FENOTORVA 10MG TABLET 10'S

How FENOTORVA 10MG TABLET 10'S Works

• FENOTORVA 10MG TABLET 10'S is a combination medication containing fenofibrate and atorvastatin, working synergistically to address multiple lipid parameters and reduce the risk of cardiovascular events. Atorvastatin, a member of the statin family, primarily inhibits the enzyme HMG-CoA reductase in the liver. This enzyme is crucial in the synthesis of cholesterol. By blocking HMG-CoA reductase, atorvastatin reduces the production of cholesterol within liver cells. This reduction triggers a compensatory mechanism where liver cells increase the number of LDL receptors on their surface. These receptors bind to LDL cholesterol circulating in the bloodstream, effectively removing it from circulation. This process leads to a significant decrease in LDL cholesterol levels, often referred to as 'bad' cholesterol, which is a major contributor to the formation of plaque in arteries (atherosclerosis).
• Fenofibrate, on the other hand, belongs to a class of drugs called fibrates. Its main mechanism of action involves activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). PPARα is found in various tissues, including the liver and muscles. When activated by fenofibrate, PPARα increases the production of lipoprotein lipase (LPL). LPL is an enzyme that breaks down triglycerides, a type of fat found in the blood. By increasing LPL activity, fenofibrate helps lower triglyceride levels. Furthermore, activation of PPARα also increases the production of apolipoprotein A-I (apoA-I), a major component of high-density lipoprotein (HDL), often called 'good' cholesterol. Higher levels of HDL cholesterol help remove cholesterol from the arteries, reducing the risk of heart disease.
• The combined action of atorvastatin and fenofibrate provides a comprehensive approach to managing dyslipidemia (abnormal lipid levels). Atorvastatin primarily targets LDL cholesterol, while fenofibrate focuses on reducing triglycerides and increasing HDL cholesterol. This dual action makes FENOTORVA 10MG TABLET 10'S particularly beneficial for individuals with mixed dyslipidemia, where both LDL cholesterol and triglyceride levels are elevated, and HDL cholesterol may be low. By addressing multiple lipid parameters, FENOTORVA 10MG TABLET 10'S significantly reduces the risk of atherosclerosis, heart attack, stroke, and other cardiovascular complications. It's crucial to remember that this medication is most effective when used in conjunction with a healthy lifestyle, including a balanced diet, regular exercise, and smoking cessation. Always follow your doctor's instructions regarding dosage and duration of treatment.

The following side effects have been reported with Fenotorva (Atorvastatin/Fenofibrate). Not everyone experiences these, and their severity can vary: **Common Side Effects (may affect up to 1 in 10 people):** * Headache * Abdominal pain * Nausea * Diarrhea * Constipation * Flatulence * Muscle pain * Joint pain * Back pain * Elevated liver enzymes * Increased creatine phosphokinase (CPK) in blood **Uncommon Side Effects (may affect up to 1 in 100 people):** * Vomiting * Fatigue * Weakness * Indigestion * Rash * Itching * Hives * Muscle inflammation * Muscle cramps * Numbness or tingling in the extremities * Sleep disturbances (insomnia) * Hair loss * Dizziness * Pancreatitis * Gallstones * Increased blood urea * Increased creatinine **Rare Side Effects (may affect up to 1 in 1,000 people):** * Severe muscle damage (rhabdomyolysis) * Liver problems (hepatitis, jaundice) * Hypersensitivity reactions (allergic reactions) * Angioedema (swelling of the face, lips, tongue, or throat) **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Liver failure * Autoimmune myopathy (immune-mediated muscle disease) **Side Effects with Unknown Frequency (frequency cannot be estimated from available data):** * Erectile dysfunction * Depression * Memory loss * Peripheral neuropathy (nerve damage in hands and feet) * Interstitial lung disease **Important Note:** This is not a complete list. If you experience any unusual symptoms while taking Fenotorva, contact your doctor immediately.

• If you miss a dose of FENOTORVA 10MG TABLET 10'S, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for the one you missed.

• Keep FENOTORVA 10MG TAB 1X10 away from the reach of children and pets.
• Store FENOTORVA 10MG TAB 1X10 at room temperature.

• Take FENOTORVA 10MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this could affect its effectiveness and potentially lead to adverse effects on your lipid levels. Consistency is key to managing your cholesterol and triglyceride levels effectively.
• While taking FENOTORVA 10MG TABLET 10'S, maintain a heart-healthy lifestyle. This includes following a balanced diet low in saturated and trans fats, cholesterol, and refined sugars. Regular physical activity, such as brisk walking, jogging, or swimming, for at least 30 minutes most days of the week can significantly improve your cardiovascular health and complement the effects of the medication. Also, avoid smoking and limit alcohol consumption.
• Be aware of potential side effects of FENOTORVA 10MG TABLET 10'S. Common side effects may include muscle pain or weakness, stomach upset, nausea, or headache. If you experience any persistent or severe side effects, especially unexplained muscle pain, tenderness, or weakness, accompanied by fever or fatigue, contact your doctor immediately. These symptoms could indicate a rare but serious condition called rhabdomyolysis.
• Schedule regular blood tests as directed by your doctor. FENOTORVA 10MG TABLET 10'S can affect your liver function, so it's important to monitor your liver enzymes through blood tests. These tests help your doctor ensure the medication is working effectively and to detect any potential liver problems early on. Regular monitoring also helps to track your cholesterol and triglyceride levels to assess the medication's impact on your lipid profile.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting FENOTORVA 10MG TABLET 10'S. Certain medications can interact with fenofibrate, potentially increasing the risk of side effects or reducing its effectiveness. This includes other cholesterol-lowering drugs, blood thinners, and certain immunosuppressants. Providing a complete list of your medications helps your doctor make informed decisions about your treatment plan.