DUZELA M 30MG CAPSULE 10'S
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DUZELA M 30MG CAPSULE 10'SDUZELA M 30MG CAPSULE 10'SDUZELA M 30MG CAPSULE 10'S
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DUZELA M 30MG CAPSULE 10'S

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DUZELA M 30MG CAPSULE 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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210.93

₹179.29

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Product DetailsArrow

Content Reviewed By:

Dr. Amit Patel

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About DUZELA M 30MG CAPSULE 10'S

  • DUZELA M 30MG CAPSULE 10'S is a combination medicine used to treat various conditions, primarily focusing on nerve-related pain (neuropathic pain) and major depressive disorder. It contains two active ingredients: Duloxetine and Methylcobalamin.
  • Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It works by increasing the levels of serotonin and norepinephrine, two natural chemicals in the brain that help regulate mood and pain. By balancing these neurotransmitters, Duloxetine helps to alleviate symptoms of depression and reduce the sensation of pain caused by nerve damage.
  • Methylcobalamin is a form of vitamin B12. It plays a crucial role in nerve health and regeneration. In DUZELA M, Methylcobalamin helps to repair damaged nerves, improve nerve function, and reduce neuropathic pain symptoms such as burning, tingling, and numbness. This is particularly beneficial in conditions like diabetic neuropathy, where high blood sugar levels can damage nerves.
  • The combination of Duloxetine and Methylcobalamin in DUZELA M provides a synergistic effect, addressing both the psychological and neurological aspects of pain and depression. This can lead to more effective symptom management and an improved quality of life for patients.
  • DUZELA M 30MG CAPSULE is typically prescribed by a healthcare professional who will determine the appropriate dosage and duration of treatment based on individual patient needs. It is important to follow the doctor's instructions carefully and to discuss any concerns or potential side effects with them. Common side effects may include nausea, dry mouth, constipation, dizziness, and fatigue. This medication should not be stopped abruptly, as it may lead to withdrawal symptoms.

Uses of DUZELA M 30MG CAPSULE 10'S

  • Treatment of Depression
  • Treatment of Generalized Anxiety Disorder
  • Treatment of Neuropathic Pain
  • Treatment of Fibromyalgia
  • Treatment of Diabetic Neuropathy
  • Treatment of Chronic Musculoskeletal Pain

How DUZELA M 30MG CAPSULE 10'S Works

  • DUZELA M 30MG CAPSULE 10'S is a combination medication containing Duloxetine and Methylcobalamin, designed to address conditions like neuropathic pain and major depressive disorder. Understanding how each component works is crucial to appreciating the therapeutic effects of this capsule.
  • **Duloxetine:** Duloxetine is a Serotonin-Norepinephrine Reuptake Inhibitor (SNRI). It primarily functions by preventing the reabsorption (reuptake) of serotonin and norepinephrine in the brain. These neurotransmitters are vital for mood regulation, pain modulation, and overall mental well-being. By inhibiting their reuptake, duloxetine effectively increases the concentration of these neurotransmitters in the synaptic cleft (the space between nerve cells). This enhanced neurotransmitter activity leads to improved mood, reduced pain perception, and alleviation of depressive symptoms. Duloxetine's impact on pain is particularly relevant in conditions like diabetic neuropathy, where nerve damage causes persistent pain signals.
  • **Methylcobalamin:** Methylcobalamin is a form of Vitamin B12 that plays a critical role in nerve health and function. It acts through several mechanisms to support the nervous system. Primarily, it aids in the myelination process, which is the formation of the myelin sheath around nerve fibers. This myelin sheath acts as an insulator, enabling faster and more efficient transmission of nerve impulses. In conditions like peripheral neuropathy, nerve damage can disrupt myelin integrity, leading to impaired nerve function and pain. Methylcobalamin helps to repair and maintain the myelin sheath, thereby improving nerve conduction and reducing neuropathic pain. Furthermore, Methylcobalamin is involved in various metabolic pathways essential for nerve cell health and regeneration. It contributes to the synthesis of nucleic acids and proteins needed for nerve cell repair and growth. It also acts as a cofactor for certain enzymes involved in nerve function.
  • In summary, DUZELA M 30MG CAPSULE 10'S works by combining the mood-enhancing and pain-reducing effects of duloxetine with the nerve-regenerating and supportive actions of methylcobalamin. Duloxetine increases serotonin and norepinephrine levels to improve mood and reduce pain signals, while methylcobalamin supports nerve health by promoting myelination and nerve cell regeneration. This synergistic action makes DUZELA M 30MG CAPSULE 10'S an effective treatment option for neuropathic pain and major depressive disorder, by targeting both the underlying mood imbalances and the nerve damage contributing to pain.

