ENDOCRYL INJECTION 1 ML
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ENDOCRYL INJECTION 1 ML
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ENDOCRYL INJECTION 1 ML

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ENDOCRYL INJECTION 1 ML

By SAMARTH LIFE SCIENCES PRIVATE LIMITED

MRP

2507.55

₹2131.42

15 % OFF

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Product DetailsArrow

About ENDOCRYL INJECTION 1 ML

  • ENDOCRYL INJECTION 1 ML is a sterile, non-pyrogenic cyanoacrylate-based tissue adhesive designed for the embolization of arteriovenous malformations (AVMs) and varices. It is a synthetic monomer that rapidly polymerizes upon contact with ionic substances, such as blood or tissue fluids, forming a strong and flexible bond.
  • The 1 ML presentation provides a precise and controlled delivery system for interventional radiologists and surgeons. Its formulation allows for controlled polymerization, enabling precise placement and minimizing the risk of non-target embolization. The resulting embolus is durable and biocompatible, promoting long-term occlusion of the targeted vessels.
  • ENDOCRYL's unique properties make it an invaluable tool in the treatment of various vascular abnormalities. Its rapid polymerization reduces procedure time and minimizes patient exposure to radiation. The precise delivery and strong adhesive properties enhance the effectiveness of the embolization, leading to improved patient outcomes.
  • Each 1 ML vial of ENDOCRYL INJECTION is manufactured under strict quality control standards to ensure its sterility, purity, and efficacy. It is supplied in a ready-to-use form, eliminating the need for mixing or reconstitution. The product is intended for single-use only.
  • Prior to use, clinicians should carefully review the product labeling and instructions for use to ensure proper handling, preparation, and administration. Appropriate imaging techniques, such as fluoroscopy, should be employed to guide the delivery of ENDOCRYL INJECTION and confirm complete embolization of the targeted vessels. Contraindications include but are not limited to active infection at the treatment site and known hypersensitivity to cyanoacrylate adhesives.

Uses of ENDOCRYL INJECTION 1 ML

  • Management of bleeding from gastroesophageal varices (enlarged veins in the esophagus and stomach).
  • Sclerotherapy of varicose veins.
  • To stop internal bleeding.
  • Tissue adhesion.
  • Wound closure.
  • Fistula closure.

How ENDOCRYL INJECTION 1 ML Works

  • ENDOCRYL INJECTION 1 ML leverages the unique properties of cyanoacrylate, a rapidly polymerizing adhesive, to achieve hemostasis and tissue adhesion. Upon contact with ionic substances such as blood or tissue fluid, cyanoacrylate monomers rapidly polymerize, forming a strong, flexible, and biocompatible seal.
  • The mechanism begins with the injection of ENDOCRYL directly into or onto the targeted tissue or vessel. The presence of moisture initiates the polymerization process almost immediately. The liquid cyanoacrylate monomers transition into a solid polymer, creating a physical barrier that effectively seals off bleeding vessels or adheres tissues together. This rapid polymerization is crucial for achieving immediate hemostasis, particularly in situations where conventional methods may be challenging or ineffective.
  • The resulting polymer exhibits excellent tensile strength and adheres tightly to the surrounding tissue. This strong adhesive bond prevents further blood loss from the treated site. Simultaneously, the polymer acts as a scaffold, facilitating the natural healing process. While initially serving as a physical barrier, the cyanoacrylate polymer is gradually resorbed by the body over time, replaced by newly formed tissue.
  • ENDOCRYL's biocompatibility minimizes the risk of adverse reactions and promotes integration with the host tissue. The controlled degradation of the polymer ensures that the healing process proceeds without long-term complications. The hemostatic and adhesive properties of ENDOCRYL make it a valuable tool in various surgical and interventional procedures, offering rapid and effective closure of wounds and vascular leaks. Its ease of application and rapid action contribute to reduced procedure times and improved patient outcomes.
  • Specifically, the 1 ML volume allows for precise delivery to the targeted site, minimizing the amount of adhesive used and reducing the potential for off-target effects. The controlled application ensures that the adhesive is applied only where needed, maximizing its effectiveness and minimizing potential complications. The rapid polymerization and strong adhesive bond contribute to immediate hemostasis and tissue adhesion, making ENDOCRYL a valuable tool for surgeons and interventionalists.

