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Composition
Content Reviewed By:
Dr. Anil Gupta
, (MBBS)
Written By:
Mr. Ankit Jain
, (B.Pharm)
Most side effects are temporary and usually disappear as your body gets used to the medicine. However, if they continue or become bothersome, it is important to seek advice from your doctor.

Other Medical Conditions and Interactions
Special precautionsPatients with known dihydropyrimidine dehydrogenase (DPD) deficiency may be at increased risk of systemic toxicity from fluorouracil, even with topical use. Such patients should use Flonida 1 Cream only under close specialist supervision, if at all.
FLONIDA 1% CREAM 10 GM is used for treating actinic keratosis, which refers to rough, red, scaly, or crusty spots on the skin that are caused by excessive exposure to sunlight. They are mostly seen on sun-exposed areas, such as the face, nose, ears, chest, forearms, and back of the hands. These spots are usually harmless, but they have the potential to eventually turn into skin cancer at a later stage.
Use of FLONIDA 1% CREAM 10 GM should be avoided in patients who are allergic to FLONIDA 1% CREAM 10 GM or any of its components. However, if you are not aware of any allergy, or if you are using FLONIDA 1% CREAM 10 GM for the first time, consult your doctor.
Before using FLONIDA 1% CREAM 10 GM, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If FLONIDA 1% CREAM 10 GM gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.
No, do not stop using FLONIDA 1% CREAM 10 GM without consulting your doctor even if you are feeling better. Your symptoms may improve before your condition is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.
FLONIDA 1% CREAM 10 GM is safe if used in the dose and duration advised by your doctor. Use it exactly as directed by the doctor to get the most benefit. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Yes, FLONIDA 1% CREAM 10 GM can cause an allergic reaction. It is considered to be harmful for patients with known allergy to fluorouracil, the active ingredient or to any of the other ingredients of FLONIDA 1% CREAM 10 GM. Get emergency medical help if you have any signs of allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue or throat.
Be careful not to get FLONIDA 1% CREAM 10 GM into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use FLONIDA 1% CREAM 10 GM if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly, to prevent any allergic reaction with other medicines. Do not cover the area being treated with FLONIDA 1% CREAM 10 GM with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive. Pregnant and breastfeeding mothers should use FLONIDA 1% CREAM 10 GM only if prescribed by the doctor.
If you forget to use FLONIDA 1% CREAM 10 GM, do not worry and continue using FLONIDA 1% CREAM 10 GM as soon as you remember. However, if you are not sure and have any other doubts, please consult your doctor.
Flonida 1 Cream is a prescription topical medicine used to treat certain precancerous and superficial cancerous skin conditions. Its active ingredient is fluorouracil 1% w/w, an antimetabolite that interferes with DNA and RNA synthesis in rapidly dividing abnormal skin cells, leading to their destruction.
Flonida 1 Cream is commonly prescribed for actinic keratosis (solar keratosis) and for some superficial forms of basal cell carcinoma, as well as other fluorouracil‑responsive premalignant or malignant skin lesions. The exact indication depends on the dermatologist’s assessment, and it should not be used for routine cosmetic purposes such as acne or simple pigmentation.
Flonida 1 Cream should be applied as a thin layer to the affected skin area only, as directed by your doctor. The skin should usually be clean and dry before application. Avoid contact with eyes, mouth, nostrils, and mucous membranes. Wash your hands thoroughly after applying the cream, unless your hands are the area being treated. Do not cover the area with occlusive dressings unless your doctor specifically instructs you to do so.
The time to see results varies with the condition being treated, the size and location of the lesion, and individual skin response. Many patients experience redness, irritation, and crusting within days to weeks of starting therapy, followed by gradual healing after treatment is stopped. Your doctor will determine the appropriate duration of therapy and will review your skin periodically to assess response.
Common side effects include redness, burning, stinging, itching, dryness, scaling, crusting, and mild pain at the application site. These reactions are often expected and indicate that the medicine is acting on abnormal cells. However, severe pain, intense inflammation, ulceration, blistering, or signs of infection should be reported to your doctor promptly.
Flonida 1 Cream may be prescribed for facial lesions such as actinic keratoses, but it must be used with great care and only under specialist supervision. It should not be applied on or too close to the eyelids, inside the nose, or on the lips unless your doctor specifically instructs you. Accidental contact with the eyes or mucous membranes should be rinsed immediately with plenty of water and medical advice should be sought.
Fluorouracil, the active ingredient in Flonida 1 Cream, is potentially harmful to a developing fetus. Use during pregnancy is generally not recommended unless the potential benefit clearly outweighs the risk and a specialist has advised it. Women who are pregnant, planning pregnancy, or could become pregnant should discuss contraception and treatment alternatives with their doctor before starting therapy.
The safety of topical fluorouracil during breastfeeding is not well established. Systemic absorption from the skin is usually low but may increase if large areas or damaged skin are treated. As a precaution, breastfeeding women should consult their doctor before using Flonida 1 Cream. If it is prescribed, it should not be applied to the breast area or any skin that may come into direct contact with the infant.
Yes. The treated skin can become more sensitive to sunlight and may burn or react more severely if exposed to ultraviolet radiation. During treatment and for some time after, you should minimize sun exposure, use protective clothing such as hats and long sleeves, and apply a broad‑spectrum sunscreen to unaffected skin as advised by your doctor. Do not apply sunscreen over the treated area unless your doctor specifically recommends it.
If you miss a scheduled application, apply the cream as soon as you remember, unless it is almost time for your next application. In that case, skip the missed dose and resume your regular schedule. Do not apply extra cream to make up for a missed application, as this may increase local irritation without improving effectiveness. If you frequently forget doses, discuss this with your doctor so your regimen can be reviewed.
Use of Flonida 1 Cream in children is uncommon and should only occur under the guidance of a specialist experienced in pediatric dermatology or oncology. Safety and efficacy data in children are limited, and the risk of local and systemic side effects may be higher, especially if large areas are treated. Never use this medicine on a child without explicit medical advice.
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