ENTACOM PLUS 50MG TABLET 10'S
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ENTACOM PLUS 50MG TABLET 10'SENTACOM PLUS 50MG TABLET 10'S
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ENTACOM PLUS 50MG TABLET 10'S

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ENTACOM PLUS 50MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

98

₹83.3

15 % OFF

₹8.33 Only /

Tablet

10

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Product DetailsArrow

About ENTACOM PLUS 50MG TABLET 10'S

  • ENTACOM PLUS 50MG TABLET 10'S is a medication primarily used in the management of Parkinson's disease. It is a combination medicine containing Levodopa, Carbidopa, and Entacapone. Levodopa is a precursor to dopamine, which helps to replenish the dopamine levels in the brain, as Parkinson's disease is characterized by a deficiency of dopamine.
  • Carbidopa, on the other hand, inhibits the breakdown of Levodopa in the bloodstream, allowing more Levodopa to reach the brain. Entacapone further enhances the effect of Levodopa by blocking an enzyme that breaks down dopamine in the brain. This combination helps to improve motor control and reduce the symptoms associated with Parkinson's disease, such as tremors, rigidity, and slowness of movement.
  • This medication is usually prescribed for individuals who experience 'wearing-off' symptoms, where the effect of Levodopa starts to diminish before the next dose is due. By maintaining more stable levels of dopamine, ENTACOM PLUS 50MG TABLET 10'S can help to prolong the 'on' time and reduce the 'off' time, improving the patient's overall quality of life. It is essential to take this medication exactly as prescribed by your doctor to achieve the best possible results.
  • The typical dosage and administration schedule will be determined by your physician based on individual needs and medical history. Common side effects may include nausea, dyskinesia (involuntary movements), and changes in urine color. It is important to inform your doctor about any other medications you are taking to avoid potential drug interactions. Regular monitoring and follow-up appointments are crucial to ensure the medication is working effectively and to manage any potential side effects.
  • ENTACOM PLUS 50MG TABLET 10'S offers a comprehensive approach to managing Parkinson's symptoms by addressing multiple pathways involved in dopamine metabolism. This synergistic effect allows for better symptom control and improved daily functioning for individuals living with Parkinson's disease.

Uses of ENTACOM PLUS 50MG TABLET 10'S

  • Treatment of Parkinson's disease
  • Management of Parkinson's disease symptoms
  • Treatment of motor fluctuations ('on-off' phenomenon)
  • Enhancing the effect of levodopa
  • Reducing end-of-dose wearing-off phenomenon

How ENTACOM PLUS 50MG TABLET 10'S Works

  • ENTACOM PLUS 50MG TABLET 10'S is a combination medication primarily used in the management of Parkinson's disease. It contains three active ingredients: Levodopa, Carbidopa, and Entacapone, each playing a crucial role in alleviating the symptoms associated with this neurodegenerative disorder.
  • Levodopa is a precursor to dopamine, a neurotransmitter that is deficient in individuals with Parkinson's disease. Dopamine is essential for controlling movement, coordination, and balance. By converting into dopamine in the brain, Levodopa helps replenish the depleted dopamine levels, thus improving motor function and reducing symptoms such as tremors, rigidity, and bradykinesia (slowness of movement).
  • However, when Levodopa is administered alone, a significant portion of it is metabolized in the bloodstream before it can reach the brain. This metabolism reduces the effectiveness of Levodopa and can lead to side effects. This is where Carbidopa comes into play. Carbidopa is a dopa decarboxylase inhibitor. It inhibits the enzyme dopa decarboxylase, which is responsible for breaking down Levodopa in the peripheral tissues (outside the brain). By blocking this enzyme, Carbidopa allows more Levodopa to reach the brain, thereby increasing its bioavailability and therapeutic effect. It also helps in reducing the side effects associated with Levodopa metabolism in the periphery, such as nausea and vomiting.
  • Entacapone is a catechol-O-methyltransferase (COMT) inhibitor. COMT is another enzyme that breaks down Levodopa, but it primarily acts in the brain and peripheral tissues. By inhibiting COMT, Entacapone further reduces the breakdown of Levodopa, both in the brain and in the body. This action prolongs the duration of Levodopa's effect, providing more sustained relief from Parkinson's symptoms. The combined action of Levodopa, Carbidopa, and Entacapone ensures that a higher concentration of Levodopa reaches the brain, remains active for a longer period, and effectively manages the motor symptoms of Parkinson's disease. This synergistic effect allows for better symptom control, reduced fluctuations in motor function (such as 'on-off' periods), and improved quality of life for individuals with Parkinson's disease. It is crucial to take ENTACOM PLUS 50MG TABLET 10'S exactly as prescribed by your doctor to achieve optimal therapeutic benefits.

