duranzo 50/50mg tablet 10's
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DURANZO 50/50MG TABLET 10'S

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DURANZO 50/50MG TABLET 10'S

By AJANTA PHARMA LIMITED

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180.46

₹153.39

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About DURANZO 50/50MG TABLET 10'S

  • Duranzo Tab is typically a branded prescription medicine used in gynecological and hormonal conditions, most commonly related to menstrual cycle regulation, abnormal uterine bleeding, or hormone-related symptoms. The exact composition can vary by manufacturer and country, so patients must always check the active ingredient on the pack and follow their doctor’s specific instructions. It is generally used under medical supervision, especially in women of reproductive age, and is not intended for self-medication. Duranzo Tab may act by influencing female sex hormones, stabilizing the endometrium (lining of the uterus), and helping to correct hormonal imbalances that cause irregular or heavy periods. Depending on its active ingredient, it may also be used as part of treatment plans for conditions such as dysfunctional uterine bleeding, premenstrual symptoms, or other hormone-related gynecological issues. Because hormonal medicines can interact with other drugs and underlying conditions, a detailed medical history is important before starting therapy. Common side effects associated with hormone-related tablets can include nausea, mild headache, breast tenderness, mood changes, spotting between periods, or changes in menstrual flow. Some women may experience weight changes, bloating, or mild fluid retention. Most side effects are mild and temporary, but any persistent or severe symptoms should be reported to a healthcare professional. Sudden severe headache, chest pain, shortness of breath, vision changes, or leg swelling require urgent medical attention, as they may indicate rare but serious complications such as blood clots. Duranzo Tab should only be used in the dose, frequency, and duration prescribed by a qualified doctor. Patients should not adjust the dose or stop the medicine abruptly without medical advice, as this may disturb the menstrual cycle or reduce treatment effectiveness. It is important to inform the doctor about any history of liver disease, kidney disease, blood clotting disorders, hormone-sensitive cancers, migraines, uncontrolled high blood pressure, or unexplained vaginal bleeding before starting the medicine. Because brand formulations differ, the patient information leaflet that comes with the specific Duranzo Tab product should be read carefully. It will provide details on the exact active ingredient, approved indications, possible side effects, and specific precautions. When in doubt, patients should consult their gynecologist or physician rather than relying on general information alone.

Uses of DURANZO 50/50MG TABLET 10'S

  • Premature ejaculation treatment
  • Erectile dysfunction treatment

How DURANZO 50/50MG TABLET 10'S Works

  • DURANZO 50/50MG TABLET 10'S is a combination medication designed to manage premature ejaculation and erectile dysfunction in men. It contains two active ingredients: tramadol and sildenafil. Each component addresses a specific aspect of sexual function, working synergistically to improve overall sexual performance and satisfaction.
  • Sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, primarily tackles erectile dysfunction. When a man is sexually stimulated, his body releases nitric oxide, which triggers the production of cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscles in the penis, allowing blood to flow in and create an erection. However, PDE5 enzymes break down cGMP, hindering the process. Sildenafil inhibits PDE5, preventing the breakdown of cGMP. As a result, the smooth muscles in the penis relax more effectively, promoting increased blood flow and facilitating a firmer and more sustained erection. The effects of sildenafil are dependent on sexual stimulation; it doesn't create an erection on its own but enhances the body's natural response to arousal.
  • Tramadol, on the other hand, addresses premature ejaculation. It's a centrally acting analgesic with weak opioid agonist activity and also inhibits the reuptake of serotonin and norepinephrine. The exact mechanism by which tramadol delays ejaculation isn't fully understood, but it's believed to involve several factors. Serotonin and norepinephrine are neurotransmitters that play a crucial role in regulating mood, pain, and ejaculation. By inhibiting their reuptake, tramadol increases the levels of these neurotransmitters in the synaptic cleft, the space between nerve cells. This, in turn, affects the ejaculatory reflex, increasing the time it takes to reach ejaculation.
  • The combined effect of sildenafil and tramadol in DURANZO offers a dual benefit. Sildenafil improves erectile function, ensuring a satisfactory erection, while tramadol helps to delay ejaculation, prolonging the duration of sexual activity. This combination can lead to increased confidence, reduced anxiety, and improved sexual satisfaction for both the individual and their partner.
  • It is crucial to remember that DURANZO should be taken under the guidance of a healthcare professional. They will assess your individual needs, medical history, and any potential drug interactions to determine if this medication is appropriate for you. Adhering to their prescribed dosage and instructions is paramount to maximizing benefits and minimizing potential side effects. Self-medication is strongly discouraged.

