ENACE D 5MG TABLET 30'S

How ENACE D 5MG TABLET 30'S Works

• ENACE D 5MG TABLET 30'S is a combination medication primarily used to manage hypertension (high blood pressure). It combines two active ingredients: enalapril maleate and hydrochlorothiazide. Each component works differently to achieve a synergistic effect in lowering blood pressure.
• Enalapril maleate belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. ACE inhibitors work by blocking the action of ACE, an enzyme in the body responsible for converting angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor, meaning it narrows blood vessels, leading to increased blood pressure. By inhibiting ACE, enalapril reduces the production of angiotensin II, causing blood vessels to relax and widen. This vasodilation reduces the resistance against which the heart must pump, thereby lowering blood pressure. Enalapril also reduces the levels of aldosterone, a hormone that causes the kidneys to retain sodium and water. By reducing aldosterone, enalapril promotes the excretion of sodium and water, further contributing to a decrease in blood volume and blood pressure.
• Hydrochlorothiazide is a thiazide diuretic, often referred to as a 'water pill.' It works directly on the kidneys to increase the excretion of sodium and chloride (salts) and water from the body. This action reduces the volume of fluid in the bloodstream, which in turn lowers blood pressure. Hydrochlorothiazide inhibits the reabsorption of sodium and chloride in the distal convoluted tubule of the nephron (the functional unit of the kidney). This inhibition leads to increased sodium and water excretion. Additionally, hydrochlorothiazide has a mild vasodilatory effect on blood vessels, contributing to its blood pressure-lowering effects. The combination of enalapril and hydrochlorothiazide provides a more effective approach to managing hypertension than using either medication alone. Enalapril counteracts some of the side effects of hydrochlorothiazide, such as potassium loss, while hydrochlorothiazide enhances the blood pressure-lowering effects of enalapril.
• In summary, ENACE D 5MG TABLET 30'S lowers blood pressure by reducing the production of angiotensin II (through enalapril), which relaxes blood vessels and reduces sodium and water retention, and by increasing the excretion of sodium and water (through hydrochlorothiazide), which reduces blood volume. This dual mechanism of action makes it an effective treatment option for individuals with hypertension.

The following side effects have been reported with ENACE D 5MG TABLET 30'S. Not all side effects are common, and some may be rare. If you experience any troublesome or persistent side effects, consult your doctor. **Common Side Effects:** * Dizziness * Headache * Fatigue * Dry cough * Nausea * Hypotension (low blood pressure) **Uncommon Side Effects:** * Orthostatic hypotension (dizziness upon standing) * Rapid heartbeat * Palpitations * Nervousness * Paresthesia (numbness or tingling) * Vertigo * Tinnitus (ringing in the ears) * Blurred vision * Diarrhea * Constipation * Vomiting * Abdominal pain * Dry mouth * Dyspepsia (indigestion) * Skin rash * Pruritus (itching) * Urticaria (hives) * Angioedema (swelling of the face, lips, tongue, or throat) * Impotence * Muscle cramps * Hyperkalemia (high potassium levels) * Increased creatinine * Increased blood urea **Rare Side Effects:** * Agranulocytosis (low white blood cell count) * Neutropenia (low neutrophil count) * Thrombocytopenia (low platelet count) * Bone marrow depression * Anemia * Hemolytic anemia * Liver dysfunction * Jaundice * Pancreatitis * Acute renal failure * Pulmonary edema * Bronchospasm * Stevens-Johnson syndrome * Toxic epidermal necrolysis * Systemic lupus erythematosus * Erythema multiforme * Psoriasis * Photosensitivity * Alopecia (hair loss) * Gynaecomastia (enlargement of male breast tissue) * Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH) * Taste disturbances * Depression * Confusion

• If you miss a dose of ENACE D 5MG TABLET 30'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep ENACE D 5MG TAB 1X30 away from the reach of children and pets.
• Store ENACE D 5MG TAB 1X30 at room temperature.

• Take ENACE D 5MG TABLET 30'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting them, as this can affect your blood pressure control and overall health. Consistent adherence to the prescribed regimen is key for optimal results.
• Maintain a healthy lifestyle while taking ENACE D 5MG TABLET 30'S. This includes following a balanced diet low in sodium and saturated fats, engaging in regular physical activity (such as brisk walking or cycling), and limiting alcohol consumption. A healthy lifestyle complements the medication's effects in managing your blood pressure.
• Monitor your blood pressure regularly at home using a reliable blood pressure monitor. Keep a log of your readings and share them with your doctor during your appointments. This helps your doctor assess the effectiveness of ENACE D 5MG TABLET 30'S and make any necessary adjustments to your treatment plan. Consistent monitoring provides valuable insights into your blood pressure control.
• Be aware of potential side effects of ENACE D 5MG TABLET 30'S, such as dizziness, lightheadedness, or a persistent dry cough. If you experience any bothersome side effects, notify your doctor promptly. They can provide guidance on managing these effects or consider alternative medications if needed. Do not hesitate to discuss any concerns with your healthcare provider.
• Store ENACE D 5MG TABLET 30'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Proper storage ensures the medication remains effective and safe for use. Check the expiration date before taking each dose and discard any expired medication according to your local regulations.
• Stay hydrated by drinking plenty of water throughout the day, especially when taking ENACE D 5MG TABLET 30'S. Adequate hydration supports healthy blood volume and can help prevent dizziness or lightheadedness. Aim for at least 8 glasses of water daily, unless your doctor advises otherwise.
• Avoid sudden changes in posture, such as standing up quickly from a sitting or lying position, as this can cause a sudden drop in blood pressure and lead to dizziness or fainting. Rise slowly and steadily to minimize the risk of orthostatic hypotension, a common side effect of blood pressure medications.
• Inform your doctor and dentist about all medications you are taking, including ENACE D 5MG TABLET 30'S, before any surgery or dental procedure. This is important because certain medications can interact with anesthesia or other drugs used during the procedure. Providing a complete medication list ensures your safety and prevents potential complications.

• ENACE D 5MG TABLET 30'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels and maximize its effectiveness.
• Avoid excessive intake of salt as it can increase blood pressure and reduce the effectiveness of ENACE D 5MG TABLET 30'S. Limit consumption of high-sodium foods like processed snacks, canned soups, and fast food.
• Potassium levels should be monitored as this medication can affect potassium levels in the body. Consult your doctor about dietary modifications, especially if you consume potassium supplements or foods high in potassium (e.g., bananas, oranges, spinach).
• Maintain adequate hydration. Drinking plenty of water helps in maintaining overall health and supports the medication's effectiveness.
• Alcohol consumption should be moderated as it can lower blood pressure and may increase the risk of dizziness or lightheadedness when taken with ENACE D 5MG TABLET 30'S.