Side Effects of ENTACOM PLUS 50MG TABLET 10'SArrow

Common side effects of Entacom Plus 50mg Tablet may include: * Nausea * Dizziness * Drowsiness * Headache * Abnormal involuntary movements (dyskinesia) * Confusion * Hallucinations * Dry mouth * Constipation * Diarrhea * Orthostatic hypotension (low blood pressure upon standing) * Insomnia * Vivid dreams or nightmares * Anxiety * Agitation * Changes in urine color (usually harmless reddish-brown) * Muscle cramps * Increased sweating Less common or rare side effects may include: * Cardiac arrhythmias * Changes in liver function tests * Blood dyscrasias (e.g., leukopenia, thrombocytopenia) * Neuroleptic malignant syndrome (NMS) * Rhabdomyolysis * Urinary retention * Impulse control disorders (e.g., compulsive gambling, hypersexuality) * Melanoma (rare association reported)

Safety Advice for ENTACOM PLUS 50MG TABLET 10'SArrow

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Allergies

Allergies

Do not use if you are allergic to this medicine.

Dosage of ENTACOM PLUS 50MG TABLET 10'SArrow

  • The recommended dosage of ENTACOM PLUS 50MG TABLET 10'S varies depending on the individual's condition, severity of symptoms, and response to treatment. It is crucial to adhere to your doctor's instructions precisely. Generally, the starting dose is carefully determined by your physician, and they may adjust it over time to achieve optimal symptom control while minimizing side effects. Never self-adjust your dosage without consulting your doctor.
  • Typically, ENTACOM PLUS 50MG TABLET 10'S is taken orally with or without food. Consistent timing each day helps maintain steady medication levels in your bloodstream. The frequency of administration, whether once, twice, or multiple times daily, is dictated by your specific treatment plan. Swallow the tablet whole with a glass of water; do not crush, chew, or break it unless instructed by your doctor. If you miss a dose, take it as soon as you remember, but if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Your doctor will monitor your progress and adjust your dosage as needed. It's essential to attend all scheduled follow-up appointments. Inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with ENTACOM PLUS 50MG TABLET 10'S. If you experience any unusual or bothersome side effects, promptly notify your doctor. The duration of treatment with ENTACOM PLUS 50MG TABLET 10'S also varies and will be determined by your doctor based on your individual needs and condition. Abruptly stopping the medication without consulting your doctor is not advisable as it can lead to withdrawal symptoms or a worsening of your condition. Take 'ENTACOM PLUS 50MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of ENTACOM PLUS 50MG TABLET 10'S?Arrow

  • If you miss a dose of ENTACOM PLUS 50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the one missed.

How to store ENTACOM PLUS 50MG TABLET 10'S?Arrow

  • Keep ENTACOM PLUS 50MG TAB 1X10 away from the reach of children and pets.
  • Store ENTACOM PLUS 50MG TAB 1X10 at room temperature.