Side Effects of DUZELA M 30MG CAPSULE 10'SArrow

Common side effects of Duzele M 30mg Capsule may include nausea, dry mouth, constipation, decreased appetite, fatigue, drowsiness, increased sweating, dizziness, headache, blurred vision, and sexual dysfunction (decreased libido, erectile dysfunction, or delayed ejaculation). Less common but more serious side effects can include liver problems (abdominal pain, jaundice, dark urine), changes in mood or behavior (anxiety, agitation, panic attacks, insomnia, irritability, hostility, impulsivity, restlessness, mania, hypomania), serotonin syndrome (confusion, hallucinations, seizures, rapid changes in blood pressure, increased heart rate, fever, overactive reflexes, nausea, vomiting, diarrhea), increased blood pressure, angle-closure glaucoma, and suicidal thoughts or behaviors (especially in young adults). Allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing) are also possible. Weight gain or weight loss may also occur. This is not an exhaustive list, and it is crucial to consult a doctor if any unusual or persistent symptoms occur while taking this medication.

Safety Advice for DUZELA M 30MG CAPSULE 10'SArrow

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Allergies

Consult a Doctor

Consult your doctor if you have allergies with Duzela M 30mg Capsule 10'S.

Dosage of DUZELA M 30MG CAPSULE 10'SArrow

  • The recommended dosage of DUZELA M 30MG CAPSULE 10'S varies depending on the individual's condition, severity of symptoms, and response to treatment. It is crucial to adhere strictly to your doctor's instructions regarding dosage and duration of treatment. Generally, DUZELA M is initiated at a low dose to minimize potential side effects and then gradually increased as needed. The typical starting dose for depression or anxiety disorders is 30mg once daily.
  • Your physician may adjust the dose based on your individual needs, usually in increments of 30mg. The maximum recommended daily dose is typically 60mg. It's important to note that it may take several weeks for the full therapeutic effect of DUZELA M to be realized. Do not increase or decrease the dose without consulting your doctor, even if you don't feel immediate improvement.
  • DUZELA M should be swallowed whole with water, and it can be taken with or without food. Consistency in taking the medication at the same time each day is highly recommended to maintain a stable level of the drug in your system. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. For discontinuing DUZELA M, your doctor will gradually reduce the dosage to prevent withdrawal symptoms.
  • Take 'DUZELA M 30MG CAPSULE 10'S' only as per the prescription by your physician only

What if I miss my dose of DUZELA M 30MG CAPSULE 10'S?Arrow

  • If you miss a dose of DUZELA M 30MG CAPSULE 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store DUZELA M 30MG CAPSULE 10'S?Arrow

  • Keep DUZELA M 30MG CAP 1X10 away from the reach of children and pets.
  • Store DUZELA M 30MG CAP 1X10 at room temperature.

