ESIFLO 125 TRANSHALER 120 MD

How ESIFLO 125 TRANSHALER 120 MD Works

• ESIFLO 125 TRANSHALER 120 MD is a combination medication containing fluticasone propionate and salmeterol xinafoate, both delivered directly to the lungs via inhalation. This dual-action approach addresses the underlying causes of respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD) by reducing inflammation and opening airways for easier breathing.
• Fluticasone propionate, a corticosteroid, is a potent anti-inflammatory agent. When inhaled, it directly targets the airways, suppressing the release of inflammatory substances such as cytokines and leukotrienes. These substances contribute to airway swelling, mucus production, and bronchospasm (narrowing of the airways). By reducing inflammation, fluticasone helps to prevent asthma attacks and COPD exacerbations, leading to improved lung function and reduced symptoms like wheezing, coughing, and shortness of breath. Regular use of fluticasone helps to build a foundation of reduced inflammation in the airways, making them less reactive to triggers such as allergens, irritants, or exercise.
• Salmeterol xinafoate is a long-acting beta2-adrenergic agonist (LABA). It works by stimulating beta2 receptors in the smooth muscle cells lining the airways. This stimulation causes the muscles to relax, leading to bronchodilation (widening of the airways). The bronchodilating effect of salmeterol helps to relieve symptoms like wheezing, chest tightness, and shortness of breath, making it easier to breathe. Unlike short-acting bronchodilators, salmeterol provides sustained bronchodilation for up to 12 hours, offering long-lasting relief and improved symptom control. It's important to note that salmeterol is not intended for the relief of sudden asthma symptoms; it's primarily used for long-term maintenance therapy in conjunction with an inhaled corticosteroid.
• The combination of fluticasone and salmeterol in ESIFLO 125 TRANSHALER offers a synergistic effect. Fluticasone reduces inflammation, addressing the underlying cause of airway obstruction, while salmeterol provides long-lasting bronchodilation to relieve symptoms and improve airflow. This combination provides comprehensive control of asthma and COPD, leading to improved lung function, reduced exacerbations, and a better quality of life for patients. The TRANSHALER device ensures consistent and reliable delivery of the medication directly to the lungs, maximizing its effectiveness and minimizing systemic side effects.
• It is crucial to use ESIFLO 125 TRANSHALER 120 MD exactly as prescribed by your doctor. Do not increase the dose or use it more frequently than recommended, as this can increase the risk of side effects. If your symptoms worsen or you need to use your rescue inhaler more often, contact your doctor immediately.

Like all medicines, ESIFLO 125 TRANSHALER 120 MD can cause side effects, although not everybody gets them. Common side effects include: Sore throat, Hoarseness, Cough, Oral thrush (a fungal infection in the mouth). Uncommon side effects include: Headache, Nausea, Vomiting, Dizziness, Difficulty sleeping, Restlessness, Agitation, Tremor, Muscle cramps, Palpitations (fast or irregular heartbeat), Skin rash, Itching, Urticaria (hives). Rare side effects include: Paradoxical bronchospasm (wheezing or difficulty breathing immediately after using the inhaler), Allergic reactions (including swelling of the face, lips, tongue, or throat), Hyperglycemia (increased blood sugar levels), Hypokalemia (low potassium levels), Glaucoma (increased pressure in the eye), Cataracts, Osteoporosis (weakening of the bones), Cushing's syndrome (a hormonal disorder). Very rare side effects include: Depression, Anxiety, Changes in behavior, Increased intraocular pressure.

• If you miss a dose of ESIFLO 125 TRANSHALER 120 MD, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep ESIFLO 125 TRANSHALER 120MD away from the reach of children and pets.
• Store ESIFLO 125 TRANSHALER 120MD at room temperature.

• **Understand Your Inhaler:** ESIFLO 125 Transhaler is a dry powder inhaler (DPI). Ensure you know how to load a dose and inhale correctly. Your pharmacist or doctor can demonstrate the proper technique. Consistent correct usage maximizes the medicine's effectiveness in managing your asthma or COPD.
• **Prime the Inhaler (If Necessary):** Some DPIs need to be primed before the first use or after a period of non-use. Refer to the product leaflet for specific priming instructions for your ESIFLO 125 Transhaler. Priming ensures you receive the correct dose when you start using it.
• **Maintain a Consistent Inhalation Technique:** Breathe in deeply and forcefully through the inhaler to ensure the powder reaches your lungs. A slow, gentle inhalation will not deliver the medication effectively. Hold your breath for as long as comfortable (around 10 seconds) after inhaling to allow the medication to settle in your lungs, then breathe out slowly. Don't exhale into the inhaler.
• **Rinse Your Mouth After Each Use:** ESIFLO 125 Transhaler contains a corticosteroid (fluticasone). Rinsing your mouth with water and spitting it out after each use helps prevent oral thrush (a fungal infection in the mouth) and reduces the risk of hoarseness. Do not swallow the water after rinsing.
• **Clean Your Inhaler Regularly:** Keep your ESIFLO 125 Transhaler clean and dry. Wipe the mouthpiece with a dry cloth regularly to remove any powder residue. Do not wash the inhaler with water, as this can damage the device and affect its performance. Store it in a cool, dry place away from direct sunlight and moisture. Check the expiration date and replace the inhaler when it expires.

• There are no known significant food interactions associated with ESIFLO 125 TRANSHALER 120 MD. However, it's essential to maintain a healthy diet and avoid any foods that may trigger asthma or COPD symptoms.