EGLUCENT MIX 25 KWIKPEN

How EGLUCENT MIX 25 KWIKPEN Works

• Eglucent Mix 25 KwikPen is a pre-filled insulin pen containing a combination of rapid-acting (insulin lispro) and intermediate-acting (insulin lispro protamine) insulins. This combination helps to manage blood sugar levels effectively throughout the day by addressing both mealtime and background insulin needs. Insulin lispro starts working quickly, helping to control blood sugar spikes after meals, while insulin lispro protamine provides a longer-lasting effect, maintaining stable blood sugar levels between meals and during the night.
• Insulin lispro, the rapid-acting component, is a modified form of human insulin. Its altered molecular structure allows for faster absorption from the injection site into the bloodstream compared to regular human insulin. This rapid absorption enables it to be taken shortly before or even after meals, mimicking the natural insulin response of a healthy pancreas. It binds to insulin receptors on cells throughout the body, signaling them to absorb glucose from the blood. This process lowers blood glucose levels, preventing hyperglycemia (high blood sugar).
• Insulin lispro protamine, the intermediate-acting component, is created by combining insulin lispro with protamine, a protein that slows down its absorption. This results in a longer duration of action, providing a basal (background) level of insulin that helps to control blood sugar levels for up to 24 hours. The protamine allows for a slow, steady release of insulin lispro into the bloodstream, thus maintaining a consistent level of insulin activity, bridging the gaps between mealtimes and during periods of fasting.
• When injected subcutaneously (under the skin), Eglucent Mix 25 KwikPen releases insulin lispro for immediate post-meal glucose control, followed by a gradual release of insulin lispro protamine for sustained glucose management. The 25 in the name indicates that 25% of the total insulin is rapid-acting insulin lispro, while the remaining 75% is intermediate-acting insulin lispro protamine. This fixed ratio is designed to simplify insulin therapy, especially for individuals who require a combination of both rapid- and intermediate-acting insulins. Always use as directed by your healthcare provider.
• Eglucent Mix 25 KwikPen works by facilitating glucose uptake by cells, reducing glucose production in the liver, and inhibiting the breakdown of fat (lipolysis) and protein (proteolysis). This comprehensive action helps to regulate the body's glucose metabolism, ensuring that blood sugar levels remain within the target range. Regular monitoring of blood glucose levels, adherence to a healthy diet, and consistent exercise are essential components of effective diabetes management when using Eglucent Mix 25 KwikPen.

Like all medicines, EGLUCENT MIX 25 KWIKPEN can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Hypoglycemia (low blood sugar): This is the most common side effect. Symptoms can include sweating, trembling, anxiety, blurred vision, rapid heartbeat, dizziness, and confusion. Severe hypoglycemia can lead to unconsciousness and, if untreated, can be life-threatening. * Injection site reactions: Redness, swelling, itching, or pain at the injection site. * Lipodystrophy: Changes in fat tissue at the injection site (lipoatrophy - thinning of fat, or lipohypertrophy - thickening of fat) can occur if injections are not rotated within the same area. **Uncommon side effects (may affect up to 1 in 100 people):** * Allergic reactions: Skin rash, itching, hives. * Edema: Swelling of ankles and feet. **Rare side effects (may affect up to 1 in 1,000 people):** * Severe allergic reaction (anaphylaxis): Symptoms can include difficulty breathing, wheezing, rapid heartbeat, sweating, and a drop in blood pressure. Seek immediate medical attention. **Very rare side effects (may affect up to 1 in 10,000 people):** * Visual disturbances: Temporary visual impairment may occur at the beginning of insulin therapy. * Myalgia: Muscle pain. **Other possible side effects:** * Weight gain: Insulin can cause weight gain. * Peripheral neuropathy: Nerve damage causing pain, numbness, and tingling in the hands and feet. * Sodium retention: This can lead to swelling. **Important considerations:** * Always monitor your blood sugar levels regularly. * If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. * Learn to recognize the signs and symptoms of hypoglycemia and hyperglycemia (high blood sugar) and how to treat them. * Rotate injection sites to help prevent skin changes, such as thickening under the skin.