Benefits of DUZELA M 30MG CAPSULE 10'SArrow

  • DUZELA M 30MG CAPSULE 10'S is a combination medicine primarily used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve damage or injury to the nerves that transmit information to the brain and spinal cord from the skin, muscles, and other parts of the body. It is typically caused by nerve damage, infections, or other conditions.
  • The medication's benefits stem from its dual-action mechanism. Duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI), works by increasing the levels of these neurotransmitters in the brain. This helps to regulate mood and reduce the perception of pain. Methylcobalamin, a form of vitamin B12, is essential for nerve health and function. It helps to regenerate damaged nerves and improve nerve conduction, further alleviating neuropathic pain.
  • DUZELA M 30MG CAPSULE 10'S effectively manages diabetic neuropathy, a common complication of diabetes that causes nerve damage, leading to pain, numbness, and tingling in the hands and feet. By improving nerve function and reducing pain signals, this medicine can significantly improve the quality of life for individuals with diabetic neuropathy.
  • Beyond diabetic neuropathy, DUZELA M 30MG CAPSULE 10'S also provides relief from other types of neuropathic pain, such as postherpetic neuralgia (nerve pain after shingles) and trigeminal neuralgia (severe facial pain). Its ability to modulate pain pathways and promote nerve regeneration makes it a valuable option for individuals suffering from various nerve-related pain conditions.
  • Furthermore, DUZELA M 30MG CAPSULE 10'S has shown efficacy in managing fibromyalgia, a chronic condition characterized by widespread musculoskeletal pain, fatigue, and tenderness in localized areas. The pain-reducing and mood-regulating effects of duloxetine, combined with the nerve-supporting properties of methylcobalamin, can help alleviate the symptoms of fibromyalgia and improve overall well-being.
  • In addition to its pain-relieving properties, DUZELA M 30MG CAPSULE 10'S may also improve mood and reduce symptoms of depression and anxiety, which are often associated with chronic pain conditions. By increasing serotonin and norepinephrine levels in the brain, duloxetine can help regulate mood and promote a sense of well-being, further enhancing the overall therapeutic effect of the medication.
  • DUZELA M 30MG CAPSULE 10'S offers a comprehensive approach to managing neuropathic pain and related conditions, addressing both the underlying nerve damage and the associated symptoms of pain, mood disturbances, and reduced quality of life. Always consult with a healthcare professional to determine if DUZELA M 30MG CAPSULE 10'S is appropriate for your specific condition and to discuss any potential risks or side effects.

How to use DUZELA M 30MG CAPSULE 10'SArrow

  • DUZELA M 30MG CAPSULE 10'S should be taken exactly as prescribed by your doctor. It's typically recommended to take it orally with water, preferably at the same time each day to maintain a consistent level of medication in your system. Consistency is key for optimal results.
  • Swallow the capsule whole; do not crush, chew, or open it, as this can affect how the medication is released and may increase the risk of side effects. If you have difficulty swallowing capsules, discuss this with your doctor or pharmacist for alternative options.
  • The dosage of DUZELA M 30MG CAPSULE 10'S will depend on your individual condition and response to treatment. Your doctor will determine the appropriate dose for you. Do not change your dose or stop taking the medication without consulting your doctor, even if you feel better. Suddenly stopping the medication can lead to withdrawal symptoms.
  • DUZELA M 30MG CAPSULE 10'S can be taken with or without food. However, taking it with food may help reduce the risk of nausea, which is a potential side effect. If you experience persistent nausea, discuss it with your doctor.
  • Avoid alcohol while taking DUZELA M 30MG CAPSULE 10'S, as it can increase the risk of side effects such as drowsiness and liver problems. Also, inform your doctor about all other medications, supplements, or herbal products you are taking to avoid potential drug interactions.
  • It may take several weeks to experience the full benefits of DUZELA M 30MG CAPSULE 10'S. Continue taking the medication as prescribed, even if you don't notice an immediate improvement. Regular follow-up appointments with your doctor are important to monitor your progress and adjust your treatment plan if needed.
  • If you miss a dose of DUZELA M 30MG CAPSULE 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.

Quick Tips for DUZELA M 30MG CAPSULE 10'SArrow

  • Take DUZELA M 30MG CAPSULE 10'S as prescribed by your doctor. It's usually taken once daily, but the dosage and timing can vary depending on your specific condition and response to treatment. Consistency is key, so try to take it at the same time each day to maintain a steady level of medication in your system. This helps ensure the medication works effectively throughout the day.
  • Be patient, it can take several weeks (2-4 weeks) to feel the full effects of DUZELA M 30MG CAPSULE 10'S. Don't get discouraged if you don't notice an immediate improvement. Continue taking the medication as directed, and communicate with your doctor about your progress and any concerns you may have. They can adjust your treatment plan if necessary.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting DUZELA M 30MG CAPSULE 10'S. This helps prevent potentially dangerous drug interactions. Some medications can increase the risk of side effects or reduce the effectiveness of DUZELA M 30MG CAPSULE 10'S. A comprehensive medication review is crucial for your safety.
  • Monitor yourself for potential side effects and report any concerning symptoms to your doctor promptly. Common side effects may include nausea, dry mouth, constipation, fatigue, dizziness, and changes in sexual function. While some side effects may subside over time, it's essential to discuss any persistent or bothersome symptoms with your doctor. They can help manage side effects and ensure your comfort.
  • Avoid abrupt discontinuation of DUZELA M 30MG CAPSULE 10'S. Stopping the medication suddenly can lead to withdrawal symptoms, such as dizziness, headache, nausea, and anxiety. If you need to discontinue the medication, your doctor will gradually reduce the dosage over time to minimize these effects. Always consult with your doctor before making any changes to your medication regimen.

