ENBREL 25MG INJECTION
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ENBREL 25MG INJECTION
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ENBREL 25MG INJECTION

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ENBREL 25MG INJECTION

By PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED

MRP

17400

₹8333

52.11 % OFF

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Product DetailsArrow

About ENBREL 25MG INJECTION

  • ENBREL 25MG INJECTION contains Etanercept as its active ingredient. Marketed as ENBREL, this potent TNF inhibitor effectively addresses various autoimmune conditions, including rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis. Rheumatoid arthritis, an autoimmune disorder, manifests as chronic joint inflammation, resulting in pain, swelling, and potential joint deformity.
  • Psoriatic arthritis is an inflammatory joint condition that affects some individuals with psoriasis, leading to joint pain, stiffness, and swelling. Ankylosing spondylitis, a type of arthritis primarily impacting the spine, causes pain, stiffness, and potential vertebral fusion, reducing flexibility. Juvenile idiopathic arthritis encompasses chronic arthritic conditions affecting children under 16, causing joint inflammation, pain, and potential damage.
  • ENBREL 25MG INJECTION works by suppressing the immune system's overactive response and reducing inflammation, thus alleviating the symptoms of these chronic inflammatory diseases. The medication has proven highly effective in managing these conditions, but potential side effects should be considered, including injection site reactions, infections, headaches, and allergic reactions. It is crucial to promptly consult a healthcare professional if any adverse reactions are experienced. Regular monitoring during treatment is essential to ensure safety and efficacy.
  • ENBREL 25MG INJECTION can be prescribed for pediatric and elderly patients under proper medical supervision. It is approved for treating juvenile idiopathic arthritis in children. It can also effectively manage symptoms in older adults with autoimmune diseases when administered correctly. Individualized treatment plans and careful monitoring are crucial for pediatric and elderly patients to optimize safety and effectiveness. The use of ENBREL 25MG INJECTION should be part of a comprehensive treatment approach, potentially involving physical therapy and lifestyle adjustments, to maximize the therapeutic benefits and improve the patient's overall well-being.

Uses of ENBREL 25MG INJECTION

  • ENBREL 25MG INJECTION is used to treat the following: Rheumatoid arthritis, a chronic inflammatory disorder affecting many joints, causing pain, swelling, and stiffness.
  • Plaque psoriasis, a skin condition causing red, itchy, scaly patches, commonly on the elbows, knees, scalp, and trunk.
  • Psoriatic arthritis, a form of arthritis that affects some people who have psoriasis, causing joint pain, stiffness, and swelling.
  • Ankylosing spondylitis, an inflammatory arthritis affecting the spine and large joints, causing pain and stiffness.
  • Juvenile idiopathic arthritis, a type of arthritis in children that causes joint pain, swelling, and stiffness.
  • Non-radiographic axial spondyloarthritis, a type of inflammatory arthritis primarily affecting the spine, causing back pain and stiffness even without visible damage on X-rays.

Side Effects of ENBREL 25MG INJECTIONArrow

Like all medications, ENBREL 25MG INJECTION can cause side effects, though not everyone will experience them.

  • Serious infections
  • Tuberculosis (TB) reactivation
  • Hepatitis B reactivation
  • Neurological events
  • Allergic reactions
  • Injection site reactions
  • Upper respiratory infections
  • Headache
  • Nausea

Safety Advice for ENBREL 25MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

The safety of ENBREL 25MG INJECTION during pregnancy is not fully established, and its use should be carefully discussed with a healthcare provider, weighing potential risks and benefits for each case.

Dosage of ENBREL 25MG INJECTIONArrow

  • ENBREL 25MG INJECTION can be administered through two primary methods: subcutaneous injection and intravenous infusion. Subcutaneous injection involves injecting the medication directly under the skin, typically in areas like the thigh or abdomen. This method is often preferred for its convenience, allowing patients to self-administer the medication at home after proper training from a healthcare professional.
  • Intravenous infusion, on the other hand, requires the medication to be administered directly into a vein. This is typically done in a clinical setting, such as a hospital or infusion center, by trained medical personnel. The choice between subcutaneous injection and intravenous infusion depends on several factors, including the patient's specific medical condition, their preferences, and the prescribing healthcare provider's recommendation.
  • Both methods have demonstrated efficacy in treating autoimmune diseases, offering patients a flexible approach to managing their condition. The healthcare provider will assess the patient's overall health, disease severity, and other relevant factors to determine the most appropriate administration route. It's crucial for patients to adhere to the prescribed method and schedule for optimal therapeutic outcomes.

How to store ENBREL 25MG INJECTION?Arrow

  • Keep ENBREL 25MG INJ away from the reach of children and pets.
  • Store ENBREL 25MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ENBREL 25MG INJECTIONArrow

  • ENBREL 25MG INJECTION operates through a sophisticated mechanism as a tumor necrosis factor (TNF) inhibitor. Functioning as a soluble TNF receptor, it selectively binds to TNF-alpha molecules present in the bloodstream. This binding action effectively prevents TNF-alpha from interacting with its natural receptors on cell surfaces, thereby disrupting the downstream inflammatory cascade. By acting as a decoy receptor, ENBREL 25MG INJECTION effectively neutralizes the pro-inflammatory effects of TNF-alpha.
  • This neutralization process suppresses the activation of immune cells, which are key players in driving inflammatory responses. Consequently, the production of inflammatory cytokines, such as interleukin-1 (IL-1) and interleukin-6 (IL-6), is significantly reduced. These cytokines contribute to the symptoms and progression of various inflammatory conditions. The targeted disruption of the TNF-alpha pathway by ENBREL 25MG INJECTION leads to a substantial reduction in inflammation and associated symptoms.
  • The precision and specificity of ENBREL 25MG INJECTION in targeting TNF-alpha make it a highly effective therapeutic intervention for managing chronic inflammatory diseases. By modulating the immune response and reducing inflammation, ENBREL 25MG INJECTION helps to alleviate symptoms, improve quality of life, and potentially slow down the progression of these debilitating conditions. Its targeted approach minimizes widespread immunosuppression, reducing the risk of certain side effects compared to broader immunosuppressant medications.

