FLUTICONE OX NASAL SPRAY 7 GM

How FLUTICONE OX NASAL SPRAY 7 GM Works

• FLUTICONE OX NASAL SPRAY 7 GM is a combination medication designed to relieve nasal congestion and inflammation associated with allergies and other nasal conditions. It contains two active ingredients: fluticasone propionate and oxymetazoline hydrochloride. Understanding how each of these components works is crucial to appreciating the overall effectiveness of the spray.
• Fluticasone propionate is a corticosteroid, which means it belongs to a class of drugs that mimic the effects of cortisol, a hormone naturally produced by the adrenal glands. In the context of nasal sprays, fluticasone acts as a potent anti-inflammatory agent. When sprayed into the nasal passages, fluticasone binds to glucocorticoid receptors in the nasal mucosa (the lining of the nose). This binding initiates a cascade of intracellular events that ultimately lead to a reduction in inflammation.
• Specifically, fluticasone works by inhibiting the production and release of various inflammatory mediators, such as cytokines, chemokines, and histamine. These mediators are responsible for the symptoms of nasal inflammation, including swelling, redness, itching, and increased mucus production. By suppressing their activity, fluticasone effectively reduces nasal congestion and alleviates allergy symptoms like sneezing, runny nose, and itchy eyes.
• Oxymetazoline hydrochloride, on the other hand, is a decongestant that belongs to a class of drugs called alpha-adrenergic agonists. It works by directly stimulating alpha-adrenergic receptors located on the blood vessels in the nasal passages. When oxymetazoline binds to these receptors, it causes the blood vessels to constrict, a process known as vasoconstriction.
• The vasoconstriction effect of oxymetazoline reduces blood flow to the nasal mucosa, which in turn decreases swelling and congestion. This allows for improved airflow through the nasal passages, making it easier to breathe. The decongestant effect of oxymetazoline provides rapid relief from nasal stuffiness, but it is important to note that it only addresses the symptom of congestion and does not treat the underlying cause of the inflammation.
• The combination of fluticasone and oxymetazoline in FLUTICONE OX NASAL SPRAY 7 GM provides a dual-action approach to nasal relief. Fluticasone addresses the underlying inflammation that contributes to nasal congestion and allergy symptoms, while oxymetazoline provides rapid and temporary relief from nasal stuffiness. This combination can be particularly beneficial for individuals experiencing both inflammation and congestion, as it targets both aspects of the condition.
• It is crucial to use FLUTICONE OX NASAL SPRAY 7 GM as directed by a healthcare professional. Overuse of oxymetazoline-containing decongestants can lead to rebound congestion, a condition in which the nasal passages become even more congested after the medication is stopped. Fluticasone, as a corticosteroid, also requires consistent use to achieve its full anti-inflammatory effects. Therefore, adherence to the prescribed dosage and duration of treatment is essential for optimal results and to minimize the risk of side effects.

Like all medicines, FLUTICONE OX NASAL SPRAY 7 GM can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Nosebleeds * Nasal ulceration * Headache **Uncommon side effects (may affect up to 1 in 100 people):** * Nasal burning * Nasal stinging * Nasal dryness * Coughing * Sneezing **Rare side effects (may affect up to 1 in 1,000 people):** * Perforation of the nasal septum (hole in the cartilage separating the nostrils) **Very rare side effects (may affect up to 1 in 10,000 people):** * Glaucoma * Increased intraocular pressure * Cataracts * Hypersensitivity reactions, including rash, itching, hives, and angioedema (swelling of the face, tongue, or throat) * Anaphylaxis (severe allergic reaction) **Other potential side effects (frequency not known):** * Slowed growth rate in children and adolescents * Adrenal suppression * Blurred vision If you experience any of these or other worrying side effects, stop using FLUTICONE OX NASAL SPRAY 7 GM and talk to your doctor or pharmacist.

• If you miss a dose of Fluticasone OX Nasal Spray, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one.

• Keep FLUTICONE OX NASAL SPRAY 7GM away from the reach of children and pets.
• Store FLUTICONE OX NASAL SPRAY 7GM at room temperature.

• **1. Prime the Pump:** Before your first use of Fluticasone Ox Nasal Spray, and after any extended period of non-use (a week or more), prime the pump. This ensures you receive the correct dose. To prime, hold the spray upright and pump the nozzle into the air several times (usually 5-6) until a fine mist is released. Avoid spraying it towards your face.
• **2. Proper Nasal Administration:** Gently blow your nose to clear your nostrils before using the spray. Tilt your head slightly forward. Insert the nozzle into one nostril, aiming towards the outside of your nose, away from the septum (the cartilage dividing your nostrils). Spray once or twice as directed by your doctor, and gently sniff. Repeat in the other nostril. Avoid blowing your nose for at least 15 minutes after use to allow the medication to absorb.
• **3. Consistent Usage is Key:** For best results, use Fluticasone Ox Nasal Spray regularly and consistently, as prescribed by your doctor, even when you feel better. It may take several days to a week to experience the full effects of the medication. Do not stop using it abruptly without consulting your doctor, as your symptoms may return or worsen.
• **4. Hygiene Matters:** To prevent the spread of infection, always keep the nozzle clean. Rinse the nozzle with warm water and dry it thoroughly after each use. Do not share your nasal spray with others, as this can spread germs and infections. Replace the cap tightly after each use to prevent contamination.
• **5. Be Patient and Monitor Side Effects:** Fluticasone Ox Nasal Spray is a long-term treatment for nasal congestion and inflammation. It may take several days to a week to notice significant improvement. While generally safe, some potential side effects include nasal irritation, nosebleeds, headache, or a sore throat. If you experience severe or persistent side effects, consult your doctor promptly.

• FLUTICONE OX NASAL SPRAY 7 GM is generally not affected by food. It can be used regardless of meals. However, if you experience any stomach upset, taking it with food might help.