a combination medication designed to alleviate pain and inflammation. It contains two active ingredients: Drotaverine and Mefenamic Acid. These components work synergistically to provide relief from various types of pain, including abdominal cramps, muscle spasms, and menstrual pain.
• Drotaverine is an antispasmodic medication. It works by relaxing the smooth muscles in the body. Smooth muscles are found in the walls of internal organs such as the stomach, intestines, uterus, and bladder. When these muscles contract excessively, they can cause pain and discomfort. Drotaverine inhibits the enzyme phosphodiesterase IV (PDE IV). PDE IV is responsible for breaking down cyclic AMP (cAMP) in smooth muscle cells. By inhibiting PDE IV, Drotaverine increases cAMP levels within these cells. Elevated cAMP levels lead to the relaxation of smooth muscles, thereby reducing spasms and relieving pain associated with conditions like irritable bowel syndrome (IBS), biliary colic, and menstrual cramps. Unlike some other antispasmodics, Drotaverine has a selective action on smooth muscles, with minimal impact on the cardiovascular system.
• Mefenamic Acid is a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting the production of prostaglandins, which are hormone-like substances that contribute to inflammation, pain, and fever. Mefenamic Acid blocks the action of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are responsible for converting arachidonic acid into prostaglandins. By inhibiting COX enzymes, Mefenamic Acid reduces the synthesis of prostaglandins, thereby alleviating pain, inflammation, and fever. Mefenamic Acid is particularly effective in treating menstrual pain (dysmenorrhea) and other types of inflammatory pain. Its anti-inflammatory properties help to reduce swelling and tenderness in the affected area.
• The combined action of Drotaverine and Mefenamic Acid in DROLGAN TABLET 10'S provides comprehensive relief from pain and inflammation. Drotaverine relaxes smooth muscles to reduce spasms, while Mefenamic Acid inhibits prostaglandin synthesis to alleviate pain and inflammation. This dual mechanism of action makes DROLGAN TABLET 10'S effective in managing various painful conditions, providing patients with much-needed relief and improved quality of life. Always follow your doctor's instructions regarding dosage and usage.

Common side effects of DROLGAN TABLET may include nausea, vomiting, stomach upset, heartburn, diarrhea, constipation, drowsiness, dizziness, headache, blurred vision, dry mouth, and skin rash. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing), liver problems (yellowing of the skin or eyes, dark urine, persistent nausea/vomiting, unusual fatigue), kidney problems (change in the amount of urine), and gastrointestinal bleeding (black/tarry stools, persistent abdominal pain). This is not an exhaustive list, and other side effects may occur. Consult your doctor if you experience any unusual or bothersome symptoms.

• If you miss a dose of DROLGAN TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep DROLGAN TAB 1X10 away from the reach of children and pets.
• Store DROLGAN TAB 1X10 at room temperature.

• DROLGAN TABLET 10'S can be taken with or without food. However, if you experience stomach upset, taking it with food may help.
• Avoid consuming grapefruit or grapefruit juice while taking DROLGAN TABLET 10'S, as it may increase the drug's concentration in your body and potentially lead to increased side effects.
• There are no specific food restrictions while taking DROLGAN TABLET 10'S, but maintaining a balanced diet is always recommended for overall health.