Side Effects of DURANZO 50/50MG TABLET 10'SArrow

Common side effects of DURANZO 50/50MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, indigestion, loss of appetite, headache, dizziness, drowsiness, fatigue, weakness, dry mouth, blurred vision, increased sweating, and skin rash or itching. Less common side effects could involve anxiety, confusion, insomnia, tremors, changes in heart rate or blood pressure, difficulty breathing, jaundice (yellowing of skin or eyes), dark urine, pale stools, unusual bleeding or bruising, muscle pain or weakness, and allergic reactions such as hives, swelling, or difficulty breathing.

Safety Advice for DURANZO 50/50MG TABLET 10'SArrow

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Allergies

Contraindicated in known allergy

Do not take Duranzo Tab if you are known to be allergic to its active ingredient or any of the excipients listed in the product leaflet.

Dosage of DURANZO 50/50MG TABLET 10'SArrow

  • The recommended dosage of DURANZO 50/50MG TABLET 10'S varies significantly depending on individual patient factors, including the severity of their condition, their response to treatment, and any other existing medical conditions or medications they may be taking. It is crucial to adhere strictly to the dosage prescribed by your physician. Self-adjusting the dosage can lead to either reduced effectiveness or an increased risk of adverse effects.
  • Typically, DURANZO 50/50MG TABLET 10'S is administered orally. Your doctor will determine the appropriate starting dose, which may be adjusted over time based on your individual needs and how well you tolerate the medication. The tablets should be swallowed whole with a glass of water, and it's generally recommended to take them at the same time each day to maintain a consistent level of medication in your system.
  • Do not crush, chew, or break the tablets unless specifically instructed to do so by your healthcare provider. Doing so could affect the way the medication is released and absorbed, potentially altering its effectiveness or increasing the risk of side effects. If you have difficulty swallowing tablets, discuss this with your doctor or pharmacist; they may be able to suggest alternative formulations or methods of administration.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Doubling the dose can significantly increase the risk of adverse effects.
  • It's imperative to maintain regular follow-up appointments with your doctor while taking DURANZO 50/50MG TABLET 10'S. These appointments allow your doctor to monitor your progress, assess the effectiveness of the medication, and make any necessary adjustments to your dosage. Furthermore, these visits provide an opportunity to discuss any side effects or concerns you may be experiencing.
  • Take 'DURANZO 50/50MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of DURANZO 50/50MG TABLET 10'S?Arrow

  • If you miss a dose of DURANZO 50/50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store DURANZO 50/50MG TABLET 10'S?Arrow

  • Keep DURANZO 50/50MG TAB 1X10 away from the reach of children and pets.
  • Store DURANZO 50/50MG TAB 1X10 at room temperature.

Benefits of DURANZO 50/50MG TABLET 10'SArrow

  • DURANZO 50/50MG Tablet is a combination medication primarily used to manage premature ejaculation (PE) in men. Its dual-action formula addresses both the psychological and physiological aspects of this condition, offering a comprehensive approach to improving sexual health and well-being. One of the primary benefits of DURANZO is its ability to significantly delay ejaculation. This allows men to have greater control over their sexual response, leading to longer and more satisfying sexual encounters for both themselves and their partners. By increasing the time to ejaculation, DURANZO can help reduce the anxiety and frustration associated with PE, fostering a more relaxed and enjoyable sexual experience.
  • Beyond just delaying ejaculation, DURANZO helps improve overall sexual satisfaction. The increased control and extended duration of intercourse can lead to a greater sense of fulfillment and pleasure for both partners. This can strengthen intimacy and improve the quality of the relationship. Men who use DURANZO often report feeling more confident and less stressed during sexual activity, further enhancing their satisfaction.
  • DURANZO addresses the psychological component of PE. The anxiety and stress related to premature ejaculation can be a significant burden for many men. By effectively managing the physical symptoms, DURANZO helps reduce this anxiety, allowing men to focus on enjoying the moment and connecting with their partner. This can lead to a significant improvement in their self-esteem and overall mental well-being.
  • The combined action of its active ingredients makes DURANZO a powerful tool in managing PE. One of the ingredients, works by increasing serotonin levels in the brain, which helps delay ejaculation. The other ingredient, functions to reduce anxiety, thus, addressing two key factors contributing to PE. This synergistic effect provides a more effective and comprehensive solution compared to single-ingredient treatments.
  • Many men experience improved confidence in their sexual abilities after using DURANZO. The ability to control ejaculation and prolong intercourse can boost self-esteem and reduce feelings of inadequacy. This newfound confidence can extend beyond the bedroom, positively impacting other areas of their lives.
  • DURANZO can lead to enhanced relationship satisfaction by improving communication and intimacy between partners. When men are able to address their PE issues, it opens up opportunities for more open and honest conversations about sex and intimacy. This can strengthen the bond between partners and lead to a more fulfilling relationship.
  • By managing premature ejaculation, DURANZO helps reduce the overall stress associated with sexual performance. This can lead to a more relaxed and enjoyable sexual experience, free from the pressure and anxiety of PE. This reduction in stress can also have positive effects on other aspects of life, such as work and social interactions.
  • DURANZO can be a valuable component of a broader approach to improving sexual health. When combined with lifestyle changes such as regular exercise, a healthy diet, and stress management techniques, DURANZO can help men achieve optimal sexual function and overall well-being.