Benefits of ENTACOM PLUS 50MG TABLET 10'SArrow

  • ENTACOM PLUS 50MG TABLET 10'S is a medication primarily used in the management of Parkinson's disease, a progressive neurological disorder that affects movement. Its benefits stem from its unique combination of active ingredients, which work synergistically to alleviate the debilitating symptoms associated with this condition. The primary active ingredients are Levodopa, Carbidopa, and Entacapone. Levodopa is a precursor to dopamine, a neurotransmitter that is deficient in Parkinson's disease. By converting into dopamine in the brain, Levodopa helps to replenish dopamine levels, thereby improving motor control and reducing symptoms such as tremors, rigidity, and bradykinesia (slowness of movement). Carbidopa is a dopa decarboxylase inhibitor. It prevents Levodopa from being broken down in the bloodstream before it reaches the brain. This allows a higher proportion of Levodopa to cross the blood-brain barrier, enhancing its effectiveness and reducing the required dosage. This also minimizes some of the peripheral side effects of Levodopa, such as nausea and vomiting. Entacapone is a catechol-O-methyltransferase (COMT) inhibitor. COMT is an enzyme that breaks down dopamine and Levodopa in the brain and bloodstream. By inhibiting COMT, Entacapone prolongs the duration of action of Levodopa, providing more stable and consistent dopamine levels. This helps to reduce 'wearing-off' effects, where the benefits of Levodopa diminish before the next dose is due. In summary, the combined action of these three components results in significant benefits for individuals with Parkinson's disease. These benefits include improved motor function, reduced tremors and rigidity, enhanced speed of movement, and better overall control of body movements. Patients often experience a greater ability to perform daily activities, leading to an improved quality of life. The medication also helps to manage fluctuations in symptoms, providing more consistent relief throughout the day and reduces the frequency and severity of 'off' episodes, where Parkinson's symptoms return. ENTACOM PLUS 50MG TABLET 10'S, by addressing the underlying dopamine deficiency and optimizing Levodopa's effectiveness, empowers patients to lead more active and fulfilling lives.
  • Improved Motor Function: The combination of Levodopa, Carbidopa, and Entacapone significantly enhances motor control, making movements smoother and more coordinated. This improvement allows patients to perform everyday tasks with greater ease and confidence.
  • Reduced Tremors and Rigidity: By replenishing dopamine levels in the brain, ENTACOM PLUS 50MG TABLET effectively reduces tremors and muscle stiffness, which are hallmark symptoms of Parkinson's disease. This leads to increased comfort and mobility.
  • Enhanced Speed of Movement: Bradykinesia, or slowness of movement, is a common and debilitating symptom of Parkinson's disease. ENTACOM PLUS 50MG TABLET helps to counteract this by improving the speed and fluidity of movements, enabling patients to move more quickly and efficiently.
  • Better Control of Body Movements: The medication provides more stable and consistent control over body movements, reducing the risk of sudden, involuntary movements and improving overall coordination. This increased control allows patients to maintain better balance and stability.
  • Improved Quality of Life: By alleviating the physical symptoms of Parkinson's disease, ENTACOM PLUS 50MG TABLET enables patients to participate more fully in daily activities, social interactions, and recreational pursuits, leading to a significant improvement in their overall quality of life.
  • Management of Fluctuations in Symptoms: The medication helps to manage fluctuations in symptoms, providing more consistent relief throughout the day. This reduces the frequency and severity of 'off' episodes, where Parkinson's symptoms return between doses, allowing patients to maintain a more stable and predictable level of function.

How to use ENTACOM PLUS 50MG TABLET 10'SArrow

  • ENTACOM PLUS 50MG TABLET 10'S is designed to manage symptoms associated with Parkinson's disease. Always adhere to your doctor's instructions regarding dosage and frequency. This medication is typically taken orally, and it can be taken with or without food; however, consistency in timing relative to meals can help maintain stable blood levels of the drug. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this could affect how the medication is released and absorbed in your body.
  • It is crucial to maintain a regular dosing schedule to achieve optimal symptom control. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one. If you have any concerns about missed doses, consult your doctor or pharmacist.
  • While taking ENTACOM PLUS 50MG TABLET 10'S, be aware of potential side effects and interactions with other medications. Inform your doctor about all other medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. This will help prevent any potential drug interactions. Regular monitoring by your doctor is important to assess your response to the medication and to manage any side effects that may arise. Store ENTACOM PLUS 50MG TABLET 10'S at room temperature, away from moisture and heat, and keep it out of reach of children.
  • Be sure to consult your physician or healthcare provider before making any changes to your medication schedule or stopping the medication. Sudden discontinuation can lead to withdrawal symptoms or a worsening of your condition. The dosage is highly dependent on the individual and their disease state and tolerance.

