DROTIN PLUS TABLET 10'S

How DROTIN PLUS TABLET 10'S Works

• DROTIN PLUS TABLET 10'S is a combination medication designed to alleviate abdominal pain and cramps, primarily associated with conditions like irritable bowel syndrome (IBS), dysmenorrhea (menstrual cramps), and other gastrointestinal disorders. It combines two active ingredients: Drotaverine and Mefenamic Acid, each contributing uniquely to its pain-relieving action.
• Drotaverine is an antispasmodic medication that works by directly relaxing the smooth muscles in the abdomen. Smooth muscles are responsible for involuntary contractions in the digestive tract. In conditions like IBS or dysmenorrhea, these muscles can contract excessively, leading to pain and discomfort. Drotaverine inhibits the enzyme phosphodiesterase IV (PDE IV), which is involved in muscle contraction. By inhibiting PDE IV, Drotaverine reduces the availability of calcium within the muscle cells, leading to muscle relaxation and a reduction in spasms and pain.
• Mefenamic Acid is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins. Prostaglandins are hormone-like substances that contribute to inflammation, pain, and fever. In conditions like menstrual cramps, the uterus produces high levels of prostaglandins, leading to painful contractions. Mefenamic Acid blocks the cyclooxygenase (COX) enzymes, COX-1 and COX-2, which are responsible for synthesizing prostaglandins. By reducing prostaglandin production, Mefenamic Acid reduces inflammation and pain.
• The combined action of Drotaverine and Mefenamic Acid provides comprehensive relief from abdominal pain and cramps. Drotaverine directly relaxes the smooth muscles, reducing spasms, while Mefenamic Acid reduces inflammation and pain by inhibiting prostaglandin production. This dual mechanism of action makes DROTIN PLUS TABLET 10'S effective in managing conditions characterized by abdominal pain and cramps.

Common side effects of Drotin Plus Tablet may include nausea, vomiting, heartburn, stomach pain, loss of appetite, dry mouth, dizziness, sleepiness, weakness, and skin rash. Less common but potentially serious side effects can include allergic reactions (such as swelling of the face, lips, or tongue, difficulty breathing), liver problems (such as jaundice, dark urine, persistent fatigue), and kidney problems (such as changes in urine output). Consult your doctor if you experience any persistent or severe side effects.

• If you miss a dose of Drotin Plus Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep DROTIN PLUS TAB 1X10 away from the reach of children and pets.
• Store DROTIN PLUS TAB 1X10 at room temperature.

• Take DROTIN PLUS TABLET 10'S as prescribed by your doctor to relieve abdominal pain and cramps. It works by relaxing the muscles in your stomach and gut.
• For optimal results, take DROTIN PLUS TABLET 10'S at a fixed time each day, with or without food. If you experience stomach upset, try taking it with food to minimize discomfort.
• Inform your doctor about all other medications, including over-the-counter medicines and herbal supplements, that you are currently taking before starting DROTIN PLUS TABLET 10'S to avoid potential drug interactions.
• If you experience any persistent or worsening side effects such as nausea, vomiting, or allergic reactions, consult your doctor immediately. Do not exceed the recommended dosage without medical advice.
• Avoid alcohol consumption while taking DROTIN PLUS TABLET 10'S, as it may increase the risk of side effects such as dizziness and drowsiness. If you are pregnant, planning to conceive, or breastfeeding, consult your doctor before using this medicine.

• DROTIN PLUS TABLET 10'S can be taken with or without food. However, if you experience stomach upset, it is advisable to take it with food or after meals.
• Avoid taking this medicine with grapefruit or grapefruit juice, as it may increase the risk of side effects.