How to use DURANZO 50/50MG TABLET 10'SArrow

  • DURANZO 50/50MG TABLET 10'S should be taken exactly as prescribed by your doctor. Do not alter the dosage or frequency of administration without consulting your healthcare provider. This medication is typically taken orally with a glass of water. It can be taken with or without food, but taking it at the same time each day will help you remember. Consistency is key to maximizing its effectiveness.
  • Before starting DURANZO 50/50MG TABLET 10'S, inform your doctor about any pre-existing medical conditions you have, especially heart problems, liver disease, kidney disease, or any mental health disorders. Also, disclose all other medications you are currently taking, including prescription drugs, over-the-counter medicines, and herbal supplements, to avoid potential drug interactions.
  • Swallow the tablet whole; do not crush, chew, or break it. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist for possible alternative formulations or techniques.
  • The duration of treatment with DURANZO 50/50MG TABLET 10'S will be determined by your doctor based on your specific condition and response to therapy. Do not stop taking the medication abruptly, as this may lead to withdrawal symptoms or a worsening of your condition. If you need to discontinue the medication, your doctor will gradually reduce the dosage.
  • If you miss a dose of DURANZO 50/50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Store DURANZO 50/50MG TABLET 10'S at room temperature, away from heat, light, and moisture. Keep it out of the reach of children and pets. Properly dispose of any unused medication or expired tablets.
  • Regular follow-up appointments with your doctor are essential while taking DURANZO 50/50MG TABLET 10'S. Your doctor will monitor your progress, assess your response to the medication, and make any necessary adjustments to your treatment plan. Be sure to report any side effects or unusual symptoms to your doctor promptly.
  • While taking DURANZO 50/50MG TABLET 10'S, avoid consuming alcohol, as it can increase the risk of side effects such as dizziness, drowsiness, and impaired coordination. It is also advisable to avoid driving or operating heavy machinery until you know how the medication affects you.

Quick Tips for DURANZO 50/50MG TABLET 10'SArrow

  • Take DURANZO 50/50MG TABLET 10'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. Consistent timing is key, so take it at the same time each day to maintain a steady level of medication in your body. This helps ensure it works effectively.
  • DURANZO 50/50MG TABLET 10'S can be taken with or without food, but consistency is important. If you experience stomach upset, taking it with food may help. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medication, as it can interact and potentially increase the risk of side effects. Talk to your doctor or pharmacist if you have any concerns about dietary interactions.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting DURANZO 50/50MG TABLET 10'S. This is crucial to avoid potential drug interactions. Pay special attention to blood thinners, heart medications, and other drugs that affect blood pressure. Keep an updated list of your medications and bring it with you to all doctor's appointments.
  • Be aware of potential side effects, which may include dizziness, lightheadedness, headache, or nausea. If you experience any persistent or bothersome side effects, contact your doctor immediately. Avoid driving or operating heavy machinery until you know how DURANZO 50/50MG TABLET 10'S affects you. Report any serious side effects, such as chest pain, shortness of breath, or severe allergic reactions, to your doctor right away.
  • Store DURANZO 50/50MG TABLET 10'S at room temperature, away from direct sunlight, heat, and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom. Properly dispose of any unused medication; do not flush it down the toilet or throw it in the trash. Check with your pharmacist for proper disposal methods in your area.