Quick Tips for ENTACOM PLUS 50MG TABLET 10'SArrow

  • Take ENTACOM PLUS 50MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This medication is used to manage Parkinson's disease symptoms, and consistency is key for optimal results.
  • ENTACOM PLUS 50MG TABLET 10'S is typically taken with or without food. However, taking it at the same time each day can help maintain a steady level of medication in your body, which can improve its effectiveness. Be mindful of how food affects you personally and stick to a routine.
  • Be aware of potential side effects. Common side effects of ENTACOM PLUS 50MG TABLET 10'S may include nausea, dizziness, abnormal involuntary movements (dyskinesias), and changes in urine color. Report any troublesome or persistent side effects to your doctor promptly. Do not abruptly stop taking the medicine without medical advice.
  • Monitor your motor fluctuations closely. ENTACOM PLUS 50MG TABLET 10'S helps manage motor symptoms in Parkinson's disease. Keep a journal of when your symptoms are well-controlled (on periods) and when they worsen (off periods). This information will help your doctor fine-tune your treatment plan. It's crucial for adjusting the dosage appropriately. Communicate these observations clearly to your healthcare provider.
  • Inform all your healthcare providers about your medications. Before starting any new medications, including over-the-counter drugs or supplements, inform your doctor or pharmacist that you are taking ENTACOM PLUS 50MG TABLET 10'S. This will help prevent potential drug interactions that could reduce effectiveness or increase side effects. Adhere to all medical advice.
  • Avoid driving or operating machinery if you feel dizzy or drowsy after taking ENTACOM PLUS 50MG TABLET 10'S, until you know how it affects you. This medication can affect your alertness and coordination. Your safety and the safety of others is most important.
  • Store ENTACOM PLUS 50MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective and safe to use.
  • If you miss a dose of ENTACOM PLUS 50MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. If you have repeated missed doses, contact your doctor.
  • ENTACOM PLUS 50MG TABLET 10'S may cause or worsen orthostatic hypotension (a sudden drop in blood pressure upon standing), leading to dizziness or lightheadedness. Rise slowly from a sitting or lying position to minimize this effect. Ensure your hydration levels are good and be extra careful at times like first thing in the morning.
  • Attend all scheduled follow-up appointments with your doctor. Regular check-ups are essential to monitor your response to ENTACOM PLUS 50MG TABLET 10'S, assess for any side effects, and make any necessary adjustments to your treatment plan. Your doctor will periodically review your treatment to ensure it is working effectively and safely.

Food Interactions with ENTACOM PLUS 50MG TABLET 10'SArrow

  • ENTACOM PLUS 50MG TABLET 10'S can be taken with or without food. However, taking it consistently with or without food is recommended to maintain consistent absorption.

FAQs

What is ENTACOM PLUS 50MG TABLET 10'S and what is it used for?Arrow

ENTACOM PLUS 50MG TABLET 10'S is a combination medicine used to treat the symptoms of Parkinson's disease. It works by increasing the levels of dopamine in the body.

What are the active ingredients in ENTACOM PLUS 50MG TABLET 10'S?Arrow

The active ingredients in ENTACOM PLUS 50MG TABLET 10'S are Levodopa, Carbidopa, and Entacapone.

How should I take ENTACOM PLUS 50MG TABLET 10'S?Arrow

Take ENTACOM PLUS 50MG TABLET 10'S as prescribed by your doctor. It can be taken with or without food. Swallow the tablet whole, do not chew or crush it.

What are the common side effects of ENTACOM PLUS 50MG TABLET 10'S?Arrow

Common side effects of ENTACOM PLUS 50MG TABLET 10'S include nausea, vomiting, dizziness, drowsiness, involuntary movements (dyskinesia), and changes in urine color.