Food Interactions with DUZELA M 30MG CAPSULE 10'SArrow

  • DUZELA M 30MG CAPSULE 10'S may be taken with or without food. However, it is best to take it at a consistent time each day to maintain a steady level of medication in your body. Be cautious about consuming alcohol while taking this medication, as it can increase the risk of liver damage and intensify some side effects.

FAQs

What is DUZELA M 30MG CAPSULE 10'S and what is it used for?Arrow

DUZELA M 30MG CAPSULE 10'S is a combination medicine used to treat neuropathic pain associated with depression and anxiety. It contains Duloxetine and Methylcobalamin.

What are the main ingredients in DUZELA M 30MG CAPSULE 10'S?Arrow

The two main ingredients in DUZELA M 30MG CAPSULE 10'S are Duloxetine and Methylcobalamin.

What are the common side effects of DUZELA M 30MG CAPSULE 10'S?Arrow

Common side effects of DUZELA M 30MG CAPSULE 10'S may include nausea, vomiting, constipation, dry mouth, dizziness, and sleepiness.

Is DUZELA M 30MG CAPSULE 10'S safe?Arrow

DUZELA M 30MG CAPSULE 10'S is generally safe when used as directed by a healthcare professional. Talk to your doctor if you have any concerns.

How should DUZELA M 30MG CAPSULE 10'S be stored?Arrow

DUZELA M 30MG CAPSULE 10'S should be stored at room temperature, away from heat and light.

Is it safe to take more than the recommended dose of DUZELA M 30MG CAPSULE 10'S?Arrow

It is not safe to take more than the recommended dose. Overdosing can lead to serious side effects.

What should I do if I miss a dose of DUZELA M 30MG CAPSULE 10'S?Arrow

If you miss a dose, take it as soon as you remember unless it is close to your next scheduled dose. In that case, skip the missed dose and follow your regular dosing schedule.

Can pregnant or breastfeeding women take DUZELA M 30MG CAPSULE 10'S?Arrow

Pregnant or breastfeeding women should consult their doctor before taking DUZELA M 30MG CAPSULE 10'S.

Can DUZELA M 30MG CAPSULE 10'S interact with other medications?Arrow

DUZELA M 30MG CAPSULE 10'S can interact with certain other medications. Tell your doctor about all the medications you are taking.

What are other brand names for Duloxetine?Arrow

Some other brand names for Duloxetine include Cymbalta and Dulan.

What is Methylcobalamin used for?Arrow

Methylcobalamin is a form of Vitamin B12 and is used to treat Vitamin B12 deficiency and support nerve health.

How long does it take for DUZELA M 30MG CAPSULE 10'S to start working?Arrow

It may take a few weeks for DUZELA M 30MG CAPSULE 10'S to start working.

Can I drink alcohol while taking DUZELA M 30MG CAPSULE 10'S?Arrow

Drinking alcohol while taking DUZELA M 30MG CAPSULE 10'S may increase the risk of side effects.

What are the alternatives to DUZELA M 30MG CAPSULE 10'S?Arrow

Alternatives to DUZELA M 30MG CAPSULE 10'S include other antidepressants, pain relievers, and Vitamin B12 supplements.

Is DUZELA M 30MG CAPSULE 10'S addictive?Arrow

DUZELA M 30MG CAPSULE 10'S is not addictive, but stopping it abruptly can cause withdrawal symptoms.

References

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Duloxetine and Methylcobalamin Combination in the Treatment of Painful Diabetic Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Trial

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CYMBALTA® (duloxetine hydrochloride) Delayed-release capsules prescribing information.

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Duloxetine DrugBank entry

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Cymbalta EPAR (European Medicines Agency)

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Methylcobalamin: A Potential Vitamin of Pain Killer.

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Methylcobalamin DrugBank entry

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Methylcobalamin - an overview | ScienceDirect Topics

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SUN PHARMACEUTICAL INDUSTRIES LTD

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DUZELA M 30MG CAPSULE 10'S

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