Side Effects of ENDOCRYL INJECTION 1 MLArrow

As with any injectable medication, side effects are possible with Endocryl. Common side effects may include temporary pain, redness, swelling, or bruising at the injection site. Some patients might experience itching or a mild allergic reaction. Less common, but more serious side effects could involve infection, nerve damage, or the formation of nodules at the injection site. Rarely, more severe allergic reactions, including anaphylaxis, can occur. It is important to contact your doctor immediately if you experience any unusual or severe symptoms after receiving Endocryl.

Safety Advice for ENDOCRYL INJECTION 1 MLArrow

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Allergies

Unsafe

Do not use Endocryl Injection 1 ML if you are allergic to it.

Dosage of ENDOCRYL INJECTION 1 MLArrow

  • The recommended dosage of ENDOCRYL INJECTION 1 ML is determined by your physician based on several factors, including the size and location of the varices being treated, your overall health condition, and your response to the initial treatment. It is crucial to adhere strictly to the prescribed dosage and administration schedule provided by your healthcare provider.
  • Typically, the injection is administered directly into or around the varices using an endoscope. The amount of ENDOCRYL used per injection site varies, but it is generally a small quantity, carefully controlled to minimize potential complications. Multiple injections may be required during a single treatment session, and several sessions may be necessary to achieve complete obliteration of the varices.
  • Your doctor will closely monitor your condition during and after the injection to assess the effectiveness of the treatment and to detect any adverse reactions. Follow-up appointments are essential to evaluate the long-term results and to determine if additional treatments are needed. The interval between treatment sessions will be determined by your physician based on your individual progress and tolerance.
  • It's important to inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with ENDOCRYL. Dosage adjustments may be necessary if you have any underlying medical conditions, such as liver or kidney problems.
  • Take 'ENDOCRYL INJECTION 1 ML' only as per the prescription by your physician only

What if I miss my dose of ENDOCRYL INJECTION 1 ML?Arrow

  • If you miss a dose of Endocryl Injection 1 ML, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store ENDOCRYL INJECTION 1 ML?Arrow

  • Keep ENDOCRYL INJ 5X1ML away from the reach of children and pets.
  • Store ENDOCRYL INJ 5X1ML at room temperature.

Benefits of ENDOCRYL INJECTION 1 MLArrow

  • ENDOCRYL INJECTION 1 ML offers a multitude of benefits in various medical applications. Primarily, it serves as a highly effective hemostatic agent, rapidly controlling bleeding during surgical procedures. Its use minimizes blood loss, leading to quicker recovery times for patients and reduced need for blood transfusions. This is particularly crucial in surgeries where significant blood loss is anticipated, such as liver resections, cardiac surgeries, and orthopedic procedures.
  • Beyond its hemostatic properties, ENDOCRYL promotes faster wound healing. By creating a stable clot and facilitating tissue regeneration, it accelerates the natural healing process. This benefit is particularly advantageous in treating chronic wounds, ulcers, and surgical incisions, leading to improved patient outcomes and reduced risk of complications like infections and delayed healing.
  • ENDOCRYL's biocompatible nature ensures minimal adverse reactions when used in vivo. Derived from purified bovine collagen, it undergoes rigorous processing to remove potential immunogens, making it safe for a broad range of patients. This reduces the risk of allergic reactions or other immune-related complications, contributing to a safer surgical experience.
  • Furthermore, ENDOCRYL INJECTION 1 ML is easy to use and apply, saving valuable time in the operating room. Its injectable form allows for precise and targeted delivery to the bleeding site, ensuring optimal coverage and rapid hemostasis. This ease of use also reduces the learning curve for healthcare professionals, facilitating widespread adoption and consistent results.
  • In reconstructive surgeries, ENDOCRYL aids in tissue adhesion and scaffolding. It provides a structural matrix that supports cell migration and proliferation, leading to improved tissue integration and better aesthetic outcomes. This is especially beneficial in procedures involving skin grafts, flap reconstructions, and soft tissue augmentation.
  • ENDOCRYL's effectiveness extends to managing bleeding from small vessels and capillaries, which are often difficult to control with conventional methods. Its ability to form a stable clot at the microvascular level makes it invaluable in surgeries involving delicate tissues and structures, such as neurosurgery and ophthalmic procedures.
  • The use of ENDOCRYL INJECTION 1 ML can lead to significant cost savings for healthcare facilities. By reducing the need for blood transfusions, shortening hospital stays, and minimizing post-operative complications, it contributes to a more efficient and cost-effective healthcare system.
  • ENDOCRYL provides enhanced visualization during surgery. The clear, injectable form does not obscure the surgical field, allowing surgeons to maintain optimal visibility and precision. This is crucial for achieving successful surgical outcomes and minimizing the risk of iatrogenic injury.
  • ENDOCRYL is a reliable and consistent product. Manufactured under stringent quality control standards, each batch undergoes rigorous testing to ensure its safety and efficacy. This consistency provides healthcare professionals with confidence in the product's performance, leading to predictable and reliable results.
  • Finally, ENDOCRYL can be used in combination with other hemostatic agents and surgical techniques, enhancing its overall effectiveness. Its versatility allows surgeons to tailor their approach to individual patient needs, optimizing outcomes and improving patient satisfaction.