Can ENTACOM PLUS 50MG TABLET 10'S interact with other medications?Arrow

ENTACOM PLUS 50MG TABLET 10'S can interact with certain medications, such as MAOIs, tricyclic antidepressants, and iron supplements. Inform your doctor about all the medications you are taking.

How should I store ENTACOM PLUS 50MG TABLET 10'S?Arrow

Store ENTACOM PLUS 50MG TABLET 10'S at room temperature, away from heat and moisture. Keep out of reach of children and pets.

Is ENTACOM PLUS 50MG TABLET 10'S safe during pregnancy or breastfeeding?Arrow

The safety of ENTACOM PLUS 50MG TABLET 10'S during pregnancy or breastfeeding has not been established. Talk to your doctor if you are pregnant or breastfeeding.

What happens if I miss a dose of ENTACOM PLUS 50MG TABLET 10'S?Arrow

If you miss a dose of ENTACOM PLUS 50MG TABLET 10'S, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Is it normal for ENTACOM PLUS 50MG TABLET 10'S to cause urine discoloration?Arrow

Yes, it is normal for ENTACOM PLUS 50MG TABLET 10'S to cause urine discoloration. This is due to the medication and is not a cause for concern.

Can I drink alcohol while taking ENTACOM PLUS 50MG TABLET 10'S?Arrow

Drinking alcohol while taking ENTACOM PLUS 50MG TABLET 10'S can increase the risk of side effects such as dizziness and drowsiness. Talk to your doctor before consuming alcohol.

How long does it take for ENTACOM PLUS 50MG TABLET 10'S to start working?Arrow

It may take a few weeks for ENTACOM PLUS 50MG TABLET 10'S to start working. Be patient and continue taking the medication as prescribed by your doctor.

What happens if I overdose on ENTACOM PLUS 50MG TABLET 10'S?Arrow

If you think you have taken too much ENTACOM PLUS 50MG TABLET 10'S, seek medical attention immediately.

Is it safe to stop taking ENTACOM PLUS 50MG TABLET 10'S suddenly?Arrow

Do not stop taking ENTACOM PLUS 50MG TABLET 10'S suddenly. Doing so can cause withdrawal symptoms. Talk to your doctor before stopping your medication.

Is ENTACOM PLUS 50MG TABLET 10'S suitable for everyone?Arrow

ENTACOM PLUS 50MG TABLET 10'S may not be suitable for everyone. Tell your doctor about your medical history and all the medications you are taking to ensure it is safe for you.

Are there any long-term side effects of ENTACOM PLUS 50MG TABLET 10'S?Arrow

Long-term side effects of ENTACOM PLUS 50MG TABLET 10'S may include dyskinesia (involuntary movements), psychosis, and other mental health changes. Discuss these risks with your doctor.

References

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European Medicines Agency (EMA) - Entacapone EPAR: Provides detailed scientific assessment reports on entacapone-containing medicinal products.

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FDA Drugs@FDA: Searchable database for approved drug products, including those containing entacapone. Look for relevant New Drug Applications (NDAs).

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PubMed: Search engine for biomedical literature. Use search terms like 'entacapone' 'pharmacokinetics' 'clinical trials' 'mechanism of action' to find relevant research articles.

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ScienceDirect: A comprehensive database providing access to scientific, technical and medical research. Use keywords like 'entacapone' and related terms to find relevant articles.

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UpToDate: Clinical resource that provides drug information, including entacapone. (Subscription required)

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DrugBank: Detailed information about entacapone, including its chemical structure, mechanism of action, and pharmacological properties.

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RxList - Comtan: Provides information on the brand-name version of entacapone, including side effects, dosages, and interactions.

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Very responsive staff.All drugs available at store

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Discount on medicine is good But OTC discount is zero and very low

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(3/5)


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INTAS PHARMACEUTICALS LIMITED

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India

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ENTACOM PLUS 50MG TABLET 10'S

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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