DUOVA INHALER 200 MD

How DUOVA INHALER 200 MD Works

• DUOVA Inhaler 200 MD is a combination medication containing two active ingredients: ipratropium bromide and levosalbutamol. These components work synergistically to provide relief from the symptoms of chronic obstructive pulmonary disease (COPD), such as wheezing, shortness of breath, coughing, and chest tightness. Ipratropium bromide is an anticholinergic bronchodilator, while levosalbutamol is a short-acting beta2-agonist (SABA).
• Ipratropium bromide works by blocking the action of acetylcholine, a neurotransmitter that causes the muscles around the airways to tighten. By blocking acetylcholine, ipratropium bromide helps to relax these muscles, widening the airways and making it easier to breathe. This mechanism primarily targets the cholinergic pathways in the lungs, which are often overactive in COPD patients, contributing to bronchoconstriction and mucus production.
• Levosalbutamol, on the other hand, works by stimulating beta2-adrenergic receptors in the lungs. When levosalbutamol binds to these receptors, it triggers a cascade of intracellular events that lead to the relaxation of bronchial smooth muscle. This bronchodilation effect helps to open up the airways, allowing for improved airflow and reduced breathing difficulty. Levosalbutamol is particularly effective in providing quick relief during acute COPD exacerbations.
• The combined action of ipratropium bromide and levosalbutamol offers a dual approach to bronchodilation. Ipratropium bromide provides a longer-lasting effect by targeting the cholinergic pathways, while levosalbutamol offers rapid relief through beta2-adrenergic stimulation. This combination can lead to a more sustained and effective bronchodilation compared to using either medication alone. The overlapping yet distinct mechanisms of action make DUOVA Inhaler 200 MD a valuable tool in managing COPD symptoms and improving overall respiratory function.
• DUOVA Inhaler 200 MD is used to prevent bronchospasm (wheezing, shortness of breath) in people with reversible obstructive airway disease. It widens the air passages in the lungs, which makes it easier to breathe. It should be used regularly to help keep your airways open. Once opened, it relieves shortness of breath, wheezing, and coughing and helps you perform your daily activities more easily.

Common side effects of Duova Inhaler may include: Cough, Dryness in mouth, Headache, Hoarseness of voice, Increased heart rate, Muscle cramp, Nausea, Sore throat, Tremor. Less common or rare side effects may include: Allergic reactions (rash, itching, swelling), Angina, Anxiety, Blurred vision, Bronchospasm, Dizziness, Eye pain, High blood pressure, Hypokalemia (low potassium), Insomnia, Irregular heartbeat, Nervousness, Paradoxical bronchospasm (sudden wheezing immediately after using the inhaler), Pneumonia, Throat irritation, Urinary retention, Voice changes, Vomiting, Weakness.

• If you miss a dose of DUOVA INHALER 200 MD, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep DUOVA INHALER 200MD away from the reach of children and pets.
• Store DUOVA INHALER 200MD in a refrigerator (2 - 8°C). Do not freeze.

• Always use DUOVA INHALER 200 MD exactly as your doctor has prescribed. Do not alter the dosage or frequency without consulting your healthcare provider, as incorrect usage can reduce its effectiveness and increase the risk of side effects. Read and understand the patient information leaflet provided with the inhaler before your first use, and ask your doctor or pharmacist if anything is unclear.
• Prime the inhaler before the first use or if it hasn't been used for more than a week. To prime, remove the cap and shake the inhaler well. Then, point the inhaler away from you and press the canister to release a test spray. Repeat this process until you see a spray, usually requiring 2-3 actuations. This ensures the inhaler delivers the correct dose.
• To administer a dose, exhale completely, then place the mouthpiece of the inhaler into your mouth, creating a tight seal with your lips. As you start to inhale slowly and deeply through your mouth, press down firmly on the canister to release the medication. Continue inhaling deeply, then remove the inhaler from your mouth and hold your breath for as long as comfortable, ideally for about 10 seconds. This allows the medication to reach deep into your lungs.
• After each use, rinse your mouth thoroughly with water and spit it out. This helps to prevent oral thrush (a fungal infection in the mouth) and reduces the amount of medication that is swallowed. Do not swallow the water. Regular rinsing is an important step in minimizing potential side effects.
• Clean your DUOVA INHALER 200 MD regularly, at least once a week, to prevent the buildup of medication and ensure proper function. Remove the canister and rinse the plastic actuator with warm water. Allow the actuator to air dry completely before reassembling the inhaler. Never immerse the canister in water. A clean inhaler delivers the correct dose more effectively.

• DUOVA INHALER 200 MD is generally safe to use with food. There are no known significant interactions between this medication and specific foods or beverages. You can use the inhaler as prescribed by your doctor without regard to meals.