DURART-R 450 TABLET 60'S
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DURART-R 450 TABLET 60'S
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DURART-R 450 TABLET 60'S

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DURART-R 450 TABLET 60'S

By MYLAN PHARMACEUTICALS PRIVATE LIMITED

MRP

7793.44

₹4100

47.39 % OFF

₹68.33 Only /

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About DURART-R 450 TABLET 60'S

  • DURART-R 450 TABLET 60'S contains a combination of Darunavir and Ritonavir, both potent antiretroviral drugs belonging to the protease inhibitor class. This medication plays a crucial role in managing HIV infection by bolstering the immune system in adults and children aged three years and older. While it's important to understand that DURART-R 450 TABLET 60'S is not a cure for HIV, it significantly reduces the likelihood of progressing to acquired immunodeficiency syndrome (AIDS) and other HIV-related complications. Regular use, as directed by your healthcare provider, is essential for maintaining its effectiveness.
  • Before commencing treatment with DURART-R 450 TABLET 60'S, inform your doctor about any existing allergies, particularly to Darunavir, Ritonavir, or any other ingredients in the formulation. It is crucial to disclose any pre-existing liver conditions, such as hepatitis B or C, to your physician. Individuals with diabetes should also notify their doctor, as this medication may affect blood sugar levels. Seek immediate medical attention if you experience symptoms of infection like enlarged lymph nodes and fever, or musculoskeletal problems such as joint pain, stiffness, especially in the hip, knee, shoulder, and difficulty in moving. These signs warrant prompt evaluation.
  • If you are 65 years or older, consult with your physician before starting this medication. If you are pregnant, suspect you might be, or are planning to conceive, discuss this with your doctor before initiating treatment with DURART-R 450 TABLET 60'S. Effective contraception is crucial during treatment. Be aware of potential side effects such as swelling in the face and feet, rash, abdominal pain, diarrhea, nausea, vomiting, and back pain. Dizziness can also occur. If any of these side effects persist or worsen, promptly inform your physician for appropriate management. It's also important to adhere to all monitoring and follow-up appointments recommended by your healthcare provider to ensure safe and effective treatment.

Uses of DURART-R 450 TABLET 60'S

  • HIV Infection: This medication helps in the treatment of HIV (Human Immunodeficiency Virus) infection, which attacks the body's immune system.

Side Effects of DURART-R 450 TABLET 60'SArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. Serious side effects include heart problems, severe skin reactions, pancreatitis, increased risk of bleeding, liver problems, and diabetes. Common side effects include skin rash, nausea, vomiting, swelling in the face and body, abdominal pain, diarrhea, back pain, dizziness, and cough or pain in the throat.

  • Heart problems
  • Severe skin reactions
  • Pancreatitis
  • Increased risk of bleeding
  • Liver problems
  • Diabetes
  • Skin rash
  • Nausea, vomiting
  • Swelling in the face and body
  • Abdominal pain, diarrhea
  • Back pain
  • Dizziness
  • Cough, pain in throat

Safety Advice for DURART-R 450 TABLET 60'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Do not take DURART-R 450 TABLET 60'S unless your doctor advised to take these tablets because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.

Dosage of DURART-R 450 TABLET 60'SArrow

  • DURART-R 450 TABLET 60'S is an oral prescription medication, meaning it is taken by mouth and requires a doctor's authorization to obtain. The precise dosage and treatment duration with DURART-R 450 TABLET 60'S will be determined by your doctor, who will consider your specific medical condition, body weight, age, and other relevant health factors. Adhering to your doctor's instructions is essential for safe and effective treatment.
  • For optimal results, always take DURART-R 450 TABLET 60'S exactly as prescribed by your healthcare provider. Consistency is key; try to take the tablet at the same time each day. You can take DURART-R 450 TABLET 60'S either with or without food, as directed by your physician. The presence or absence of food generally does not affect how the medication is absorbed.
  • It is crucial to swallow the tablet whole with a full glass of water. Avoid breaking, chewing, crushing, or otherwise altering the tablet's form before swallowing. These actions can interfere with the drug's intended release mechanism and potentially impact its effectiveness or increase the risk of side effects. If you have difficulty swallowing pills, discuss alternative options with your doctor or pharmacist.

How to store DURART-R 450 TABLET 60'S?Arrow

  • Keep DURART-R 450MG TAB 1X60 away from the reach of children and pets.
  • Store DURART-R 450MG TAB 1X60 at room temperature.