Food Interactions with DURANZO 50/50MG TABLET 10'SArrow

  • DURANZO 50/50MG TABLET 10'S can be taken with or without food, but it is best to take it at a fixed time. Avoid consuming high-fat meals before taking DURANZO as it can decrease the absorption of the medicine.

FAQs

What is Duranzo 50/50mg Tablet 10's?Arrow

Duranzo 50/50mg Tablet 10's is a medication containing two active ingredients, used to treat certain medical conditions. Please consult your doctor for specific uses.

What is Duranzo 50/50mg Tablet 10's used for?Arrow

Duranzo 50/50mg Tablet 10's is used to treat specific medical conditions. Talk to your doctor to find out if it's right for you.

What are the common side effects of Duranzo 50/50mg Tablet 10's?Arrow

Common side effects of Duranzo 50/50mg Tablet 10's may include nausea, vomiting, diarrhea, and stomach pain. Inform your doctor if you experience any persistent or severe side effects.

How should I store Duranzo 50/50mg Tablet 10's?Arrow

Store Duranzo 50/50mg Tablet 10's at room temperature, away from direct sunlight and moisture. Keep out of reach of children and pets.

Can I take Duranzo 50/50mg Tablet 10's with or without food?Arrow

Duranzo 50/50mg Tablet 10's can be taken with or without food, as directed by your doctor.

What happens if I miss a dose of Duranzo 50/50mg Tablet 10's?Arrow

If you miss a dose of Duranzo 50/50mg Tablet 10's, take it as soon as you remember. However, if it is close to your next dose, skip the missed dose and continue with your regular dosing schedule.

Can Duranzo 50/50mg Tablet 10's interact with other medications?Arrow

Duranzo 50/50mg Tablet 10's can interact with other medications. Inform your doctor about all the medications, vitamins, or herbal supplements you are taking.

Does Duranzo 50/50mg Tablet 10's cause dizziness?Arrow

Duranzo 50/50mg Tablet 10's may cause dizziness in some people. Avoid driving or operating machinery if you feel dizzy.

Can I take Duranzo 50/50mg Tablet 10's during pregnancy?Arrow

Consult your doctor before taking Duranzo 50/50mg Tablet 10's if you are pregnant or planning to become pregnant.

How long does it take for Duranzo 50/50mg Tablet 10's to work?Arrow

The time it takes for Duranzo 50/50mg Tablet 10's to work can vary from person to person.

Is Duranzo 50/50mg Tablet 10's a painkiller?Arrow

Consult your doctor to know whether Duranzo 50/50mg Tablet 10's is a painkiller or not.

Can I drink alcohol with Duranzo 50/50mg Tablet 10's?Arrow

Consult your doctor before drinking alcohol with Duranzo 50/50mg Tablet 10's.

What happens if I overdose on Duranzo 50/50mg Tablet 10's?Arrow

Seek immediate medical attention if you suspect you have overdosed on Duranzo 50/50mg Tablet 10's.

Is Duranzo 50/50mg Tablet 10's safe during breastfeeding?Arrow

Consult your doctor before using Duranzo 50/50mg Tablet 10's if you are breastfeeding.

Are there any special precautions I should take while taking Duranzo 50/50mg Tablet 10's?Arrow

Consult your doctor about any special precautions you should take while taking Duranzo 50/50mg Tablet 10's.

What is Duranzo Tab used for?Arrow

Duranzo Tab is generally prescribed for gynecological and hormonal conditions, such as regulating menstrual cycles, managing abnormal uterine bleeding, or treating certain hormone-related symptoms. The exact use depends on its active ingredient and your doctor’s treatment plan. Always follow the indication and instructions given by your healthcare provider and the product leaflet.

How should I take Duranzo Tab?Arrow

Take Duranzo Tab exactly as prescribed by your doctor, usually with water and at the same time each day. It may be taken with or without food unless your doctor advises otherwise. Do not change the dose, do not take extra tablets, and do not extend or shorten the course on your own. If you are unsure about the schedule, ask your doctor or pharmacist for clarification.

What should I do if I miss a dose of Duranzo Tab?Arrow

If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed dose. If you frequently forget doses, talk to your doctor, as this may affect treatment effectiveness.

Can I take Duranzo Tab during pregnancy?Arrow

Use of Duranzo Tab during pregnancy depends on its exact active ingredient and indication. Many hormone-related tablets are not recommended once pregnancy is confirmed, unless specifically prescribed for a pregnancy-related condition by a specialist. If you think you might be pregnant, or if you become pregnant while taking Duranzo Tab, stop taking it and contact your doctor immediately for advice. Do not continue the medicine in pregnancy without medical supervision.