How to use ENBREL 25MG INJECTIONArrow

  • ENBREL 25MG INJECTION offers flexibility in its administration, allowing for both subcutaneous injection and intravenous infusion. Subcutaneous injection involves injecting the medication directly under the skin, typically in areas like the thigh or abdomen. This method is often preferred for its convenience and can be self-administered by patients after proper training and guidance from their healthcare provider.
  • Intravenous infusion, on the other hand, requires administration by a healthcare professional in a clinical setting. The medication is delivered directly into a vein over a specified period. The choice between these two routes depends on several factors, including the specific autoimmune disease being treated, the patient's overall health, and their individual preferences.
  • Both subcutaneous injection and intravenous infusion have demonstrated efficacy in managing autoimmune diseases. Your healthcare provider will assess your condition and determine the most suitable administration route based on your unique needs and circumstances. They will provide detailed instructions on how to administer ENBREL 25MG INJECTION correctly and safely, ensuring optimal therapeutic outcomes.

FAQs

Are there any serious side effects associated with ENBREL 25MG INJECTION?Arrow

Yes, ENBREL 25MG INJECTION may have serious side effects, including an increased risk of serious infections, tuberculosis and hepatitis B reactivation, and rare neurological events. Patients with a history of malignancy or heart failure should also be cautious.

Can I receive vaccinations while on ENBREL 25MG INJECTION?Arrow

Live vaccines should be avoided while on ENBREL 25MG INJECTION treatment due to the risk of infection. Non-live vaccines may have reduced effectiveness, and the timing of vaccinations should be discussed with the healthcare provider.

How often will I need to be monitored while on ENBREL 25MG INJECTION?Arrow

Regular monitoring is essential while on ENBREL 25MG INJECTION therapy. This includes evaluating the response to treatment, assessing for any side effects, and monitoring for signs of infections, liver function, and other potential complications.

Can I discontinue ENBREL 25MG INJECTION if my symptoms improve?Arrow

It is essential not to discontinue ENBREL 25MG INJECTION without consulting your healthcare provider. Stopping the medication abruptly may lead to a flare-up of your condition. Any changes to the treatment plan should be discussed with your healthcare provider.

Can I travel with ENBREL 25MG INJECTION?Arrow

Traveling with ENBREL 25MG INJECTION may be possible, depending on the destination and duration of travel. Some formulations may allow short-term storage at room temperature, while others require refrigeration. Patients should consult with their healthcare provider or pharmacist for specific travel recommendations.

Can I switch to ENBREL 25MG INJECTION from another biologic medication?Arrow

Switching from one biologic medication to another should be done under the guidance of a healthcare provider. The transition may require specific considerations and monitoring to ensure safety and effectiveness.

Does ENBREL 25MG INJECTION interact with other drugs?Arrow

There are no known significant interactions of ENBREL 25MG INJECTION with other drugs. However, it is important to inform your healthcare provider about all medications and supplements you are taking.

What precautions should I take while using ENBREL 25MG INJECTION?Arrow

ENBREL 25MG INJECTION increases the risk of serious infections, including tuberculosis and hepatitis B reactivation, and may lead to neurological events. Patients with a history of malignancy, heart failure, autoimmune disorders, or liver impairment should be closely monitored. Live vaccines should be avoided, and non-live vaccines may have reduced efficacy. Use in pregnant and breastfeeding women should be carefully considered. This medication should not be combined with other biological therapies. Close monitoring and prompt reporting of adverse reactions are essential for safe and effective treatment. Patients scheduled for surgery may need to discontinue the drug temporarily. Regular screening and communication with healthcare providers are vital to managing potential risks and optimizing treatment outcomes.

What molecule is used for making ENBREL 25MG INJECTION?Arrow

ETANERCEPT is the molecule used for making ENBREL 25MG INJECTION.

For which ailments/diseases/conditions is ENBREL 25MG INJECTION prescribed?Arrow

ENBREL 25MG INJECTION is prescribed for ailments/diseases/conditions related to Gastroenterology, Orthopaedics, and Rheumatology.

Is ENBREL 25MG INJECTION safe for children?Arrow

The safety and effectiveness of ENBREL 25MG INJECTION have been established in children, but its use should only be under the supervision of a qualified healthcare provider.

References

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Pfizer, Electronic medicines compendium (EMC)

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Pfizer, US Food and Drug Administration

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Well satisfying products. Generic medicines are way cheaper and of very good quality. Staff is well behaved and knowledgeable.

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Very good and quik responce for all medicines

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Reviewed on 03-01-2023

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(5/5)


Marketer / Manufacturer Details

PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED

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India

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MRP

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₹8333

52.11 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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