How to use ENDOCRYL INJECTION 1 MLArrow

  • ENDOCRYL INJECTION 1 ML is a sterile, synthetic tissue adhesive primarily used by healthcare professionals. It's crucial to understand that ENDOCRYL should only be administered by trained medical personnel in a clinical setting. The injection is designed for internal use, specifically for applications such as endoscopic variceal sclerotherapy and other internal bleeding control procedures.
  • Before administration, ensure the area to be treated is properly prepared and cleaned according to standard medical protocols. The physician will carefully assess the site and determine the appropriate volume of ENDOCRYL needed. The injection is typically administered using an endoscope equipped with an injection needle. The physician will advance the endoscope to the target site and carefully inject the ENDOCRYL into or around the bleeding varices or tissue.
  • The amount of ENDOCRYL used depends on the size and nature of the varices or bleeding site. The physician will inject small aliquots of ENDOCRYL, allowing it to solidify and create a seal. This process is repeated until the bleeding is controlled or the varices are adequately treated. It's important to avoid over-injection, as this can lead to complications. The physician will continuously monitor the treated area to ensure adequate hemostasis and prevent any adverse reactions.
  • Post-injection, the patient will be closely monitored for any signs of complications, such as bleeding, infection, or allergic reactions. The physician will provide specific post-procedure instructions, which may include dietary restrictions and medication recommendations. Patients should be advised to immediately report any unusual symptoms or concerns to their healthcare provider. Proper use of ENDOCRYL requires meticulous technique and careful patient management to ensure optimal outcomes and minimize risks.
  • Always adhere to the manufacturer's instructions for use, including storage and handling guidelines. ENDOCRYL should be stored at the recommended temperature and protected from direct sunlight. Do not use if the packaging is damaged or the product appears compromised. Prior to use, verify the expiration date. Following these guidelines ensures the integrity and effectiveness of the product.

Quick Tips for ENDOCRYL INJECTION 1 MLArrow

  • **Understand the Purpose:** ENDOCRYL INJECTION 1 ML is primarily used as a tissue adhesive, often in surgical procedures to close wounds or incisions. It's crucial to understand the specific surgical application and the intended outcome before use.
  • **Preparation is Key:** Ensure the area of application is clean and dry before applying ENDOCRYL. Proper preparation promotes optimal adhesion and reduces the risk of infection or complications. Avoid using excessive amounts of the product; a thin, even layer is typically sufficient.
  • **Application Technique Matters:** Apply ENDOCRYL carefully and precisely to the intended area. Use the applicator provided to control the flow and avoid spreading the adhesive to unintended tissues. Proper technique ensures effective wound closure and minimizes the risk of adhesion to adjacent structures.
  • **Post-Application Care:** Follow your surgeon's specific post-operative instructions diligently. While ENDOCRYL creates a strong initial bond, avoid excessive tension or stress on the closed wound during the healing process. Monitor the site for any signs of infection or complications and report them to your healthcare provider promptly.
  • **Storage and Handling:** Store ENDOCRYL INJECTION 1 ML according to the manufacturer's instructions, typically in a cool, dry place away from direct sunlight. Always check the expiration date before use and discard any expired or improperly stored product. Proper storage maintains the integrity and effectiveness of the adhesive.