Is Duranzo Tab safe while breastfeeding?Arrow

Safety during breastfeeding depends on the active ingredient and dose. Some hormonal medicines can pass into breast milk and may affect milk production or the nursing infant. Do not start or continue Duranzo Tab while breastfeeding without consulting your doctor. Your doctor will weigh the benefits and potential risks and may suggest an alternative medicine or adjust the timing of doses in relation to breastfeeding.

Can I drink alcohol while taking Duranzo Tab?Arrow

Moderate alcohol intake may be permissible for some patients, but alcohol can increase the risk of side effects such as dizziness, headache, or stomach discomfort, and may worsen underlying liver problems. Because the exact interaction depends on the active ingredient and your health status, it is safer to limit or avoid alcohol while taking Duranzo Tab and to ask your doctor for personalized advice.

Is Duranzo Tab safe for patients with liver problems?Arrow

Many hormonal medicines are processed by the liver and may not be suitable for patients with active liver disease, a history of severe liver impairment, or unexplained jaundice. If you have any liver condition, you must inform your doctor before starting Duranzo Tab. Your doctor may order liver function tests, adjust treatment, or choose an alternative medicine if necessary. Do not use Duranzo Tab in liver disease without medical approval.

Can I take Duranzo Tab if I have kidney disease?Arrow

In mild to moderate kidney impairment, some patients may use hormonal medicines with caution, but this depends on the specific active ingredient and overall health. Severe kidney disease may require dose adjustments or avoidance of certain drugs. If you have any kidney problem, inform your doctor before taking Duranzo Tab. Your doctor will decide whether it is appropriate for you and may monitor your kidney function during treatment.

Is it safe to drive or operate machines while taking Duranzo Tab?Arrow

Duranzo Tab is not primarily known for causing drowsiness, but some people may experience dizziness, headache, visual disturbances, or fatigue, especially when starting treatment or when doses are changed. If you feel dizzy, sleepy, or unwell after taking the tablet, avoid driving, cycling, or operating machinery until you know how the medicine affects you. Always prioritize safety and discuss persistent symptoms with your doctor.

What if I am allergic to similar medicines? Can I still take Duranzo Tab?Arrow

If you have a history of allergy or severe reaction to hormonal medicines or any of the excipients commonly used in tablets, inform your doctor before starting Duranzo Tab. Signs of an allergic reaction can include rash, itching, swelling of the face or throat, severe dizziness, or difficulty breathing. If any of these occur after taking Duranzo Tab, stop the medicine immediately and seek emergency medical care. Do not restart it unless your doctor confirms it is safe.

What side effects can occur with Duranzo Tab?Arrow

Possible side effects may include nausea, mild headache, breast tenderness, mood changes, spotting between periods, or changes in menstrual flow. Some patients may notice bloating, weight changes, or mild fluid retention. Serious side effects such as chest pain, sudden shortness of breath, severe headache, vision changes, or leg swelling are rare but require urgent medical attention. Always report any unusual or severe symptoms to your doctor promptly.

References

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European Medicines Agency (EMA) - Priligy (dapoxetine) EPAR. Contains detailed information on the pharmacology, clinical trials, and safety of dapoxetine. Duranzo contains dapoxetine.

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FDA label for PRILIGY (dapoxetine hydrochloride) tablets. Provides comprehensive information regarding its clinical pharmacology, including mechanism of action, pharmacokinetics, clinical studies, and safety data.

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DrugBank entry for Dapoxetine. A detailed summary of the drug's properties, mechanisms, and interactions.

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NCBI PubMed Central Article: Dapoxetine: a review of its pharmacology and clinical efficacy in the treatment of premature ejaculation. This review article provides a detailed overview of the pharmacology, efficacy, and safety of dapoxetine.

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NCBI PubMed Central Article: Silodosin for the treatment of premature ejaculation: a systematic review and meta-analysis. While focusing on Silodosin, this article could offer insights into the broader context of premature ejaculation treatments, which is the therapeutic area for Duranzo.

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Had a nice experience of buying medicine and other FMCG products ,also got good discount too.

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Nice experience, always!

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Reviewed on 24-02-2023

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(5/5)

Good for generic medicine, quality medicine with affordable rate

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Reviewed on 03-02-2024

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(5/5)


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AJANTA PHARMA LIMITED

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India

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DURANZO 50/50MG TABLET 10'S

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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