DURANZO 50/50MG TABLET 10'S

How DURANZO 50/50MG TABLET 10'S Works

• DURANZO 50/50MG TABLET 10'S is a combination medication designed to manage premature ejaculation and erectile dysfunction in men. It contains two active ingredients: tramadol and sildenafil. Each component addresses a specific aspect of sexual function, working synergistically to improve overall sexual performance and satisfaction.
• Sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, primarily tackles erectile dysfunction. When a man is sexually stimulated, his body releases nitric oxide, which triggers the production of cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscles in the penis, allowing blood to flow in and create an erection. However, PDE5 enzymes break down cGMP, hindering the process. Sildenafil inhibits PDE5, preventing the breakdown of cGMP. As a result, the smooth muscles in the penis relax more effectively, promoting increased blood flow and facilitating a firmer and more sustained erection. The effects of sildenafil are dependent on sexual stimulation; it doesn't create an erection on its own but enhances the body's natural response to arousal.
• Tramadol, on the other hand, addresses premature ejaculation. It's a centrally acting analgesic with weak opioid agonist activity and also inhibits the reuptake of serotonin and norepinephrine. The exact mechanism by which tramadol delays ejaculation isn't fully understood, but it's believed to involve several factors. Serotonin and norepinephrine are neurotransmitters that play a crucial role in regulating mood, pain, and ejaculation. By inhibiting their reuptake, tramadol increases the levels of these neurotransmitters in the synaptic cleft, the space between nerve cells. This, in turn, affects the ejaculatory reflex, increasing the time it takes to reach ejaculation.
• The combined effect of sildenafil and tramadol in DURANZO offers a dual benefit. Sildenafil improves erectile function, ensuring a satisfactory erection, while tramadol helps to delay ejaculation, prolonging the duration of sexual activity. This combination can lead to increased confidence, reduced anxiety, and improved sexual satisfaction for both the individual and their partner.
• It is crucial to remember that DURANZO should be taken under the guidance of a healthcare professional. They will assess your individual needs, medical history, and any potential drug interactions to determine if this medication is appropriate for you. Adhering to their prescribed dosage and instructions is paramount to maximizing benefits and minimizing potential side effects. Self-medication is strongly discouraged.

Common side effects of DURANZO 50/50MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, indigestion, loss of appetite, headache, dizziness, drowsiness, fatigue, weakness, dry mouth, blurred vision, increased sweating, and skin rash or itching. Less common side effects could involve anxiety, confusion, insomnia, tremors, changes in heart rate or blood pressure, difficulty breathing, jaundice (yellowing of skin or eyes), dark urine, pale stools, unusual bleeding or bruising, muscle pain or weakness, and allergic reactions such as hives, swelling, or difficulty breathing.

• If you miss a dose of DURANZO 50/50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep DURANZO 50/50MG TAB 1X10 away from the reach of children and pets.
• Store DURANZO 50/50MG TAB 1X10 at room temperature.

• Take DURANZO 50/50MG TABLET 10'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. Consistent timing is key, so take it at the same time each day to maintain a steady level of medication in your body. This helps ensure it works effectively.
• DURANZO 50/50MG TABLET 10'S can be taken with or without food, but consistency is important. If you experience stomach upset, taking it with food may help. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medication, as it can interact and potentially increase the risk of side effects. Talk to your doctor or pharmacist if you have any concerns about dietary interactions.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting DURANZO 50/50MG TABLET 10'S. This is crucial to avoid potential drug interactions. Pay special attention to blood thinners, heart medications, and other drugs that affect blood pressure. Keep an updated list of your medications and bring it with you to all doctor's appointments.
• Be aware of potential side effects, which may include dizziness, lightheadedness, headache, or nausea. If you experience any persistent or bothersome side effects, contact your doctor immediately. Avoid driving or operating heavy machinery until you know how DURANZO 50/50MG TABLET 10'S affects you. Report any serious side effects, such as chest pain, shortness of breath, or severe allergic reactions, to your doctor right away.
• Store DURANZO 50/50MG TABLET 10'S at room temperature, away from direct sunlight, heat, and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom. Properly dispose of any unused medication; do not flush it down the toilet or throw it in the trash. Check with your pharmacist for proper disposal methods in your area.

• DURANZO 50/50MG TABLET 10'S can be taken with or without food, but it is best to take it at a fixed time. Avoid consuming high-fat meals before taking DURANZO as it can decrease the absorption of the medicine.