• If you miss a dose of EGLUCENT MIX 25 KWIKPEN, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
• It is important to maintain consistent blood sugar levels. Monitor your blood sugar regularly and adjust your diet and exercise as needed.

• Keep EGLUCENT MIX 25 KWIKPEN away from the reach of children and pets.
• Store EGLUCENT MIX 25 KWIKPEN in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Type:** Eglucent Mix 25 KwikPen contains a mix of rapid-acting and intermediate-acting insulin. This means it starts working quickly to cover meals and also provides a longer-lasting background insulin coverage. Understanding this dual action is key to managing your blood sugar effectively.
• **Proper Storage is Crucial:** Store your Eglucent Mix 25 KwikPen in the refrigerator (2°C to 8°C or 36°F to 46°F) until you are ready to use it. Once in use, the KwikPen can be stored at room temperature (below 30°C or 86°F) for up to 28 days. Avoid exposing it to extreme heat or direct sunlight. Always check the expiration date before use.
• **Prime Your Pen Before Each Injection:** Before each injection, prime the pen by dialing up 2 units and injecting the insulin into the air. Repeat this process until a drop of insulin appears at the needle tip. This ensures that the pen is working correctly and delivers the accurate dose. Air bubbles can affect the accuracy of your dose.
• **Rotate Injection Sites Regularly:** To prevent skin thickening or pitting (lipodystrophy), rotate your injection sites within the same general area (e.g., abdomen, thigh, or upper arm). Use a different spot each time you inject. Consistent rotation helps ensure proper insulin absorption and prevents skin problems. Consult your doctor or diabetes educator for suitable injection sites.
• **Monitor Your Blood Sugar Levels Frequently:** Regularly check your blood sugar levels as directed by your doctor. This will help you understand how Eglucent Mix 25 KwikPen is affecting your blood sugar and allow you to adjust your diet, exercise, or insulin dosage as needed. Keeping a log of your blood sugar readings can be helpful for your doctor to make informed decisions about your treatment plan.
• **Be Aware of Hypoglycemia (Low Blood Sugar):** Learn to recognize the symptoms of hypoglycemia, such as sweating, shaking, dizziness, and confusion. Always carry a source of fast-acting sugar (e.g., glucose tablets, juice) with you in case your blood sugar drops too low. If you experience hypoglycemia, treat it immediately and inform your doctor.
• **Consult Your Doctor Before Making Changes:** Never change your insulin dosage or injection schedule without consulting your doctor. Self-adjusting your medication can lead to serious health problems. Your doctor can help you adjust your treatment plan based on your individual needs and blood sugar levels.
• **Use the Right Needle Size:** Ensure you are using the correct needle size for your pen. Needles are available in various lengths, and the appropriate size depends on your body type and injection technique. Your doctor or diabetes educator can advise you on the best needle size for you to ensure proper insulin delivery under the skin.
• **Check Insulin Appearance:** Inspect the insulin in your Eglucent Mix 25 KwikPen before each use. It should be uniformly cloudy or milky white. Do not use the insulin if it appears clear, has clumps, or if solid particles are visible. These changes could indicate that the insulin has been damaged or is no longer effective. Always use a new pen if you notice any abnormalities.

• Eglucent Mix 25 Kwikpen should be injected 15 minutes before a meal or immediately after starting a meal.
• The timing of insulin injection in relation to food intake is crucial for managing blood sugar levels effectively.
• Consistency in meal timings and carbohydrate intake is important when using this medication to prevent fluctuations in blood sugar.
• Consult your doctor or diabetes educator for personalized advice on how to adjust your insulin dosage based on your dietary habits and activity levels.
• Be aware that changes in your diet, such as consuming high-fat or high-sugar foods, can affect your blood sugar levels and may require adjustments to your insulin dosage.
• Alcohol consumption can also affect blood sugar levels; therefore, it is essential to monitor blood sugar closely and adjust insulin dosage accordingly if you consume alcohol.
• If you experience any unexpected changes in blood sugar levels, discuss your dietary habits with your doctor to identify potential contributing factors and adjust your treatment plan as needed.