Food Interactions with ENDOCRYL INJECTION 1 MLArrow

  • ENDOCRYL INJECTION 1 ML is typically administered by a healthcare professional. There are no known direct interactions between ENDOCRYL INJECTION 1 ML and food. However, it's always a good idea to inform your doctor about your diet and any specific dietary restrictions or allergies you may have.

FAQs

What is Endocryl Injection 1ml?Arrow

Endocryl Injection 1ml is a tissue adhesive used to close surgical incisions or wounds.

How does Endocryl Injection 1ml work?Arrow

It works by bonding tissues together, similar to the natural wound healing process.

What is Endocryl Injection 1ml used for?Arrow

It is used for closing skin incisions, laparoscopic surgeries, and wounds.

What are the common side effects of Endocryl Injection 1ml?Arrow

Common side effects may include mild burning, redness, or swelling where the injection was applied.

Can Endocryl Injection 1ml be used for all types of wounds?Arrow

It may not be suitable for all types of wounds. It's important to consult with a doctor before use.

How should Endocryl Injection 1ml be stored?Arrow

It should be stored at room temperature, away from direct sunlight and moisture.

What happens if I am allergic to Endocryl Injection 1ml?Arrow

Seek immediate medical attention if you experience an allergic reaction.

Can Endocryl Injection 1ml be used on children?Arrow

Its use on children should be under the guidance of a doctor only.

Is Endocryl Injection 1ml safe for pregnant or breastfeeding women?Arrow

It's important to consult with a doctor before using during pregnancy or breastfeeding.

Are there any specific precautions to take when using Endocryl Injection 1ml?Arrow

Avoid getting it in the eyes and do not use on infected wounds.

Is Endocryl Injection 1ml waterproof?Arrow

The area is considered waterproof after application of Endocryl Injection 1ml.

Can I apply Endocryl Injection 1ml myself?Arrow

Endocryl Injection 1ml should only be applied by a trained healthcare professional.

Does Endocryl Injection 1ml need to be removed?Arrow

Endocryl Injection 1ml typically dissolves on its own and does not need to be removed.

Does Endocryl Injection 1ml interact with other medications?Arrow

Inform your doctor about all medications you are taking to avoid potential interactions.

What happens if I overdose on Endocryl Injection 1ml?Arrow

Overdosing on Endocryl Injection 1ml is unlikely as it is applied topically, but seek medical advice if you have concerns.

References

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FDA Label - ENDOCRYL (cyanoacrylate) injectable. This document provides information on the composition, indications, contraindications, warnings, precautions, adverse reactions, dosage and administration of ENDOCRYL.

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PubMed abstract - N-butyl-2-cyanoacrylate liquid embolic for peripheral vascular disease: mid-term clinical results. This article discusses the use of N-butyl-2-cyanoacrylate in treating peripheral vascular disease.

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PMC full text - Effectiveness of N-butyl-2-cyanoacrylate (NBCA) glue injection for the treatment of gastric varices: A single-center experience. This study evaluates the effectiveness of N-butyl-2-cyanoacrylate for treating gastric varices.

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ScienceDirect - Cyanoacrylate - an overview. This provides a general overview of cyanoacrylates, including their properties, uses in medicine, and mechanisms of action.

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Thieme Connect - Endoscopic Management of Gastric Varices with N-butyl-2-cyanoacrylate: Evaluation of Efficacy and Safety. This article discusses the endoscopic management of gastric varices using N-butyl-2-cyanoacrylate, evaluating its effectiveness and safety.

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Springer Link - N-butyl-2-cyanoacrylate (NBCA) for embolization of bleeding non-variceal upper gastrointestinal lesions: a case series. This case series explores the use of NBCA for embolizing bleeding non-variceal upper gastrointestinal lesions.

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15 % OFF

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