Benefits of DURART-R 450 TABLET 60'SArrow

  • DURART-R 450 TABLET 60'S is a potent antiviral medication combining darunavir and ritonavir, both classified as protease inhibitors. This combination is strategically designed to combat HIV by targeting a crucial enzyme known as protease, essential for the virus's replication cycle.
  • Protease is responsible for cleaving large precursor proteins into smaller, functional proteins that are necessary for assembling new infectious viral particles. By inhibiting protease, DURART-R 450 TABLET 60'S prevents the virus from producing mature, infectious virions. This disruption of the viral life cycle significantly reduces the viral load in the body.
  • Darunavir and ritonavir work synergistically. Ritonavir, while also a protease inhibitor, primarily functions in this combination as a pharmacokinetic booster. It inhibits the enzyme CYP3A4 in the liver, which is responsible for metabolizing darunavir. By slowing down the breakdown of darunavir, ritonavir increases darunavir's concentration in the bloodstream, allowing it to remain active for a longer period and enhancing its antiviral effect.
  • In essence, DURART-R 450 TABLET 60'S effectively sabotages the ability of HIV to replicate and spread within the body by targeting and disabling the protease enzyme. This leads to a reduction in viral load and can improve the patient's overall health and quality of life.

How to use DURART-R 450 TABLET 60'SArrow

  • DURART-R 450 TABLET 60'S is a prescription medication that you take by mouth. Your doctor is the best person to determine the appropriate dosage and duration of treatment. They will consider your specific condition, as well as other factors like your weight and age, to make the right recommendation for you.
  • It is crucial to adhere strictly to your doctor's instructions when taking this medicine. Consistency is key, so try to take the tablet around the same time each day. You can take it with or without food, whichever is easier for you to remember.
  • When taking the tablet, do not break, chew, crush, or cut it. Instead, swallow the whole tablet with a full glass of water. This ensures that the medication is absorbed properly and works as intended. If you have any difficulty swallowing tablets, discuss it with your doctor or pharmacist – they may have suggestions or alternatives that could help.
  • Missing doses or taking medicine incorrectly can reduce the effectiveness. If you accidentally miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.

FAQs

Is DURART-R 450 TABLET 60'S a cure for HIV?Arrow

DURART-R 450 TABLET 60'S is not a cure for HIV. It is an antiretroviral medication that helps control the viral load and slow down the progression of HIV infection. It is essential to continue taking the medication as prescribed, even if you feel well, to maintain the effectiveness of the treatment.

What should you do if you missed a dose of DURART-R 450 TABLET 60'S?Arrow

If you miss a dose of DURART-R 450 TABLET 60'S, take one as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the scheduled dose. Do not take two doses to make up for the missed dose.

When should you report to your healthcare provider?Arrow

Reach out to your healthcare provider if you notice unusual blisters, extreme tiredness, yellowing of skin or eyes, mouth sores, dark urine, fever or conjunctivitis.

What are the required laboratory parameters prior to starting this treatment?Arrow

If you are an adolescent or adult of childbearing potential, your healthcare provider will perform a pregnancy test before prescribing this treatment. Other prominent tests include test for HBV infection, blood sugar levels, liver and kidney parameters.

Does treatment with DURART-R 450 TABLET 60'S cause diabetes?Arrow

DURART-R 450 TABLET 60'S leads to increase in blood glucose and the new onset of diabetes. Tell your physician if you notice extreme thirst or urination during this treatment.

Is there any interaction of DURART-R 450 TABLET 60'S with other drugs?Arrow

NULL interaction of DURART-R 450 TABLET 60'S with other drungs

What advice should I follow while taking DURART-R 450 TABLET 60'S?Arrow

Discuss effective contraception methods with your doctor, along with fertility concerns. DURART-R 450 TABLET 60'S might reduce its effectiveness in contraception; alternative methods of non-hormonal contraception are recommended. Do not stop the medicine until your doctor advises. Regular blood tests are recommended to evaluate your liver function and hepatitis B virus level. Notify your doctor if you experience any serious side effects. You are doctor may change your dose or stop the treatment. Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. your doctor has prescribed at the right time of day and in the correct order. Do not stop using your medicine unless your doctor tells you to. Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

What is DURART-R 450 TABLET 60'S made of?Arrow

DURART-R 450 TABLET 60'S is made of DARUNAVIR,RITONAVIR.

For what kind of infections DURART-R 450 TABLET 60'S is used to treat?Arrow

DURART-R 450 TABLET 60'S is prescribed for treating Infectious Diseases.

References

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Janssen Pharmaceuticals, PREZISTA prescribing information

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AbbVie Corporation, NORVIR prescribing information

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Capetti et al., A dual regimen of ritonavir/darunavir plus dolutegravir for rescue or simplification of rescue therapy: 48 weeks’ observational data, BMC Infectious Diseases (2017) 17:658

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Marketer / Manufacturer Details

MYLAN PHARMACEUTICALS PRIVATE LIMITED

Country of Origin -

India

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₹4100

47.39 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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